Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Glaucoma surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    25 result(s) found for: Glaucoma surgery. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2013-000395-15 Sponsor Protocol Number: MATR1001 Start Date*: 2016-03-10
    Sponsor Name:Moorfields Eye Hospital NHS Foundation Trust
    Full Title: The use of bevacizumab as a modulator of wound healing following trabeculectomy surgery: A Single Centre Randomised Controlled Phase III Pilot Study.
    Medical condition: Primary Open Angle Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    18.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019975-30 Sponsor Protocol Number: 35131 Start Date*: 2010-08-24
    Sponsor Name:University Medical Center, Johannes Gutenberg-University Mainz
    Full Title: Investigation of the efficacy and safety of preoperative IOP reduction with preservative-free COSOPT-S® (dorzolamide/timolol, MSD) eye drops versus oral acetazolamide and dexamethasone eye drops an...
    Medical condition: Patients with glaucoma requiring trabeculectomy (filtration surgery)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10018304 Glaucoma LLT
    12.1 10050156 Glaucoma surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001727-39 Sponsor Protocol Number: POP03 Start Date*: 2018-10-16
    Sponsor Name:Polpharma S.A.
    Full Title: A PHASE III, MULTICENTRE, RANDOMISED, INVESTIGATOR-MASKED, CROSSOVER, COMPARATIVE, NON-INFERIORITY TRIAL EVALUATING THE EFFICACY AND TOLERABILITY OF GENERIC LATANOPROST 0.05 MG/ML EYE DROPS SOLUTIO...
    Medical condition: Ocular hypertension and open angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-001156-12 Sponsor Protocol Number: 73652 Start Date*: 2006-04-04
    Sponsor Name:Santen Oy
    Full Title: Corneal penetration of timolol into the human aqueous humor after administration of 0.1% Timosan eye gel or 0.5% timolol eye drops
    Medical condition: Pharmacokinetic study of glaucoma drug in cataract patients
    Disease: Version SOC Term Classification Code Term Level
    8.1 10018304 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2009-017859-98 Sponsor Protocol Number: PRM151B-21GL Start Date*: 2010-04-09
    Sponsor Name:Promedior Inc
    Full Title: A Randomized, Double-Masked, Placebo-Controlled Study of PRM-151 in the Prevention of Postoperative Scarring in Glaucoma Patients Following Primary Trabeculectomy
    Medical condition: PRM-151, a novel agent, is being developed for potential therapeutic uses to prevent, treat and reduce fibrosis. This study will investigate the ability of PRM-151 to prevent scarring post glaucoma...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10015919 - Eye disorders 10018304 Glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) BE (Prematurely Ended) NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-004841-34 Sponsor Protocol Number: 101219 Start Date*: 2020-08-24
    Sponsor Name:Mika Harju
    Full Title: Selective laser trabeculoplasty versus eye drops for first line treatment of exfoliation ocular hypertension or glaucoma: a randomised clinical trial
    Medical condition: Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-004836-93 Sponsor Protocol Number: 012603SA Start Date*: 2021-10-20
    Sponsor Name:SANTEN INCORPORATED
    Full Title: An Exploratory Study to Assess the 24-hour Intraocular Pressure (IOP) Lowering Characteristics, Duration of Action and Safety of DE-126 ophthalmic solution 0.002% versus Latanoprost ophthalmic solu...
    Medical condition: Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2013-000581-10 Sponsor Protocol Number: 12OY006 Start Date*: 2013-07-25
    Sponsor Name:Nottingham University NHS Trust
    Full Title: Evaluation of inflammatory markers in patients on topical anti-glaucoma drop therapy; a comparative trial of preserved and non-preserved primary medical treatment (eye drops) in patients with glauc...
    Medical condition: Glaucoma is the condition that is being treated by these eye drops - however the study is aimed at measuring the amount of inflammation that develops on the surface of the eye when these drops are ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-001855-10 Sponsor Protocol Number: SNAP1 Start Date*: 2019-01-22
    Sponsor Name:Department of Ophtalmology, Rigshospitalet-Glostrup
    Full Title: Steroids and Non-steroidal Anti-inflammatory drugs in the Postoperative regime after trabeculectomy. An investigator-initiated randomized study (The SNAP study)
    Medical condition: Medically uncontrolled glaucoma that requires filtration surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10018326 Glaucoma NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-001093-16 Sponsor Protocol Number: DX203 Start Date*: 2013-07-16
    Sponsor Name:Oculis ehf.
    Full Title: Comparison of non-MMC trabeculectomy and dexamethasone nanoparticles eye drops with MMC trabeculectomy and Maxidex®
    Medical condition: Anti-inflammatory treatment post trabeculectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IS (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000946-69 Sponsor Protocol Number: AZ07 Start Date*: 2016-07-05
    Sponsor Name:AZAD Pharma AG
    Full Title: A PHASE III, MULTICENTRE, RANDOMISED, INVESTIGATOR-MASKED, CROSS- OVER, COMPARATIVE CLINICAL TRIAL EVALUATING THE EFFICACY AND SAFETY OF THE GENERIC BRINZOLAMIDE 10 MG/ML + TIMOLOL 5 MG/ML EYE DROP...
