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Clinical trials for Liver Disease

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    4,648 result(s) found for: Liver Disease. Displaying page 3 of 233.
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    EudraCT Number: 2007-002105-44 Sponsor Protocol Number: ML20982 Start Date*: 2008-07-02
    Sponsor Name:Military Medical Academy Hospital for Active Treatment, Sofia
    Full Title: Open – label, non randomized clinical study of Neoadjuvant chemotherapy with FOLFIRI and Avastin in patients with non-resectable liver metastases of colorectal cancer
    Medical condition: Metastatic (liver metastases) colorectal cancer, with no prior chemotherapy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024700 Liver metastases LLT
    9.1 10052358 Colorectal cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022660-12 Sponsor Protocol Number: PRAISE_ZKS0006 Start Date*: 2011-02-02
    Sponsor Name:Friedrich Schiller University
    Full Title: A prospective, multi-center, randomized, double blinded, placebo-controlled study for the evaluation of Iloprost in the early postoperative period after liver transplantation
    Medical condition: the early postoperative period after liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10024716 Liver transplantation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-004644-28 Sponsor Protocol Number: 13-129 Start Date*: Information not available in EudraCT
    Sponsor Name:RWTH Aachen University, represented by the Rector, himself, represented by the Dean of the Medical Faculty
    Full Title: Administration of Rifaximin to improve Liver Regeneration and Outcome following Major Liver Resection
    Medical condition: Patients undergoing major liver resection will be included into the study
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-002924-11 Sponsor Protocol Number: LOLAbiome Start Date*: 2023-01-09
    Sponsor Name:CBmed GmbH
    Full Title: An observational study on the effect of L-ornithine-L-aspertate (LOLA) on the Flavonifractor abundance in the gut microbiome in liver cirrhosis
    Medical condition: Liver cirrhosis with covert or overt hepatic encephalopathy (grade 0-2)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10024667 Liver cirrhosis LLT
    20.0 100000004852 10014630 Encephalopathy hepatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001617-34 Sponsor Protocol Number: FG-506-01-27 Start Date*: 2005-03-07
    Sponsor Name:Astellas Pharma GmbH
    Full Title: AN OPEN, RANDOMISED, MULTICENTRE, CLINICAL STUDY TO COMPARE THE SAFETY AND EFFICACY OF TACROLIMUS AND MINIMAL STEROIDS IN COMBINATION WITH EITHER A MONOCLONAL ANTI-IL2R ANTIBODY (DACLIZUMAB) OR MYC...
    Medical condition: Patients with hepatic disease who will undergo primary orthotopic liver or split liver allograft transplantation.
    Disease: Version SOC Term Classification Code Term Level
    7.0 10019650 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) SE (Completed) FI (Completed) DK (Completed) ES (Completed) IT (Completed) BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022730-91 Sponsor Protocol Number: BR1-130 Start Date*: 2011-10-14
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: Characterization of focal liver lesions with Sonovue(R)-enhanced ultrasound imaging: a phase III, intrapatient comparative study versus unenhanced ultrasound imaging using histology or combined ...
    Medical condition: At least one focal liver lesion requiring further work-up for complete characterization.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10024718 Liver tumor NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-003920-40 Sponsor Protocol Number: IG0802 Start Date*: 2009-02-06
    Sponsor Name:Instituto Grifols, S.A.
    Full Title: ESTUDIO CLÍNICO SOBRE LOS EFECTOS DE LA ADMINISTRACIÓN PROLONGADA DE ALBUMINA 20% SOBRE LA FUNCIÓN CARDIOCIRCULATORIA Y RENAL, Y LA HEMODINAMICA HEPATICA EN PACIENTES CON CIRROSIS AVANZADA Y ASCITIS
    Medical condition: Cirrosis hepática
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024667 Liver cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-011437-27 Sponsor Protocol Number: MAFRI Start Date*: 2009-10-27
    Sponsor Name:Fundació Clínic
    Full Title: EFECTO DE LA ADMINISTRACIÓN DE ALBÚMINA INTRAVENOSA Y MIDODRINA ORAL SOBRE LA FUNCIÓN RENAL DE LOS PACIENTES CON CIRROSIS HEPÁTICA Y INSUFICIENCIA RENAL FUNCIONAL
    Medical condition: mejorar la disfunción circulatória en pacientes con cirrosis hepática
    Disease: Version SOC Term Classification Code Term Level
    9 10009213 Cirrhosis of liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003349-41 Sponsor Protocol Number: ERASMECMI Start Date*: 2013-10-03
    Sponsor Name:Erasme hospital
    Full Title: what are the optimal doses of cefuroxime for cirrhotic patients?
    Medical condition: Cirrhotic patients with infection requiring treatment with cefuroxime
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004871 10024678 Liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2017-001581-20 Sponsor Protocol Number: IRRB/72/14 Start Date*: 2018-02-08
    Sponsor Name:ISTITUTO MEDITERRANEO PER I TRAPIANTI E TERAPIE AD ALTA SPECIALIZZAZIONE - ISMETT
    Full Title: THE ADDITION OF SIMVASTATIN ADMINISTRATION TO COLD STORAGE SOLUTION OF EXPLANTED WHOLE LIVER GRAFTS FOR FACING ISCHEMIA/REPERFUSION INJURY IN AN AREA WITH LOW RATE OF DECEASED DONATION. A MONOCENT...
