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Clinical trials for Preoperative care

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    143 result(s) found for: Preoperative care. Displaying page 1 of 8.
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    EudraCT Number: 2016-004555-79 Sponsor Protocol Number: 16-115 Start Date*: 2017-08-08
    Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty
    Full Title: Impact of preoperative midazolam on outcome of elderly patients: a multicenter randomised controlled trial
    Medical condition: Under investigation are elderly patients (≥65 years of age) undergoing each kind of surgery with planned general or combined regional and general anaesthesia. Primary, we will investigate the posto...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000980-42 Sponsor Protocol Number: V1.1/13.05.2014 Start Date*: 2014-09-26
    Sponsor Name:Medical University Vienna
    Full Title: Feasibility and safety of intensified preoperative glucose control in patients with type 2 diabetes undergoing cardiovascular surgery – a pilot study
    Medical condition: The objective of this study is to investigate whether a targeted preoperative glucose control before planned cardiac surgery by i.v. insulin infusion (intensified glycemic control, ICG) versus st...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004671-39 Sponsor Protocol Number: 2019/318 Start Date*: 2020-01-28
    Sponsor Name:Universitair Ziekenhuis Brussel (UZ Brussel)
    Full Title: The effect of handheld-multimedia versus midazolam premedication on the level of perioperative anxiety in pediatric day-care. A randomized controlled trial.
    Medical condition: Perioperative anxiety in children scheduled for an elective circumcision, dental care or tonsillectomy/adenoidectomy in day-care
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-003184-65 Sponsor Protocol Number: TPL107 Start Date*: 2020-02-24
    Sponsor Name:Vifor Pharma
    Full Title: POREIIL - Postoperative replacement of intraoperative iron losses
    Medical condition: perioperative bleeding induced iron losses and anemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002890-31 Sponsor Protocol Number: Pregab1 Start Date*: 2006-08-25
    Sponsor Name:Dept. of Anaesthesia, Medical University of Vienna
    Full Title: Does Pregabalin reduce preoperative anxiety: a placebo controlled study
    Medical condition: Patients should receive Pregabalin or placebo as premedication one hour before ambulatory elective surgery. After this they have to assess their anxiety and pain with Visual Analog Scale (VAS) for ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004239-63 Sponsor Protocol Number: NL68231.078.18 Start Date*: 2019-08-23
    Sponsor Name:Erasmus MC
    Full Title: Botulinum toxin (BOTOX®) to prevent post-operative pancreatic fistula in patients who undergo distal pancreatectomy. PROFIT study.
    Medical condition: Post-operative pancreatic fistula
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10049192 Pancreatic fistula PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005445-16 Sponsor Protocol Number: NL74623.078.20 Start Date*: 2021-02-23
    Sponsor Name:Erasmus MC, University Medical Center Rotterdam
    Full Title: Fasting before live kidney donation, effect on donor wellbeing and postoperative recovery
    Medical condition: Preoperative fasting in combination with a low-dose laxative and postoperative recovery and complications in living kidney donors
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013707-63 Sponsor Protocol Number: 1 Start Date*: 2010-03-05
    Sponsor Name:C.U.B ERASME HOSPITAL
    Full Title: POSTOPERATIVE ANALGESIA USING PREPERITONEAL CONTINUOUS INFUSIONS OF ROPIVACAINE IN PATIENTS UNDERGOING LIVER SURGERY -CONSEQUENCES ON ROPIVACAINE METABOLISM
    Medical condition: PATIENTS WITH HEPATIC TUMORS BUT WITH A GOOD HEPATIC FUNCTION BEFORE SURGERY
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004111-42 Sponsor Protocol Number: TRAP Start Date*: 2014-03-11
    Sponsor Name:Academic Medical Center
    Full Title: Feasibility study of chemoradiation, TRAstuzumab and Pertuzumab in resectable HER2+ esophageal carcinoma
    Medical condition: Esophageal carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-006750-26 Sponsor Protocol Number: ABCSG R04 / TAKO 08 Start Date*: 2008-01-21
    Sponsor Name:Austrian Breast & Colorectal Cancer Study Group (ABCSG)
    Full Title: Preoperative combined RadioChemo-MolecularTargetedTherapie (RC-MTTx) of the locally advanced rectal carcinoma (cT3NxM0) – a phase II pilot study with preoperative application of capecitabine (Xelod...
