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Clinical trials for Toxicology

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    47 result(s) found for: Toxicology. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2016-001511-20 Sponsor Protocol Number: 1 Start Date*: 2017-01-19
    Sponsor Name:Institute for Pharmacology and Toxicology
    Full Title: Pharmacokinetica of Cefuroxime
    Medical condition: hip or knee replacement or spine bone surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005985-30 Sponsor Protocol Number: rosucaf2 Start Date*: 2009-01-22
    Sponsor Name:Department of Pharmacology-Toxicology
    Full Title: Is augmentation of PORH by rosuvastatin adenosine-receptor mediated?
    Medical condition: mechanism of influence of statins on human adaptive mechanisms in hypoxic circumstances
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021143 Hypoxia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003854-80 Sponsor Protocol Number: 02B2005 Start Date*: 2006-01-31
    Sponsor Name:Department of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-University
    Full Title: Modulation of the Surgical Inflammatory Response by Etoricoxib: Peripheral versus Central
    Medical condition: Patients with osteoarthritis undergoing elective primary single hip arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-004445-42 Sponsor Protocol Number: 1 Start Date*: 2007-05-22
    Sponsor Name:Institut for Pharmacology and Toxicology
    Full Title: Pharmacokinetics of Cetriaxon in bone
    Medical condition: hip replacement
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003898-42 Sponsor Protocol Number: 2 Start Date*: 2008-03-19
    Sponsor Name:Institut for Pharmacology and Toxicology
    Full Title: Pharmacokinetica of levofloxacine in bone
    Medical condition: hip or knee replacement
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003035-35 Sponsor Protocol Number: HS-14-499 Start Date*: 2015-11-09
    Sponsor Name:Braeburn Pharmaceuticals
    Full Title: An Open-Label Multicenter Study Assessing the Long-Term Safety of a Once-Weekly and Once-Monthly, Long-Acting Subcutaneous Injection Depot of Buprenorphine (CAM2038) in Adult Outpatients with Opioi...
    Medical condition: Opioid Use Disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) DK (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2016-004710-95 Sponsor Protocol Number: REPAS161118 Start Date*: 2018-02-07
    Sponsor Name:Beroendecentrum Stockholm
    Full Title: Extended-release injectable suspension naltrexone (XR-NTX) as an adjunt pharmacotherapy for prevention of substance use in patients with SUD who are currently in treatment for ADHD: A multicenter r...
    Medical condition: Amphetamine dependence and ADHD (Attention-Deficit/Hyperactivity Disorder)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004762-40 Sponsor Protocol Number: Rosudip01 Start Date*: 2007-10-18
    Sponsor Name:Dept. Pharmacology and Toxicology
    Full Title: Rosuvastatin augments dipyridamole induced vasodilation by increased adenosine receptor stimulation
    Medical condition: Ischemia-reperfusion injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023034 Ischemia peripheral LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004620-20 Sponsor Protocol Number: P3 Start Date*: 2008-05-21
    Sponsor Name:department of Pharmacology-Toxicology RUNMC
    Full Title: Persantin Preceding PCI
    Medical condition: myocardial damage due to PCI
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065554 Myocardial infarction prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-000189-12 Sponsor Protocol Number: ABR43234 Start Date*: 2013-03-14
    Sponsor Name:University Medical Centre Nijmegen
    Full Title: Effects of the selective mineralocorticoid receptor antagonist eplerenone on extracellular formation of adenosine
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000709-26 Sponsor Protocol Number: 50510617 Start Date*: 2022-01-18
    Sponsor Name:Rigshospitalet, Centre of Head and Orthopaedics
    Full Title: Drug test detection 24 hours after nasal administration of cocaine as a local vasoconstrictor prior to nasal intubation
    Medical condition: Residual systemic cocaine after administration as local nasal vasoconstrictor
    Disease: Version SOC Term Classification Code Term Level
    22.0 100000004867 10013685 Drug effect prolonged LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-000691-11 Sponsor Protocol Number: 89303200 Start Date*: 2022-01-18
    Sponsor Name:Rigshospitalet
    Full Title: Comparison of the effect of xylometazoline and cocaine on epistaxis when administered as local vasoconstrictors prior to nasal intubation
    Medical condition: Epistaxis upon nasal intubation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-001817-35 Sponsor Protocol Number: 111958 Start Date*: 2021-08-04
    Sponsor Name:Radboud University Medical Center
    Full Title: Suboxone (buprenorphine/naloxone) versus methadone opioid rotation in patients with escalated opioid use and chronic pain: a randomized trial.
