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Clinical trials for NPH insulin

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    73 result(s) found for: NPH insulin. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2012-001143-46 Sponsor Protocol Number: CLAF237ADE08 Start Date*: 2012-07-10
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A randomized open-label study to compare safety and efficacy of vildagliptin versus NPH insulin add-on to glimepiride in patients with type 2 diabetes mellitus that do not reach adequate glycemic c...
    Medical condition: type-2 diabetes mellitus that do not reach adequate glycemic control on their current sulfonylurea monotherapy
    Disease: Version SOC Term Classification Code Term Level
    15.0 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001642-14 Sponsor Protocol Number: n/a Start Date*: 2011-07-11
    Sponsor Name:University of Surrey
    Full Title: The effects of subcutaneous insulin detemir on glucose flux, pharmacokinetics and brain function in type one diabetes
    Medical condition: Type 1 diabetes mellitus
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003877-26 Sponsor Protocol Number: DP-01/05 Start Date*: 2006-05-23
    Sponsor Name:National Centre for Diabetes Care, 1st Dept. Medicine, Diabetes Unit
    Full Title: Comparison of the effect of insulin detemir and NPH insulin on dawn phenomenon in patients with Type 1 diabetes An open-labelled, randomised, cross-over, multi-center trial comparing the effect of...
    Medical condition: Type 1 diabetes mellitus, dawn phenomenon
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000959-15 Sponsor Protocol Number: HOE901/4057 Start Date*: 2005-05-17
    Sponsor Name:sanofi-aventis
    Full Title: A multicenter clinical trial to evaluate quality of life in patients with Type 2 diabetes before and after changing therapy to a combination of insulin glargine and oral antidiabetic drugs in a rea...
    Medical condition: Patients with Type 2 diabetes inadequately controlled on a combination of highest tolerable dose of oral antidiabetic drugs (OAD) + neutral protamine hagedorn (NPH) insulin for more than 3 months
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2007-003393-25 Sponsor Protocol Number: LANTU_L_02673 Start Date*: 2007-11-21
    Sponsor Name:sanofi-aventis, s.r.o.
    Full Title:
    Medical condition: Type 2 diabetes mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2007-005212-41 Sponsor Protocol Number: FSJD-HSJD-2 Start Date*: 2008-02-01
    Sponsor Name:HOSPITAL SANT JOAN DE DÉU
    Full Title: ESTUDIO COMPARATIVO DEL TRATAMIENTO CON BOMBA DE INSULINA SUBCUTANEA, INSULINA GLARGINA E INSULINA NPH EN NIÑOS DIABÉTICOS DE 0 A 6 AÑOS DE EDAD Comparative study between treatment with insulin pum...
    Medical condition: ESTUDIO COMPARATIVO DEL TRATAMIENTO CON BOMBA DE INSULINA SUBCUTANEA, INSULINA GLARGINA E INSULINA NPH EN NIÑOS DIABÉTICOS DE 0 A 6 AÑOS DE EDAD. Comparative study between treatment with insulin pu...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004640-35 Sponsor Protocol Number: EFC11681 Start Date*: 2015-03-17
    Sponsor Name:Sanofi
    Full Title: A 24-week, Randomized, Open-label, Parallel Group, Multicenter Comparison of Lantus® (Insulin Glargine) Given Once Daily Versus Neutral Protamine Hagedorn (NPH) Insulin in Children With Type 1 Diab...
    Medical condition: Type 1 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    17.1 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-001726-80 Sponsor Protocol Number: BAS 1 Start Date*: 2005-08-09
    Sponsor Name:Karolinska University Hospital, Stockholms Läns Landsting
    Full Title: Effects of new longacting insulin analogs on metabolic control, endogenous insulin production, GH/IGF-I axis and quality of life – comparison of NPH, glargine och detemir insulin from the debut of ...
    Medical condition: Type 1 Diabetes Mellitus (T1DM)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003941-13 Sponsor Protocol Number: I2R-MC-BIAK Start Date*: 2013-03-28
    Sponsor Name:Eli Lilly and Company
    Full Title: A Comparison of LY2605541 versus Human Insulin NPH as Basal Insulin Treatment in Insulin-Naïve Patients with Type 2 Diabetes Mellitus not Adequately Controlled with 2 or more Oral Antihyperglycemic...
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004861 10049746 Insulin-requiring type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) ES (Completed) DE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-010913-59 Sponsor Protocol Number: LANTU_L_04079 Start Date*: 2009-05-19
    Sponsor Name:Sanofi-Aventis Deutschland GmbH
    Full Title: Health Assessment, Patient treatment satisfaction and Quality-of-Life in insulin-naive type 2 diabetes Patients uncontrolled on OHA treatment initiating basal insulin therapy with either insulin gl...
