- Trials with a EudraCT protocol (1,699)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
1,699 result(s) found for: Chemistry.
Displaying page 75 of 85.
| EudraCT Number: 2020-001244-26 | Sponsor Protocol Number: COV-2-SOLNATIDE-20 | Start Date*: 2020-04-11 | ||||||||||||||||
| Sponsor Name:Department of Clinical Pharmacology, Medical University of Vienna, Vienna Austria | ||||||||||||||||||
| Full Title: COVID-19: Efficacy of solnatide to treat pulmonary permeability oedema in SARS-Cov-2 positive patients with moderate-to-severe ARDS - a pilot-trial. | ||||||||||||||||||
| Medical condition: Pulmonary permeability oedema in SARS-Cov-2 positive patients with moderate-to-severe ARDS | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: AT (Prematurely Ended) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2021-000685-15 | Sponsor Protocol Number: AXA1125-101 | Start Date*: 2021-10-18 | |||||||||||
| Sponsor Name:Axcella Health, Inc. | |||||||||||||
| Full Title: A Randomized, Double-Blind, Placebo-Controlled, Dose Ranging Study to Evaluate the Safety, Tolerability, and Efficacy of AXA1125 in Subjects With Non Cirrhotic, Non Alcoholic Steatohepatitis and Fi... | |||||||||||||
| Medical condition: Noncirrhotic, Nonalcoholic Steatohepatitis and Fibrosis | |||||||||||||
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| Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: PL (Prematurely Ended) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2020-003210-13 | Sponsor Protocol Number: LYT-100-2020-02 | Start Date*: 2020-10-27 | |||||||||||
| Sponsor Name:PureTech LYT 100, Inc. | |||||||||||||
| Full Title: A Phase 2 Randomized, Double-blind, Placebo-controlled Trial and Open Label Extension to Evaluate the Safety and Efficacy of Deupirfenidone (LYT- 100) in Post-acute COVID-19 Respiratory Disease | |||||||||||||
| Medical condition: COVID-19 respiratory disease | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: RO (Ongoing) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2019-003315-60 | Sponsor Protocol Number: A201 | Start Date*: 2020-11-10 | |||||||||||
| Sponsor Name:Criceto IKM B.V. | |||||||||||||
| Full Title: A phase 1/2 study investigating the pharmacokinetics, safety and efficacy of a highly concentrated buccal formulation of apomorphine (APORON®) in subjects with Parkinson's Disease | |||||||||||||
| Medical condition: Parkinson's Disease | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: NL (Prematurely Ended) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2019-004429-26 | Sponsor Protocol Number: CMP0119 | Start Date*: 2020-05-08 | |||||||||||
| Sponsor Name:PRZEDSIEBIORSTWO FARMACEUTYCZNE LEK-AM SPÓŁKA Z OGRANICZONA ODPOWIEDZIALNOSCIA | |||||||||||||
| Full Title: A multicentre, randomized, open-label, cross-over equivalence study to compare the pharmacodynamic properties, safety, and tolerability of a new combination dry powder of fluticasone propionate and... | |||||||||||||
| Medical condition: asthma | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: PL (Prematurely Ended) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2020-002911-23 | Sponsor Protocol Number: DS102A-08-CV2 | Start Date*: 2020-10-12 | ||||||||||||||||
| Sponsor Name:Afimmune | ||||||||||||||||||
| Full Title: A Randomised, Double-Blind, Placebo-Controlled, Exploratory Phase IIa Study to Assess the Mechanism of Action and Safety of Orally Administered Epeleuton in Patients with Type 2 Diabetes and Diabet... | ||||||||||||||||||
| Medical condition: Type 2 diabetes and diabetic complications | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DE (Completed) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2020-002641-42 | Sponsor Protocol Number: C4591001 | Start Date*: 2020-09-04 | |||||||||||
| Sponsor Name:BioNTech SE | |||||||||||||
| Full Title: A PHASE 1/2/3, PLACEBO-CONTROLLED, RANDOMIZED, OBSERVER-BLIND, DOSE-FINDING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, IMMUNOGENICITY, AND EFFICACY OF SARS-COV-2 RNA VACCINE CANDIDATES AGAINST COV... | |||||||||||||
| Medical condition: Protection against COVID-19 | |||||||||||||
