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Clinical trials for Wet AMD AND Age-Related Macular Degeneration

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44398   clinical trials with a EudraCT protocol, of which   7410   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    107 result(s) found for: Wet AMD AND Age-Related Macular Degeneration. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2010-021777-37 Sponsor Protocol Number: Lucentis-LucERG Start Date*: 2010-09-27
    Sponsor Name:Universitätsklinikum Schleswig-Holstein (UK-SH)
    Full Title: "A prospective, non-randomized, mono-center, cohort study to evaluate the short- and long-term effects of 0.5mg intraocular Ranibizumab (Lucentis) injections on retinal function in patients with we...
    Medical condition: Retinal function in patients with wet age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    12.1 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017435-18 Sponsor Protocol Number: CLIN905 MLT202 Start Date*: 2010-02-04
    Sponsor Name:Steba Biotech S.A.
    Full Title: A Phase IIa, Safety and Preliminary Effects Study of WST11 (Stakel®)-Mediated Vascular-Targeted Photodynamic (VTP) Therapy in Subjects with Choroidal Neovasularization (CNV) Associated with Age-Rel...
    Medical condition: Age associated Macular Degeneration
    Disease: Version SOC Term Classification Code Term Level
    12.1 10064930 Age-related macular degeneration LLT
    12.1 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005500-18 Sponsor Protocol Number: VITCLEAR Start Date*: 2013-11-18
    Sponsor Name:King's College Hospital NHS Foundation Trust [...]
    1. King's College Hospital NHS Foundation Trust
    2. King's College London
    Full Title: A pharmacokinetic study: ranibizumab, aflibercept and the effect of vitrectomy
    Medical condition: Age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    17.0 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    17.0 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-024001-12 Sponsor Protocol Number: LuMi-1 Start Date*: 2011-01-27
    Sponsor Name:TYKS
    Full Title: The effect of bevacizumab treatment on reading ability in age related macular degeneration
    Medical condition: Age related macular degeneration of the eye, wet form
    Disease: Version SOC Term Classification Code Term Level
    12.1 10064930 Age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003763-22 Sponsor Protocol Number: BAY73-4506/15984 Start Date*: 2014-07-02
    Sponsor Name:Bayer HealthCare AG
    Full Title: A combined Phase IIa / IIb study of the efficacy, safety, and tolerability of repeated topical doses of regorafenib eye drops, in treatment-naïve subjects with neovascular age related macular degen...
    Medical condition: neovascular age related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    18.0 10015919 - Eye disorders 10071129 Neovascular age-related macular degeneration PT
    18.0 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    18.0 10015919 - Eye disorders 10025409 Macular degeneration PT
    18.0 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) DE (Prematurely Ended) CZ (Prematurely Ended) SK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006312-30 Sponsor Protocol Number: MACPED-06-01 Start Date*: 2007-04-05
    Sponsor Name:Dept. of Ophthalmol, Semmelweis University
    Full Title: A phase IV non-randomized, uncontrolled, open-label, single-center trial to evaluate the safety and efficacy of Macugen (pegaptanib sodium) given by intravitreal injections every 6 weeks in patient...
    Medical condition: neovascular (wet) age-related macular degeneration (AMD)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10025411 Macular degeneration senile LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000518-23 Sponsor Protocol Number: OPH1007 Start Date*: 2015-10-20
    Sponsor Name:OPHTHOTECH CORPORATION
    Full Title: A phase 2b randomized, double-masked, controlled trial to establish the safety and efficacy of intravitreous administration of Fovista® (Anti-PDGFBB pegylated aptamer) administered in combination w...
    Medical condition: Subfoveal neovascular age-related macular degeneration (AMD)
    Disease: Version SOC Term Classification Code Term Level
    18.1 10015919 - Eye disorders 10071129 Neovascular age-related macular degeneration PT
    18.1 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) EE (Prematurely Ended) CZ (Prematurely Ended) HR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015681-55 Sponsor Protocol Number: C-09-023 Start Date*: 2010-03-18
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A Dose-Escalation Study of AL-39324 Suspension versus Lucentis™ for the Treatment of Exudative Age-Related Macular Degeneration
    Medical condition: Exudative Age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    14.0 10015919 - Eye disorders 10025409 Macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-018637-21 Sponsor Protocol Number: 1 Start Date*: 2013-11-20
    Sponsor Name:Universitätsklinikum Schleswig-Holstein UKSH
    Full Title: Intravitreal Injection of Lucentis (Ranibizumab) after Pars Plana Vitrectomy and Subretinal Application of Recombinant Tissue Plasminogen Activator (rtPA) in Patients with Acute Submacular Hemorrha...
    Medical condition: exsudative age-related macular degeneration with acut submacular hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004853 10055305 Macula lutea hemorrhage LLT
    16.1 100000004853 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-005091-17 Sponsor Protocol Number: 26285/13 Start Date*: 2014-02-05
    Sponsor Name:POLICLINICO GEMELLI
    Full Title: Variation of choroidal Thickness 15 days after the first ranibizumab intravitreal injection in naïve patients WIth Neovascular age-related macular degeneration: pilot Study. –
    Medical condition: Wet age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004853 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004078-24 Sponsor Protocol Number: TAPAS Start Date*: 2013-01-24
    Sponsor Name:King's College London [...]
