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Clinical trials for Neuropathic pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    287 result(s) found for: Neuropathic pain. Displaying page 6 of 15.
    EudraCT Number: 2006-002286-40 Sponsor Protocol Number: 1-1 Start Date*: 2006-12-05
    Sponsor Name:Pfizer bv
    Full Title: Chronic Pain Management after Herniorraphy Pregabaline versus Placebo
    Medical condition: Patients suffering from chronic pain of neuropathic character after open hernia repair.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002240-24 Sponsor Protocol Number: 214868-007 Start Date*: 2013-02-28
    Sponsor Name:Allergan Ltd.
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of the Safety and Efficacy of a Single Treatment of AGN-214868 in Patients With Postherpetic Neuralgia
    Medical condition: Postherpetic Neuralgia
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) AT (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003230-42 Sponsor Protocol Number: F13640GE210 Start Date*: 2007-10-08
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: Study of the analgesic effects of repeated doses of F13640 in spinal cord injury patients with moderate to severe central neuropathic pain. A multinational, multicenter, randomized, double blind, p...
    Medical condition: Central neuropathic pain due to spinal cord injury, based on clinical history, clinical examination and appropriate assessment of patient’s signs and symptoms, according to the International Associ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064012 Central pain syndrome LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed) FI (Prematurely Ended) ES (Completed) BE (Completed) IT (Prematurely Ended) NL (Prematurely Ended) HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004792-13 Sponsor Protocol Number: NFX88-2A-2018 Start Date*: 2019-05-23
    Sponsor Name:Neurofix S.L.
    Full Title: A randomized, double-blind, placebo controlled, parallel group, multicentric, phase IIa clinical trial to evaluate the safety, tolerability and therapeutic efficacy of daily oral treatment with NF...
    Medical condition: Neuropathic pain in spinal cord injury patients.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-001598-10 Sponsor Protocol Number: GWDN0603 Start Date*: 2006-09-26
    Sponsor Name:GW Pharma Ltd
    Full Title: A double blind, randomised, placebo controlled, parallel group study of Sativex® in the treatment of subjects with pain due to diabetic neuropathy
    Medical condition: Diabetic Neuropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-000521-31 Sponsor Protocol Number: PI12_01813 Start Date*: 2013-12-26
    Sponsor Name:Gerencia de Atención Primaria de Mallorca
    Full Title: Efficacy and safety of gabapentin versus placebo to prevent the incidence of PostHerpetic Neuralgia
    Medical condition: Postherpetic Neuralgia
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-012836-33 Sponsor Protocol Number: KIP113049 Start Date*: 2009-11-26
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A randomised, double blind study to evaluate the safety and efficacy of the p38 kinase inhibitor, GW856553, in subjects with neuropathic pain from lumbosacral radiculopathy
    Medical condition: Neuropathic pain from lumbosacral radiculopathy
    Disease: Version SOC Term Classification Code Term Level
    12.0 10037779 Radiculopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) DK (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2014-005656-26 Sponsor Protocol Number: 51748.094.15 Start Date*: 2015-10-14
    Sponsor Name:Westfriesgasthuis
    Full Title: Amitriptyline 10% and ketamine 10% cream in neuropathic pain: A randomised, double-blind, placebo-controlled cross-over pilot study with a three months open follow-up
    Medical condition: Patients with peripheral neuropathic pain or scar pain
    Disease: Version SOC Term Classification Code Term Level
    17.1 10040785 - Skin and subcutaneous tissue disorders 10049002 Scar pain PT
    17.1 100000004852 10029181 Nerve pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002948-10 Sponsor Protocol Number: A0081007 Start Date*: 2005-07-14
    Sponsor Name:Pfizer AB
    Full Title: A Randomised Placebo-Controlled Trial of the Efficacy and Safety of Pregabalin in the Treatment of Subjects with Neuropathic Pain Associated with Lumbo-sacral Radiculopathy (protocol dates 2004-11...
    Medical condition: Pain associated with lumbo-sacral radiculopathy
    Disease: Version SOC Term Classification Code Term Level
    7.0 10050085 VTc
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-003968-31 Sponsor Protocol Number: Start Date*: 2014-04-09
    Sponsor Name:University of Edinburgh (ACCORD) [...]
    1. University of Edinburgh (ACCORD)
    2. NHS Lothian (ACCORD)
    Full Title: A phase II RCT of topical menthol gel versus placebo in the treatment of chemotherapy induced peripheral neuropathic pain
    Medical condition: Chemotherapy Induced Peripheral Neuropathy (CIPN)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10040039 Sensory peripheral neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2008-008753-33 Sponsor Protocol Number: CARISNPP2003 Start Date*: 2009-04-23
    Sponsor Name:Janssen Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo- and Active-Controlled Study of Carisbamate in the Treatment of Neuropathic Pain in Diabetic Peripheral Neuropathy Followed by a Blinded Extension Phase
    Medical condition: Neuropathic Pain in Diabetic Peripheral Neuropathy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) ES (Prematurely Ended) FR (Completed) PT (Prematurely Ended) BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002302-43 Sponsor Protocol Number: CHDR1209 Start Date*: 2012-06-08
    Sponsor Name:Dr. Reddy's Laboratories Ltd.
