- Trials with a EudraCT protocol (72)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
72 result(s) found for: Frailty.
Displaying page 1 of 4.
| EudraCT Number: 2021-001645-12 | Sponsor Protocol Number: ALPHA2PREVENT | Start Date*: 2021-06-28 |
| Sponsor Name:Oslo University Hospital | ||
| Full Title: Alpha 2 adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): randomised controlled trial. | ||
| Medical condition: Postoperative delirium and cognitive decline in male and female participants aged 70+ scheduled for open heart surgery | ||
| Disease: | ||
| Population Age: Elderly | Gender: Male, Female | |
| Trial protocol: NO (Trial now transitioned) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2020-003620-16 | Sponsor Protocol Number: IIV-465 | Start Date*: 2021-05-27 |
| Sponsor Name:National Institute of Health and the Environment | ||
| Full Title: Vaccine immunogenicity in Dutch frail versus non-frail older individuals (participating in the Doetinchem Cohort study) | ||
| Medical condition: Older adults 73-79 years of age, birth cohorts year 1941-1947, still participating in round 6 of the Doetinchem Cohort Study. | ||
| Disease: | ||
| Population Age: Elderly | Gender: Male, Female | |
| Trial protocol: NL (Completed) | ||
| Trial results: View results | ||
| EudraCT Number: 2021-002363-22 | Sponsor Protocol Number: IIV-482 | Start Date*: 2021-05-27 |
| Sponsor Name:National Institute for Public Health and the Environment | ||
| Full Title: Vaccination of older persons against Sars-Cov-2 and cellular immunogenicity for long term protection (participating in the Doetinchem Cohort Study) | ||
| Medical condition: SARS-CoV-19, frailty | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: NL (Completed) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2016-004236-38 | Sponsor Protocol Number: 12250 | Start Date*: 2017-01-24 |
| Sponsor Name:University of Oxford | ||
| Full Title: OPtimising Treatment for MIld Systolic hypertension in the Elderly: a randomised controlled trial | ||
| Medical condition: Hypertension | ||
| Disease: | ||
| Population Age: Elderly | Gender: Male, Female | |
| Trial protocol: GB (GB - no longer in EU/EEA) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2021-001976-40 | Sponsor Protocol Number: IIV-479 | Start Date*: 2021-05-20 |
| Sponsor Name:National Institute for Public Health and the Environment | ||
| Full Title: Monitoring immunogenicity of SARS-Cov-2 vaccination in Dutch middle-aged and older individuals (participating in the Doetinchem Cohort Study) | ||
| Medical condition: SARS-CoV-19, frailty | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: NL (Completed) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2017-002738-22 | Sponsor Protocol Number: 62388 | Start Date*: 2018-03-02 | |||||||||||
| Sponsor Name:Princess Máxima Center of Pediatric Oncology | |||||||||||||
| Full Title: Double blind placebo controlled randomized intervention study to validate the beneficial effect of hydrocortisone on dexamethasone-induced neurobehavioral side effects in pediatric acute lymphoblas... | |||||||||||||
| Medical condition: Acute lymphoblastic leukemia | |||||||||||||
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| Population Age: Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||
| Trial protocol: NL (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2018-003703-19 | Sponsor Protocol Number: 18-002 | Start Date*: 2020-04-20 |
| Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty | ||
| Full Title: The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Randomized Trial | ||
| Medical condition: Nutritionally high-risk critically ill mechanically ventilated patients. In this sub-study, eligible and enrolled patients randomized to the high protein dose group will achieve its protein goals b... | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: DE (Prematurely Ended) | ||
| Trial results: View results | ||
| EudraCT Number: 2018-003590-10 | Sponsor Protocol Number: HM19/123658 | Start Date*: 2019-10-30 | ||||||||||||||||||||||||||
| Sponsor Name:University of Leeds | ||||||||||||||||||||||||||||
| Full Title: Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma: A phase III trial to compare standard and frailty-adjusted induction therapy with ixazomib, lena... | ||||||||||||||||||||||||||||
| Medical condition: Newly diagnosed multiple myeloma | ||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
| Trial protocol: GB (GB - no longer in EU/EEA) | ||||||||||||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||||||||||||
| EudraCT Number: 2022-001283-10 | Sponsor Protocol Number: NL80929.091.22 | Start Date*: 2022-06-28 |
| Sponsor Name:Radboud University Medical Center | ||
| Full Title: The effects of medication induced blood pressure reduction on cerebral hemodynamics in hypertensive frail elderly | ||
| Medical condition: Hypertension | ||
| Disease: | ||
| Population Age: Elderly | Gender: Male, Female | |
| Trial protocol: NL (Completed) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2011-000919-22 | Sponsor Protocol Number: OMB114578 | Start Date*: 2011-09-14 | |||||||||||
| Sponsor Name:University of Liverpool [...] | |||||||||||||
| Full Title: RIAltO: A Randomised Investigation of Alternative Ofatumumab-containing regimens in less fit patients with CLL | |||||||||||||
| Medical condition: Chronic Lymphocytic Leukaemia | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2018-003194-10 | Sponsor Protocol Number: 789456 | Start Date*: 2019-03-19 |
| Sponsor Name:UMCG | ||
| Full Title: OPen label multicenter randomized Trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de no... | ||
