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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 820 of 2,219.
    «« First « Previous 816  817  818  819  820  821  822  823  824  Next» Last»»
    EudraCT Number: 2017-000613-22 Sponsor Protocol Number: CO-150225133959-HRCT Start Date*: 2018-10-15
    Sponsor Name:Johnson & Johnson Consumer Inc
    Full Title: A 16 Week, Single-center, Randomized, Placebo- and Active-controlled Proof of Principle Study to Assess the Efficacy and Safety of a 5% Minoxidil Topical Gel Formulation in Male subjects with Andro...
    Medical condition: Alopecia Androgentica
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-001756-35 Sponsor Protocol Number: 16/0163 Start Date*: 2019-06-21
    Sponsor Name:University of California, San Francisco
    Full Title: A Randomized, Double-Blind, Parallel-Group, Placebo Controlled Trial to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Clemastine Fumarate as a Remyelinating Agent in Acute Opti...
    Medical condition: acute optic neuritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10030942 Optic neuritis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-003406-11 Sponsor Protocol Number: NN1436-4465 Start Date*: 2019-04-09
    Sponsor Name:Novo Nordisk A/S
    Full Title: A trial comparing NNC0148-0287 C (insulin 287) versus insulin glargine U100, both in combination with metformin, with or without DPP4 inhibitors and with or without SGLT2 inhibitors, in insulin-naï...
    Medical condition: Diabetes Mellitus, Type 2
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SK (Completed) PL (Completed) HU (Completed) ES (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2014-004741-27 Sponsor Protocol Number: DM14/11351 Start Date*: 2015-02-18
    Sponsor Name:University of Leeds
    Full Title: Comparison of Alitretinoin with PUVA as the first line treatment in patients with severe chronic hand eczema
    Medical condition: Severe chronic hand eczema
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10066558 Chronic eczema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-001513-35 Sponsor Protocol Number: Start Date*: 2016-08-23
    Sponsor Name:NHS Blood and Transplant. [...]
    1. NHS Blood and Transplant.
    2. NHS Blood and Transplant
    Full Title: TREATT: TRial to EvaluAte Tranexamic acid therapy in Thrombocytopenia A double blind, randomised controlled trial evaluating the safety and efficacy of Tranexamic acid in patients with haematologic...
    Medical condition: Bleeding secondary to thrombocytopaenia associated to haematological malignancies.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10005103 Bleeding LLT
    20.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10066476 Haematological malignancy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-002225-38 Sponsor Protocol Number: 331-201-00083 Start Date*: 2018-02-23
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization, Inc.
    Full Title: A Multicenter, Open-label Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects with Bipolar I Disorder
    Medical condition: Treatment of Manic Episodes Associated with Bipolar I Disorder
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10068455 Bipolar I disorder, hypomanic LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed) PL (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2018-003284-62 Sponsor Protocol Number: 012508 Start Date*: 2019-07-18
    Sponsor Name:Queen Mary University London
    Full Title: A randomised, blinded, placebo controlled, Phase 2a study to evaluate the safety and efficacy of administering Regadenoson to patients with critical injury and signs of haemorrhagic shock
    Medical condition: Cardiovascular collapse following traumatic haemorrhage
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-004729-34 Sponsor Protocol Number: NOV-FR04 Start Date*: 2019-05-21
    Sponsor Name:Medical Center- Universtíty of Freiburg Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics
    Full Title: Effects of transdermal estrogen on Bone Mass in adolescent female patients with Anorexia nervosa (AN) – a placebo-controlled, double-blind, randomized, interventional study
    Medical condition: Anorexia nervosa
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002784-18 Sponsor Protocol Number: 13005 Start Date*: 2018-07-24
    Sponsor Name:Clinical Trials and Research Governance
    Full Title: Safety and efficacy of Tofacitinib in ameliorating ischaemia reperfusion injury and allograft pancreatitis in solid organ transplantation – a pilot study
    Medical condition: Ischaemia reperfusion injury and allograft pancreatitis.
    Disease: Version SOC Term Classification Code Term Level
    20.1 10017947 - Gastrointestinal disorders 10066127 Ischaemic pancreatitis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-002284-10 Sponsor Protocol Number: INS-4582 Start Date*: 2019-06-25
    Sponsor Name:Novo Nordisk A/S
    Full Title: A TRIAL TO COMPARE THE INJECTION SITE EXPERIENCE OF 0.25 MG SEMAGLUTIDE SC ADMINISTERED BY 2 DIFFERENT PRODUCTS
    Medical condition: Healthy volunteers (Diabetes Mellitus, Type 2) (Overweight) (Obesity)
    Disease: Version SOC Term Classification Code Term Level
    20.1 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    20.0 10027433 - Metabolism and nutrition disorders 10033307 Overweight PT
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2017-004645-24 Sponsor Protocol Number: 206852 Start Date*: 2018-11-09
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: A randomized, double blind, controlled mechanistic study of rituximab and belimumab combination therapy in PR3 ANCA-associated vasculitis
    Medical condition: ANCA-associated vasculitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021428 - Immune system disorders 10050894 Anti-neutrophil cytoplasmic antibody positive vasculitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-000992-34 Sponsor Protocol Number: 17915A Start Date*: 2018-11-13
    Sponsor Name:H. Lundbeck A/S
    Full Title: Interventional, randomized, double-blind, placebo-controlled study of the efficacy and safety of initial administration of 25 mg vortioxetine intravenously with 10 mg/day vortioxetine orally in ...
    Medical condition: Major Depressive disorder
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10057840 Major depression PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: LV (Completed) EE (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2019-000205-77 Sponsor Protocol Number: KF5503-75 Start Date*: Information not available in EudraCT
    Sponsor Name:Grünenthal GmbH
    Full Title: Open-label investigation of the pharmacokinetic profile, safety, tolerability, and efficacy of multiple administrations of tapentadol oral solution used for treatment of acute pain in children aged...
    Medical condition: Moderate to severe acute pain
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10066714 Acute pain LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2018-004986-15 Sponsor Protocol Number: Protocol_AFCN_17022019 Start Date*: 2019-02-18
    Sponsor Name:Aarhus University Hospital
    Full Title: Ultrasound-guided nerve block of the anterior femoral cutaneous nerves in healthy volunteers
    Medical condition: Pain around the surgical incision after total knee arthroplasty (TKA). The area anesthetized by a combination of nerve block techniques anesthetizing the anterior femoral cutaneous nerves are inve...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10036236 Postoperative pain relief LLT
    20.0 100000004865 10002325 Anesthesia local LLT
    20.1 10022891 - Investigations 10045434 Ultrasound scan PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-000641-23 Sponsor Protocol Number: CNWL/MC/AFT/01 Start Date*: 2015-11-24
    Sponsor Name:Central and North West London NHS Foundation Trust
    Full Title: Aggression Following TBI: Effectiveness of Risperidone (AFTER)-a feasibility RCT.
    Medical condition: aggression and agitation following on from a traumatic brain injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-003113-17 Sponsor Protocol Number: MEU17/361 Start Date*: 2018-11-09
    Sponsor Name:The Medicines Evaluation Unit (MEU) Ltd. (Investigator led study)
    Full Title: A randomised, open label 2-way cross-over study to compare the effects of inhaled Beclometasone/Formoterol/Glycopyrronium (TRIMBOW) pMDI to Beclometasone/Formoterol (FOSTAIR) pMDI on hyperinflation...
    Medical condition: Chronic obstructive pulmonary disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001237-14 Sponsor Protocol Number: LIGRADIS Start Date*: 2019-06-11
    Sponsor Name:Dr. Jesús María Villar del Moral and Dr. José Luis Muñoz de Nova
    Full Title: Randomized clinical trial, blinded for the researcher and multicenter, to evaluate the efficacy and safety of preoperative preparation with Lugol solution in euthyroid patients with Graves-Basedow ...
    Medical condition: Graves-Basedow disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10065624 Graves-Basedow disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001656-19 Sponsor Protocol Number: RP-L301-0119 Start Date*: 2019-09-19
    Sponsor Name:Rocket Pharmaceuticals, Inc.
    Full Title: Gene Therapy for Pyruvate Kinase Deficiency (PKD): A Phase I Clinical Trial to Evaluate the Safety of the Infusion of Autologous CD34+ Cells Transduced with a Lentiviral Vector Carrying the Codon O...
    Medical condition: Pyruvate kinase deficiency
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10037682 Pyruvate kinase deficiency anaemia PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001305-82 Sponsor Protocol Number: IC3627/18 Start Date*: 2019-05-16
    Sponsor Name:Laura Perelló Moreno
    Full Title: Study on the advantages of local post-operative infiltration in forefoot surgery.
    Medical condition: management of postoperative pain in ambulatory foot surgery that allows the realization of immediate rehabilitation and better functional results and personal satisfaction
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003936-62 Sponsor Protocol Number: PRONE Start Date*: 2019-06-13
    Sponsor Name:HOSPITAL UNIVERSITARI DE BELLVITGE-IDIBELL
    Full Title: RENINE ANGIOTENSINE SYSTEM BLOCKADE (RAAS) IN RENAL TRANSPLANT RECIPIENTS WITH RENAL PROGENITOR CELLS (PEC's) IN URINE: RANDOMIZED CLINICAL TRIAL
    Medical condition: POST TRANSPLANT RENAL GLOMERULOPATHY
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10038533 Renal transplant PT
    20.1 100000004870 10063210 Transplant glomerulopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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