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Clinical trials for Penetrating trauma

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    15 result(s) found for: Penetrating trauma. Displaying page 1 of 1.
    EudraCT Number: 2018-000654-22 Sponsor Protocol Number: 6998 Start Date*: 2018-11-09
    Sponsor Name:Hôpitaux Universitaires de Strasbourg
    Full Title: A Prospective, Randomized Multicenter, Double Blind Clinical Trial Comparing Inhaled Dornase Alfa and Its Placebo to Reduce the Incidence of Moderate to Severe ARDS in Ventilated Trauma Patients in...
    Medical condition: Multiple Trauma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-002059-41 Sponsor Protocol Number: F7Trauma-1711 Start Date*: 2005-07-07
    Sponsor Name:Novo Nordisk A/S
    Full Title: A multi-center, randomized, double-blind, parallel group, placebo controlled trial to evaluate the efficacy and safety of activated recombinant factor VII (rFVIIa/NovoSeven®/NiaStase®) in severely ...
    Medical condition: Traumatic Hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    8.0 10053476 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) BE (Completed) GB (Completed) ES (Completed) CZ (Completed) IT (Completed) FI (Completed) SE (Completed) PT (Prematurely Ended) SI (Completed) GR (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2011-005235-22 Sponsor Protocol Number: ANZIC-RC/RB002 Start Date*: 2012-01-18
    Sponsor Name:Monash University
    Full Title: A randomised, placebo-controlled trial of erythropoietin in ICU patients with traumatic brain injury: Erythropoietin in Traumatic Brain Injury
    Medical condition: Traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10056380 Traumatic brain damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed) FR (Ongoing) DE (Ongoing) IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013115-35 Sponsor Protocol Number: MP4OX-09-TRA-204 Start Date*: 2009-11-05
    Sponsor Name:Sangart, Inc.
    Full Title: A multi-center, randomized, double-blind, controlled dose-finding study to evaluate the safety and efficacy of MP4OX treatment plus standard of care in severely injured trauma patients with lactic ...
    Medical condition: Trauma with lactic acidosis due to hemorrhagic shock
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023676 Lactic acidosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001409-40 Sponsor Protocol Number: S334.2.002 Start Date*: 2009-03-04
    Sponsor Name:Solvay Pharmaceuticals B.V.
    Full Title: A Randomized, Double blind, Placebo-Controlled Dose Escalation Study to Investigate the Safety and Pharmacokinetics after Single and Multiple Doses of SLV334 in Sequential Cohorts of Patients with ...
    Medical condition: Moderate and severe Traumatic Brain Injury (TBI)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060690 Traumatic brain injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) ES (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023129-39 Sponsor Protocol Number: MP4OX-10-TRA-205 Start Date*: 2011-03-22
    Sponsor Name:Sangart, Inc.
    Full Title: Estudio multicéntrico, aleatorizado, en doble ciego y controlado, para evaluar la seguridad y la eficacia del tratamiento con MP4OX, añadido al tratamiento habitual, en pacientes con traumatismo se...
    Medical condition: Pacientes con traumatismo severo y acidosis láctica por shock hemorrágico.//Severely injured trauma patients with lactic acidosis due to hemorrhagic shock.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10050841 Hemorrhagic shock LLT
    12.1 10023676 Lactic acidosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) AT (Completed) DE (Completed) GB (Completed) NO (Completed) IT (Ongoing) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002176-27 Sponsor Protocol Number: HC-G-H-1505 Start Date*: 2017-08-30
    Sponsor Name:Fresenius Kabi Deutschland GmbH
    Full Title: Pragmatic, prospective, randomized, controlled, double-blind, multicentre, multinational study on the safety and efficacy of a 6% Hydroxyethyl starch (HES) solution versus an electrolyte solution ...
