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Clinical trials for Sprains

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    24 result(s) found for: Sprains. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2004-000843-61 Sponsor Protocol Number: 7148LBMC02 Start Date*: 2004-08-12
    Sponsor Name:ZAMBON GROUP
    Full Title: Efficacy and tolerability of topical Ketoprofen TDS patch KEOFIX in the treatment of traumatic painful soft-tissue injuries
    Medical condition: ANKLE SPRAIN
    Disease: Version SOC Term Classification Code Term Level
    6.1 10023229 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-001038-32 Sponsor Protocol Number: 48-03LXPU Start Date*: 2019-10-15
    Sponsor Name:Lead Chemical Company Ltd
    Full Title: Randomized, controlled, double-blind, multi-center trial to evaluate the efficacy and safety of a Loxoprofen sodium 60 mg tape medicated plaster vs. placebo in the local symptomatic and short-term ...
    Medical condition: Acute blunt, soft tissue injuries of the limbs
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10041775 Sprains and strains of ankle and foot LLT
    20.0 100000004863 10032894 Other specified sites of sprains and strains LLT
    20.0 100000004863 10041777 Sprains and strains of elbow and forearm LLT
    20.0 100000004863 10041790 Sprains and strains of shoulder and upper arm LLT
    20.0 100000004863 10041798 Sprains and strains of wrist and hand LLT
    21.0 100000004866 10019428 Hematoma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000383-88 Sponsor Protocol Number: CSC/Keto-01/06 Start Date*: 2006-06-19
    Sponsor Name:CSC Pharmaceuticals Handels GmbH
    Full Title: A Multicenter, Parallel-group, Double-blind, Placebo Controlled and Randomized Clinical Study to Assess the Efficacy and Safety of Ketoprofen 10% Cutaneous Spray versus Placebo in Patients with Acu...
    Medical condition: Painful, acute ankle sprains, as a model of general traumatic soft-tissue injuries
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002549 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) SK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003773-28 Sponsor Protocol Number: 06EU/FHp03 Start Date*: 2007-01-11
    Sponsor Name:IBSA
    Full Title: A multicentre, prospective, double-blind, in parallel groups randomised, versus placebo and versus reference product controlled, confirmatory clinical trial of the efficacy and tolerance of Flector...
    Medical condition: ankle sprains
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023229 Joint sprain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-005240-33 Sponsor Protocol Number: MENTH001 Start Date*: 2016-02-26
    Sponsor Name:The Mentholatum Company Ltd
    Full Title: A single centre, randomised, single-blind, parallel group single dose study to compare the speed of onset of ibuprofen gel, ibuprofen gel with levomenthol, and diclofenac gel in the relief of pain ...
    Medical condition: Pain of strains, sprains and sports injuries
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022117 - Injury, poisoning and procedural complications 10065016 Post-traumatic pain PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-003778-30 Sponsor Protocol Number: DRO-200/III/21/1 Start Date*: 2021-12-29
    Sponsor Name:Drossapharm AG
    Full Title: Randomized, controlled, multi-center trial to evaluate the efficacy and safety of Lixim 70 mg wirkstoffhaltiges Pflaster (etofenamate 70 mg medicated plaster) vs. placebo in the local symptomatic a...
    Medical condition: Acute strains, sprains or bruises of soft tissues following blunt trauma, e.g. sports injuries
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-005165-14 Sponsor Protocol Number: TK-254R-0201 Start Date*: 2021-03-25
    Sponsor Name:Teikoku Seiyaku Co Ltd.
    Full Title: Randomized, controlled, double-blind, multi-center trial to evaluate the
    Medical condition: Acute strains, sprains or bruises of the extremities following blunt trauma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10002549 Ankle sprain LLT
    20.0 100000004863 10002550 Ankle sprains and strains LLT
    20.0 100000004863 10028338 Muscle sprains LLT
    20.0 100000004859 10028361 Muscular pain LLT
    21.1 100000004859 10028362 Muscular pains LLT
    20.1 100000004863 10006502 Bruise LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-005217-41 Sponsor Protocol Number: 51-03FPAEU Start Date*: 2021-09-06
    Sponsor Name:Lead Chemical Company Ltd
    Full Title: Randomized, controlled, multi-center trial to evaluate the efficacy and safety of a Flurbiprofen 40 mg cutaneous hydrogel medicated plaster vs. placebo and vs. a marketed active comparator in the l...
    Medical condition: pain in acute strains, sprains or bruises of the soft tissues following blunt trauma, e.g. sports injuries
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000909-22 Sponsor Protocol Number: MDS-KET-2004-01 Start Date*: 2004-08-27
    Sponsor Name:MDS Pharma Services
    Full Title: Comparative efficacy and tolerability of a topical ketoprofen TDS patch vs ketoprofen gel in the treatment of acute pain in soft-tissue injuries
    Medical condition: Acute pain in soft-tissue injuries of lower limbs, except toes
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003875-22 Sponsor Protocol Number: CHUB-Diprophos-IPP Start Date*: 2016-12-08
    Sponsor Name:Centre Hospitalier Universitaire Brugmann
    Full Title: Randomized controlled prospective study on the injection of corticoids for the treatment of acute sprains of the proximal interphalangeal joints of the fingers (thumb excluded).
