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Clinical trials for Mechanical index

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44340   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    197 result(s) found for: Mechanical index. Displaying page 1 of 10.
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    EudraCT Number: 2020-000483-27 Sponsor Protocol Number: CCT38473 Start Date*: 2020-11-19
    Sponsor Name:St. Joseph’s Healthcare, McMaster University
    Full Title: Re-Evaluating the Inhibition of Stress Erosions: Gastrointestinal Bleeding Prophylaxis in ICU
    Medical condition: critical illness requiring mechanical ventilation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-001659-42 Sponsor Protocol Number: ANTITROMBINA Start Date*: 2020-04-18
    Sponsor Name:Fundación para la Investigación Biomédica de Córdoba
    Full Title: Pilot study of antithrombin as prophylaxis of acute respiratory distress syndrome in patients with COVID-19
    Medical condition: Confirmed SARS-CoV-2 respiratory infection with poor prognostic factors
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10051905 Coronavirus infection LLT
    20.1 10021881 - Infections and infestations 10061982 Severe acute respiratory syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015780-14 Sponsor Protocol Number: High-Dose-RemiSun Start Date*: 2009-12-28
    Sponsor Name:Abteilung für Anästhesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of high dose remifentanil on the reversal of established sunburn-induced hyperalgesia in human volunteers
    Medical condition: Volunteer study with 24 healthy volunteers to perform pain research and to study the reversal of hyperalgesia by IMP
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-003605-13 Sponsor Protocol Number: Remi-Capsaicin-2 Start Date*: 2008-12-03
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of remifentanil on the reversal of established capsaicin-induced hyperalgesia in human volunteers
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-004549-14 Sponsor Protocol Number: Remi-Capsaicin-1 Start Date*: 2008-02-15
    Sponsor Name:Department of Anaesthesie, General Intensive Care and Pain Therapy, Medical University of Vienna [...]
    1. Department of Anaesthesie, General Intensive Care and Pain Therapy, Medical University of Vienna
    2.
    Full Title: A novel role for remifentanil: the reversal of established capsaicin-induced hyperalgesia.
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-008475-34 Sponsor Protocol Number: Remi-Sunburn-1 Start Date*: 2009-02-25
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of remifentanil on the reversal of established sunburn-induced hyperalgesia in human volunteers.
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-011599-31 Sponsor Protocol Number: RemiAnes1 Start Date*: 2009-06-26
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of high-dose remifentanil on the reversal of established capsaicin-induced hyperalgesia in human volunteers
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP ist studied
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-001768-39 Sponsor Protocol Number: SURFABRON Start Date*: 2018-03-07
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
    Full Title: Randomized multicentre-controlled, placebo-controlled (1: 1) study to evaluate the efficacy and safety of Curosurf in patients under 12 months of age with moderate or severe acute respiratory distr...
    Medical condition: Acute severe hypoxic bronchiolitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10000686 Acute bronchiolitis LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-004426-93 Sponsor Protocol Number: lido_caps_sb_200509 Start Date*: 2005-10-28
    Sponsor Name:Department of Anaesthesia and General Intensive Care Medicine
    Full Title: Investigation of antihyperalgesic effect...
    Medical condition: volunteer study with healthy volunteers using the intradermal capsaicin injection and UV-B sunburn as models of hyperalgesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-004720-38 Sponsor Protocol Number: LATE-REC-SURF Start Date*: 2020-12-21
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Effects of late surfactant treatment delivered after a recruitment maneuver on respiratory outcomes in extremely low gestational age newborns: a randomized controlled trial – LATE-REC-SURF Trial.