    Medical condition: Hypovolaemia due to acute blood loss in trauma surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10021137 Hypovolaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) CZ (Completed) NL (Completed) ES (Restarted) FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2015-001401-13 Sponsor Protocol Number: RRK5174 Start Date*: 2016-04-07
    Sponsor Name:University Hospitals Birmingham NHS Foundation Trust
    Full Title: A Multi-Centre Randomised Controlled Trial of Pre-Hospital Blood Product Administration versus Standard Care for Traumatic Haemorrhage
    Medical condition: Hypotension after trauma, due to haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022117 - Injury, poisoning and procedural complications 10053476 Traumatic haemorrhage PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2021-000556-19 Sponsor Protocol Number: 6011 Start Date*: 2021-10-20
    Sponsor Name:Rigshospitalet, Department of Anaesthesia, Centre of Head and Orthopaedics
    Full Title: Comparing Restrictive vs. Liberal Oxygen Strategies for Trauma Patients: The TRAUMOX2 Trial
    Medical condition: Victims of trauma are often healthy individuals prior to the incident, but acquire numerous complications including sepsis and pulmonary complications and diminished quality of life after trauma. W...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10033316 Oxygen saturation PT
    20.0 100000004865 10050322 Oxygen supplementation LLT
    20.0 10022891 - Investigations 10033323 Oxygen tension LLT
    20.0 10022891 - Investigations 10033324 Oxygen tension abnormal NOS LLT
    20.0 10022891 - Investigations 10033325 Oxygen tension decreased LLT
    20.0 10022891 - Investigations 10033326 Oxygen tension increased LLT
    20.0 10022891 - Investigations 10033327 Oxygen tension normal LLT
    20.1 10022891 - Investigations 10068430 Arterial oxygen saturation LLT
    20.1 10022891 - Investigations 10068431 Arterial oxygen saturation increased LLT
    20.1 10022891 - Investigations 10068432 Arterial oxygen saturation decreased LLT
    20.1 10022891 - Investigations 10068433 Arterial oxygen saturation abnormal LLT
    20.1 10022891 - Investigations 10068434 Arterial oxygen partial pressure increased LLT
    20.1 10022891 - Investigations 10068435 Arterial oxygen partial pressure decreased LLT
    20.1 10022891 - Investigations 10068436 Arterial oxygen partial pressure abnormal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000756-34 Sponsor Protocol Number: 2012.001 Start Date*: 2012-11-02
    Sponsor Name:NeuroVive Pharmaceutical AB
    Full Title: Copenhagen Head Injury Ciclosporin (CHIC) Study: An open-label, uncontrolled Phase II -study to investigate pharmacokinetics, safety and biomarkers of effectiveness of NeuroSTAT® (ciclosporin) i...
    Medical condition: Severe Traumatic Brain Injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004480-12 Sponsor Protocol Number: 2017-991 Start Date*: 2018-01-16
    Sponsor Name:Rigshospitalet
    Full Title: Restrictive vs. Liberal Oxygen Therapy for Trauma patients. PILOT: The TRAUMOX Trial
    Medical condition: Victims of trauma are often healthy individuals prior to the incident, but acquire numerous complications including sepsis and pulmonary complications as well as long-term complications and dimini...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10050322 Oxygen supplementation LLT
    20.0 100000004848 10033321 Oxygen saturation low LLT
    20.0 100000004848 10033323 Oxygen tension LLT
    20.0 100000004848 10033324 Oxygen tension abnormal NOS LLT
    20.0 100000004848 10033325 Oxygen tension decreased LLT
    20.0 100000004848 10033326 Oxygen tension increased LLT
    20.0 100000004848 10033327 Oxygen tension normal LLT
    20.0 100000004848 10033319 Oxygen saturation high LLT
    20.0 100000004848 10059945 Partial arterial pressure of oxygen LLT
    20.1 100000004848 10068430 Arterial oxygen saturation LLT
    20.1 100000004848 10068431 Arterial oxygen saturation increased LLT
    20.1 100000004848 10068432 Arterial oxygen saturation decreased LLT
    20.1 100000004848 10068433 Arterial oxygen saturation abnormal LLT
    20.1 100000004848 10068434 Arterial oxygen partial pressure increased LLT
    20.1 100000004848 10068435 Arterial oxygen partial pressure decreased LLT
    20.1 100000004848 10068436 Arterial oxygen partial pressure abnormal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-022168-11 Sponsor Protocol Number: TR-701-112 Start Date*: 2011-03-08
    Sponsor Name:Trius Therapeutics, Inc.
    Full Title: A Phase 3 Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of 6-Day Oral TR-701 Free Acid and 10-Day Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin...
    Medical condition: Acute Bacterial Skin and Skin Structure Infections
    Disease: Version SOC Term Classification Code Term Level
    13.1 10021881 - Infections and infestations 10040872 Skin infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) LV (Completed) HU (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2017-001605-32 Sponsor Protocol Number: BPR-CS-008 Start Date*: 2017-10-06
    Sponsor Name:Basilea Pharmaceutica International Ltd
    Full Title: A randomized, double-blind, multicenter study to establish the safety and efficacy of ceftobiprole medocaril compared with vancomycin plus aztreonam in the treatment of acute bacterial skin and ski...
    Medical condition: Acute bacterial skin and skin structure infections
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10052891 Skin bacterial infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2011-002860-26 Sponsor Protocol Number: TR701-113 Start Date*: 2011-12-21
    Sponsor Name:Trius Therapeutics, Inc.
    Full Title: A Phase 3 Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous to Oral 6-Day TR-701 Free Acid and Intravenous to Oral 10-Day Linezolid for the Treatment of...
    Medical condition: Acute Bacterial Skin and Skin Structure Infections
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10040872 Skin infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-002309-30 Sponsor Protocol Number: P04230 Start Date*: 2007-06-18
    Sponsor Name:Schering-Plough Research Institute, a division of Schering Corporation
    Full Title: A Randomized Placebo-Controlled Efficacy and Safety Study of 1-Year Duration with High and Medium Dose Inhaled Mometasone Furoate/Formoterol Combination Formulation Compared With Formoterol and Hig...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10009033 Chronic obstructive pulmonary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) NL (Completed) HU (Completed) SK (Completed) EE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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