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Clinical trials for Ocular hypertension

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    166 result(s) found for: Ocular hypertension. Displaying page 8 of 9.
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    EudraCT Number: 2006-005237-38 Sponsor Protocol Number: Alcon CMS-06-12 Start Date*: 2007-06-27
    Sponsor Name:Alcon Laboratories, Inc.
    Full Title: SAFETY AND EFFICACY OF SWITCHING TO THE TRAVOPROST/TIMOLOL MALEATE FIXED COMBINATION (DUOTRAV) FROM PRIOR MONO- OR TWO-DRUG THERAPY IN GERMANY
    Medical condition: primary open-angle glaucoma ocular hypertension pigment dispersion glaucoma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10036719 Primary open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-001855-10 Sponsor Protocol Number: SNAP1 Start Date*: 2019-01-22
    Sponsor Name:Department of Ophtalmology, Rigshospitalet-Glostrup
    Full Title: Steroids and Non-steroidal Anti-inflammatory drugs in the Postoperative regime after trabeculectomy. An investigator-initiated randomized study (The SNAP study)
    Medical condition: Medically uncontrolled glaucoma that requires filtration surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10018326 Glaucoma NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-004106-25 Sponsor Protocol Number: EOP 1011E Start Date*: 2005-03-31
    Sponsor Name:(OSI) Eyetech, Inc
    Full Title: A Phase II randomised, dose-ranging, double-masked, multi-center trial, in parallel groups, to determine the safety, efficacy and pharmacokinetics of intravitreous injections of pegaptanib sodium c...
    Medical condition: Exudative Age Related Macular Degeneration (AMD)
    Disease: Version SOC Term Classification Code Term Level
    8 10025411 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001976-12 Sponsor Protocol Number: DWP 815, 116.01.05 Start Date*: 2005-06-20
    Sponsor Name:Dr. Winzer Pharma
    Full Title: 12-monatige, prospektive klinische Phase IV-Prüfung zur Untersuchung der lokalen und systemischen Verträglichkeit von Clonid-Ophtal® 1/8% AT versus Tim-Ophtal® 0,5% AT bei Patienten mit okulärer Hy...
    Medical condition: Offenwinkelglaukom oder okuläre Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005378-12 Sponsor Protocol Number: CL3-05153-006 Start Date*: 2016-01-05
    Sponsor Name:Institut de Recherche Internationales Servier
    Full Title: Efficacy and Safety of Fixed-Dose Combination atorvastatin/amlodipine/perindopril versus Fixed-Dose Combination of atorvastatin/ amlodipine in Patients with Hypertension and Dyslipidemia.
    Medical condition: hypertension and dyslipidemia
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004866 10020774 Vascular hypertensive disorders NEC HLT
    19.0 100000004861 10058110 Dyslipidemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001786-34 Sponsor Protocol Number: IT-04-01 Start Date*: 2005-05-16
    Sponsor Name:ALCON ITALIA
    Full Title: Hypotonic efficacy and tollerability of Travoprost in patient with open angle primary glaucoma and/or ocular hypertension, not controlled with dorzolamide + timolol treatment in fixed association...
    Medical condition: Reducing high intraocular pressure in patient with ocular hypertension or open-angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    6.1 10030348 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022128-63 Sponsor Protocol Number: LX211-11 Start Date*: 2011-03-16
    Sponsor Name:Lux Biosciences, Inc.
    Full Title: A Multi-center, Double-Masked, Parallel Group, Placebo-Controlled Study to Assess the Efficacy and Safety of Voclosporin as Therapy in Subjects with Active Non-Infectious Uveitis Involving the Inte...
    Medical condition: Non-Infectious Intermediate, Posterior or Pan-uveitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) IT (Completed) GB (Completed) NL (Ongoing) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004608-78 Sponsor Protocol Number: LSFG-1.2 Start Date*: 2017-03-03
    Sponsor Name:Kepler University Hospital, Institute of Ophthalmology
    Full Title: The Effect of Intravitreal Aflibercept on Ocular Perfusion – a Pilot Study
    Medical condition: Exudative AMD
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004853 10025411 Macular degeneration senile LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002601-30 Sponsor Protocol Number: QTM/OMN0111 Start Date*: 2011-09-26
    Sponsor Name:OMNIVISION GmbH
    Full Title: A COMPARISON OF LATANOPROST 50µg/ml EYE DROPS vs. XALATAN EYE DROPS IN THE TREATMENT OF OPEN ANGLE GLAUCOMA: AN OPEN, RANDOMIZED, CLINICAL TRIAL
    Medical condition: Open angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2022-002434-13 Sponsor Protocol Number: 01-INSULINAGLAUCOMA-2022 Start Date*: 2023-01-18
    Sponsor Name:Barbara Burgos-Blasco
    Full Title: RANDOMIZED CLINICAL TRIAL DOUBLE BLIND (WITH BLIND EVALUATOR) TO DETERMINE THE EFFECTIVENESS AND SAFETY OF TOPICAL INSULIN IN THE TREATMENT OF DRY EYE IN PATIENTS WITH TOPICAL HYPOTENSIVE DRUGS
    Medical condition: Dry eye disease in glaucoma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003042-16 Sponsor Protocol Number: IIBSP-PTE-2018-35 Start Date*: 2019-02-08
    Sponsor Name:Institut de Recerca H. de la Santa Creu i Sant Pau
    Full Title: Randomized clinical trial to evaluate the efficacy of fibrin membrane graft with eye drops concentrated in autologous growth factors in primary pterygium surgery comparing it with amniotic membrane...
