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Clinical trials for Focal seizures

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    151 result(s) found for: Focal seizures. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2004-000152-16 Sponsor Protocol Number: SP774 Start Date*: 2004-10-13
    Sponsor Name:SCHWARZ BIOSCIENCES GmbH; A member of the UCB group
    Full Title: An international open-label extension trial to determine safety and efficacy of long-term oral SPM 927 in patients with partial seizures
    Medical condition: Partial seizures
    Disease: Version SOC Term Classification Code Term Level
    6.0 10034089 LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) HU (Completed) CZ (Completed) FI (Completed) SE (Completed) ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001982-33 Sponsor Protocol Number: E2090-E044-401 Start Date*: 2005-09-05
    Sponsor Name:Eisai Limited
    Full Title: An open label study of Zonegran (zonisamide) in patients with partial onset seizures.
    Medical condition: Indicated as adjunctive therapy in the treatment of adult patients with partial seizures, with or without secondary generalisation.
    Disease: Version SOC Term Classification Code Term Level
    8.0 10061334 pt
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) AT (Completed) SE (Completed) DK (Completed) FI (Completed) DE (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-004265-12 Sponsor Protocol Number: NBI-921352-FOS2022 Start Date*: 2021-12-21
    Sponsor Name:Neurocrine Biosciences, Inc.
    Full Title: Prospective, Long-Term, Interventional, Active Extension Study to Evaluate the Safety and Tolerability of NBI-921352 as Adjunctive Therapy in Subjects with Focal Onset Seizures (FOS)
    Medical condition: Focal Onset Seizures (FOS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10016843 Focal seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) FR (Completed) HU (Prematurely Ended) ES (Ongoing) IT (Prematurely Ended) BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002322-22 Sponsor Protocol Number: SP757 Start Date*: 2005-01-12
    Sponsor Name:SCHWARZ BIOSCIENCES Inc.
    Full Title: A multi-center, open-label trial to investigate the safety and tolerability of intravenous SPM 927 as replacement for oral SPM 927 in subjects with partial seizures with or without secondary genera...
    Medical condition: partial seizures with or without secondary generalization
    Disease: Version SOC Term Classification Code Term Level
    6.0 10034089 LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) SE (Completed) DE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2004-000199-14 Sponsor Protocol Number: N01009 Start Date*: 2004-11-25
    Sponsor Name:UCB Pharma S.A. [...]
    1. UCB Pharma S.A.
    2. UCB Pharma Inc.
    Full Title: A double-blind, randomized, multicenter, placebo-controlled, in-patients maximum 34 day study of levetiracetam oral solution (20-50 mg/kg/day) as adjunctive treatment of refractory partial onset se...
    Medical condition: Epilepsy - Refractory Partial Onset Seizures
    Disease: Version SOC Term Classification Code Term Level
    7.0 10061334 LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) BE (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-005344-27 Sponsor Protocol Number: YKP3089C040 Start Date*: 2022-02-03
    Sponsor Name:SK Life Science, Inc.
    Full Title: Open-Label Safety and Efficacy Study of Cenobamate (YKP3089) in Pediatric Subjects with Partial-onset (Focal) Seizures
    Medical condition: partial onset (focal) seizures
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10016843 Focal seizures LLT
    21.1 10029205 - Nervous system disorders 10061334 Partial seizures PT
    20.0 10029205 - Nervous system disorders 10039910 Seizures LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) HU (Trial now transitioned) PL (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001433-39 Sponsor Protocol Number: NBI-921352-FOS2021 Start Date*: 2021-09-08
    Sponsor Name:Neurocrine Biosciences, Inc.
    Full Title: A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study to Investigate Safety, Tolerability, Pharmacokinetics, and Efficacy of NBI-921352 as Adjunctive Therapy in Adult Subjects ...
