- Trials with a EudraCT protocol (190)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
190 result(s) found for: Large cell carcinoma.
Displaying page 1 of 10.
| EudraCT Number: 2006-003333-33 | Sponsor Protocol Number: JJ0606 | Start Date*: 2007-03-13 | |||||||||||
| Sponsor Name:Cardiff and Vale NHS Trust | |||||||||||||
| Full Title: A randomised controlled, open label, phase II pilot study comparing the toxicity of rituximab plus CHOP chemotherapy with rituximab plus CHOP chemotherapy and bortezomib in adults with newly diagno... | |||||||||||||
| Medical condition: Diffuse large B-cell lymphoma | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2013-004014-17 | Sponsor Protocol Number: FIL_GA101_DHAP | Start Date*: 2014-08-04 | |||||||||||
| Sponsor Name:Fondazione Italiana Linfomi ONLUS | |||||||||||||
| Full Title: Phase II study with Ga101-DHAP as induction therapy in relapsed/refractory Diffuse Large B-cell Lymphoma (DLBCL) patients before High-Dose chemotherapy BEAM with autologous stem cell transplantatio... | |||||||||||||
| Medical condition: Young patients with DLBCL who failed or relapsed after one previous chemotherapy regimen. | |||||||||||||
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| Population Age: Adults | Gender: Male, Female | ||||||||||||
| Trial protocol: IT (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2017-005137-23 | Sponsor Protocol Number: FIL_RI-CHOP | Start Date*: 2019-02-07 | |||||||||||
| Sponsor Name:FONDAZIONE ITALIANA LINFOMI ONLUS | |||||||||||||
| Full Title: Phase II multicenter single arm study to evaluate the efficacy and safety of ibrutinib in combination to rituximab-CHOP followed by ibrutinib maintenance in untreated patients with Activated-B-Cell... | |||||||||||||
| Medical condition: Activated-B-Cell Lymphoma (ABC)-DLBCL at intermediate-high and high risk (IPI =2) | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: IT (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2017-000241-49 | Sponsor Protocol Number: CNIR178X2201 | Start Date*: 2017-12-05 | ||||||||||||||||
| Sponsor Name:Novartis Pharma AG | ||||||||||||||||||
| Full Title: A Phase 2, multi-center, open label study of NIR178 in combination with PDR001 in patients with selected advanced solid tumors and non-Hodgkin lymphoma | ||||||||||||||||||
| Medical condition: Advanced solid tumors and non-Hodgkin lymphoma | ||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
| Trial protocol: DE (Prematurely Ended) BE (Completed) CZ (Completed) AT (Prematurely Ended) ES (Prematurely Ended) NL (Completed) FR (Prematurely Ended) IT (Prematurely Ended) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2018-001585-42 | Sponsor Protocol Number: CA209-8KX | Start Date*: 2019-01-09 | ||||||||||||||||||||||||||||||||||||
| Sponsor Name:Bristol-Myers Squibb International Corporation | ||||||||||||||||||||||||||||||||||||||
| Full Title: Phase I/II pharmacokinetic multi-tumor study of subcutaneous formulation of nivolumab monotherapy | ||||||||||||||||||||||||||||||||||||||
| Medical condition: The study population will include participants with 1 of the following advanced or metastatic tumors approved for treatment with nivolumab monotherapy: non-small cell lung cancer (NSCLC); renal ce... | ||||||||||||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||
| Trial protocol: PL (Ongoing) GB (GB - no longer in EU/EEA) ES (Ongoing) NL (Trial now transitioned) IT (Trial now transitioned) | ||||||||||||||||||||||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||||||||||||||||||||||
| EudraCT Number: 2015-001111-12 | Sponsor Protocol Number: 1367.1 | Start Date*: 2015-06-12 | ||||||||||||||||||||||||||||||||||||
| Sponsor Name:SCS Boehringer Ingelheim Comm.V | ||||||||||||||||||||||||||||||||||||||
| Full Title: An open label, Phase Ia/Ib dose finding study with BI 894999 orally administered once a day in patients with advanced malignancies, with repeated administration in patients with clinical benefit | ||||||||||||||||||||||||||||||||||||||
| Medical condition: Advanced, unresectable and/or metastatic solid tumours, which have failed with conventional treatment or for which no therapy of proven efficacy exists, or in patients who are not amenable to stand... | ||||||||||||||||||||||||||||||||||||||
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| Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||
| Trial protocol: BE (Completed) DE (Completed) DK (Prematurely Ended) | ||||||||||||||||||||||||||||||||||||||
| Trial results: View results | ||||||||||||||||||||||||||||||||||||||
| EudraCT Number: 2021-006196-42 | Sponsor Protocol Number: CJDQ443E12101 | Start Date*: 2022-08-16 | ||||||||||||||||||||||||||
| Sponsor Name:Novartis Pharma AG | ||||||||||||||||||||||||||||