    Medical condition: Opioid use disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-006170-28 Sponsor Protocol Number: E2007-G000-307 Start Date*: 2008-09-15
    Sponsor Name:Eisai Ltd
    Full Title: An Open-Label Extension Phase of the Double-Blind, Placebo-Controlled, Dose-scalation, Parallel-Group Studies to Evaluate the Efficacy and Safety of E2007 (perampanel) Given as Adjunctive Therapy i...
    Medical condition: Epilepsy: refractory partial seizures with or without secondary generalisation
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) ES (Completed) AT (Completed) BE (Completed) PT (Completed) LT (Completed) NL (Completed) HU (Completed) FR (Completed) GB (Completed) SE (Completed) EE (Completed) LV (Completed) DK (Completed) IT (Completed) DE (Completed) FI (Completed) BG (Prematurely Ended) GR (Completed)
    Trial results: View results
    EudraCT Number: 2014-002630-31 Sponsor Protocol Number: CSOM230C2413 Start Date*: 2015-03-25
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A phase IIIb multicenter, open-label, single arm study to evaluate the efficacy and safety of pasireotide in patients with acromegaly inadequately controlled with first generation somatostatin ana...
    Medical condition: Acromegaly
    Disease: Version SOC Term Classification Code Term Level
    19.0 10014698 - Endocrine disorders 10000599 Acromegaly PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) BE (Completed) PT (Completed) IT (Completed) FR (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2011-005343-27 Sponsor Protocol Number: Metformin-FMD001 Start Date*: 2012-01-27
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Can metformin prevent endothelial ischemia and reperfusion injury? The Metformin-FMD trial.
    Medical condition: ischemia and reperfusion injury endothelial dysfunction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10063837 Reperfusion injury PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000322-21 Sponsor Protocol Number: TIP5 Start Date*: 2012-05-29
    Sponsor Name:Sanaria Inc.
    Full Title: Controlled human malaria infection after immunization with cryopreserved Plasmodium falciparum sporozoites under chloroquine prophylaxis
    Medical condition: Controlled human malaria infection after immunization with cryopreserved Plasmodium falciparum sporozoites under chloroquine prophylaxis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2006-001347-66 Sponsor Protocol Number: A0081092 Start Date*: 2006-08-18
    Sponsor Name:Pfizer España
    Full Title: A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF PREGABALIN IN SUBJECTS WITH GENERALIZED ANXIETY DISORDER (GAD) SWITCHING FROM BENZODIAZEPINE THERAPY Estudio multicéntrico, alea...
    Medical condition: Generalized Anxiety Disorder
    Disease: Version SOC Term Classification Code Term Level
    8.1 10018105 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2019-003787-48 Sponsor Protocol Number: BP41674 Start Date*: 2020-06-11
    Sponsor Name:F. Hoffmann-La Roche
    Full Title: AN OPEN-LABEL, MULTICENTER STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF RO7248824 IN PARTICIPANTS WITH ANGELMAN SYNDROME
    Medical condition: Angelman Syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10049004 Angelman's syndrome PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) NL (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-006168-31 Sponsor Protocol Number: E2007-G000-305 Start Date*: 2008-08-28
    Sponsor Name:Eisai Ltd
    Full Title: A Double-Blind, Placebo-Controlled, Dose-Escalation, Parallel-Group Study to Evaluate the Efficacy and Safety of E2007 (perampanel) Given as Adjunctive Therapy in Subjects with Refractory Partial S...
    Medical condition: Epilepsy: refractory partial seizures with or without secondary generalisation
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) BE (Completed) NL (Completed) DE (Completed) FR (Completed) SE (Completed) GB (Completed) DK (Completed) FI (Completed) IT (Completed) GR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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