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Clinical trials for Osteosarcoma

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    70 result(s) found for: Osteosarcoma. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2006-005179-17 Sponsor Protocol Number: PPI/OS Start Date*: 2006-09-20
    Sponsor Name:ISTITUTI ORTOPEDICI RIZZOLI
    Full Title: Phase II clinical study on efficacy of proton pump inhibitors pre-treatment in osteosarcoma patients undergoing chemiotherapy
    Medical condition: Osteosarcoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031293 Osteosarcoma localised LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001659-36 Sponsor Protocol Number: 2011-001659-36 Start Date*: 2011-06-30
    Sponsor Name:ITALIAN SARCOMA GROUP
    Full Title: ABCB1/P-glycoprotein as biological marker for treatment of patient with high grade osteosarcoma
    Medical condition: Non metastatic osteosarcoma of the extremities
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031293 Osteosarcoma localised PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001010-42 Sponsor Protocol Number: 2012-001010-42 Start Date*: 2012-11-08
    Sponsor Name:ITALIAN SARCOMA GROUP
    Full Title: A multicenter, prospective, randomized clinical trial for patients with relapsed osteosarcoma
    Medical condition: High malignancy grade of osteosarcoma relapse
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031296 Osteosarcoma recurrent PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-002366-41 Sponsor Protocol Number: AIEOP-ISGOsM+ Start Date*: 2021-09-28
    Sponsor Name:ASSOCIAZIONE ITALIANA EMATOLOGIA ONCOLOGIA PEDIATRICA
    Full Title: Phase II, multicenter, randomized, open-label study with MAP +/- denosumab regimen for the treatment of patients with metastatic osteosarcoma
    Medical condition: Metastatic osteosarcoma
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031294 Osteosarcoma metastatic PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-001676-29 Sponsor Protocol Number: MK3475_PROMO Start Date*: 2016-10-27
    Sponsor Name:Oslo University Hospital (OUS)
    Full Title: PROMO: A phase II study of Pembrolizumab in patients with Relapsed Or Metastatic Osteosarcoma not eligible for curative surgery
    Medical condition: Osteosarcoma, not eligible for curative surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000615-84 Sponsor Protocol Number: OCTO_039 Start Date*: 2014-11-08
    Sponsor Name:University of Oxford
    Full Title: A Mechanistic Study Of Mifamurtide (MTP-PE) In Patients With Metastatic And/Or Recurrent Osteosarcoma
    Medical condition: Relapsed or metastatic osteosarcoma
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031291 Osteosarcoma PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed) NL (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004396-19 Sponsor Protocol Number: HGosteo-BAY Start Date*: 2007-12-24
    Sponsor Name:ITALIAN SARCOMA GROUP
    Full Title: Phase II, open label, non-randomized study of second or third line treatment with sorafenib (BAY 43-9006) in patients affected by relapsed high-grade osteosarcoma.
    Medical condition: patients affected by relapsed high-grade osteosarcoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031296 Osteosarcoma recurrent LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004762-28 Sponsor Protocol Number: OsteoREC2015 Start Date*: 2016-02-25
    Sponsor Name:ITALIAN SARCOMA GROUP
    Full Title: Multicentric prospective, randomized, clinical trial for the treatment of patient with relapsed Osteosarcoma (OS)
    Medical condition: high grade relapsed osteosarcoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031291 Osteosarcoma PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-005339-22 Sponsor Protocol Number: REGBONE Start Date*: Information not available in EudraCT
    Sponsor Name:Instytut Matki i Dziecka
    Full Title: To evaluate the efficacy and safety of regorafenib in patients with refractory primary bone tumors.
    Medical condition: Refractory primary bone tumors
    Disease: Version SOC Term Classification Code Term Level
    27.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10015562 Ewing's sarcoma metastatic PT
    27.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10015564 Ewing's sarcoma recurrent PT
    27.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031294 Osteosarcoma metastatic PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031296 Osteosarcoma recurrent PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-000912-97 Sponsor Protocol Number: H3E-EW-S115 Start Date*: 2007-07-26
    Sponsor Name:Eli Lilly and Company Limited
    Full Title: Phase II Trial of Pemetrexed in Second Line Advanced/Metastatic Osteosarcomas
    Medical condition: Advanced/Metastatic Osteosarcoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031294 Osteosarcoma metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) IT (Completed) ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-005341-38 Sponsor Protocol Number: P04720 Start Date*: 2008-06-09
    Sponsor Name:Schering Plough Research Institute
    Full Title: A Study to Determine the Activity of SCH 717454 in Subjects With Osteosarcoma or Ewing’s Sarcoma That Has Relapsed After Standard Systemic Therapy.
    Medical condition: Relapsed resectable and unresectable Osteosarcoma, Ewing Sarcoma.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) ES (Completed) SE (Prematurely Ended) NO (Prematurely Ended) NL (Completed) IT (Completed) CZ (Completed) PT (Prematurely Ended) HU (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-000561-12 Sponsor Protocol Number: S.E.R.I.O. Start Date*: 2011-06-07
    Sponsor Name:ITALIAN SARCOMA GROUP
    Full Title: A phase II, open label, non-randomized study of second or third line treatment with the combination of sorafenib and everolimus in patients affected by relapsed and non-resectable high-grade ost...