    Medical condition: ISCHEMIC REPERFUSION INJURY AFTER LIVER TRANSPLANTATION: HEPATIC ISCHEMIA AND REPERFUSION INJURY REPRESENTS THE MAIN UNDERLYING MECHANISM FOR GRAFT DYSFUNCTION, AND FAILURE, POST-TRANSPLANTATION. H...
    Disease: Version SOC Term Classification Code Term Level
    21.1 10047065 - Vascular disorders 10063837 Reperfusion injury PT
    20.0 10042613 - Surgical and medical procedures 10024714 Liver transplant PT
    20.1 10022117 - Injury, poisoning and procedural complications 10058060 Graft complication PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000232-34 Sponsor Protocol Number: NASIR-HCC Start Date*: 2017-09-11
    Sponsor Name:Clínica Universidad de Navarra/Universidad de Navarra
    Full Title: A multicenter, open-label, single-arm study of the safety and antitumoral efficacy of nivolumab in combination with selective internal radiation therapy (SIRT) using SIR-Spheres for the treatment o...
    Medical condition: Hepatocellular carcinoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10073071 Hepatocellular carcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-012570-13 Sponsor Protocol Number: BAY73-4506/14596 Start Date*: 2009-08-25
    Sponsor Name:Bayer HealthCare AG, D51368 Leverkusen
    Full Title: An uncontrolled open label multicenter phase II safety study of BAY 73-4506 in patients with hepatocellular carcinoma (HCC)
    Medical condition: Hepatocellular carcinoma, in patients who have failed (experienced radiological progression) previous treatment cancer
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10049010 Carcinoma hepatocellular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004031-23 Sponsor Protocol Number: E2012AILIVER Start Date*: 2014-08-26
    Sponsor Name:Hopital Erasme
    Full Title: Serum pharmacokinetics of Caspofungin in patients with liver failure.
    Medical condition: The patient admitted for alcoholic hepatitis or decompensated cirrhosis (Child-Pugh score of 10-15) presenting with invasive aspergillosis (proven or probable) and treated by caspofungin.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004871 10024678 Liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002079-16 Sponsor Protocol Number: E2013_PK_CASPO70_LIVERFAILURE Start Date*: 2013-09-05
    Sponsor Name:Hospital Erasme
    Full Title: Pharmacokinetics of Caspofungin after one dose in patients with liver failure.
    Medical condition: The pharmacokinetics parameters of caspofungin will be studied for the patient admitted for alcoholic hepatitis or decompensated cirrhosis (Child-Pugh score 7-15).
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004871 10024678 Liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004649-18 Sponsor Protocol Number: 13001 Start Date*: 2014-02-21
    Sponsor Name:Jens Hilligsø
    Full Title: The effect of phrenic nerve block on postoperative shoulder pain in patients for liver resection – a double blinded randomised controlled trial.
    Medical condition: Posteoperative shoulder pain following open liver resection surgery .
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004864 10024717 Liver tumor LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-013870-42 Sponsor Protocol Number: BOOST Start Date*: 2011-10-11
    Sponsor Name:ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI - FONDAZIONE "G. PASCALE"
    Full Title: Sorafenib in the first line treatment of advanced hepatocellular carcinoma with ChildPugh liver function class B. Multicentre phase 3 randomized trial
    Medical condition: advanced hepatocellular carcinoma with ChildPugh liver function class B
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024720 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004245-42 Sponsor Protocol Number: 10078 Start Date*: 2006-09-07
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: PHARMACODYNAMIC STUDY OF ORAL MIRTOSELECT IN PATIENTS WITH SUSPECTED HEPATIC DISEASE
    Medical condition: Patients with operable liver metastases
    Disease: Version SOC Term Classification Code Term Level
    8.1 10024700 Liver metastases LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-002214-17 Sponsor Protocol Number: NL78220.029.21 Start Date*: 2023-04-24
    Sponsor Name:Amsterdam University Medical Centers
    Full Title: COLLISION RELAPSE trial - Recurrent colorectal liver metastases: repeat local treatment +/- neoadjuvantsystemic therapy - a phase III prospective randomized controlled trial
    Medical condition: Recurrent colorectal liver metastases
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10024700 Liver metastases LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-007890-22 Sponsor Protocol Number: 134/07 Start Date*: 2007-10-16
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Prevention of portal vein Thrombosis with anticoagulant therapy in patients with hepatic cirrhosis (Child B and C)
    Medical condition: Pazienti ambulatoriali e ospedalizzati affetti da cirrosi a eziologia virale o non, in classe B o C di Child, e assenza di trombosi portale o spleno-mesenterica
    Disease: Version SOC Term Classification Code Term Level
    6.1 10019641 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005364-27 Sponsor Protocol Number: 12/2007/U/Sper Start Date*: 2007-09-25
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Ultrasonographic characterization of small nodules in cirrhotic patients using contrast media through splancnic infusion
    Medical condition: hepatic cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019641 Hepatic cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
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