    1. King's College London
    2. King's College Hospital NHS Foundation Trust
    Full Title: Intravitreal Tissue Plasminogen Activator (tPA), Perfluoropropane (C3F8), and Ranibizumab for Neovascular Age-Related Macular Degeneration and Submacular Haemorrhage (TAPAS): A Randomized, Double-M...
    Medical condition: Sub-macular haemorrhage secondary to wet macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    16.0 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    16.0 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002168-34 Sponsor Protocol Number: FNB-OK-2013-01 Start Date*: 2014-12-09
    Sponsor Name:Doc. MUDr. Petr Kolář, PhD, Oční klinika FN Brno
    Full Title: Study To Determine Efficacy of Aflibercept For Treatment Of Retinal Angiomatous Proliferation Secondary To Age Related Macular Degeneration
    Medical condition: Retinal angiomatous proliferation secondary to wet age related macular degeneration.
    Disease: Version SOC Term Classification Code Term Level
    17.0 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    17.0 10015919 - Eye disorders 10069125 Retinal angiomatous proliferation LLT
    17.0 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004567-30 Sponsor Protocol Number: 1313.20 Start Date*: 2014-04-15
    Sponsor Name:Boehringer Ingelheim RCV GmbH & Co KG
    Full Title: A single arm open label study to evaluate the pharmacodynamics and safety of a 4 wk treatment with BI 144807 in patients with newly diagnosed wet age related macular degeneration (wAMD)
    Medical condition: patients with newly diagnosed, unilateral, wet Are-Related Macular Degeneration
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004853 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) DE (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-018741-65 Sponsor Protocol Number: OPH1001A Start Date*: 2010-04-21
    Sponsor Name:OPHTHOTECH CORPORATION
    Full Title: A PHASE 2, RANDOMIZED, DOUBLE-MASKED, CONTROLLED TRIAL TO ESTABLISH THE SAFETY AND EFFICACY OF INTRAVITREOUS INJECTIONS OF E10030 (ANTI-PDGF PEGYLATED APTAMER) GIVEN IN COMBINATION WITH LUCENTIS® I...
    Medical condition: Subfoveal choroidal neovascularization secondary to age-related macular degeneration (AMD)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    14.1 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) FR (Completed) BE (Completed) DE (Completed) ES (Completed) HU (Completed) IT (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-003333-15 Sponsor Protocol Number: CRFB002AIT02 Start Date*: 2013-11-15
    Sponsor Name:NOVARTIS FARMA
    Full Title: A 12 months, prospective, multicenter, open-label, single arm interventional study assessing the safety and tolerability of 0.5 mg ranibizumab in mono/bilateral wet AMD patients in eyes with BCVA b...
    Medical condition: Mono/bilateral Wet Age related Macular Degeneration (wAMD) in eyes with Best Corrected Visual Acuity (BCVA) below 2/10 and/or second affected eye .
    Disease: Version SOC Term Classification Code Term Level
    16.0 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-000379-41 Sponsor Protocol Number: RLBUHT3407 Start Date*: 2007-05-22
    Sponsor Name:Royal Liverpool & Broadgreen University hospital
    Full Title: Liverpool Avastin Dose Response and Retreatment Study
    Medical condition: Exudative senile macular degeneration of the retina
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015902 Exudative senile macular degeneration of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000103-27 Sponsor Protocol Number: Eylea-2014 Start Date*: 2014-03-12
    Sponsor Name:
    Full Title: Plasma levels of vascular endothelial growth factor before and after intravitreal injection of aflibercept in patients with exudative age-related macular degeneration.
    Medical condition: Exudative age-related macular degeneration (AMD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006290-90 Sponsor Protocol Number: AU-06102G Start Date*: 2008-10-10
    Sponsor Name:Society (Institute) for clinical research
    Full Title: Subretinal Macugen for neovascular age-related macular degeneration (SUMANA)
    Medical condition: Neovascular (exudative) age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015902 Exudative senile macular degeneration of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002526-43 Sponsor Protocol Number: 150998-001 Start Date*: 2012-01-30
    Sponsor Name:Allergan Limited
    Full Title: Single and Repeat Dose Study of the Safety and Efficacy of AGN-150998 in Patients with Exudative Age-related Macular Degeneration
    Medical condition: Exudative Age-related Macular Degeneration
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10025411 Macular degeneration senile LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-003018-42 Sponsor Protocol Number: OPH1004 Start Date*: 2014-10-10
    Sponsor Name:OPHTHOTECH CORPORATION
    Full Title: A phase 3 randomized, double-masked, controlled trial to establish the safety and efficacy of intravitreous administration of Fovista™ (Anti PDGF-B pegylated aptamer) administered in combination wi...
    Medical condition: Subfoveal neovascular age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10071129 Neovascular age-related macular degeneration PT
    20.1 10015919 - Eye disorders 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Prematurely Ended) ES (Prematurely Ended) FI (Completed) NO (Completed) DE (Prematurely Ended) EE (Prematurely Ended) LV (Prematurely Ended) SK (Prematurely Ended) IT (Completed) AT (Prematurely Ended) HU (Completed) HR (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: View results
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