| Full Title: KontRASt-03: A Phase Ib/II, multicenter, open-label platform study of JDQ443 with select combinations in patients with advanced solid tumors harboring the KRAS G12C mutation | ||||||||||||||||||||||||||||
| Medical condition: adult patients with advanced (metastatic or unresectable) KRAS G12C mutant solid tumors | ||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
| Trial protocol: BE (Trial now transitioned) IT (Trial now transitioned) ES (Ongoing) | ||||||||||||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||||||||||||
| EudraCT Number: 2011-003958-85 | Sponsor Protocol Number: IMM-101-007 | Start Date*: 2012-02-03 | |||||||||||
| Sponsor Name:Immodulon Therapeutics Ltd | |||||||||||||
| Full Title: A Phase II, Single Arm, Investigative Study of IMM-101 in Combination with Radiation Induced Tumour Necrosis in Patients with Previously Treated Colorectal Cancer | |||||||||||||
| Medical condition: Metastatic colorectal cancer | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: GB (Completed) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2022-002805-90 | Sponsor Protocol Number: EOCRC2-22 | Start Date*: 2023-02-08 | ||||||||||||||||||||||||||
| Sponsor Name:Enterome SA | ||||||||||||||||||||||||||||
| Full Title: A global multicenter phase 1/2 trial of EO4010, a novel microbial-derived peptide therapeutic vaccine, in combination with nivolumab, for treatment of patients with previously treated metastatic co... | ||||||||||||||||||||||||||||
| Medical condition: Patients with unresectable, previously treated locally advanced or metastatic colorectal carcinoma. | ||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
| Trial protocol: FR (Trial now transitioned) ES (Ongoing) | ||||||||||||||||||||||||||||
| Trial results: (No results available) | ||||||||||||||||||||||||||||
| EudraCT Number: 2007-003560-21 | Sponsor Protocol Number: REAL 07 CC5013 STUDY ID LR-CHOP21 | Start Date*: 2007-09-20 | |||||||||||
| Sponsor Name:GIMURELL | |||||||||||||
| Full Title: Prospective multicenter phase I-II pilot trial to evaluate efficacy and safety of treatment with Lenalidomide plus R-CHOP21 (LR-CHOP21) for elderly patients with untreated Diffuse Large B-Cell Lymp... | |||||||||||||
| Medical condition: patient with BDLCL elderly untreated | |||||||||||||
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| Population Age: Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: IT (Completed) DE (Ongoing) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2007-003844-31 | Sponsor Protocol Number: H6Q-MC-S064 | Start Date*: 2007-11-28 | |||||||||||
| Sponsor Name:Eli Lilly and Company limited | |||||||||||||
| Full Title: A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Study of Enzastaurin with 5 FU/LV plus Bevacizumab as Maintenance Regimen Following First Line Therapy for Metastatic Colorectal Cancer | |||||||||||||
| Medical condition: Locally advanced or metastatic Colorectal Cancer | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: DE (Prematurely Ended) FR (Completed) IT (Prematurely Ended) AT (Prematurely Ended) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2016-004989-25 | Sponsor Protocol Number: INCAGN1876-201 | Start Date*: 2017-09-28 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sponsor Name:Incyte Biosciences International Sàrl | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Title: A Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 in Combination With Immune Therapies in Subjects With Advanced or Metastatic Malignancies. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Medical condition: Phase 1: advanced or metastatic cervical cancer, endometrial cancer, gastric cancer, hepatocellular carcinoma, melanoma (mucosal or cutaneous), Merkel cell carcinoma, mesothelioma, MSI-H colorectal... | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Trial protocol: ES (Completed) BE (Completed) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| EudraCT Number: 2005-003479-19 | Sponsor Protocol Number: UCL/05/134 | Start Date*: 2006-02-02 | ||||||||||||||||
| Sponsor Name:University College London | ||||||||||||||||||
| Full Title: A Phase II Single Arm Study of the use of CODOX-M/IVAC with Rituximab (R-CODOX-M/IVAC) in the treatment of patients with Diffuse Large B-Cell Lymphoma (DLBCL) or Burkitt's Lymphoma (BL) of Internat... | ||||||||||||||||||
| Medical condition: Diffuse large B-cell lymphoma Burkitt's lymphoma | ||||||||||||||||||
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| Population Age: Adults | Gender: Male, Female | |||||||||||||||||
| Trial protocol: GB (Completed) | ||||||||||||||||||
| Trial results: View results | ||||||||||||||||||
| EudraCT Number: 2018-001456-34 | Sponsor Protocol Number: CTMX-M-2029-001 | Start Date*: 2019-01-17 | |||||||||||||||||||||||||||||||
| Sponsor Name:CytomX Therapeutics, Inc. | |||||||||||||||||||||||||||||||||