    Medical condition: Diabetes mellitus type 2
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-003887-31 Sponsor Protocol Number: 2004/116 Start Date*: 2004-12-09
    Sponsor Name:Klinisk Farmakologisk Center og Med. Afd. M, Århus Sygehus, NBG
    Full Title: "Farmakodynamiske egenskaber af to langtidsvirkende insulinanaloger i sammenligning med NPH insulin"
    Medical condition: Healthy subjects.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000976-42 Sponsor Protocol Number: NN304-1659 Start Date*: 2005-07-21
    Sponsor Name:Novo Nordisk Pharma S.A.
    Full Title: A multi-centre, open-labelled, randomised, two-group parallel, treat-to-target trial comparing the weight change in overweight and obese subjects with type 2 diabetes after 26 weeks of treatment wi...
    Medical condition: Type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    7.0 10049746 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-000122-31 Sponsor Protocol Number: Lantu_L_00722 Start Date*: 2006-03-09
    Sponsor Name:Aventis Pharma s.r.o.
    Full Title: Srovnání fluktuací glykemií při bazální substituci humánním inzulínem NPH a inzulínovým analogem glargine (kontinuální měření glykemií)
    Medical condition: Type 1 and 2 diabetes mellitus
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2009-011231-12 Sponsor Protocol Number: EFC11202 Start Date*: 2009-11-11
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: A 24-week, randomized, open-label, parallel group multinational comparison of Lantus® (insulin glargine) given in the morning as once-a-day basal insulin versus Neutral Protamine Hagedorn (NPH) ins...
    Medical condition: Patients with type 1 diabetes mellitus, aged at least 1 year to less than 6 years
    Disease: Version SOC Term Classification Code Term Level
    12.0 10012609 LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) ES (Completed) DE (Completed) AT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-001461-18 Sponsor Protocol Number: NN304-1632 Start Date*: 2004-12-06
    Sponsor Name:NOVO NORDISK
    Full Title: A 20 week multi-national, open-labelled, randomised, three-group parallel trial comparing administration of insulin detemir morning, insulin detemir evening and NPH insulin evening as add-on to ora...
    Medical condition: Combined therapy in diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    6.1 10012601 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-000051-18 Sponsor Protocol Number: NN304-1689 Start Date*: 2006-12-18
    Sponsor Name:Novo Nordisk A/S
    Full Title: A 52-Week, Multinational, Multi-Centre, Open-Labelled, Randomised, Parallel, Efficacy and Safety Comparison of Insulin Detemir and NPH Insulin in Children and Adolescents 2-16 years with Type 1 Dia...
    Medical condition: Type I Diabetes
    Disease: Version SOC Term Classification Code Term Level
    8.1 10045228 Type I diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) FI (Completed) CZ (Completed) DK (Completed) BG (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2004-000616-70 Sponsor Protocol Number: HMR1964D/3001 Start Date*: 2004-12-17
    Sponsor Name:Aventis Pharmaceuticals, Inc.
    Full Title: Efficacy and safety of insulin glulisine compared with insulin lispro in children and adolescents with type 1 diabetes mellitus: a 26-week, multicenter, open, parallel clinical trial
    Medical condition: Type 1 diabetes mellitus
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed) NO (Completed) FI (Completed) SE (Completed) HU (Completed) GB (Completed) DE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-005500-33 Sponsor Protocol Number: NN304-4093 Start Date*: 2014-09-24
    Sponsor Name:Novo Nordisk A/S
    Full Title: A 26-week open label, randomised, 2-armed, parallel group, multi-centre trial investigating efficacy and safety of insulin detemir versus insulin Neutral Protamine Hagedorn in combination with the ...
    Medical condition: Diabetes Mellitus, Type 2
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) IT (Prematurely Ended) DE (Completed) HR (Prematurely Ended) GR (Prematurely Ended) ES (Prematurely Ended) PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003060-59 Sponsor Protocol Number: NN304-1761 Start Date*: 2007-03-16
    Sponsor Name:Novo Nordisk Limited
    Full Title: A 32 week, national, single-centre, open-labelled, randomised, cross-over trial comparing energy expenditure with insulin detemir versus NPH insulin using a basal-bolus regimen with insulin aspart ...
    Medical condition: Type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    8.1 10045228 Type I diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006589-41 Sponsor Protocol Number: NN304-1808 Start Date*: 2007-05-04
    Sponsor Name:Novo Nordisk Pharmaceutique S.A.S
    Full Title: Levemir® in ageing patients with type 2 diabetes A seven-month open-labelled randomised multi-centre two-group parallel trial comparing administration of insulin detemir once daily in the morning...
    Medical condition: Type 2 Diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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