    Medical condition: Focal Onset Seizures (FOS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10016843 Focal seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed) FR (Completed) IT (Completed) BE (Completed) ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2005-004023-19 Sponsor Protocol Number: A0081046 Start Date*: 2006-05-25
    Sponsor Name:Pfizer Ltd, Ramsgate Rd, Sandwich, Kent, United Kingdom
    Full Title: A RANDOMIZED, COMPARATIVE, DOUBLE-BLIND, PARALLEL-GROUP, MULTICENTER, MONOTHERAPY, STUDY OF PREGABALIN (LYRICA) AND LAMOTRIGINE (LAMICTAL) IN PATIENTS WITH NEWLY DIAGNOSED PARTIAL SEIZURES
    Medical condition: Epilepsy; Patients with newly diagnosed partial seizures (with or without secondary generalization)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061334 Partial seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) PT (Completed) ES (Completed) BE (Completed) IE (Completed) CZ (Completed) LT (Completed) DE (Completed) SK (Completed) IT (Completed) HU (Completed) FI (Completed) EE (Completed) BG (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2006-000173-29 Sponsor Protocol Number: N01237 Start Date*: 2006-04-13
    Sponsor Name:UCB S.A. (Global Medical Affairs)
    Full Title: A multicenter, open-label single-arm follow-up trial evaluating the long-term safety of levetiracetam, for patients suffering from epilepsy and coming from the study N01175.
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10061334 LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-003161-40 Sponsor Protocol Number: A0081143 Start Date*: 2007-12-14
    Sponsor Name:Pfizer Inc,East 42nd street,New york, NY10017, USA
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP, MULTI-CENTER, COMPARATIVE, FLEXIBLE DOSE TRIAL OF PREGABALIN VERSUS GABAPENTIN AS ADJUNCTIVE THERAPY IN SUBJECTS WITH PARTIAL SEIZURES
    Medical condition: Adjunctive treatment for subjects with partial seizures, with or without secondary generalization.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061334 Partial seizures PT
    9.1 10056209 Partial seizures with secondary generalisation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) ES (Completed) BG (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2013-003420-37 Sponsor Protocol Number: A0081042 Start Date*: 2014-05-16
    Sponsor Name:Pfizer Inc. 235 East 42nd Street, New York, NY 10017
    Full Title: A DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, MULTICENTER STUDY OF THE EFFICACY AND SAFETY OF PREGABALIN AS ADJUNCTIVE THERAPY IN CHILDREN 1 MONTH THROUGH <4 YEARS OF AGE WITH PARTIAL ONSET S...
    Medical condition: Partial onset seizures
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004852 10034089 Partial seizures NOS LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) HU (Completed) NL (Prematurely Ended) ES (Completed) DE (Completed) PL (Completed) SK (Completed) GR (Completed) PT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2010-020730-26 Sponsor Protocol Number: A0081074 Start Date*: 2010-10-08
    Sponsor Name:Pfizer Inc.235 East 42nd Street, New York, NY 10017
    Full Title: A PLACEBO-CONTROLLED, ESCALATING DOSE, MULTIPLE DOSE STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND PHARMACOKINETICS OF PREGABALIN IN PEDIATRIC PATIENTS WITH PARTIAL ONSET SEIZURES
    Medical condition: PARTIAL ONSET SEIZURES
    Disease: Version SOC Term Classification Code Term Level
    12.1 10034089 Partial seizures NOS LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2010-020731-39 Sponsor Protocol Number: A0081075 Start Date*: 2010-10-08
    Sponsor Name:Pfizer Inc.235 East 42nd Street, New York, NY 10017
    Full Title: A 12-MONTH OPEN-LABEL EXTENSION STUDY EVALUATING THE SAFETY AND TOLERABILITY OF FLEXIBLE DOSES OF PREGABALIN IN PEDIATRIC PATIENTS WITH PARTIAL ONSET SEIZURES
    Medical condition: PARTIAL ONSET SEIZURES
    Disease: Version SOC Term Classification Code Term Level
    12.1 10034089 Partial seizures NOS LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-016849-25 Sponsor Protocol Number: A0081047 Start Date*: 2010-03-15
    Sponsor Name:Pfizer Inc
    Full Title: A DOUBLE-BLIND, RANDOMIZED, MULTICENTER EFFICACY AND SAFETY STUDY OF PREGABALIN (LYRICA) AS MONOTHERAPY IN PATIENTS WITH PARTIAL SEIZURES
    Medical condition: Partial Seizures
    Disease: Version SOC Term Classification Code Term Level
    12.1 10061334 Partial seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-002594-11 Sponsor Protocol Number: GWEP1330 Start Date*: 2015-01-24
    Sponsor Name:GW Research Ltd.