    Medical condition: Pterigyum
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-006005-61 Sponsor Protocol Number: PRN 05-001 Start Date*: 2006-03-16
    Sponsor Name:Pharmaceutical Research Network, LLC
    Full Title: A COMPARISON OF THE EFFICACY AND SAFETY OF THE DORZOLAMIDE/TIMOLOL FIXED COMBINATION GIVEN TWICE DAILY VERSUS THE LATANOPROST/TIMOLOL FIXED COMBINATION GIVEN ONCE EVERY MORNING FOLLOWING A RUN-IN...
    Medical condition: open-angle glaucoma ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    10030348
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-005081-19 Sponsor Protocol Number: 1 Start Date*: 2014-07-10
    Sponsor Name:HOSPICES CIVILS DELYON
    Full Title: Phase II study evaluating the efficacy of aflibercept for the treatment of idiopathic choroidal neovascularization in young subjects: the INTUITION study
    Medical condition: idiopathic choroidal neovascularization
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004853 10060837 Choroidal neovascularization LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018853-36 Sponsor Protocol Number: Cos_Gan_PR/09 Start Date*: 2010-09-04
    Sponsor Name:Prof. Stefano Gandolfi-Universita` degli studi di Parma
    Full Title: Switching from beta blocker monotherapy to either ganfort � or cosopt �. A three months, single-blind , parallel group, randomized clinical trial in ocular hypertension/primary open angle glaucoma.
    Medical condition: Primary open angle glaucoma or ocular hypertensive patients, any level of intraocular pressure.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001128-35 Sponsor Protocol Number: A6641038 Start Date*: 2005-06-02
    Sponsor Name:Pfizer Pharma GmbH
    Full Title: A 12-week randomised, evaluator-masked, parallel-group, multinational, multi-centre study comparing the efficacy and safety of the fixed combination of latanoprost and timolol (XalacomTM) with the ...
    Medical condition: open angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    7.1 10030348 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-019505-42 Sponsor Protocol Number: LEG-SIL-LTX-03 Start Date*: 2010-05-26
    Sponsor Name:Rottapharm SpA
    Full Title: ESTUDIO ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO PARA EVALUAR LA EFICACIA Y SEGURIDAD DE LEGALON SIL EN EL TRATAMIENTO DE LA RECURRENCIA DE VHC EN EL INJERTO DE PACIENTES SOMETIDOS A UN T...
    Medical condition: Pacientes de 18-70 años afectados por VHC en espera de de un trasplante ortotópico de hígado / 18-70 years old patients affected by HCV awaiting orthotopic liver transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019975-30 Sponsor Protocol Number: 35131 Start Date*: 2010-08-24
    Sponsor Name:University Medical Center, Johannes Gutenberg-University Mainz
    Full Title: Investigation of the efficacy and safety of preoperative IOP reduction with preservative-free COSOPT-S® (dorzolamide/timolol, MSD) eye drops versus oral acetazolamide and dexamethasone eye drops an...
    Medical condition: Patients with glaucoma requiring trabeculectomy (filtration surgery)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10018304 Glaucoma LLT
    12.1 10050156 Glaucoma surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002384-16 Sponsor Protocol Number: TTD-11-01/AXI-IIG-01 Start Date*: 2011-09-21
    Sponsor Name:Grupo de Tratamiento de los Tumores Digestivos (TTD)
    Full Title: A Phase II study of Axitinib as maintenance for patients with advanced colorectal carcinoma.
    Medical condition: Advanced colorectal carcinoma
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-002238-35 Sponsor Protocol Number: 11002X-001 Start Date*: 2012-10-04
    Sponsor Name:Allergan Ltd.
    Full Title: A Multicenter, Double-masked, Randomized Study to Compare the Safety and Efficacy of an Investigational Eye Drop Formulation with OPTIVE™ Unit-Dose for 3 Months in Subjects with Dry Eye Disease
    Medical condition: Dry Eye Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10013774 Dry eye PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed) DE (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-000867-24 Sponsor Protocol Number: ALFR-HC-04 Start Date*: 2005-05-23
    Sponsor Name:Human Genome Sciences, Inc.
    Full Title: A PHASE 2b, RANDOMIZED, MULTI-CENTER, ACTIVE-CONTROLLED, OPEN-LABEL STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ALBUFERON (RECOMBINANT HUMAN ALBUMIN-INTERFERON ALFA FUSION PROTEIN) IN COMBINATION...
    Medical condition: Hepatitis type C chronic
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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