    Full Title: A study to investigate the analgesic effects of buprenorphine and milnacipram in healthy volunteers.
    Medical condition: Pain therapeutics, neuropathic pain, nociceptive pain, synergism between opioids and TCA.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10054095 Neuropathic pain LLT
    14.1 10018065 - General disorders and administration site conditions 10066714 Acute pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-001404-40 Sponsor Protocol Number: KF9906/02 Start Date*: 2005-09-02
    Sponsor Name:Grünenthal GmbH
    Full Title: Cross-over multiple dose study assessing the analgesic efficacy and safety of oral GRT9906 PR compared to active comparator and placebo in subjects with painful polyneuropathy of mixed origin
    Medical condition: Polyneuropathic pain
    Disease: Version SOC Term Classification Code Term Level
    8.0 10054095 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001340-25 Sponsor Protocol Number: UMC-NMZ-EPHENE2020 Start Date*: 2020-07-17
    Sponsor Name:University Medical Center Utrecht
    Full Title: Enrichment randomized double-blind, placebo-controlled cross-over trial with PHEnytoin cream in patients with painful chronic idiopathic axonal polyNEuropathy
    Medical condition: Painful chronic idiopathic axonal polyneuropathy
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10040040 Sensory polyneuropathy axonal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001165-33 Sponsor Protocol Number: ML2676 Start Date*: 2005-04-26
    Sponsor Name:Bart Morlion
    Full Title: A prospective, open randomized, parallel group trial to compare the efficacy and safety of transdermal buprenorphine (Transtec) with gabapentin (Neurontin) in patients with neuropatic pain syndromes
    Medical condition: Neuropathic pain
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-007978-38 Sponsor Protocol Number: V3381-2DPNP-02 Start Date*: 2009-02-12
    Sponsor Name:Vernalis (R & D) Limited
    Full Title: A Randomised, Double-Blind, Placebo-Controlled, Multicentre, Parallel Group Study of the Safety, Tolerability and Efficacy of V3381 for Up to 13 Weeks in Patients with Diabetic Peripheral Neuropath...
    Medical condition: Diabetic Peripheral Neuropathic Pain (DPNP)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012683 Diabetic peripheral neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001587-30 Sponsor Protocol Number: GU11SU387 Start Date*: 2013-09-26
    Sponsor Name:NHS Greater Glasgow and Clyde
    Full Title: The role of pre-emptive analgesia with Qutenza (topical capsaicin 8%) in preventing neuropathic pain following lower limb amputation: a pilot randomised controlled study
    Medical condition: Chronic neuropathic pain following limb amputation
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029205 - Nervous system disorders 10054095 Neuropathic pain LLT
    16.0 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-000210-11 Sponsor Protocol Number: TMP-0315-2018 Start Date*: 2019-09-18
    Sponsor Name:Fraunhofer Gesellschaft for its Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
    Full Title: Prevention of Paclitaxel-induced neuropathic pain by Telmisartan in patients with planned Paclitaxel chemotherapy due to ovarian or breast cancer (PrevTel)
    Medical condition: patients with planned Paclitaxel chemotherapy due to ovarian or breast cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10077974 Peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003197-57 Sponsor Protocol Number: A0081181 Start Date*: 2012-11-09
    Sponsor Name:Pfizer Worldwide Research and Development
    Full Title: A MULTIPLE DOSE PHARMACOKINETIC OPEN-LABEL STUDY OF PREGABALIN (LYRICA) IN HEALTHY LACTATING WOMEN
    Medical condition: neuropathic pain associated with diabetic peripheral neuropathy postherpetic neuralgia neuropathic pain related to spinal cord injury (US), fibromyalgia (US, JP) treatment of central and periphe...
    Disease: Version SOC Term Classification Code Term Level
    15.1 10029205 - Nervous system disorders 10028005 Motor peripheral neuropathy LLT
    15.1 10029205 - Nervous system disorders 10054095 Neuropathic pain LLT
    15.1 10029205 - Nervous system disorders 10036376 Post herpetic neuralgia PT
    15.1 10029205 - Nervous system disorders 10067547 Diabetic peripheral neuropathic pain LLT
    15.1 10022117 - Injury, poisoning and procedural complications 10041552 Spinal cord injury PT
    15.1 10037175 - Psychiatric disorders 10018075 Generalised anxiety disorder PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005344-17 Sponsor Protocol Number: CBDV_2014 Start Date*: 2015-08-21
    Sponsor Name:Department of Anesthesiology and Operative Intensive Care Medicine, Charité (CBF)
    Full Title: Oral cannabidivarin (CBDV) solution for treatment of HIV-associated neuropathic pain – a randomized, double-blind, placebo-controlled phase II study.
    Medical condition: Chronic painful HIV-associated neuropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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