    Medical condition: Patients with high-grade Osteosarcoma, not resectable/metastatic, failing at least 2 different lines of standard tr4eatment for relapsed/metastatic disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031294 Osteosarcoma metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-001165-24 Sponsor Protocol Number: UC-0150/1704 Start Date*: 2018-06-12
    Sponsor Name:UNICANCER
    Full Title: A Multicentre, Randomised, Open-label, Phase 2 trial of mifamurtide combined with post-operative chemotherapy for newly diagnosed high risk osteosarcoma patients (metastatic osteosarcoma at diagnos...
    Medical condition: Patients ≤50 years old with high-risk osteosarcoma (defined as metastatic osteosarcoma at diagnosis or localised osteosarcoma with poor histological response) after pre-operative chemotherapy and s...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-002808-34 Sponsor Protocol Number: 001 Start Date*: 2007-02-09
    Sponsor Name:St. Antonius Hospital
    Full Title: A phase II study of isolated lung perfusion with melphalan followed by pulmonary metastatectomy in patients with resectable pulmonary metastases of colorectal carcinoma, soft tissue sarcoma and ost...
    Medical condition: resectable pulmonary metastases of colorectal carcinoma, soft tissue sarcoma and osteosarcoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001106-26 Sponsor Protocol Number: EC11-444-OSTEOSARC Start Date*: 2012-07-02
    Sponsor Name:JAVIER MARTÍN BROTO
    Full Title: PHASE II MULTICENTRIC AND PROSPECTIVE TRIAL WITH GEMCITABINE AND RAPAMYCIN IN SECOND LINE OF METASTATIC OSTEOSARCOMA
    Medical condition: Patients diagnosed with metastatic osteosarcoma cancer types that have been treated with chemotherapy and have active disease that permits to receive this treatment combination.
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003377-27 Sponsor Protocol Number: Sarcome 09/0603 Start Date*: 2007-02-20
    Sponsor Name:Fédération Nationale des Centres de Lutte Contre le Cancer
    Full Title: Etude Intergroupe (SFCE/GSF/GETO) OS2006 Zolédronate-Ostéosarcome Protocole de traitement des ostéosarcomes de l’enfant, de l’adolescent et de l’adulte comportant : - un essai randomisé - et des é...
    Medical condition: Les biphosphonates sont des analogues synthétiques des pyrophosphates endogènes dont la fonction principale est d’inhiber la résorption osseuse. Leur utilisation s’est imposée depuis une dizaine d’...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031291 Osteosarcoma LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-005554-62 Sponsor Protocol Number: ASSG03 Start Date*: 2012-04-16
    Sponsor Name:Australian Sarcoma Group (ASSG)
    Full Title: Pharmacokinetics and Pharmacodynamics of Doxorubicin in Children, Adolescents and young adults with Newly Diagnosed Osteosarcoma, Ewing Family of Tumours and Hodgkin Lymphoma A Multi-Institutional ...
    Medical condition: Ewing family of tumours Osteosarcoma Hodgkin lymphoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10020328 Hodgkin's lymphoma LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10015570 Ewing's tumour LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031291 Osteosarcoma LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003910-42 Sponsor Protocol Number: UC-0150/1309_SARCOME_12 Start Date*: 2014-05-06
    Sponsor Name:UNICANCER
    Full Title: A Randomized Phase II, placebo-controlled , multicenter study evaluating efficacy and safety of regorafenib in patients with metastatic bone sarcomas.
    Medical condition: Metastatic bone sarcomas: conventional high grade osteosarcoma, Ewing sarcoma of bone, intermediate or high-grade chondrosarcomas.
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10008736 Chondrosarcoma metastatic PT
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10015562 Ewing's sarcoma metastatic PT
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031294 Osteosarcoma metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-003595-12 Sponsor Protocol Number: ADVL1322-VEG116731 Start Date*: 2013-09-04
    Sponsor Name:GlaxoSmithKline
    Full Title: A Phase II Study of Pazopanib in Children, Adolescents and Young Adults with Refractory Solid Tumors.
    Medical condition: relapsed solid tumours in children, adolescents and young adults.
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA CZ (Completed) SK (Completed) ES (Completed) HU (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2004-000242-20 Sponsor Protocol Number: EURAMOS 1 Start Date*: 2005-04-05
    Sponsor Name:SSG
    Full Title: A randomised trial of the European and American Osteosarcoma Study group to optimize treatment strategies for resectable osteosarcoma based on histological response to pre-operative chemotherapy
    Medical condition: Ostesarcoma
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FI (Completed) NO (Completed) BE (Completed) IE (Completed) AT (Completed) CZ (Completed) GB (Completed)
    Trial results: View results
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