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Clinical trials for cardiac surgical procedures

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    261 result(s) found for: cardiac surgical procedures. Displaying page 3 of 14.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2016-003902-14 Sponsor Protocol Number: 16-118 Start Date*: 2017-07-06
    Sponsor Name:RWTH Aachen University, represented by the Clinical Trial Center (CTC-A)
    Full Title: Intravenous Fish Oil based Lipid Emulsion as Pharmaconutrient Strategy in High-Risk Cardiac Surgery Patients: a Phase II Dosing Study
    Medical condition: Given the recently meta-analyzed data from previous RCTs about fish oil , we hypothesize that the provision of intravenous (i.v.) FO (0.20 g/kg and 0.50 g/kg) to cardiac surgery patients may reduc...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001033-24 Sponsor Protocol Number: 1234 Start Date*: 2016-01-25
    Sponsor Name:AOU CITTA' DELLA SALUTE E DELLA SCIENZA DI TORINO
    Full Title: The management of post-operative pain nia patients undergoing cardiac surgery mini - invasive minithoracotomy : Randomized trial
    Medical condition: The management of postoperative pain in patients undergoing cardiac surgery minimally invasive minithoracotomy : randomized
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10043491 Thoracotomy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-004295-28 Sponsor Protocol Number: STER-AMVR-01 Start Date*: 2014-11-14
    Sponsor Name:Oulu University Hospital, Department of Anaesthesia
    Full Title: Postoperative pain management after heart valve surgery using parasternal block and PCA Oxycodone
    Medical condition: Mitral or aortic valve disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10049495 Heart valve operation NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-001795-34 Sponsor Protocol Number: CL-N-HTX-Paed-II/10/20 Start Date*: 2023-01-30
    Sponsor Name:Dr. Franz Köhler Chemie GmbH
    Full Title: A prospective randomized single blind multicenter phase II study of organ perfusion with Custodiol-N compared with Custodiol in heart transplantation in children
    Medical condition: Preservation of hearts prior to heart transplantation in children
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10019314 Heart transplant PT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005440-98 Sponsor Protocol Number: Start Date*: 2012-04-12
    Sponsor Name:AKH Linz
    Full Title: Double blinded randomised trial for the evaluation of the effectiveness of prophylactic use of sildenafil for the prevention of pulmonary hypertensive crisis after congenital heart surgery
    Medical condition: Ventriculs septal defect, atrioventricular canal with pulmonary hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10010401 Congenital cardiovascular anomaly therapeutic procedures HLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003036-12 Sponsor Protocol Number: IFX-1-P2.2 Start Date*: 2016-04-22
    Sponsor Name:InflaRx GmbH
    Full Title: A phase II randomized, placebo-controlled, double-blind, dose-escalation study to evaluate safety, pharmacokinetics and pharmacodynamic dose response relationship of IFX-1 in patients undergoing co...
    Medical condition: Prevention of organ dysfunction induced by inflammatory response after complex cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10063101 Post procedural inflammation PT
    20.0 100000004867 10062357 SIRS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003498-13 Sponsor Protocol Number: HIP/FUSION#1 Start Date*: 2016-03-18
    Sponsor Name:Institut for Klinisk Medicin, Aarhus Universitet
    Full Title: Surgical anesthesia for elective hip surgery - hemodynamic effect of lumbosacral plexus blockade compared to continuous spinal anesthesia
    Medical condition: No specific medical condition is investigated. The objective of the investigation is to compare two methods for surgical anesthesia for total hip replacement.
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10068084 Anesthesia procedure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002671-14 Sponsor Protocol Number: CRAD001ADE14 Start Date*: 2008-02-18
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A 15-month, multi-center, randomized, open-label, parallel group study investigating the renal tolerability, efficacy and safety of a CNI-free regimen (Certican® and MPA) versus a low-dose CNI- reg...
    Medical condition: heart transplantation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10019314 Heart transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-000401-76 Sponsor Protocol Number: 7715 Start Date*: 2019-11-26
    Sponsor Name:University hospital of Montpellier
    Full Title: Transfusion savings in heart surgery: impact of individual strategy, optimized by erythropoietin (EPO) and metabolic adjustment (ScvO2)
    Medical condition: Heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005136-76 Sponsor Protocol Number: ASINC101C Start Date*: 2005-05-02
    Sponsor Name:Professor Christina Eintrei,Institution of Medical & Health, Section of Anesthesiology
    Full Title: Aspirin in noncardiac surgery
    Medical condition: Patients with cardiovascular risk factors undergoing elective non-cardiac surgery of high or intermediate risk.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004399-68 Sponsor Protocol Number: 1925-201-008 Start Date*: 2019-03-29
    Sponsor Name:Allergan Ltd.
    Full Title: A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose Ranging Study to Evaluate the Efficacy and Safety of Botulinum Toxin Type A (AGN 151607) Injections into the Epicardial F...
