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Clinical trials for Glaucoma, Open-Angle

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    147 result(s) found for: Glaucoma, Open-Angle. Displaying page 5 of 8.
    « Previous 1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2012-001247-51 Sponsor Protocol Number: v.1/040312 Start Date*: 2012-06-04
    Sponsor Name:Mika Harju
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10006028 Borderline glaucoma (glaucoma suspect) LLT
    14.1 10015919 - Eye disorders 10037118 Pseudoexfoliation glaucoma LLT
    14.1 10015919 - Eye disorders 10036675 Primary angle-closure glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2010-021507-24 Sponsor Protocol Number: 192024-050 Start Date*: 2011-02-23
    Sponsor Name:Allergan Limited
    Full Title: A Multicenter, Double-masked, Randomized, Parallel Study of the Safety and Efficacy of Bimatoprost 0.03%/Timolol 0.5% Preservative freeOphthalmic Solution Compared with GANFORT® (bimatoprost 0.03%/...
    Medical condition: Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10008833 Chronic angle-closure glaucoma LLT
    14.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    14.0 10015919 - Eye disorders 10009034 Chronic open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) CZ (Completed) GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-000653-22 Sponsor Protocol Number: GART1013 Start Date*: 2006-07-26
    Sponsor Name:Moorfields Eye Hospital
    Full Title: The UK Glaucoma Treatment Study
    Medical condition: Primary open-angle Glaucoma Pseudoexfoliation Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-001489-24 Sponsor Protocol Number: PSt012015 Start Date*: 2015-11-19
    Sponsor Name:Pharma Stulln GmbH
    Full Title: Prospective, controlled, randomized, investigator-masked, mul-ticenter, phase III trial to demonstrate the efficacy and safety of Brimonidine UD
    Medical condition: open angle glaucoma, elevated intraocular pressure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-002252-18 Sponsor Protocol Number: IT-04-03 Start Date*: 2005-09-27
    Sponsor Name:ALCON ITALIA
    Full Title: Hypotonic efficacy and tollerability of Travoprost in patient with glaucoma or ocular hypertension, monotherapy or fixed association beta-blocking not controlled or intollerant.
    Medical condition: Elevated intraocular pressure reduction in patient with ocular hypertension or open-angle glaucoma.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10018307 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-024244-15 Sponsor Protocol Number: RDG-10-251 Start Date*: 2011-07-01
    Sponsor Name:ALCON Research Ltd
    Full Title: "Patient Preference Comparison of Azarga versus Cosopt, in Patients with Open-Angle Glaucoma or Ocular Hypertension."
    Medical condition: Open-Angle Glaucoma and Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-004012-37 Sponsor Protocol Number: HOM1-2015 Start Date*: 2015-12-18
    Sponsor Name:Ordination Dr. Hommer
    Full Title: An open, non-randomized study on the effect of changing from preserved prostaglandin formulations to preservative free tafluprost (Saflutan® Augentropfen) in patients with ocular hypertension or pr...
    Medical condition: Glaucoma / Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    18.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-010834-23 Sponsor Protocol Number: C-09-006 Start Date*: 2009-04-30
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A multi-center, double-masked study of the safety and efficacy of DuoTrav APS compared to DuoTrav in patients with open-angle glaucoma or ocular hypertension
    Medical condition: Open-angle glaucoma (with or without pseudoexfoliation or pigment dispersion component) or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-006718-10 Sponsor Protocol Number: Alcon SMA-08-16 Start Date*: 2009-08-17
    Sponsor Name:Alcon Laboratories, Inc.
    Full Title: The Efficacy and Safety of Travoprost 0.004% versus Tafluprost 0.005% in Primary Open-Angle Glaucoma or Ocular Hypertensive Patients.
    Medical condition: primary open-angle glaucoma ocular hypertension pigment dispersion glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-004946-13 Sponsor Protocol Number: IIS40942 Start Date*: 2013-09-30
    Sponsor Name:University Hospitals Leuven
    Full Title: Impact of timolol/dorzolamide therapy on autoregulation in glaucoma patients
    Medical condition: Primary open-angle glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000811-27 Sponsor Protocol Number: Gl-HG-szem1-07-001 Start Date*: 2007-05-09
    Sponsor Name:Department of Ophthalmology, SEmmelweis University
    Full Title: Evaluation of additional intraocular pressure reduction with once daily, evening administration of travoprost 0.004%, once daily, evening administration of travoprost 0.004%/timolol 0.5% fixed comb...
