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Clinical trials for Crown

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    39 result(s) found for: Crown. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2021-001885-40 Sponsor Protocol Number: Syst-AB+Sinus Start Date*: 2022-02-24
    Sponsor Name:Universidad Complutense de Madrid
    Full Title: The effect of systemic antibiotics on post-surgical complications and paitent-centered outomes in patients undergoing implant surgery with the guided bone regeneration and simultaneous sinus floor ...
    Medical condition: The medical condition that the patients have in this trial is edentulism in a posterior maxillary quadrant of the mouth with a sinus pneumatisation/ decreased crestal bone heigh defect requiring a...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002694-19 Sponsor Protocol Number: 62449 Start Date*: 2018-02-22
    Sponsor Name:Radboud University Medical Centre
    Full Title: Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: a randomized double blind placebo-controlled comparison (M&M trial).
    Medical condition: Early pregnancy failure
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019955-23 Sponsor Protocol Number: LWH 0852 Start Date*: 2010-12-29
    Sponsor Name:Liverpool Women's NHS Foundation Trust [...]
    1. Liverpool Women's NHS Foundation Trust
    2. Liverpoool Womens NHS Foundation Trust
    Full Title: To evaluate the pharmakcokinetics, tolerability and short term safety of ciprofloxacin in neonates and infants with suspected (or proven) Gram Negative Infection Open Label pilot PK study - TINN T...
    Medical condition: Pharmacokinetics of ciprofloxacin used for suspected or proven gram negative sepsis.
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003307-36 Sponsor Protocol Number: LWH0606 Start Date*: 2005-12-08
    Sponsor Name:University of Liverpool/Liverpool Women's Hospital
    Full Title: A randomised controlled trial of prednisolone for women with recurrent miscarriage and high levels of uNK cells in the endometrium
    Medical condition: Idopathic recurrent miscarriage
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000599-33 Sponsor Protocol Number: LWH0646 Start Date*: 2006-08-21
    Sponsor Name:Liverpool Women's NHS Foundation Trust
    Full Title: Duration of luteal phase support with progesterone pessaries to improve the success rate in assisted reproduction cycles. A prospective randomised control trial.
    Medical condition: Women undergoing assisted conception
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005738-12 Sponsor Protocol Number: LIPSTIC.V.01 Start Date*: 2013-03-27
    Sponsor Name:Alder Hey Children's NHS Foundation Trust
    Full Title: Liverpool Pharmacokinetic/pharmacodynamics study of teicoplanin in children (LIPSTIC).
    Medical condition: Gram-positive bacterial infection: late-onset neonatal sepsis, central line-associated blood stream infection, ventilator-associated pneumonia.
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006617-32 Sponsor Protocol Number: 06/Q0605/1 Start Date*: 2007-05-02
    Sponsor Name:Kings College Hospital Trust R&D
    Full Title: A prospective randomised double blind parallel trial comparing Articaine versus Lignocaine for mandibular dentistry
    Medical condition: necessary dental surgery
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-002952-34 Sponsor Protocol Number: ACH-UCP-301 Start Date*: 2015-12-07
    Sponsor Name:Atlantic Pharmaceuticals Limited
    Full Title: A Randomised, Double-Blind, Placebo-Controlled Trial of the Safety and Efficacy of Topical Alicaforsen Enema in Subjects with Active, Chronic, Antibiotic Refractory Primary Idiopathic Pouchitis
    Medical condition: Active, Chronic, Antibiotic Refractory Primary Idiopathic Pouchitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10036463 Pouchitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) NL (Completed) IE (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-008899-14 Sponsor Protocol Number: LWH0776 Start Date*: 2009-06-25
    Sponsor Name:Liverpool Women's NHS Foundation Trust
    Full Title: Standardised, Concentrated, Additional Macronutrients, Parenteral (SCAMP) nutrition in very preterm infants: a phase IV randomised controlled study of macronutrient intake, growth and implications ...
    Medical condition: Prematurity
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000832-28 Sponsor Protocol Number: LWH0642 Start Date*: 2006-07-04
    Sponsor Name:Liverpool Women's NHS Foundation Trust
    Full Title: Dopamine pharmacokinetics in extremely premature infants: a pilot study
    Medical condition: Neonatal hypotension
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-000585-38 Sponsor Protocol Number: SQ411218 Start Date*: 2019-08-20
    Sponsor Name:University Hospitals Coventry and Warwickshire NHS Trust
    Full Title: Chronic Endometritis and Recurrent Miscarriage - The CERM trial
    Medical condition: Chronic Endometritis and Recurrent Miscarriage
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-001402-38 Sponsor Protocol Number: CTU/2020/352 Start Date*: 2020-10-20
    Sponsor Name:University College London
    Full Title: An international, Bayesian platform adaptive, randomized, placebo-controlled trial assessing the effectiveness of candidate interventions in preventing COVID-19 disease in healthcare workers.
