- Trials with a EudraCT protocol (5)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
5 result(s) found for: NTRK gene fusions.
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EudraCT Number: 2017-004246-20 | Sponsor Protocol Number: 20810 | Start Date*: 2018-03-06 | ||||||||||||||||
Sponsor Name:Bayer Consumer Care AG | ||||||||||||||||||
Full Title: A Phase 1 Study of the TRK Inhibitor Selitrectinib (BAY 2731954) in Adult and Pediatric Subjects with Previously Treated NTRK Fusion Cancers Formerly: A Phase 1/2 Study of the TRK Inhibitor LOXO-1... | ||||||||||||||||||
Medical condition: NTRK fusion cancers previously treated with a TRK inhibitor | ||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: DK (Completed) FR (Ongoing) DE (Completed) ES (Ongoing) GB (GB - no longer in EU/EEA) IE (Completed) IT (Ongoing) BE (Completed) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-003582-28 | Sponsor Protocol Number: LOXO-TRK-15002 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:Bayer Consumer Care AG | |||||||||||||
Full Title: A Phase 2 Basket Study of the Oral TRK Inhibitor larotrectinib in Subjects with NTRK Fusion-Positive Tumors | |||||||||||||
Medical condition: Solid Tumors | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) DK (Ongoing) IE (Restarted) ES (Ongoing) PT (Ongoing) FR (Ongoing) DE (Ongoing) SE (Ongoing) BE (Ongoing) CZ (Ongoing) SK (Ongoing) NO (Completed) HU (Completed) PL (Ongoing) GR (Ongoing) IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-003498-16 | Sponsor Protocol Number: LOXO-TRK-15003 | Start Date*: 2017-02-10 | ||||||||||||||||||||||||||
Sponsor Name:Loxo Oncology Inc. | ||||||||||||||||||||||||||||
Full Title: A Phase 1/2 Study of the Oral TRK Inhibitor LOXO-101 in Pediatric Patients with Advanced Solid or Primary Central Nervous System Tumors | ||||||||||||||||||||||||||||
Medical condition: Central Nervous System Neoplasms and advanced solid tumors | ||||||||||||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: ES (Ongoing) GB (GB - no longer in EU/EEA) DE (Restarted) SE (Ongoing) DK (Ongoing) FR (Ongoing) NL (Ongoing) IE (Ongoing) PL (Ongoing) IT (Ongoing) CZ (Ongoing) | ||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-001155-39 | Sponsor Protocol Number: CO40778 | Start Date*: 2019-11-22 | ||||||||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd | ||||||||||||||||||
Full Title: A PHASE 1/2, OPEN-LABEL, DOSE-ESCALATION AND EXPANSION STUDY OF ENTRECTINIB (RXDX-101) IN PEDIATRICS WITH LOCALLY ADVANCED OR METASTATIC SOLID OR PRIMARY CNS TUMORS AND/OR WHO HAVE NO SATISFACTORY ... | ||||||||||||||||||
Medical condition: Solid tumors and primary central nervous system (CNS) tumors | ||||||||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) FR (Ongoing) ES (Ongoing) DE (Ongoing) IT (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2020-002770-27 | Sponsor Protocol Number: DRA-104-001 | Start Date*: 2021-07-12 | |||||||||||
Sponsor Name:Dracen Pharmaceuticals, Inc. | |||||||||||||
Full Title: Phase 1 and phase 2a, first-in-human study of DRP-104, a glutamine antagonist, in adult patients with advanced solid tumors | |||||||||||||
Medical condition: Cancer, advanced solid tumors | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Ongoing) ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
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