    Medical condition: Open-angle glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004543-30 Sponsor Protocol Number: A6111137 Start Date*: 2008-11-24
    Sponsor Name:Pfizer Inc. 235 East 42nd Street, NEW YORK, NY 10017. US
    Full Title: A PHASE 3 PROSPECTIVE, RANDOMIZED, DOUBLE MASKED, 12 WEEK, PARALLEL GROUP STUDY EVALUATING THE EFFICACY AND SAFETY OF LATANOPROST AND TIMOLOL IN PAEDIATRIC SUBJECTS WITH GLAUCOMA
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010486 Congenital glaucoma LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) IT (Completed) SI (Completed) BE (Completed) PT (Completed) FR (Completed) CZ (Completed) SK (Completed) DK (Prematurely Ended) GR (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2013-003157-16 Sponsor Protocol Number: OPHT-260213 Start Date*: 2013-08-27
    Sponsor Name:Ordination Dr. Hommer
    Full Title: An open, non-randomized study on the effect of preservative free tafluprost (Saflutan® Augentropfen) in patients with ocular hypertension or with primary open angle glaucoma with an uncontrolled in...
    Medical condition: Glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-002281-31 Sponsor Protocol Number: Piromelatine-IOP1 Start Date*: 2016-09-19
    Sponsor Name:Neurim Pharmaceuticals (1991) Ltd.
    Full Title: A randomized, double-blind, placebo-controlled, study of oral treatment of piromelatine in patients with ocular hypertension (OHT) or primary open angle glaucoma (POAG).
    Medical condition: ocular hypertension primary open angle glaucoma
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2015-005314-29 Sponsor Protocol Number: QTM/OMN-0115 Start Date*: 2016-03-02
    Sponsor Name:OMNIVISION GmbH
    Full Title: Randomized, open-label, two parallel group clinical trial, conducted under blinding evaluator conditions to compare the efficacy and tolerability of preservative-free formulation of Latanoprost 50µ...
    Medical condition: Open Angle Glaucoma or Ocular Hypertension
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019975-30 Sponsor Protocol Number: 35131 Start Date*: 2010-08-24
    Sponsor Name:University Medical Center, Johannes Gutenberg-University Mainz
    Full Title: Investigation of the efficacy and safety of preoperative IOP reduction with preservative-free COSOPT-S® (dorzolamide/timolol, MSD) eye drops versus oral acetazolamide and dexamethasone eye drops an...
    Medical condition: Patients with glaucoma requiring trabeculectomy (filtration surgery)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10018304 Glaucoma LLT
    12.1 10050156 Glaucoma surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001680-30 Sponsor Protocol Number: 529 Start Date*: 2007-11-02
    Sponsor Name:Bausch&Lomb Dr Gerhard Mann chem.-Fabrik GmbH
    Full Title: Randomized parallel-group, multicentre study to evaluate the after-use sensation and safety of carteolol LA 2% versus timolol LA 0.5% in simple intra-ocular hypertension and glaucoma.
    Medical condition: Adult patients suffering from unilateral or bilateral ocular hypertension or POAG, IOP controlled with beta-blocker monotherapy (IOP < 21 mmHg and visual field stable)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) PT (Completed) BE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2015-005540-34 Sponsor Protocol Number: CLR_14_12 Start Date*: 2016-07-19
    Sponsor Name:Sun Pharma Advanced Research Company, Ltd. (SPARC)
    Full Title: A Multi-Center, Investigator-Masked, Randomized, Crossover, Equivalence Study of the Safety and Efficacy of Once Daily Brimonidine Tartrate 0.35% Ophthalmic Suspension Compared with Brimonidine Tar...
    Medical condition: Open-angle glaucoma, chronic angle closure glaucoma with patent iridotomy, pseudoexfoliation, pigment dispersion, or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    19.1 10015919 - Eye disorders 10018304 Glaucoma PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2009-012799-28 Sponsor Protocol Number: MAF-AGN-OPH-GLA-010 Start Date*: 2009-11-11
    Sponsor Name:Allergan
    Full Title: Estudio Piloto de tres meses, multicéntrico, enmascarado para el Investigador, para evaluar la eficacia y la seguridad de una combinación fija de Bimatoprost/Timolol versus Latanoprost en pacientes...
    Medical condition: Treatment-Naïve Patients with Open Angle Glaucoma at High Risk of Glaucomatous Progression. Pacientes Naïve con glaucoma de ángulo abierto con alto riesgo de progresión glaucomatosa.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2008-004763-19 Sponsor Protocol Number: FARM7CZ54W Start Date*: 2009-06-03
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: EFFICACY AND SAFETY OF TOPICALLY APPLIED PROSTAGLANDIN ANALOGUE AND CARBONIC ANHYDRASE INHIBITOR FOR THE TREATMENT OF PAEDIATRIC GLAUCOMA REFRACTORY TO SURGICAL PROCEDURES
    Medical condition: Children affected to primary Paediatric Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064033 Infantile glaucoma LLT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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