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Clinical trials for Lactic acidosis

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    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    24 result(s) found for: Lactic acidosis. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2009-013115-35 Sponsor Protocol Number: MP4OX-09-TRA-204 Start Date*: 2009-11-05
    Sponsor Name:Sangart, Inc.
    Full Title: A multi-center, randomized, double-blind, controlled dose-finding study to evaluate the safety and efficacy of MP4OX treatment plus standard of care in severely injured trauma patients with lactic ...
    Medical condition: Trauma with lactic acidosis due to hemorrhagic shock
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023676 Lactic acidosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002579-37 Sponsor Protocol Number: Metformina-Bone Start Date*: 2020-11-18
    Sponsor Name:ISTITUTO ORTOPEDICO RIZZOLI
    Full Title: Metformin as maintenance therapy in bone sarcomas at high risk of relapse
    Medical condition: Osteosarcoma and Ewing's Sarcoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10023676 Lactic acidosis PT
    20.1 10027433 - Metabolism and nutrition disorders 10000491 Acidosis lactic LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-023129-39 Sponsor Protocol Number: MP4OX-10-TRA-205 Start Date*: 2011-03-22
    Sponsor Name:Sangart, Inc.
    Full Title: Estudio multicéntrico, aleatorizado, en doble ciego y controlado, para evaluar la seguridad y la eficacia del tratamiento con MP4OX, añadido al tratamiento habitual, en pacientes con traumatismo se...
    Medical condition: Pacientes con traumatismo severo y acidosis láctica por shock hemorrágico.//Severely injured trauma patients with lactic acidosis due to hemorrhagic shock.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10050841 Hemorrhagic shock LLT
    12.1 10023676 Lactic acidosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) AT (Completed) DE (Completed) GB (Completed) NO (Completed) IT (Ongoing) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001094-25 Sponsor Protocol Number: PHEMI Start Date*: 2019-09-12
    Sponsor Name:FONDAZIONE IRCCS ISTITUTO NEUROLOGICO CARLO BESTA
    Full Title: Phenylbutyrate Therapy in Mitochondrial Disease with lactic acidosis: an opel label clinical trial in MELAS and PHD deficiency patients
    Medical condition: Melas Syndrome and PDH deficency enchephalopathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10053872 MELAS syndrome PT
    20.0 10010331 - Congenital, familial and genetic disorders 10053872 MELAS syndrome PT
    20.0 10010331 - Congenital, familial and genetic disorders 10062950 Leigh syndrome LLT
    Population Age: Children, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006948-65 Sponsor Protocol Number: Version 4 Start Date*: 2007-11-29
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: The effect of acidosis correction and exercise on tissue wasting and immune function in renal patients
    Medical condition: Chronic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-001550-34 Sponsor Protocol Number: TIGEM2-PDH Start Date*: Information not available in EudraCT
    Sponsor Name:FONDAZIONE TELETHON
    Full Title: Studio clinico pilota per valutare l’efficacia della terapia con fenilbutirrato in pazienti affetti da deficit di piruvato deidrogenasi
    Medical condition: La Sperimentazione verrà eseguita su pazienti affetti da difetto dell’enzima piruvato deidrogenasi.I pazienti affetti da questa malattia manifestano aumento dei livelli di lattato nel sangue e nell...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10058097 Metabolic disorder PT
    20.1 10027433 - Metabolism and nutrition disorders 10000491 Acidosis lactic LLT
    20.0 10022891 - Investigations 10037677 Pyruvate LLT
    20.0 10022891 - Investigations 10023660 Lactate increased LLT
    20.0 10022891 - Investigations 10057975 Lactate pyruvate ratio PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-004384-29 Sponsor Protocol Number: Levosepsis1 Start Date*: 2005-05-23
    Sponsor Name:Dr GED DEMPSEY, University Hospital Aintree
    Full Title: Double blind randomised controlled trial of Levosimendan versus Dopexamine in septic shock
    Medical condition: Septic Shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000818-78 Sponsor Protocol Number: 7-010-MR Start Date*: 2008-09-25
    Sponsor Name:POLICLINICO SAN DONATO IRCSS
    Full Title: Efficacy of fenoldopam mesilate in controlling splanchnic ischemia during cardiopulmonary bypass
    Medical condition: Patients to be submitted to cardiac surgery with expected prolonged CPB time
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048935 Open heart surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-001487-30 Sponsor Protocol Number: MIMET-2019 Start Date*: 2020-06-22
    Sponsor Name:Karolinska Institutet
    Full Title: The Myocardial Infarction and new treatment with Metformin study (MIMET) – a registry-based randomised controlled multicenter trial to study metformin and the prevention of cardiovascular events in...