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| Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: DE (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2020-000763-23 | Sponsor Protocol Number: ANJ900D3501 | Start Date*: 2021-12-28 | |||||||||||
| Sponsor Name:Anji Pharma (US) LLC | |||||||||||||
| Full Title: A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo- and Comparator-Controlled Study to Compare the Glycemic Effects, Safety, and Tolerability of Metformin Hydrochloride Delayed-Releas... | |||||||||||||
| Medical condition: Type 2 Diabetes Mellitus with varying renal function from normal up to CKD3B | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: ES (Ongoing) PL (Completed) BG (Completed) HU (Completed) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2022-001631-82 | Sponsor Protocol Number: EDP2939-101 | Start Date*: 2022-11-29 | |||||||||||
| Sponsor Name:Evelo Biosciences, Inc. | |||||||||||||
| Full Title: A Phase 1/2, randomised, placebo-controlled study of EDP2939 in healthy volunteers and participants with moderate plaque psoriasis. | |||||||||||||
| Medical condition: Moderate plaque psoriasis | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: PL (Completed) BG (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2016-001930-93 | Sponsor Protocol Number: GC-627-04 | Start Date*: 2017-01-13 | ||||||||||||||||
| Sponsor Name:Generon (Shanghai) Corporation Ltd. | ||||||||||||||||||
| Full Title: A Phase III, Randomized, Multi-Centre, Double-Blind, Placebo Controlled Clinical Trial of F-627 in Women with Breast Cancer Receiving Myelotoxic Chemotherapy | ||||||||||||||||||
| Medical condition: Women, between 18 and 75 years of age that have been diagnosed with Stage II-IV breast cancer in the adjuvant or metastatic setting and are scheduled to undergo chemotherapy. This is a profilaxis ... | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Female | |||||||||||||||||
| Trial protocol: HU (Completed) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2017-002026-20 | Sponsor Protocol Number: CT7001-001 | Start Date*: 2017-10-31 |
| Sponsor Name:Carrick Therapeutics | ||
| Full Title: A Modular, Multipart, Multiarm, Open-label, Phase I/IIa Study to Evaluate the Safety and Tolerability of CT7001 Alone and in Combination with Anti-cancer Treatments in Patients with Advanced Malign... | ||
| Medical condition: Module 1A: All solid malignancies Module 1B: Solid malignancies, potentially including TNBC, SCLC, CRPC, ovarian cancer patients, and other appropriate cancer indications. Module 1B-1 (TNBC):... | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: GB (GB - no longer in EU/EEA) | ||
| Trial results: View results | ||
| EudraCT Number: 2020-003956-34 | Sponsor Protocol Number: 73763989PAHPB2006 | Start Date*: 2021-01-16 | |||||||||||
| Sponsor Name:Janssen-Cilag International NV | |||||||||||||
| Full Title: A Phase 2, Open-label, Single-arm, Multicenter Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of Treatment With JNJ-73763989, JNJ-56136379, Nucleos(t)ide Analogs, and Pegylate... | |||||||||||||
| Medical condition: Chronic Hepatitis B Virus Infection | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: PL (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2018-002652-33 | Sponsor Protocol Number: T-Haplo-for-SCD | Start Date*: Information not available in EudraCT | |||||||||||
| Sponsor Name:University Hospital of Regensburg | |||||||||||||
| Full Title: A phase 2 trial to assess haploidentical Alpha/ß T-depleted stem cell transplantation in patients with sickle cell disease with no available sibling donor | |||||||||||||
| Medical condition: Sickle Cell Disease | |||||||||||||
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| Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
| Trial protocol: DE (Ongoing) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2019-003064-50 | Sponsor Protocol Number: HLX10-004-NSCLC303 | Start Date*: 2020-06-17 | |||||||||||
| Sponsor Name:Shanghai Henlius Biotech, Inc. | |||||||||||||
| Full Title: A Randomized, Double-Blind, Multicenter, Phase III Clinical Study of HLX10 (Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection) + Chemotherapy (Carboplatin-Nanoparticle Albumin-Bound (na... | |||||||||||||
