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Clinical trials for Chronic Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,162 result(s) found for: Chronic Pain. Displaying page 8 of 59.
    EudraCT Number: 2009-012713-22 Sponsor Protocol Number: version 28.10.2009 Start Date*: 2010-05-06
    Sponsor Name:Medizinische Universität Wien, Univ. Klinik für Anästhesie, Allg. Intensivmedizin u Schmerztherapie
    Full Title: Randomized Double-blind Study Comparing the Efficacy of Duloxetine with Placebo in Patients with Chronic Low Back Pain
    Medical condition: efficacy of duloxetine in the treatment of patients with chronic low back pain to placebo
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-002248-40 Sponsor Protocol Number: F1J-MC-HMGC Start Date*: 2008-08-04
    Sponsor Name:Eli Lilly and Company
    Full Title: Effect of Duloxetine 60 mg Once Daily versus Placebo in Patients with Chronic Low Back Pain
    Medical condition: Chronic low back pain (CLBP)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-008235-28 Sponsor Protocol Number: 82772673 Start Date*: 2009-01-28
    Sponsor Name:Vesa Pakanen
    Full Title: Parasetamolin käyttö oheiskipulääkkeenä oksikodonin kanssa ohitusleikkauksen jälkeisen kivun hoidossa Paracetamol as Adjuctive Treatment for Postoperative Pain after Off-Pump Bypass Surgery
    Medical condition: Patient with chronic ischemic heart disease ongoing elective coronary artery bypass grafting. Any major organ failures like heart, kidney, liver failures are excluded.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008937 Chronic ischemic heart disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-006196-12 Sponsor Protocol Number: 160374 Start Date*: 2006-06-05
    Sponsor Name:Nottingham City Hospital NHS Trust
    Full Title: Epidural steroid injection in chronic, lumbar back pain; a cross-over, single-blinded study of Methyl-prednisolone 80mg versus Methyl-prednisolone 40mg.
    Medical condition: Chronic, lumbar back pain.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-004951-34 Sponsor Protocol Number: RESP301-005 Start Date*: 2020-12-11
    Sponsor Name:Thirty Respiratory Limited
    Full Title: Community participants with COPD or bronchiectasis and at risk of Respiratory Viral Infections including SARS-CoV-2: An open-label, multicentre feasibility study of an inhaled nitric oxide generati...
    Medical condition: Chronic obstructive pulmonary disease (COPD) and bronchiectasis
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10010952 COPD LLT
    21.0 10038738 - Respiratory, thoracic and mediastinal disorders 10006445 Bronchiectasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-005278-86 Sponsor Protocol Number: 147(Z)WO20157 Start Date*: 2021-06-14
    Sponsor Name:AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
    Full Title: Efficacy and safety of the combination of ibuprofen and paracetamol versus ibuprofen in monotherapy in acute Low Back Pain (LBP)
    Medical condition: Low Back Pain (LBP)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10024892 Low back pain (without radiation) LLT
    21.0 100000004859 10024891 Low back pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2013-002774-51 Sponsor Protocol Number: BrePainGenOxyc1 Start Date*: 2013-06-27
    Sponsor Name:Helsinki University Central Hospital
    Full Title: Genetic influences on pain and oxycodone consumption following mastectomy
    Medical condition: Women who are scheduled for breast cancer surgery.
    Disease:
    Population Age: Gender:
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2019-004943-54 Sponsor Protocol Number: STA-02 Start Date*: 2020-06-15
    Sponsor Name:Stayble Therapeutics AB
    Full Title: A multi-country, randomized, double-blind, placebo-controlled study investigating the efficacy and safety of STA363 at two concentrations (60 mg/mL and 120 mg/mL) compared to placebo in patients wi...
    Medical condition: Сhronic discogenic low back pain
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing) ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000550-37 Sponsor Protocol Number: NL52444.058.15 Start Date*: 2015-04-01
    Sponsor Name:LUMC
    Full Title: Effect of Sodium NItroprusside (SNP) on R,S- and S-Ketamine-induced psychotropic side effects, hemodynamic changes and pain relief in healthy volunteers
    Medical condition: Chronic pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001656-21 Sponsor Protocol Number: KF0151Y/06 Start Date*: 2005-08-11
    Sponsor Name:Grünenthal GmbH
    Full Title: A randomized, multi-center, double-blind, parallel-group, multiple-dose study assessing the analgesic efficacy and safety of 3 different doses of GRT0151Y compared to placebo and an active comparat...
