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Clinical trials for Surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    5,833 result(s) found for: Surgery. Displaying page 4 of 292.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-002175-24 Sponsor Protocol Number: 2014_68 Start Date*: 2015-12-10
    Sponsor Name:Centre Hospitalier Régional et Universitaire de Lille
    Full Title: Effect of the exacyl on perioperative bleeding during surgery of orthognatism of the upper maxillary
    Medical condition: Bleeding during surgery of orthognatism of the upper maxillary
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005596-90 Sponsor Protocol Number: NL51548.100.14 Start Date*: 2015-04-22
    Sponsor Name:St. Lucas Andreas Hospital
    Full Title: Comparison of femoral nerve block with posterior capsule infiltration versus anterior and posterior capsule infiltration after total knee replacement.
    Medical condition: patienst requiring total knee replacement for non-inflammatory osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004501-27 Sponsor Protocol Number: 2183/2019 Start Date*: 2021-01-28
    Sponsor Name:Medical University of Vienna
    Full Title: Perioperative analgesia in children undergoing ophthalmic surgery
    Medical condition: perioperative analgesia
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000548-71 Sponsor Protocol Number: NOK0020 Start Date*: 2021-01-25
    Sponsor Name:Nederlandse Obesitas Kliniek
    Full Title: Liraglutide for low-responders after bariatric surgery
    Medical condition: Morbid obesity
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003088-76 Sponsor Protocol Number: 11-170 Start Date*: 2014-07-14
    Sponsor Name:Clinical Evaluation Research Unit (CERU)
    Full Title: SodiUm SeleniTe Adminstration IN Cardiac Surgery surgery (SUSTAIN CSX®-trial) - A randomized controlled trial of high dose sodium-selenite administration in high risk cardiac surgical patients
    Medical condition: Selenium is a key component of a number of selenoproteins which protect against oxidative stress and is well recognised for its prominent role in immune defence. Selenoproteins have the potential t...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005234-19 Sponsor Protocol Number: Start Date*: 2013-10-08
    Sponsor Name:Blodbanken, Rigshospitalet
    Full Title: The effect of prostacyclin on haemostasis as evaluated by thrombelastography and endothelial markers in patients undergoing major abdominal surgery. A pilot study.
    Medical condition: Capillary leakage secondary to major surgical stress
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-003144-36 Sponsor Protocol Number: NAC.TEP16 Start Date*: 2020-11-18
    Sponsor Name:Radboud University Medical Centre
    Full Title: Pilot study: postoperative pain reduction by pre emptive N-Acetylcysteine
    Medical condition: postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-000145-24 Sponsor Protocol Number: PI2015_843_0001 Start Date*: 2015-09-21
    Sponsor Name:CHU Amiens - Picardie
    Full Title: Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery (CRPS-VITC)
    Medical condition: Algoneurodystrophy CRPS type 1
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004852 10001665 Algoneurodystrophy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-001650-26 Sponsor Protocol Number: ZOL6700 Start Date*: 2019-10-25
    Sponsor Name:Hospital South West Jutland
    Full Title: Zoledronic acid for prevention of bone loss after bariatric surgery
    Medical condition: Morbid obese subjects undergoing bariatric surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003321-32 Sponsor Protocol Number: 108 Start Date*: 2021-01-21
    Sponsor Name:Hvidovre Hospital, Dep. of Orthopaedic Surgery
    Full Title: Evaluation of intra articular Tranexamic acid for reduction of total blood loss in total hip arthroplasty
    Medical condition: The benefit of additional Tranexamic Acid (TXA) injected intra-articular at the end of surgery for patients undergoing a unilateral total hip arthroplasty in addition to conventional IV TXA to redu...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10003397 Arthroplasty of hip LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-005710-34 Sponsor Protocol Number: Acide_Tranexamique Start Date*: 2022-02-21
    Sponsor Name:Polyclinique Jean Villar - Bruges
    Full Title: Benefits on post-operative pain of intraoperative tranexamic acid administration during shoulder arthroscopy.
    Medical condition: Shoulder arthroscopy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004848 10077421 Shoulder arthroscopy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-003617-36 Sponsor Protocol Number: D-PLEX312 Start Date*: 2020-12-13
    Sponsor Name:PolyPid Ltd.