| Medical condition: First-Line Therapy for Locally Advanced or Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC) | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: PL (Completed) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2013-005406-54 | Sponsor Protocol Number: M14TIL | Start Date*: 2014-05-09 | ||||||||||||||||
| Sponsor Name:Antoni van Leeuwenhoek ziekenhuis | ||||||||||||||||||
| Full Title: Randomized phase III study comparing a non-myeloablative lymphocyte depleting regimen of chemotherapy followed by infusion of tumor infiltrating lymphocytes and interleukin-2 to standard ipilimumab... | ||||||||||||||||||
| Medical condition: Patients with unresectable and metastatic (stage IIIc and stage IV) melanoma will be randomized to either treatment arm A (ipilimumab) or treatment arm B (TIL) after metastasectomy and feasibility ... | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DK (Completed) NL (Completed) | ||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||
| EudraCT Number: 2022-000060-22 | Sponsor Protocol Number: 2020/0424/HP | Start Date*: 2023-04-03 | |||||||||||||||||||||
| Sponsor Name:CHU de Rouen | |||||||||||||||||||||||
| Full Title: Comparison of a personalized maintenance therapy based on the evolution of anti-desmoglein antibodies as biomarkers of pemphigus subclinical activity, with the standard treatment (rituximab + corti... | |||||||||||||||||||||||
| Medical condition: Pemphigus diseases (Pemphigus Vulgaris - PV and Pemphigus Foliaceus (PF). | |||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
| Trial protocol: FR (Trial now transitioned) | |||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||
| EudraCT Number: 2018-005027-16 | Sponsor Protocol Number: NOA-18 | Start Date*: 2020-09-16 | ||||||||||||||||
| Sponsor Name:Heidelberg University Hospital Represented in law by its Commercial Managing Director | ||||||||||||||||||
| Full Title: Improvement of functional Outcome for patients with newly diagnosed grade 2 or 3 glioma with co-deletion of 1p/19q - IMPROVE CODEL: the NOA-18 trial | ||||||||||||||||||
| Medical condition: WHO grade 2 or 3 glioma | ||||||||||||||||||
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| Population Age: Adults | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DE (Trial now transitioned) | ||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||
| EudraCT Number: 2021-003931-27 | Sponsor Protocol Number: GI2118 | Start Date*: 2021-10-20 | ||||||||||||||||
| Sponsor Name:Department of Oncology, Herlev & Gentofte Hospital | ||||||||||||||||||
| Full Title: Nivolumab, ipilimumab and radiation in combination with influenza vaccine in patients with pancreatic cancer. | ||||||||||||||||||
| Medical condition: Metastatic pancreatic cancer | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DK (Prematurely Ended) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2019-000245-12 | Sponsor Protocol Number: Repha_1436 | Start Date*: 2020-01-20 | ||||||||||||||||
| Sponsor Name:Repha GmbH | ||||||||||||||||||
| Full Title: Controlled clinical trial to evaluate the efficacy and safety of MYRRHINIL-INTEST® versus placebo in patients with diarrhea-dominant irritable bowel syndrome (IBS-D) and patients with mixed-type ir... | ||||||||||||||||||
| Medical condition: A confirmed diagnosis of irritable bowel syndrome (IBS-D or IBS-M) by a specialist in gastroenterology and/or internal medicine and/or general medicine | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DE (Trial now transitioned) | ||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||
| EudraCT Number: 2020-002327-11 | Sponsor Protocol Number: 213403 | Start Date*: 2021-02-05 | ||||||||||||||||
| Sponsor Name:GlaxoSmithKline Research & Development Ltd | ||||||||||||||||||
| Full Title: A RANDOMIZED, PHASE 2, DOUBLE-BLIND STUDY TO EVALUATE THE EFFICACY OF DOSTARLIMAB PLUS CHEMOTHERAPY VERSUS PEMBROLIZUMAB PLUS CHEMOTHERAPY IN METASTATIC NON-SQUAMOUS NON-SMALL CELL LUNG CANCER | ||||||||||||||||||
| Medical condition: Metastatic non-squamous non-small cell lung cancer | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DE (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned) RO (Trial now transitioned) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
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