    Medical condition: Postoperative pain following tonsillectomy
    Disease: Version SOC Term Classification Code Term Level
    8.0 10054711 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) CZ (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2017-000642-22 Sponsor Protocol Number: SEMG Start Date*: 2017-07-19
    Sponsor Name:Jose Alberola-Rubio
    Full Title: Electromyographic study for the help and guidance of Botox administration in the treatment of chronic pelvic floor pain
    Medical condition: Chronic pelvic pain
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003930-10 Sponsor Protocol Number: KEKU1 Start Date*: 2018-01-12
    Sponsor Name:Recherche et enseignement en douleur, anesthesie reanimation
    Full Title: KETAMINE'S EFFICIENCY IN THE TREATMENT OF CHRONIC PAIN WITH INFLAMMATORY COMPONENT: EXPLORING THE KYNURENIN PATHWAYS. A controlled, placebo-controlled, double-blind trial.
    Medical condition: The population selected is a spinal cord injury population with central neuropathic pain at the lesional or sub-lesion level, chronically (for more than three months) Adult, spinal cord injury (SCI...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015840-40 Sponsor Protocol Number: LEVO/HK Start Date*: 2009-10-19
    Sponsor Name:Belfast Health and Social Care Trust
    Full Title: Chronic pain and mobility outcomes following primary hip arthroplasty. A comparison of intravenous morphine with lumbar plexus levobupivacaine.
    Medical condition: Acute and chronic pain following hip replacement surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005061-20 Sponsor Protocol Number: ONU3705 Start Date*: 2012-06-19
    Sponsor Name:Purdue Pharma L.P.
    Full Title: A Randomized, Double-blind, Double-dummy, Placebo-controlled, Active-controlled, Parallel-group, Multicenter Trial of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess the Analgesic Eff...
    Medical condition: Opioid-induced Constipation & Moderate to Severe Chronic Low back Pain
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10071128 Opioid induced constipation LLT
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10003988 Back pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) PL (Completed) SK (Completed) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-002616-13 Sponsor Protocol Number: Unknown Start Date*: 2018-03-14
    Sponsor Name:Maastricht Universitair Medisch Centrum
    Full Title: The effect of perioperative intravenous s-ketamine on acute and chronic postoperative craniotomy pain compared to placebo
    Medical condition: Post operative craniotomy pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-003688-24 Sponsor Protocol Number: P12.??? Start Date*: 2012-12-12
    Sponsor Name:Leiden University Medical Center
    Full Title: Treatment of Complex Regional Pain Syndrome type 1: A randomized placebo controlled double-blind study with ARA 290
    Medical condition: Complex regional pain syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000906-12 Sponsor Protocol Number: AQX-1125-301 Start Date*: 2016-09-07
    Sponsor Name:Aquinox Pharmaceuticals (Canada) Inc.
    Full Title: The LEADERSHIP 301 Trial: A 12-Week, Randomized, Multi-Center, Double-Blind, Placebo-Controlled, 3 Arm, Parallel-Group, Phase 3 Trial to Evaluate the Efficacy and Safety of 2 Doses of AQX-1125 Targ...
    Medical condition: Interstitial Cystitis/Bladder Pain Syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004857 10071166 Bladder pain syndrome LLT
    20.0 100000004857 10008927 Chronic interstitial cystitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) HU (Completed) CZ (Completed) LV (Prematurely Ended) GB (Prematurely Ended) BE (Completed) ES (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003972-21 Sponsor Protocol Number: DS5565-A-U307 Start Date*: 2015-09-10
    Sponsor Name:Daiichi Sankyo, Inc.
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED SAFETY STUDY OF DS-5565 FOR TREATMENT OF PAIN DUE TO FIBROMYALGIA IN SUBJECTS WITH CHRONIC KIDNEY DISEASE
    Medical condition: DS-5565 is being investigated for the treatment of pain associated with fibromyalgia (FM) in subjects with chronic kidney disease.
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10048439 Fibromyalgia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) ES (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2022-000724-37 Sponsor Protocol Number: EP-DIC-TIO/75+4-F-01-2022 Start Date*: 2022-11-08
    Sponsor Name:EPIFARMA S.R.L.
    Full Title: Randomized, double-blind, parallel-groups, active - and placebo-controlled study to Evaluate the efficacy of a fixed combination of diclofenac 75 mg + thiocolchicoside 4 mg as solution for injectio...
    Medical condition: Low back pain (LBP) is one of the most frequent and disabling health problems. It is estimated that about 80% of adults will experience an episode of acute or chronic LBP at least once during their...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10076433 Lumbalgia LLT
    20.0 100000004859 10024988 Lumbago LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned) GR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-002143-95 Sponsor Protocol Number: M12-141 Start Date*: 2012-10-04
    Sponsor Name:Abbott GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-blind, Placebo- and Active-Controlled Study Comparing the Safety and Analgesic Efficacy of ABT-110 to Placebo in Subjects with Chronic Low Back Pain
    Medical condition: Chronic Low Back Pain
    Disease: Version SOC Term Classification Code Term Level
    15.0 10028395 - Musculoskeletal and connective tissue disorders 10008837 Chronic back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended) PL (Prematurely Ended) IT (Prematurely Ended) FI (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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