- Trials with a EudraCT protocol (5)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
5 result(s) found for: NTRK gene fusions.
Displaying page 1 of 1.
EudraCT Number: 2017-004246-20 | Sponsor Protocol Number: 20810 | Start Date*: 2018-03-06 | ||||||||||||||||
Sponsor Name:Bayer Consumer Care AG | ||||||||||||||||||
Full Title: A Phase 1 Study of the TRK Inhibitor Selitrectinib (BAY 2731954) in Adult and Pediatric Subjects with Previously Treated NTRK Fusion Cancers Formerly: A Phase 1/2 Study of the TRK Inhibitor LOXO-1... | ||||||||||||||||||
Medical condition: NTRK fusion cancers previously treated with a TRK inhibitor | ||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: DK (Completed) FR (Completed) DE (Completed) ES (Completed) GB (GB - no longer in EU/EEA) IE (Completed) IT (Prematurely Ended) BE (Completed) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2015-003582-28 | Sponsor Protocol Number: LOXO-TRK-15002 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:Bayer Consumer Care AG | |||||||||||||
Full Title: A Phase 2 Basket Study of the Oral TRK Inhibitor larotrectinib in Subjects with NTRK Fusion-Positive Tumors | |||||||||||||
Medical condition: Solid Tumors | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) DK (Trial now transitioned) IE (Completed) ES (Trial now transitioned) PT (Trial now transitioned) FR (Trial now transitioned) DE (Trial now transitioned) SE (Trial now transitioned) BE (Completed) CZ (Completed) SK (Completed) NO (Completed) HU (Completed) PL (Completed) GR (Completed) IT (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-003498-16 | Sponsor Protocol Number: LOXO-TRK-15003 | Start Date*: 2017-02-10 | ||||||||||||||||||||||||||
Sponsor Name:Loxo Oncology Inc. | ||||||||||||||||||||||||||||
Full Title: A Phase 1/2 Study of the Oral TRK Inhibitor LOXO-101 in Pediatric Patients with Advanced Solid or Primary Central Nervous System Tumors | ||||||||||||||||||||||||||||
Medical condition: Central Nervous System Neoplasms and advanced solid tumors | ||||||||||||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: ES (Trial now transitioned) GB (GB - no longer in EU/EEA) DE (Trial now transitioned) SE (Trial now transitioned) DK (Trial now transitioned) FR (Trial now transitioned) NL (Trial now transitioned) IE (Trial now transitioned) PL (Completed) IT (Trial now transitioned) CZ (Trial now transitioned) | ||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-001155-39 | Sponsor Protocol Number: CO40778 | Start Date*: 2019-11-22 | ||||||||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd | ||||||||||||||||||
Full Title: A PHASE 1/2, OPEN-LABEL, DOSE-ESCALATION AND EXPANSION STUDY OF ENTRECTINIB (RXDX-101) IN PEDIATRICS WITH LOCALLY ADVANCED OR METASTATIC SOLID OR PRIMARY CNS TUMORS AND/OR WHO HAVE NO SATISFACTORY ... | ||||||||||||||||||
Medical condition: Solid tumors and primary central nervous system (CNS) tumors | ||||||||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) FR (Trial now transitioned) ES (Ongoing) DE (Trial now transitioned) IT (Trial now transitioned) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2020-002770-27 | Sponsor Protocol Number: DRA-104-001 | Start Date*: 2021-07-12 | |||||||||||
Sponsor Name:Dracen Pharmaceuticals, Inc. | |||||||||||||
Full Title: Phase 1 and phase 2a, first-in-human study of DRP-104, a glutamine antagonist, in adult patients with advanced solid tumors | |||||||||||||
Medical condition: Cancer, advanced solid tumors | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Ongoing) ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
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