    Medical condition: Acute sprain of the proximal interphalangeal joints of the fingers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-006465-38 Sponsor Protocol Number: 21EU-Fpf02 Start Date*: 2022-06-06
    Sponsor Name:IBSA Institut Biochimique S.A.
    Full Title: A Randomized, Double-Blind, Multi-Centre, Placebo-Controlled, Active Comparator Study to Evaluate the Efficacy and Safety of a diclofenac epolamine (DHEP) 2.6% medicated plaster in the treatment of...
    Medical condition: Acute pain in mild/moderate ankle sprains
    Disease: Version SOC Term Classification Code Term Level
    21.1 10022117 - Injury, poisoning and procedural complications 10024453 Ligament sprain PT
    23.1 10022117 - Injury, poisoning and procedural complications 10022117 Injury, poisoning and procedural complications SOC
    20.0 10022117 - Injury, poisoning and procedural complications 10028288 Muscle, tendon and ligament injuries HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004343-92 Sponsor Protocol Number: 21559 Start Date*: 2021-06-23
    Sponsor Name:Bayer Healthcare LLC.
    Full Title: Randomized, Controlled, Double-blind, Placebo-controlled, Multi-center Hypothesis-finding Trial to Compare the Efficacy and Safety of a 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel and ...
    Medical condition: acute strains, sprains or bruises of the lower extremities following blunt trauma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-003543-29 Sponsor Protocol Number: 48-04LXPU Start Date*: 2021-05-07
    Sponsor Name:Lead Chemical Company Ltd.
    Full Title: Randomized, controlled, multi-center trial to evaluate the efficacy and safety of a Loxoprofen sodium 60 mg medicated plaster vs. placebo and vs. a marketed comparator in the local symptomatic and ...
    Medical condition: Acute blunt, soft tissue injuries of the muscles or limbs
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-000725-69 Sponsor Protocol Number: Z7202L03 Start Date*: 2011-06-30
    Sponsor Name:Zambon S.p.A.
    Full Title: Efficacy, tolerability and safety of Z7202, a once daily diclofenac diethylamine medicated plaster in the local treatment of painful conditions. Multi-centre, multinational, placebo- controlled, do...
    Medical condition: Localised painful conditions
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10068757 Musculoskeletal and connective tissue pain and discomfort HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) LT (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2010-022736-37 Sponsor Protocol Number: Z7202L02 Start Date*: 2011-02-09
    Sponsor Name:Zambon S.p.A.
    Full Title: Efficacy, tolerability and safety of Z7202, a once daily Diclofenac Diethylamine (DEA) medicated plaster in comparison with Flector®, a twice daily Diclofenac Hydroxyethylpyrrolidine medicated plas...
    Medical condition: Diagnosis of single localized post-traumatic painful condition
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10065016 Post-traumatic pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2010-024641-71 Sponsor Protocol Number: 071(D)SC10102 Start Date*: 2011-05-12
    Sponsor Name:ANGELINI
    Full Title: A randomized, multicenter, double-blind study assessing the efficacy and safety of two topical 10% naproxen gel formulations in the treatment of benign soft-tissue injuries.
    Medical condition: Benign soft-tissue injuries.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10028391 Musculoskeletal pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-011571-71 Sponsor Protocol Number: VOPO-P-307 Start Date*: 2009-07-20
    Sponsor Name:Novartis Consumer Health SA
    Full Title: A randomized, double-blind, multi-center, placebo-controlled, 3-treatment arm, parallel group study to evaluate the efficacy and safety of diclofenac diethylamine 2.32% gel applied twice or three t...
    Medical condition: ankle sprain Grade I or II
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020935-38 Sponsor Protocol Number: VOSG-P-318 Start Date*: 2010-12-14
    Sponsor Name:Novartis Consumer Health
    Full Title: A randomized, double-blind, multi-center, placebo-controlled, parallel group study to evaluate the efficacy and safety of diclofenac sodium topical gel 1% applied four times daily in subjects with ...
    Medical condition: Ankle sprain, Grade I-II
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002549 Ankle sprain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020489-82 Sponsor Protocol Number: Q16-10-01 Start Date*: 2010-08-25
    Sponsor Name:Fidia Farmaceutici S.p.A.
    Full Title: Randomised, double-blind, placebo-controlled, parallel-groups, multi-centre clinical trial Phase III with Diclofenac Sodium 140 mg medicated plaster in patients with fresh impact injuries of the li...
    Medical condition: Fresh impact injuries of the limbs (Contusions, strains and sprains)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001032-99 Sponsor Protocol Number: DRO-200-III-20-1 Start Date*: 2020-09-03
    Sponsor Name:Drossapharm AG
    Full Title: Randomized, controlled, double-blind, multi-center trial to evaluate the efficacy and safety of “Lixim 70 mg wirkstoffhaltiges Pflaster” (etofenamate 70 mg medicated plaster) applied once daily (ev...
    Medical condition: Acute ankle sprain, Grade I
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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