    Medical condition: locally advanced rectal carcinoma (cT3NxM0)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024354-11 Sponsor Protocol Number: ABCSGR05 Start Date*: 2011-03-03
    Sponsor Name:ABCSG (Austrian Breast & Colorectal Cancer Study Group)
    Full Title: Preoperative induction chemotherapy in combination with Bevacizumab followed by combined chemoradiotherapy in locally advanced rectal cancer with high risk of recurrence- phase II pilot study with ...
    Medical condition: locally advanced rectal cancer with high risk of recurrence
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-004890-21 Sponsor Protocol Number: NL72427.068.19 Start Date*: 2021-01-18
    Sponsor Name:Academic Hospital Maastricht (azM)
    Full Title: Effectiveness of Periocular drug Injection in CATaract surgery
    Medical condition: cystoid macular edema (CME)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) DE (Prematurely Ended) AT (Prematurely Ended) PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-001874-12 Sponsor Protocol Number: C-12-071 Start Date*: 2013-11-07
    Sponsor Name:Alcon Research, Ltd
    Full Title: Randomized, Double-Masked, Vehicle Controlled, Clinical Evaluation To Assess The Safety And Efficacy Of Nepafenac Ophthalmic Suspension, 0.3% For Improvement In Clinical Outcomes Among Diabetic Sub...
    Medical condition: Cataract surgery in diabetic patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) IT (Completed) DE (Completed) AT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-022416-40 Sponsor Protocol Number: 3591 Start Date*: 2011-09-30
    Sponsor Name:The Royal Marsden NHS Foundation Trust
    Full Title: A Translational, proof of the concept, study Of Pre-operative Pazopanib in treatment-naive patients with resectable soft tissue Sarcomas (TOPPS)
    Medical condition: Resectable Soft Tisue Sarcomas (cancer of conective soft tissues)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-000714-74 Sponsor Protocol Number: 1.0 Start Date*: 2008-07-15
    Sponsor Name:Institution of Paediatric Anaesthesia and intensiv care, Astrid Lindgren Childrens Hospital, Karolin
    Full Title: Premedication in paediatric patients: Dose finding study of clonidine administrated as nasal aerosol.
    Medical condition: Premedication prior to anaesthesia
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001011-36 Sponsor Protocol Number: ICO-A-2016-04 Start Date*: 2017-05-24
    Sponsor Name:INSTITUT DE CANCEROLOGIE DE L'OUEST
    Full Title: Multicentric, comparative, randomized, open study comparing an early post-operative prophylactic non-invasive ventilation (NIV) to standard post-operative care in patients at high-risk of respir...
    Medical condition: Legally adult patient going to have an operation under loco-regional or general anesthesia.
    Disease: Version SOC Term Classification Code Term Level
    19.1 10022117 - Injury, poisoning and procedural complications 10072651 Postoperative respiratory failure PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2014-003167-38 Sponsor Protocol Number: NL50643.09r.r4 Start Date*: 2015-04-28
    Sponsor Name:Radboudumc
    Full Title: 68Ga-NODAGA-exendin-4 PET/CT in patients with AHH - a prospective comparative evaluation of preoperative imaging Under the FP7 project Betacure (602812); Personalized diagnosis and treatment of hy...
    Medical condition: Adult endogenous hyperinsulinemic hypoglycemia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000333-40 Sponsor Protocol Number: 11-534 Start Date*: 2012-07-30
    Sponsor Name:University Medical Center Utrecht
    Full Title: Towards plannable breast surgery: diagnostic accuracy of microbubble enhanced Iodine-125 seed localization of the sentinel lymph node (MIB study)
    Medical condition: Patient with breast cancer with an indication for sentinel lymph node biopsy
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-003740-62 Sponsor Protocol Number: ABCSG R03 (96) /TAKO 06 Start Date*: 2005-10-27
    Sponsor Name:ABCSG (Austrian Breast & Colorectal Cancer Study Group)
    Full Title: Preoperative chemoradiation with capecitabine and cetuximab within a multidisciplinary therapeutic approach in patients with operable T3-T4 rectal cancer: a phase II study
    Medical condition: locally advanced operable rectal carcinoma (cT3-T4NxM0)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-000017-21 Sponsor Protocol Number: SATA1 Start Date*: 2013-10-11
    Sponsor Name:Aarhus University Hospital, Dept. of anaesthesiology and intensive care
    Full Title: SATA 1 – Stress, Anxiety and Type A personality and analgetics (qualityinsurance project). Level of analgetics in anaesthesia for cardiac surgery evaluated by BIS and EEG monitoring, haemodynamic ...
    Medical condition: Anaesthesia and recovery in cardiac surgery patients.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10021722 Induction and maintenance anaesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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