    Full Title: Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to Assess Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care ...
    Medical condition: Prevention of post abdominal surgery incisional infection.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10078408 Surgical site infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Trial now transitioned) PL (Trial now transitioned) DE (Trial now transitioned) IE (Trial now transitioned) PT (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-004399-68 Sponsor Protocol Number: 1925-201-008 Start Date*: 2019-03-29
    Sponsor Name:Allergan Ltd.
    Full Title: A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose Ranging Study to Evaluate the Efficacy and Safety of Botulinum Toxin Type A (AGN 151607) Injections into the Epicardial F...
    Medical condition: Post-operative atrial fibrillation (POAF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) ES (Completed) AT (Completed) SE (Completed) NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-002076-41 Sponsor Protocol Number: 0667 Start Date*: 2018-08-23
    Sponsor Name:University of Leicester
    Full Title: A RANDOMISED CONTROLLED TRIAL OF PRE-SURGERY SODIUM VALPROATE, FOR THE PREVENTION OF ORGAN INJURY IN CARDIAC SURGERY: Val-CARD
    Medical condition: Reduction of myocardial and kidney injury risk of post cardiac surgery by increasing the expression of genes that promote myocardial mitochondrial homeostasis via effects on chromatin histone deace...
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    20.1 100000004849 10057768 Post-cardiac injury syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-002078-38 Sponsor Protocol Number: SU/2016/6033 Start Date*: 2017-12-06
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: Effectiveness, cost effectiveness and safety of gabapentin versus placebo as an adjunct to multimodal pain regimens in surgical patients: A placebo controlled randomised controlled trial with blind...
    Medical condition: Post surgery pain management
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10036237 Post operative analgesia LLT
    20.0 10042613 - Surgical and medical procedures 10056350 Pain management PT
    20.0 100000004863 10036286 Post-operative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-000753-45 Sponsor Protocol Number: NAVIT-18 Start Date*: 2018-11-11
    Sponsor Name:NAVARRBIOMED-FUNDACION MIGUEL SERVET
    Full Title: Vitreretinal surgery with and without oral anticoagulants: surgical complications, visual results and perioperative thromboembolic events.
    Medical condition: Patients undergoing vitreoretinal surgery under treatment with oral anticoagulants
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005916-23 Sponsor Protocol Number: ML39791 Start Date*: 2020-12-18
    Sponsor Name:Genentech, Inc.
    Full Title: A Phase IV, Multicenter, Single-Arm, Open-Label Study of Emicizumab Prophylaxis in Patients With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures
    Medical condition: Hemophilia A with or without inhibitors
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10053753 Hemophilia A without inhibitors LLT
    20.0 10010331 - Congenital, familial and genetic disorders 10053751 Hemophilia A with anti factor VIII LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2015-004424-65 Sponsor Protocol Number: 15085MS-AS Start Date*: 2016-05-09
    Sponsor Name:Belfast Health and Social Care Trust
    Full Title: Prevention of post-operative complications by using HMG-CoA Reductase Inhibitor in patients undergoing oesophagectomy - A multicentre, randomised, double blind, placebo controlled trial
    Medical condition: Post-operative complications - Post-operative Pulmonary complication, Acute Respiratory Distress Syndrome and Myocardial Infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2018-000757-49 Sponsor Protocol Number: QRK309 Start Date*: 2018-12-05
    Sponsor Name:Quark Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Placebo Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of QPI-1002 for the Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for A...
    Medical condition: QPI-1002 is being developed for prevention of acute kidney injury (AKI) in patients at risk for AKI following cardiac surgery and for reduction in the incidence and severity of delayed graft functi...
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) GB (GB - no longer in EU/EEA) BE (Completed) CZ (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-010173-20 Sponsor Protocol Number: A3051113 Start Date*: 2009-08-06
    Sponsor Name:Pfizer Limited, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK
    Full Title: A MULTICENTER, OPEN LABEL STUDY TO INVESTIGATE THE FEASIBILITY AND EFFICACY OF A SMOKING CESSATION PROGRAM WITH VARENICLINE IN PATIENTS UNDERGOING ELECTIVE SURGERY
    Medical condition: Smoking cessation in patients scheduled for elective surgery.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10053325 Smoking cessation therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended) FR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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