    Medical condition: The study will investigate metformin and the prevention of cardiovascular events in patients with acute myocardial infarction and newly detected prediabetes.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004080-70 Sponsor Protocol Number: Start Date*: 2011-11-17
    Sponsor Name:Med. Univ. Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
    Full Title: Preoperative parenteral thiamine supplementation in patients undergoing heart surgery – a pilot study
    Medical condition: The objective of this study is to determine the prevalence of thiamine deficiency (TD) in patients with heart surgery, to examine the association between thiamine levels and lactic acidosis and to ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004245-41 Sponsor Protocol Number: Nill Start Date*: 2012-11-14
    Sponsor Name:Hywel Dda Health Board
    Full Title: Safety, Tolerability and Effectiveness of Glocophage®SR in patients with type-2 Diabetes and Chronic Kidney Disease (eGFR 30 to 45mL/minute/1.73m2)
    Medical condition: Type-2 Diabetes with chronic kidney disease (eGFR 30 to 45)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    20.0 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-001696-79 Sponsor Protocol Number: KH176-201 Start Date*: 2016-09-06
    Sponsor Name:Khondrion BV
    Full Title: A double-blind, randomized, placebo-controlled, single-center, two-way cross-over study with KH176 in patients with the mitochondrial DNA tRNALeu(UUR) m.3243A>G mutation and clinical signs of mitoc...
    Medical condition: Inherited mitochondrial disease, including MELAS (mitochondrial Encephalopathy Lactic Acidosis and Stroke like episodes) and MIDD (Maternally Inherited Diabetes and Deafness)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002118-37 Sponsor Protocol Number: HTAJ-TRANEX-2019-01 Start Date*: 2021-06-17
    Sponsor Name:Rafael Blancas-Gómez Casero
    Full Title: MULTICENTER, DOUBLE BLIND CLINICAL TRIAL TO EVALUATE THE ANTIHEMORRAGIC EFFECT OF THE TOPICAL TRANEXAMIC ACID DURING PACEMAKER IN ANTICOAGULATED PATIENTS
    Medical condition: Pacemaker implant for anticoagulated patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001027-11 Sponsor Protocol Number: AS07/1104-001 Start Date*: 2005-06-03
    Sponsor Name:University Hospitals Coventry and Warwickshire NHS Trust
    Full Title: Diabetes in the Very Elderly Trial
    Medical condition: Type 2 Diabetes Mellitus
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-003551-22 Sponsor Protocol Number: 55029 Start Date*: 2016-12-28
    Sponsor Name:Erasmus MC - Sophia Children's Hospital
    Full Title: STATIC IV: Efficacy of a loading dose of intravenous salbutamol in patients admitted to a PICU for severe acute asthma
    Medical condition: Severe acute (viral) wheeze and severe acute asthma
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10047921 Wheeze LLT
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10041961 Status asthmaticus PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002996-27 Sponsor Protocol Number: 13CC34 Start Date*: 2015-02-02
    Sponsor Name:Great Ormond Street Hospital For Children NHS Foundation Trust
    Full Title: Optimising effectiveness and minimising toxicity of intravenous salbutamol in children with acute asthma
    Medical condition: The mainstay of asthma treatment worldwide are β2-agonists and steroids. Current management of childhood acute asthma is based on British Thoracic Society guidelines, which recommend IVS as second ...
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-000375-39 Sponsor Protocol Number: PTC743-CNS-005-LSEP Start Date*: 2022-12-07
    Sponsor Name:PTC THERAPEUTICS INC.
    Full Title: AN OPEN-LABEL, SAFETY STUDY FOR PREVIOUSLY TREATED VATIQUINONE (PTC743) SUBJECTS WITH INHERITED MITOCHONDRIAL DISEASE
    Medical condition: Inherited mitochondrial disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10052637 Genetic mitochondrial abnormalities NEC HLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended) ES (Prematurely Ended) FR (Prematurely Ended) SE (Prematurely Ended) PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-002303-14 Sponsor Protocol Number: A5951110 Start Date*: 2008-12-17
    Sponsor Name:Pfizer Inc. 235 East 42nd Street, New York, NY10017, USA
    Full Title: PROSPECTIVE STUDY OF OPHTHALMOLOGIC FUNCTION IN PATIENTS RECEIVING LINEZOLID FOR TWO MONTHS OR GREATER
    Medical condition: This study is designed to understand the effects of linezolid on the optic nerve by observing and following patients who have been treated with linezolid for two months or longer for the developmen...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10061323 Optic neuropathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-001057-26 Sponsor Protocol Number: IRFM-7468 Start Date*: 2018-07-19
    Sponsor Name:IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
    Full Title: Management of the patient with heart failure and diabetes: may insulin be a problem? A pilot randomized clinical study (Insulin-HF).
    Medical condition: Heart failure and diabetes
    Disease: Version SOC Term Classification Code Term Level
    21.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    20.1 100000004849 10007555 Cardiac failure (NOS) LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-005537-35 Sponsor Protocol Number: E5564-G000-301 Start Date*: 2006-08-30
    Sponsor Name:Eisai Limited
    Full Title: ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients with Severe Sepsis
    Medical condition: Severe Sepsis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10040047 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) NL (Completed) AT (Completed) CZ (Completed) ES (Completed) DE (Completed) PT (Prematurely Ended) IT (Prematurely Ended) GB (Completed)
    Trial results: View results
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