    Medical condition: Coronavirus disease 2019 (COVID-19), also known as SARS-CoV-2 infection
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10084268 COVID-19 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-001554-10 Sponsor Protocol Number: NL57892 Start Date*: 2016-06-21
    Sponsor Name:Radboudumc
    Full Title: Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: a pilot study
    Medical condition: Women aged above 18 years with early pregnancy failure, 6-14 weeks postmenstrual.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10068522 Non-surgical treatment LLT
    19.0 100000004868 10027650 Miscarriage of pregnancy LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2017-001007-72 Sponsor Protocol Number: 80-84800-98-41027 Start Date*: 2017-07-06
    Sponsor Name:Amsterdam UMC location AMC
    Full Title: Atosiban versus placebo in the treatment of late threatened preterm birth (APOSTEL VIII).
    Medical condition: Neonatal outcome in threatened preterm birth between 30 and 34 weeks of gestation.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-002982-20 Sponsor Protocol Number: 5155 Start Date*: 2020-01-29
    Sponsor Name:Royal Liverpool University Hospital
    Full Title: A Pilot Study to assess the efficacy and safety of reduced dose oral iron in the treatment of iron deficiency anaemia in inflammatory bowel disease patients
    Medical condition: Iron deficiency anaemia in inflammatory bowel disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10002062 Anaemia iron deficiency LLT
    20.1 10017947 - Gastrointestinal disorders 10021972 Inflammatory bowel disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-003099-39 Sponsor Protocol Number: LWH0604 Start Date*: 2008-08-21
    Sponsor Name:Liverpool Women's NHS Foundation Trust Hospital
    Full Title: A Randomised Controlled Trial of Thyroxine in Preterm Infants Under 28 weeks' Gestation.
    Medical condition: Hypothyroidism is a condition where there is a lack of thyroid hormone in the body. Thyroid hormones are important for normal brain development and growth. Children who are born with low thyroid ho...
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002949-20 Sponsor Protocol Number: LWH0747 Start Date*: 2008-04-28
    Sponsor Name:Liverpool Women's NHS Foundation Trust
    Full Title: Randomised controlled trial comparing the effects of oxytocin 5 units IV bolus vs oxytocin 5 units IV infusion on cardiac output during caesarean section
    Medical condition: The drug is given routinely to women during caesarean section to help the womb contract after their baby has been delivered. This helps reduce the risk of bleeding after surgery. For this trial, ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006924 Caesarean section LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-001939-27 Sponsor Protocol Number: SystABSinus01 Start Date*: 2021-02-25
    Sponsor Name:Medizinische Universität Graz, Universitätsklinik für Zahn-, Mund- und Kieferheilkunde
    Full Title: The effect of systemic antibiotics on post-surgical complications and patient-centered outcomes in patients undergoing implant surgery with guided bone regeneration and simultaneous sinus floor ele...
    Medical condition: patients undergoing oral implant therapy with simultaneous lateral sinus floor elevation and guided bone regeneration (GBR)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-002905-89 Sponsor Protocol Number: 20186 Start Date*: 2022-10-19
    Sponsor Name:BAYER AG
    Full Title: An 18-month, open-label, single-arm safety extension study of an age-and bodyweight-adjusted oral finerenone regimen, in addition to an ACEI or ARB, for the treatment of children and young adults f...
    Medical condition: Treatment of children with chronic kidney disease and proteinuria
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned) ES (Trial now transitioned) BE (Trial now transitioned) NL (Trial now transitioned) AT (Trial now transitioned) DK (Trial now transitioned) GR (Trial now transitioned) CZ (Trial now transitioned) SE (Trial now transitioned) PL (Trial now transitioned) LT (Trial now transitioned) FR (Trial now transitioned) PT (Trial now transitioned) DE (Trial now transitioned) FI (Trial now transitioned) HU (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-004478-41 Sponsor Protocol Number: LCC001 Start Date*: 2015-03-10
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guy's and St Thomas' NHS Foundation Trust
    Full Title: Phase III trial in IntrahepaTic CHolestasis of pregnancy (ICP) to Evaluate urSodeoxycholic acid (UDCA) in improving perinatal outcomes
    Medical condition: Intrahepatic Cholestasis of pregnancy
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004871 10008638 Cholestasis intrahepatic LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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