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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,347 result(s) found. Displaying page 549 of 2,218.
    «« First « Previous 545  546  547  548  549  550  551  552  553  Next» Last»»
    EudraCT Number: 2007-007156-33 Sponsor Protocol Number: CRO970 (MIND) Start Date*: 2008-05-23
    Sponsor Name:Imperial College
    Full Title: Melatonin As A Novel Neuroprotectant in Preterm Infants- Dosage study
    Medical condition: Brain Injury in Preterm Infants
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013384 Disorders relating to short gestation and unspecified low birthweight LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-007168-94 Sponsor Protocol Number: HD0607 Start Date*: 2008-06-20
    Sponsor Name:AZIENDA OSPEDALIERA "S. CROCE E CARLE"
    Full Title: PHASE II MULTICENTRE CLINICAL STUDY WITH EARLY TREATMENT INTENSIFICATION IN PTS WITH HIGH-RISK HODGKIN LYMPHOMA, IDENTIFIED AS FDG-PET SCAN POSITIVE AFTER TWO CONVENTIONAL ABVD COURSES
    Medical condition: HD ADVANCED DISEASE
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025319 Lymphomas Hodgkin's disease HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004613-34 Sponsor Protocol Number: NordLOTS protocol 1.4 Start Date*: 2008-03-14
    Sponsor Name:The Centre for Child and Adolescent Mental Health, Eastern and Southern Norway (R.BUP)
    Full Title: Nordic Longterm OCD treatment Study: A Nordic Multicenter treatment study evaluating a stepped care model based on the "Expert Clinical Guidelines". The study is performed with no sponsor from phar...
    Medical condition: Obsessive Compulsive Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049596 Obsession LLT
    9.1 10010219 Compulsions LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005101-29 Sponsor Protocol Number: KCH-MDS-04-1.0 Start Date*: 2005-02-24
    Sponsor Name:King's College Hospital NHS Foundation Trust [...]
    1. King's College Hospital NHS Foundation Trust
    2. King's College London
    Full Title: THE EFFICACY AND SAFETY OF LENALIDOMIDE (Revlimid®) MONOTHERAPY IN RED BLOOD CELL TRANSFUSION DEPENDENT SUBJECTS WITH MYELODYSPLASTIC SYNDROME ASSOCIATED WITH A DEL (5q) CYTOGENETIC ABNORMALITY
    Medical condition: Myelodysplastic Syndrome (MDS) associated with a Del (5q) cytogenetic abnormality
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004864 10067097 5q minus MDS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-005106-79 Sponsor Protocol Number: ST1481-DM02-008 Start Date*: 2005-02-01
    Sponsor Name:Sigma Tau industrie Farmaceutiche Riunite Spa
    Full Title: Phase II study of gimatecan (ST 1481) as salvage treatment in patients with advanced breast cancer after anthracycline /taxanes-based chemotherapy regimen
    Medical condition: advanced breast cancer
    Disease: Version SOC Term Classification Code Term Level
    10006285 LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005115-29 Sponsor Protocol Number: RA1104046 Start Date*: 2005-06-24
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A randomised, placebo-controlled, parallel group single dose study of SB681323 in patients with active RA to investigate the CRP dose response relationship
    Medical condition: Rheumatoid arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006443-50 Sponsor Protocol Number: AGO/2007/013 Start Date*: 2007-12-12
    Sponsor Name:University Hospital Ghent
    Full Title: Prospective, randomized trial to evaluate the administration of 2 different doses of recombinant FSH to patients with age depended insufficient ovarian response during IVF/ICSI
    Medical condition: Patients with age dependend insufficient ovarian response during IVF/ICSI
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006445-41 Sponsor Protocol Number: CTSSTS1010207V2 Start Date*: 2012-01-28
    Sponsor Name:HEALTH RICERCAE SVILUPPO SRL
    Full Title: The irreversibility of hemorrhagic shock treatment with anti-opiod neuropeptide
    Medical condition: Mortality of hemorrhagic shock grade 2 and 3 is from 50 to '80% in the first 24 hours, and morbidity and mortality betrayed is to 7 to 8 days of' 90% for Acute Respiratory Distress Syndrome and / o...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10049771 Shock haemorrhagic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001937-17 Sponsor Protocol Number: SP879 Start Date*: 2006-08-22
    Sponsor Name:Schwarz Biosciences GmbH
    Full Title: A randomized, double-blind, placebo-controlled, parallel-group proof-of-concept trial to assess the efficacy, safety and tolerability of ascending doses of rotigotine nasal spray for the acute trea...
    Medical condition: idiopathic Restless Leg's Syndrome
    Disease: Version SOC Term Classification Code Term Level
    8.1 10058920 Restless legs syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005744-92 Sponsor Protocol Number: 2006/101/HP Start Date*: 2007-05-09
    Sponsor Name:CHU - Hôpitaux de Rouen
    Full Title: Evaluation de l'efficacité et de la tolérance d'un anticorps monoclonal anti-CD20 : Rituximab (Mabthera(R)) dans le traitement des rechutes de pemphigoïde bulleuse
    Medical condition: Pemphigoïde bulleuse
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005531-28 Sponsor Protocol Number: Urso in Obese Start Date*: 2008-04-03
    Sponsor Name:Hanns-Ulrich Marschall
    Full Title: Ursodeoxycholic Acid in Morbidly Obese Patients Before Bariatric Surgery
    Medical condition: Patients with morbid obesity (MB) are investigated. MB is very frequently (90%) associated with non-alcoholic fatty liver disease (NAFLD) comprising a spectrum reaching from steatosis (NAFL) over s...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029530 Non-alcoholic fatty liver LLT
    Population Age: Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005540-24 Sponsor Protocol Number: TTCC-2007-01 Start Date*: 2008-03-28
    Sponsor Name:Grupo Español de Tratamiento de los Tumores de Cabeza y Cuello (TTCC)
    Full Title: Ensayo clínico fase III aleatorizado, multicéntrico, de quimioterapia de inducción con la combinación docetaxel, cisplatino y 5-fluorouracilo (TPF) seguido de tratamiento concomitante con Cisplatin...