    Medical condition: Preterm infants still requiring mechanical ventilation at 7-10 days of life.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004868 10076729 Very preterm infant LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-005627-32 Sponsor Protocol Number: IIVOP Start Date*: 2014-06-12
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: A randomised, double blind, placebo controlled crossover study of the influence of the HCN channel blocker ivabradine in a healthy volunteer pain model - an enriched population study
    Medical condition: Neuropathic Pain
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005601-37 Sponsor Protocol Number: RBHP2015PICKERING4 Start Date*: 2016-02-24
    Sponsor Name:CHU Clermont-Ferrand
    Full Title: IMPACT OF 5% LIDOCAINE MEDICATED PLASTER ON ALLODYNIC SYMPTOMS OF LOCALIZED NEUROPATHIC PAIN AFTER KNEE SURGERY. A prospective, randomized, placebo controlled study in parallel groups.
    Medical condition: Post operative neuropathic pain (PONP)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003670-40 Sponsor Protocol Number: PAN.1 Start Date*: 2018-04-05
    Sponsor Name:Beatrix Children's Hospital, University Medical Center Groningen
    Full Title: Pediatric Ards Neuromuscular blockade (PAN) study: Life-threatening acute respiratory failure in children: to breathe or not to breathe spontaneously, that's the question.
    Medical condition: Pediatric Acute Respiratory Distress Syndrome necessitating mechanical ventilation
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-002056-20 Sponsor Protocol Number: APHP200495 Start Date*: 2020-10-14
    Sponsor Name:Assistance Publique -Hôpitaux de Paris
    Full Title: FX06 to rescue acute respiratory distress syndrome during Covid-19 pneumonia : FX-COVID
    Medical condition: Patients admitted in participating ICUs who received mechanical ventilation for SARS-CoV-2 induced acute respiratory distress syndrome (ARDS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005832-34 Sponsor Protocol Number: NISTA-1 Start Date*: 2009-01-20
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: the role of antifungal prophylaxis with oral nystatin in critically ill patients
    Medical condition: critically ill patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000936-23 Sponsor Protocol Number: C20-15 Start Date*: 2020-03-09
    Sponsor Name:INSERM
    Full Title: Multi-centre, adaptive, randomized trial of the safety and efficacy of treatments of COVID-19 in hospitalized adults
    Medical condition: COVID-19 - Has laboratory-confirmed SARS-CoV-2 infection as determined by PCR, or other commercial or public health assay in any specimen < 72 hours prior to randomization. - Illness of any durat...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed) AT (Completed) PT (Completed) SK (Completed) CZ (Completed) NO (Prematurely Ended) IE (Prematurely Ended) HU (Completed) ES (Ongoing) GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004709-17 Sponsor Protocol Number: MP_SM01_2013 Start Date*: 2014-02-10
    Sponsor Name:Rigshospitalet
    Full Title: Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Inguinal Post-herniotomy Patients – A Randomized, Placebo-controlled, Double-blind Study
    Medical condition: First degree burn injury in healthy volunteers who 6-8 weeks prior have had done a Inguinal herniotomy .
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-001886-35 Sponsor Protocol Number: RHMCRI0399 Start Date*: 2020-05-15
    Sponsor Name:University Hospital Southampton NHS Foundation Trust
    Full Title: A clinical trial of nebulized surfactant for the Treatment of moderate to severe COVID-19 in adults
    Medical condition: COVID-19 infection in patients requiring endotrachael intubation
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10051905 Coronavirus infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-002994-39 Sponsor Protocol Number: Cx611-0204 Start Date*: 2016-04-06
    Sponsor Name:TIGENIX, S.A.U.
    Full Title: A phase Ib/IIa, randomised, double blind, parallel group, placebo controlled, multicentre study to assess the safety and efficacy of expanded Cx611 allogeneic adipose-derived stem cells (eASCs) for...
    Medical condition: Severe community-acquired bacterial pneumonia requiring mechanical ventilation and/or vasopressors.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) BE (Completed) LT (Completed) GB (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-004825-42 Sponsor Protocol Number: Notapplicablenow Start Date*: 2016-12-22
    Sponsor Name:ACTA
    Full Title: Effect of Delmopinol on treatment of Peri - implant mucositis : a randomised controlled clinical trial
    Medical condition: Peri implant mucositis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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