    Medical condition: Post-operative atrial fibrillation (POAF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) ES (Completed) AT (Completed) SE (Completed) NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-017595-25 Sponsor Protocol Number: 04-AnIt-09/UKM09_0031 Start Date*: 2011-02-22
    Sponsor Name:University Hospital Muenster
    Full Title: Balanced 6 % HES 130/0.4 vs. balanced crystalloid-based infusion in patients undergoing colorectal surgery
    Medical condition: Patients undergoing colorectal surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10040668 Sigmoid hemicolectomy LLT
    14.1 10042613 - Surgical and medical procedures 10009879 Colectomy total PT
    14.1 10042613 - Surgical and medical procedures 10059848 Proctocolectomy PT
    14.1 10042613 - Surgical and medical procedures 10009877 Colectomy NOS LLT
    14.1 10042613 - Surgical and medical procedures 10019460 Hemicolectomy LLT
    14.1 10042613 - Surgical and medical procedures 10039153 Right hemicolectomy LLT
    14.1 10042613 - Surgical and medical procedures 10024107 Left hemicolectomy LLT
    14.1 10042613 - Surgical and medical procedures 10063950 Ileocolectomy PT
    14.1 10042613 - Surgical and medical procedures 10061778 Colectomy PT
    14.1 10042613 - Surgical and medical procedures 10044083 Total colectomy LLT
    14.1 10042613 - Surgical and medical procedures 10009878 Colectomy partial LLT
    14.1 10042613 - Surgical and medical procedures 10063065 Anterior rectum resection LLT
    14.1 10042613 - Surgical and medical procedures 10009880 Colectomy transverse LLT
    14.1 10042613 - Surgical and medical procedures 10033684 Panproctocolectomy LLT
    14.1 10042613 - Surgical and medical procedures 10044447 Transverse colectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003648-31 Sponsor Protocol Number: PKPDHM-001 Start Date*: 2011-11-17
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Pharmacokinetic-pharmacodynamic modeling of the postoperative pain sensation during patient-controlled analgesia with target-controlled infusion of Hydromorphone, taking into account the interactio...
    Medical condition: Pain therapy after elective cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-003714-68 Sponsor Protocol Number: 1744/2017 Start Date*: 2017-11-15
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of Supplemental Oxygen on Perioperative Brain Natriuretic Peptide Concentration in Cardiac Risk Patients - A prospective randomized clinical trial
    Medical condition: Evaluation of the effect of 80% versus 30% supplemental oxygen administration during major abdominal surgery on postoperative brain natriuretic peptide concentration.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10059883 Fraction of inspired oxygen PT
    20.0 100000173317 10050322 Oxygen supplementation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-002126-90 Sponsor Protocol Number: 2019/399/HP Start Date*: 2021-03-09
    Sponsor Name:Direction de la Recherche Clinique et de l’Innovation – CHU de Rouen
    Full Title: Opioid-Free Anesthesia in Cardiac Surgery
    Medical condition: Patients undergoing cardiac surgery under extracorporeal circulation with at least one aorto-coronary bypass and the removal of at least one internal mammary artery
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10066124 Extracorporeal circulation PT
    20.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004657-89 Sponsor Protocol Number: BIOS-16-001 Start Date*: 2020-12-14
    Sponsor Name:Ethicon Inc
    Full Title: A Prospective Study Evaluating the Safety and Effectiveness of EVARREST® Fibrin Sealant Patch in Controlling Mild or Moderate Hepatic Parenchyma or Soft Tissue Bleeding During Open, Abdominal, Retr...
    Medical condition: Mild or moderate hepatic parenchyma or soft tissue bleeding during open, abdominal, retroperitoneal, pelvic and thoracic (non-cardiac) surgery
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-000187-15 Sponsor Protocol Number: MK-8616-145 Start Date*: 2017-09-18
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase 4 Randomized, Active-Comparator Controlled Clinical Trial to Study the Safety of Sugammadex (MK-8616) for the Reversal of Neuromuscular Blockade Induced by Either Rocuronium Bromide or Vecu...
    Medical condition: Reversal of neuromuscular blockade
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10018061 General anesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-002606-39 Sponsor Protocol Number: 20162020 Start Date*: 2016-11-09
    Sponsor Name:Nemocnice Na Homolce
    Full Title: Resurgence in sternotomy fortified by vitamin D supplementation in cardiac surgery
    Medical condition: sternotomy healing
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10051501 Sternotomy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-002248-26 Sponsor Protocol Number: IEOS701/412 Start Date*: 2012-10-16
    Sponsor Name:ISTITUTO EUROPEO DI ONCOLOGIA
    Full Title: Prevention of anthracycline-induced cardiotoxicity: a multicentre randomizedtrial comparing two therapeutic strategies.
    Medical condition: Anthracycline-­‐induced cardiotoxicity
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10008444 Chemotherapy cardiotoxicity attenuation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004446-42 Sponsor Protocol Number: MB11-2018 Start Date*: 2019-06-20
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA S.CROCE E CARLE CUNEO
    Full Title: Maintenance Of aNtiplatElet Therapy in patients with coronary stenting undergoing surgery
    Medical condition: Patients a least 18 years of age on DAPT per standard of care who are planned to undergo non deferrable cardiac and non cardiac surgery which will require discontinuation of a P2Y12 inhibitor. Subj...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10011082 Coronary artery disorders HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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