    Medical condition: Carcinoma escamoso de cabeza y cuello localmente avanzado, no resecable.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007473 Carcinoma squamous LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-005547-17 Sponsor Protocol Number: RHMNUT0048 Start Date*: 2010-01-28
    Sponsor Name:Southampton University Hospital NHS Trust
    Full Title: Refeeding risks in patients requiring nutrition support. A twin centre double-blind randomised controlled trial of parenteral nutrition support.
    Medical condition: Patients who have a non-functioning gastrointestinal tract require artifical intravenous nutrition. This is usally a result recent surgery or sepsis causing a reversible short term paralysis of th...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-005549-39 Sponsor Protocol Number: EHT 0202/002 Start Date*: 2007-12-19
    Sponsor Name:EXONHIT
    Full Title: A pilot, randomized, double-blind, placebo-controlled, parallel group, multicentre, phase IIa study to determine the clinical safety/tolerability and exploratory efficacy of EHT 0202 (40 and 80 mg ...
    Medical condition: Alzheimer disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005976-15 Sponsor Protocol Number: CCR3024 Start Date*: 2008-03-27
    Sponsor Name:Royal Marsden Hospital NHS Trust
    Full Title: A randomised open-labelled multicentre trial of the efficacy of epirubicin, oxaliplatin and capecitabine (EOX) with or without panitumumab in previously untreated advanced oesophago-gastric cancer ...
    Medical condition: Advanced (Inoperable locally advanced, metastatic or recurrent) , histologically verified adenocarcinoma or undifferentiated carcinoma of the oesophagus, oesophagogastric junction or stomach.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017770 Gastric carcinoma LLT
    9.1 10030155 Oesophageal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006072-11 Sponsor Protocol Number: CASA404A2301 Start Date*: 2008-05-08
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A Phase III, randomized, double-blind, placebo-controlled multi-center study of ASA404 in combination with paclitaxel and carboplatin as first-line treatment for locally advanced or metastatic (sta...
    Medical condition: This phase III trials is conducted world-wide in order to demonstrate safety and efficacy of ASA404 in combination with a paclitaxel-carboplatin chemotherapy in the treatment of patients with stage...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066490 Progression of non small cell lung cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Prematurely Ended) ES (Completed) CZ (Prematurely Ended) DE (Prematurely Ended) NL (Prematurely Ended) IT (Prematurely Ended) HU (Completed) FR (Completed) SE (Prematurely Ended) PL (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2007-006994-10 Sponsor Protocol Number: SEQ-ALO-2007-01 Start Date*: 2009-02-04
    Sponsor Name:Fundación Investigación Biomédica Hospital Príncipe de Asturias
    Full Title: Evaluación de la utilidad del alopurinol en la prevención de la morbimortalidad cardiovascular de los pacientes con enfermedad renal crónica (ERC) e hiperuricemia EVALUATION OF THE USE OF ALLOPURI...
    Medical condition: Enfermedad renal crónica (ERC) e hiperuricemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020907 Hyperuricemia LLT
    9.1 10009119 Chronic renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-007013-37 Sponsor Protocol Number: O3-Hernia-EC07/90024 Start Date*: 2008-04-01
    Sponsor Name:Bernardino Clavo - Hospital Dr. Negrin
    Full Title: Ensayo Clínico aleatorizado del efecto de la Ozonoterapia en el tratamiento de la hernia de disco candidata a cirugía.
    Medical condition: Hernia de disco candidata a cirugia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007056-33 Sponsor Protocol Number: FL2008 RCHOPGM Start Date*: 2008-09-19
    Sponsor Name:Goelams
    Full Title: An open label, multicenter, non randomized phase II study to evaluate anti-tumor efficacy and safety of GM-CSF (sargramostim, Leukine®) associated with RCHOP chemotherapy and Rituximab (MabThera®) ...
    Medical condition: This study evaluate anti-tumor efficacy and safety of GM-CSF (sargramostim, Leukine®) associated with Rituximab (MabThera®) and chemotherapy (CHOP) in patients with non bulky follicular non Hodgkin...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025310 Lymphoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003458-81 Sponsor Protocol Number: GOLF-IG2 Start Date*: 2005-06-28
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: A randomized phase III trial on first line metastatic colorectal carcinoma GOLFIG gemcitabine FOLFOX-4 GM-CSF and interleukin 2 chemo-immunotherapy vs standard FOLFOX-4 chemotherapy
    Medical condition: CHEMIO-IMMUNOTHERAPY IN ADVANCED COLON-CANCER
    Disease: Version SOC Term Classification Code Term Level
    10061451 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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