    Full Title: A double blind, randomized, placebo-controlled, two-part study to investigate the pharmacokinetics, followed by efficacy and safety of GWP42006 as add-on therapy in patients with inadequately contr...
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004852 10016843 Focal seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) ES (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-000987-10 Sponsor Protocol Number: N01235 Start Date*: 2006-07-27
    Sponsor Name:UCB S.A. [...]
    1. UCB S.A.
    2. UCB Inc.
    Full Title: A double-blind, placebo-controlled, randomized efficacy and safety study of levetiracetam extended release formulation (LEV XR), administered as 2 x 500 mg LEV XR tablets once daily as add-on thera...
    Medical condition: Refractory epilepsy suffering from partial onset seizures
    Disease: Version SOC Term Classification Code Term Level
    8.1 10061334 Partial seizures LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2008-005065-64 Sponsor Protocol Number: CBGG492A2202 Start Date*: 2009-03-12
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, double-blind, randomized, placebo-controlled, two-arm parallel-group study of BGG492 as monotherapy in individuals with refractory partial seizures undergoing inpatient evaluation fo...
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061334 Partial seizures LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-002303-33 Sponsor Protocol Number: EP0092 Start Date*: 2019-01-03
    Sponsor Name:UCB Biopharma SPRL
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-Onset Seizures in Adult Subjects...
    Medical condition: Focal-Onset Seizures
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10065337 Focal epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) DE (Prematurely Ended) BE (Completed) GB (Completed) HU (Completed) NL (Completed) DK (Completed) SE (Completed) AT (Completed) GR (Completed) BG (Completed) FI (Completed) ES (Prematurely Ended) CZ (Completed) HR (Completed) FR (Completed) PT (Completed) SK (Prematurely Ended) IT (Prematurely Ended) RO (Completed)
    Trial results: View results
    EudraCT Number: 2012-001132-60 Sponsor Protocol Number: RTG113284 Start Date*: 2012-03-09
    Sponsor Name:GlaxoSmithKline R&D Limited
    Full Title: Open-label, multiple dose study to evaluate the pharmacokinetics, safety and tolerability of ezogabine/retigabine as adjunctive treatment in subjects aged from 12 years to less than 18 years wit...
    Medical condition: Uncontrolled partial onset seizures or Lennox Gastaut Syndrome
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10061334 Partial seizures PT
    14.1 10029205 - Nervous system disorders 10048816 Lennox-Gastaut syndrome PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-003241-26 Sponsor Protocol Number: EP0093 Start Date*: 2018-09-04
    Sponsor Name:UCB Biopharma SPRL
    Full Title: An Open-Label, Multicenter, Extension Study to Evaluate the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-Onset Seizures in Adult Subjects with Drug-Resistant Epilepsy
    Medical condition: Focal-Onset Seizures
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10065337 Focal epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Prematurely Ended) HU (Prematurely Ended) ES (Prematurely Ended) CZ (Completed) BG (Completed) FR (Completed) LT (Completed) BE (Completed) PT (Prematurely Ended) EE (Completed) NL (Completed) DK (Completed) AT (Completed) GR (Completed) FI (Completed) NO (Completed) SE (Completed) HR (Completed) IT (Completed) RO (Completed)
    Trial results: View results
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