    Medical condition: Decrease of intraocular pressure (IOP) in adult patients with open-angle glaucoma or ocular hypertension for whom monotherapy provides insufficient IOP reduction
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    19.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) AT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2004-004862-33 Sponsor Protocol Number: BCBe/04/Neb-Gla/081 Start Date*: 2006-05-23
    Sponsor Name:Berlin-Chemie Menarini
    Full Title: INFLUENCE OF NEBIVOLOL ON OCULAR PERFUSION IN PATIENTS WITH ARTERIAL HYPERTENSION AND GLAUCOMA A mono-center, active-substance controlled, randomized, double-blind, prospective phase IV parallel-g...
    Medical condition: Arterial hypertension and glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024100-10 Sponsor Protocol Number: OZR-2010-17 Start Date*: 2011-03-28
    Sponsor Name:The Rotterdam Eye Hospital
    Full Title: Clonidine as an adjuvant to prolong local anaesthesia in ophthalmic surgery with cryocoagulation. A randomized, controlled, patient-masked trial.
    Medical condition: - Rhegmatogenous retinal detachment requiring cryocoagulation and episcleral explant. - Glaucoma requiring cryocoagulation of the ciliary body.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-022791-31 Sponsor Protocol Number: D01092010AZNTG Start Date*: Information not available in EudraCT
    Sponsor Name:University Erlangen-Nuremberg
    Full Title: Contrast sensitivity of patients with normal tension glaucoma by application of Azarga®
    Medical condition: The effect of AZARGA(R) on the central and spacial-temporal contrast sensitivity of patients with normal tension glaucoma will be examined. Healthy controls are required to prove the disease specif...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019279 Heart failure LLT
    12.1 10003555 Asthma bronchial LLT
    12.1 10021005 Hypoglycemia LLT
    12.1 10000456 Acid base balance LLT
    12.1 10054844 Anaphylactic reaction to drug LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001991-37 Sponsor Protocol Number: WICL1001 Start Date*: 2004-11-18
    Sponsor Name:Moorfields Eye Hospital
    Full Title: A pilot study investigating the effects of a combination of local and systemic anti-inflammatory adjuncts in patients undergoing vitrectomy and silicone oil for established Proliferative Vitreoreti...
    Medical condition: Proliferative Vitreoretinopathy This is a scarring process that occurs in patients who have developed a retinal detachment. It is the primary cause of failure in retinal detachment surgery and oc...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-003692-12 Sponsor Protocol Number: AZ02 Start Date*: 2012-05-09
    Sponsor Name:AZAD Pharma AG
    Full Title: A phase III , multicentre, randomised, investigator-masked, cross-over, comparative efficacy study of a generic Brinzolamide 10 mg/ml ophthalmic suspension (Azad Pharma AG) and Brinzolamide 10 mg/m...
    Medical condition: Patients suffering from open angle glaucoma and ocular hypertension with an elevated IOP, higher than 22mmHg and and lower or equal than 35 mmHg
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2014-000540-15 Sponsor Protocol Number: SPON1266-14 Start Date*: 2014-05-01
    Sponsor Name:Cardiff University
    Full Title: Prostaglandin F2-alpha eye drops (Bimatoprost) in thyroid eye disease: a randomised controlled double blind crossover trial
    Medical condition: Graves' ophthalmopathy
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004853 10057889 Graves' ophthalmopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-002738-36 Sponsor Protocol Number: AKST4290-205 Start Date*: 2019-10-30
    Sponsor Name:Alkahest, Inc.
    Full Title: A Double-Masked, Placebo-Controlled, Dose Ranging Study to Evaluate the Efficacy of Oral AKST4290 with Loading Doses of Aflibercept in Patients with Newly Diagnosed Neovascular Age-Related Macular ...
    Medical condition: Newly Diagnosed Neovascular Age-Related Macular Degeneration
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10075568 Wet age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-002947-27 Sponsor Protocol Number: SIMCODE Start Date*: 2020-01-22
    Sponsor Name:Charité – Universitätsmedizin Berlin
    Full Title: Simvastatin add-on to Escitalopram in patients with comorbid obesity and major depression: A multicenter, randomized, double-blind, placebo-controlled trial
    Medical condition: Patients with comorbid obesity (body mass index ≥ 30) and major depression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001823-30 Sponsor Protocol Number: 043/SI Start Date*: 2017-06-12
    Sponsor Name:SIFI SpA
    Full Title: Randomized, Assessor-Masked, Active-Controlled, Phase 3 Study to Evaluate Efficacy, Safety and Tolerability of 0.08% Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Comparison with 0.02% ...
    Medical condition: Acanthamoeba keratitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10069408 Acanthamoeba keratitis PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) PL (Completed) IT (Completed)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Tue Jul 01 23:54:06 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA