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Clinical trials for Cardiac surgical procedures

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    261 result(s) found for: Cardiac surgical procedures. Displaying page 1 of 14.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-004485-28 Sponsor Protocol Number: 38RC15.214 Start Date*: 2016-01-18
    Sponsor Name:Centre Hospitalier Universitaire de Grenoble
    Full Title:
    Medical condition: Patients should be operated for cardiac surgery with cardiac bypass and in sinus rhythm, and for which the fact of the existence of impaired left ventricular function or the heaviness of the surgic...
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10061026 Cardiac operation PT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2004-000100-40 Sponsor Protocol Number: f7card-1610 Start Date*: 2004-08-18
    Sponsor Name:Novo Nordisk A/S
    Full Title: Estudio multicentrico. aleatorizado, doble ciego, controlado con placebo y con escalada de dosis sobre la seguridad y la eficacia del factor VII recombinante activado (rFVIIa/NovoSeven) en el trata...
    Medical condition: Enfermedad de corazon/cirugia cardiaca.
    Disease: Version SOC Term Classification Code Term Level
    10061026
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) SE (Prematurely Ended) GB (Prematurely Ended) IT (Prematurely Ended) DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-000459-10 Sponsor Protocol Number: PADIT Start Date*: 2014-06-10
    Sponsor Name:Population Health Research Institute (PHRI)
    Full Title: A cluster Crossover Trial Comparing Conventionl vs Incremental Antibiotic Therapy for the Prevention or Arrhytmia Device Infection
    Medical condition: high-risk patients undergoing arrhythmia device procedures
    Disease: Version SOC Term Classification Code Term Level
    16.1 10007541 - Cardiac disorders 10003119 Arrhythmia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-003088-76 Sponsor Protocol Number: 11-170 Start Date*: 2014-07-14
    Sponsor Name:Clinical Evaluation Research Unit (CERU)
    Full Title: SodiUm SeleniTe Adminstration IN Cardiac Surgery surgery (SUSTAIN CSX®-trial) - A randomized controlled trial of high dose sodium-selenite administration in high risk cardiac surgical patients
    Medical condition: Selenium is a key component of a number of selenoproteins which protect against oxidative stress and is well recognised for its prominent role in immune defence. Selenoproteins have the potential t...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001756-19 Sponsor Protocol Number: MTP-2019-01 Start Date*: 2019-12-11
    Sponsor Name:María de los Ángeles Tena Pajuelo (Investigador independiente)
    Full Title: MULTI-CENTER, DOUBLE-BLIND, CONTROLLED, PARALLEL AND RANDOMIZED STUDY TO COMPARE THE EFFECTIVENESS OF 0.1 ΜG / KG / MIN OF LEVOSIMENDAN VERSUS PLACEBO IN THE POSTOPERATIVE OF CARDIAC PROGRAMMED SUR...
    Medical condition: Patients who have preoperatively severe left ventricular dysfunction (LVEF ≤ 35%) and will be scheuled for cardiac surgery on cardiopulmonary bypass.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-000177-39 Sponsor Protocol Number: Linea7-2013/06-APPEAR Start Date*: 2014-07-17
    Sponsor Name:IRCCS Policlinico San Donato
    Full Title: Albumin vs. Plasma for PEdiAtric pRiming (APPEAR) trial
    Medical condition: Congenital cardiac diseases needing surgical correction requiring intervention with extracorporeal circulation
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002207-17 Sponsor Protocol Number: D-PLEX-302 Start Date*: 2020-07-14
    Sponsor Name:PolyPid Ltd.
    Full Title: A Phase III, Prospective, Multinational, Multicenter, Randomized, Parallel Controlled, Two arms, Single Blind, Study to Assess the Efficacy and Safety of D-PLEX Administered Concomitantly with the ...
    Medical condition: Prevention of Post-Cardiac Surgery Sternal Infections
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10078408 Surgical site infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004894-96 Sponsor Protocol Number: 2011-10-03 Start Date*: 2012-03-20
    Sponsor Name:Mikko Hippeläinen [...]
    1. Mikko Hippeläinen
    2. Mikko Hippeläinen
    Full Title: ORAL ABSORPTION OF OXYCODONE AFTER CARDIAC BYPASS SURGERY
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10058829 Elective surgery PT
    14.1 10042613 - Surgical and medical procedures 10054366 Coronary revascularization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000201-24 Sponsor Protocol Number: O3Cardio Start Date*: 2018-08-01
    Sponsor Name:Bernardino Clavo - Hospital Dr. Negrín
    Full Title: Effectiveness and cost-effectiveness of Ozone therapy in patients with ischemic heart disease refractory to medical and surgical treatment: Randomized, triple-blind clinical trial.
    Medical condition: Ischemic heart disease refractory to medical and surgical treatment.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    20.0 100000004849 10055224 Cardiac ischemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000404-28 Sponsor Protocol Number: CRAD001ANO05 Start Date*: 2016-07-20
    Sponsor Name:Novartis Norge AS
    Full Title: 5, 6 or 7 year follow-up control after the SCHEDULE study (SCANDINAVIAN HEART TRANSPLANT EVEROLIMUS DE NOVO STUDY WITH EARLY CNI AVOIDANCE) Title of the original SCHEDULE study: A controlled ran...
    Medical condition: Heart transplantation
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10019314 Heart transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-003831-20 Sponsor Protocol Number: 2008/27 Start Date*: 2008-11-18
    Sponsor Name:Hopital Foch
    Full Title: Comparaison de l'effet de deux doses d'Acide Tranexamique sur les besoins transfusionnels en chirurgie cardiaque
    Medical condition: cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048935 Open heart surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-009115-22 Sponsor Protocol Number: IGG-LR-08 Start Date*: 2009-05-04
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Fenoldopam mesilate efficacy to control splancnic ischemia during cardiopulmonary bypass in pediatric patients
    Medical condition: cardiac surgery with CPB
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042613 SOC
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013074-41 Sponsor Protocol Number: CRAD001ANO02 Start Date*: 2009-11-10
    Sponsor Name:Novartis Norge AS
    Full Title: A controlled randomized open-label multicentre study evaluating if early initiation of everolimus (Certican®)and early elimination of cyclosporine (Sandimmun Neoral®) in de novo heart transplant re...
    Medical condition: Heart transplantation
    Disease: Version SOC Term Classification Code Term Level
    16.1 10042613 - Surgical and medical procedures 10019314 Heart transplant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2017-000442-21 Sponsor Protocol Number: RC17_0029 Start Date*: 2017-09-12
    Sponsor Name:CHU de Nantes
    Full Title: Effects of perioperative administration of dexamethasone on postoperative complications and mortality after non-cardiac major surgery : a randomized, multicentre, double blind, study
    Medical condition: non-cardiac major surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2010-022679-71 Sponsor Protocol Number: Xenon-MTH-Studie Start Date*: 2011-01-07
    Sponsor Name:Clinical Trials Center Aachen, University of Aachen
    Full Title: Xenon and Therapeutical Hypothermia After Successful Cardiopulmonary Resuscitation
    Medical condition: In this clinical trial will be checked, whether 2 hours ventilation with xenon has neuroprotetctive effect on the patients, which had out of hospital cardiac arrest and successful cardiopulmonary r...
    Disease: Version SOC Term Classification Code Term Level
    16.1 10042613 - Surgical and medical procedures 10067221 Mechanical ventilation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003557-24 Sponsor Protocol Number: 400-12-004 Start Date*: 2014-04-02
    Sponsor Name:Ethicon Inc
    Full Title: A Prospective, Randomised, Controlled, Study Evaluating the Safety and Effectiveness of EVARREST® Sealant Matrix in Controlling Mild or Moderate Hepatic Parenchyma or Soft Tissue Bleeding During O...
    Medical condition: Mild or moderate hepatic parenchyma or soft tissue bleeding during open, abdominal, retroperitoneal, pelvic and thoracic (non-cardiac) surgery
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005920-16 Sponsor Protocol Number: CHUB-930105 Start Date*: 2012-02-06
    Sponsor Name:Association Hospitalière CHU Brugmann
    Full Title: Prospective, controled, randomized, double blind monocentric study evaluating the efficacy of the basic component of colloids (corn versus potato) on perioperative blood losses in elective cardiac ...
    Medical condition: Elective cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2022-001759-17 Sponsor Protocol Number: FGTW2101 Start Date*: 2022-10-04
    Sponsor Name:Laboratoire français du Fractionnement et des Biotechnologies (LFB BIOTECHNOLOGIES)
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel, phase 3 study to assess the efficacy and safety of fibrinogen concentrate (FGTW) in the management of bleeding in patients und...
    Medical condition: Bleeding in patients undergoing complex cardiac surgery (involving CPB)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned) ES (Ongoing) DE (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-023093-39 Sponsor Protocol Number: SIRS Start Date*: 2011-09-08
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: Steroids In caRdiac Surgery Trial
    Medical condition: Require CPB for any cardiac surgical procedure
    Disease: Version SOC Term Classification Code Term Level
    13.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) CZ (Completed) ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005291-34 Sponsor Protocol Number: NL41467 Start Date*: 2014-02-14
    Sponsor Name:AMC, Amsterdam
    Full Title: Perioperative intravenous insulin, GIK or GLP-1 treatment in DM
    Medical condition: Patients with diabetes mellitus type 2 who will undergo non-cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10058829 Elective surgery PT
    19.0 100000004861 10049746 Insulin-requiring type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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