| Full Title: A Phase 1-2, First-in-Human Study of CX-2029 in Adults with Metastatic or Locally Advanced Unresectable Solid Tumors or Diffuse Large B-cell Lymphomas | |||||||||||||||||||||||||||||||||
| Medical condition: Metastatic or locally advanced unresectable solid tumor or diffuse large B-cell lymphoma | |||||||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||
| Trial protocol: ES (Ongoing) GB (GB - no longer in EU/EEA) | |||||||||||||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||||||||||||
| EudraCT Number: 2016-005039-34 | Sponsor Protocol Number: ASTX660-01 | Start Date*: 2018-02-05 | |||||||||||||||||||||||||||||||
| Sponsor Name:Astex Pharmaceuticals, Inc. | |||||||||||||||||||||||||||||||||
| Full Title: Phase 1-2 Study of the Safety, Pharmacokinetics, and Preliminary Activity of ASTX660 in Subjects with Advanced Solid Tumors and Lymphomas | |||||||||||||||||||||||||||||||||
| Medical condition: Advanced Solid Tumors and Lymphomas that are metastatic or unresectable: cohort 1:Recurrent/metastatic head and neck squamous cell carcinoma; cohort 2:Relapsed or refractory diffuse large B-cell ly... | |||||||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||
| Trial protocol: GB (Temporarily Halted) FR (Completed) HU (Completed) ES (Ongoing) BE (Completed) IT (Trial now transitioned) | |||||||||||||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||||||||||||
| EudraCT Number: 2009-017432-40 | Sponsor Protocol Number: MGN1703-C02 | Start Date*: 2010-04-13 | |||||||||||
| Sponsor Name:MOLOGEN AG | |||||||||||||
| Full Title: A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-Center Clinical Study to Evaluate Efficacy and Safety of a Maintenance Therapy with Immunomodulator MGN1703 in Patients with Advanced ... | |||||||||||||
| Medical condition: Patients with advanced colorectal carcinoma (AJCC Stage IV) with disease control after initial first-line therapy | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: DE (Completed) AT (Prematurely Ended) GB (Completed) CZ (Prematurely Ended) | |||||||||||||
| Trial results: View results | |||||||||||||
| EudraCT Number: 2022-000394-96 | Sponsor Protocol Number: NEOGAP-CRC-01 | Start Date*: 2023-01-31 | |||||||||||
| Sponsor Name:NEOGAP Therapeutics AB | |||||||||||||
| Full Title: A First-In-Human, Phase I/IIa Trial of the novel T cell Immunotherapy pTTL in Patients with Advanced Colorectal Cancer | |||||||||||||
| Medical condition: Stage IV colorectal cancer. | |||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
| Trial protocol: SE (Trial now transitioned) | |||||||||||||
| Trial results: (No results available) | |||||||||||||
| EudraCT Number: 2021-002181-41 | Sponsor Protocol Number: ACT16902 | Start Date*: 2021-12-08 | |||||||||||||||||||||||||||||||
| Sponsor Name:Sanofi-Aventis Recherche & Developpement | |||||||||||||||||||||||||||||||||
| Full Title: A Phase 2 non-randomized, open-label, multi-cohort, multi-center study assessing the clinical benefit of SAR444245 (THOR-707) combined with other anticancer therapies for the treatment of participa... | |||||||||||||||||||||||||||||||||
| Medical condition: Advanced and metastatic gastrointestinal cancer | |||||||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||
| Trial protocol: FR (Completed) DE (Completed) IT (Prematurely Ended) BE (Completed) ES (Prematurely Ended) NL (Completed) | |||||||||||||||||||||||||||||||||
| Trial results: View results | |||||||||||||||||||||||||||||||||
| EudraCT Number: 2020-000725-27 | Sponsor Protocol Number: 2020-000725-27 | Start Date*: 2020-05-28 | ||||||||||||||||||||||||||
| Sponsor Name:Center for Surgical Science, Department of Surgery, Zealand University Hospital | ||||||||||||||||||||||||||||
| Full Title: Intratumoral Influenza Vaccine for Early Colorectal Cancer | ||||||||||||||||||||||||||||
| Medical condition: Patients with colorectal cancer | ||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
| Trial protocol: DK (Prematurely Ended) | ||||||||||||||||||||||||||||
| Trial results: View results | ||||||||||||||||||||||||||||
| EudraCT Number: 2022-000339-21 | Sponsor Protocol Number: JK08.1.01 | Start Date*: 2022-08-29 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sponsor Name:Salubris Biotherapeutics, Inc. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Title: A Phase 1/2, Multicenter, Open Label, Dose Escalation & Dose Expansion Study of JK08, an IL-15 Antibody Fusion Protein Targeting CTLA-4, Monotherapy or in Combination in Patients with Unresectable ... | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Medical condition: Unresectable Locally Advanced or Metastatic Cancer | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Trial protocol: BE (Trial now transitioned) ES (Ongoing) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Trial results: (No results available) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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