| Medical condition: de novo renal transplantation in elderly patients. | ||
| Disease: | ||
| Population Age: Elderly | Gender: Male, Female | |
| Trial protocol: NL (Trial now transitioned) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2019-004586-41 | Sponsor Protocol Number: UOL0753 | Start Date*: 2020-06-01 | |||||||||||
| Sponsor Name:University of Leicester | |||||||||||||
| Full Title: Impact of exercise training in combination with dapagliflozin on physical function in adults with type 2 diabetes mellitus: A Randomised controlled trial | |||||||||||||
| Medical condition: Frailty and the preceding 'pre-frail' state in patients with type 2 Diabetes Mellitus. | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2016-004555-79 | Sponsor Protocol Number: 16-115 | Start Date*: 2017-08-08 |
| Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty | ||
| Full Title: Impact of preoperative midazolam on outcome of elderly patients: a multicenter randomised controlled trial | ||
| Medical condition: Under investigation are elderly patients (≥65 years of age) undergoing each kind of surgery with planned general or combined regional and general anaesthesia. Primary, we will investigate the posto... | ||
| Disease: | ||
| Population Age: Elderly | Gender: Male, Female | |
| Trial protocol: DE (Completed) | ||
| Trial results: View results | ||
| EudraCT Number: 2005-001007-18 | Sponsor Protocol Number: 2989 | Start Date*: 2005-06-03 |
| Sponsor Name:Royal Victoria Infirmary | ||
| Full Title: Reversal of warfarin anticoagulation with oral vitamin K: towards a better management of over-anticoagulation | ||
| Medical condition: Patients with thromboembolic disorders are anticogulated with warfarin. However excessive over-anticoagulation can increase the patient risk of bleeding. Oral vitamin K is routinely used for revers... | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: GB (Completed) | ||
| Trial results: View results | ||
| EudraCT Number: 2016-000087-42 | Sponsor Protocol Number: TAISTR_2016 | Start Date*: 2016-05-11 |
| Sponsor Name:University College Dublin | ||
| Full Title: A multicentre, prospective, single arm, open-label 96 week observational trial of the tolerability, adherence and efficacy of a dolutegravir/abacavir/lamivudine single tablet regimen in HIV-1 antib... | ||
| Medical condition: Human Immunodeficiency Virus (HIV) infection | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: IE (Prematurely Ended) ES (Prematurely Ended) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2021-003299-15 | Sponsor Protocol Number: METFORAGING | Start Date*: 2021-10-19 |
| Sponsor Name:Fundación para la Investigación Biomédica del Hospital La Paz | ||
| Full Title: A double blinded, phase II, placebo controlled, single center randomized clinical trial to evaluate metformin compared with placebo for reversal of accelerated biological aging in persons living wi... | ||
| Medical condition: Patients with HIV and accelerated biological aging | ||
| Disease: | ||
| Population Age: Adults, Elderly | Gender: Male, Female | |
| Trial protocol: ES (Ongoing) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2015-003032-13 | Sponsor Protocol Number: DF-07 | Start Date*: 2016-09-15 | |||||||||||
| Sponsor Name:A.O.U. Università degli Studi della Campania "Luigi Vanvitelli" | |||||||||||||
| Full Title: A 16 week PILOT Study to determine the Frequency of Suphonylurea-Associated Hypoglycaemia in older moderately frail patients with type 2 diabetes mellitus poorly controlled on metformin: an open la... | |||||||||||||
| Medical condition: Type 2 Diabetes Mellitus | |||||||||||||
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| Population Age: Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: IT (Prematurely Ended) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2017-000329-11 | Sponsor Protocol Number: Elderly | Start Date*: 2018-05-02 | ||||||||||||||||
| Sponsor Name:Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | ||||||||||||||||||
| Full Title: Aflibercept and 5-FU vs. FOLFOX as 1st line treatment for elderly or frail elderly patients with metastatic colorectal cancer | ||||||||||||||||||
| Medical condition: metastatic colorectal cancer | ||||||||||||||||||
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| Population Age: Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DE (Completed) | ||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||
| EudraCT Number: 2006-001643-63 | Sponsor Protocol Number: 2006001 | Start Date*: 2006-06-22 |
| Sponsor Name:GERENCIA DE ATENCIÓN PRIMARIA | ||
| Full Title: PREVENCIÓN DE CAÍDAS EN ANCIANOS MEDIANTE LA ADMINISTRACIÓN DE CALCIO Y VITAMINA D. ESTUDIO DE INTERVENCIÓN | ||
| Medical condition: OBJECTIVE. To evaluate the effectiveness of calcium and vitamin D supplementation (from November to April in a two year period) to improve the muscle function and strength in 65 years and older and... | ||
| Disease: | ||
| Population Age: Elderly | Gender: Male, Female | |
| Trial protocol: ES (Ongoing) | ||
| Trial results: (No results available) | ||
| EudraCT Number: 2011-005534-19 | Sponsor Protocol Number: FRIA_FATSURG_1 | Start Date*: 2012-01-31 |
| Sponsor Name:Vrije Universiteit Brussel | ||
| Full Title: The effect of peri-operative anti-inflammatory treatment on postoperative muscle weakness and muscle fatigue in elderly elective surgery patients: a double blinded randomized placebo-controlled trial. | ||
| Medical condition: Post-operative muscle weakness, fatigue and inflammation. | ||
| Disease: | ||
| Population Age: Elderly | Gender: Male, Female | |
| Trial protocol: BE (Completed) | ||
| Trial results: (No results available) | ||
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