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Clinical trials for Placebo comparator

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44343   clinical trials with a EudraCT protocol, of which   7372   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,804 result(s) found for: Placebo comparator. Displaying page 10 of 91.
    EudraCT Number: 2014-003121-17 Sponsor Protocol Number: DU001 Start Date*: 2014-09-09
    Sponsor Name:D.A.S.T. BIOTECH PHARM Ε.Π.Ε.
    Full Title: Randomized, double-blind intervention study of efficacy and safety of the product Vioplex-T compared with placebo in patients with open sores (pressure ulcers).
    Medical condition: Pressured Ulcers in I & II
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-005354-20 Sponsor Protocol Number: 12710A Start Date*: 2016-03-15
    Sponsor Name:H. Lundbeck A/S
    Full Title: Interventional, randomised, double-blind, placebo-controlled, active reference (fluoxetine), fixed-dose study of vortioxetine in paediatric patients aged 12 to 17 years, with Major depressive disor...
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    19.1 10037175 - Psychiatric disorders 10057840 Major depression PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: LV (Completed) EE (Completed) GB (Completed) HU (Completed) BG (Completed) DE (Completed) FI (Not Authorised) IT (Completed) ES (Completed) BE (Completed) PL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2014-005117-23 Sponsor Protocol Number: 1311.3 Start Date*: 2016-04-14
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: BI 655066/ABBV-066 (risankizumab) versus Ustekinumab and placebo comparators in a randomized double blind trIal for Maintenance use in Moderate to severe plaque type psoriasis (UltIMMa-1)
    Medical condition: Psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2014-004586-24 Sponsor Protocol Number: ESKETINTRD3003 Start Date*: 2015-09-22
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Double-blind, Multicenter, Active-Controlled Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Treatment-resistant Depression
    Medical condition: Treatment-resistant Major Depression
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10057840 Major depression PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) PL (Completed) ES (Completed) HU (Completed) CZ (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001379-20 Sponsor Protocol Number: 009 Start Date*: 2018-05-23
    Sponsor Name:Myovant Sciences GmbH
    Full Title: A Phase 2a Randomized, Double-Blind, Placebo and Active Comparator-Controlled, Parallel Group, Dose-Range Finding Study of MVT-602 in Healthy Premenopausal Women Undergoing Controlled Ovarian Stimu...
    Medical condition: Female infertility
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10021935 Infertility, female, associated with anovulation LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2004-001404-12 Sponsor Protocol Number: MSRORDAH-01/03 Start Date*: Information not available in EudraCT
    Sponsor Name:Laboratorios Rubió, S.A.
    Full Title: Estudio prospectivo, aleatorizado, doble ciego, para la evaluación de la eficacia y seguridad del metilfenidato de liberación prolongada con respecto al metilfenidato de liberación inmediata y plac...
    Medical condition: Niños con trastorno por déficit de atención con hiperactividad
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023875-24 Sponsor Protocol Number: CRO1777 Start Date*: 2011-02-23
    Sponsor Name:AHSC Joint Research Office, Imperial College
    Full Title: Anglo-Scandinavian Cardiac Outcomes Trial; Post Trial Follow-Up Study
    Medical condition: Hypertension, cardiovascular disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-004794-41 Sponsor Protocol Number: Vista Start Date*: 2017-03-02
    Sponsor Name:Academical medical centre, dep of internal medicine
    Full Title: Arterial wall inflammation measured with 18F-FDG PET/CT in patients with statin intolerance before and after treatment with a PCSK-9 inhibitor
    Medical condition: Patients with CV-risk and statin intolerance due to statin-associated muscle symptoms (SAMS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000779-26 Sponsor Protocol Number: ECABUSCA12 Start Date*: 2014-08-19
    Sponsor Name:Asociación Instituto Biodonostia
    Full Title: Efficacy of subcutaneous butylscopolamine vs placebo for control to death rattle in agony. Randomized clinical trial.
    Medical condition: phase of agony, pre-death
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-016827-72 Sponsor Protocol Number: GAL-Moa-003 Start Date*: 2010-01-12
    Sponsor Name:Galenica AB
    Full Title: A multicentre, randomized, double-blind, safety and efficacy non-inferiority, intra-individual study, comparing Mometasone furoate Galenica 0.1% cream with Elocon 0.1% cream and placebo in patients...
    Medical condition: Mild to moderate plaque psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2012-003281-40 Sponsor Protocol Number: 2712 Start Date*: 2012-10-23
    Sponsor Name:Universitätsklinikum Freiburg
    Full Title: Efficacy of gencydo nasal spray on early nasal response after allergen exposition in patients with grass pollen allergy: a randomized, placebo controlled cross over study
    Medical condition: Hay fever caused by grass pollen allergy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004825-42 Sponsor Protocol Number: Notapplicablenow Start Date*: 2016-12-22
    Sponsor Name:ACTA
    Full Title: Effect of Delmopinol on treatment of Peri - implant mucositis : a randomised controlled clinical trial
    Medical condition: Peri implant mucositis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-004665-25 Sponsor Protocol Number: TCC-C-001 Start Date*: 2008-09-04
    Sponsor Name:MUTUAL PHARMACEUTICAL COMPANY
    Full Title: A SINGLE BLIND, SINGLE DOSE STUDY OF THE SEDATIVE EFFECTS OF THIOCOLCHICOSIDE, TIZANIDINE AND CYCLOBENZAPRINE IN HEALTHY MALE, HUMAN VOLUNTEERS
    Medical condition: muscle spasm
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028393 Musculoskeletal and connective tissue disorders NEC HLGT
    Population Age: Adults Gender: Male
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005640-81 Sponsor Protocol Number: RR06/7719 Start Date*: 2007-09-04
    Sponsor Name:University of Leeds
    Full Title: A PLACEBO CONTROLLED STUDY OF THE EFFECT OF EXTENDED TREATMENT WITH RITUXIMAB ON RESISTANT RHEUMATOID ARTHRITIS:
    Medical condition: Rheumatoid arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004899-30 Sponsor Protocol Number: 111187 Start Date*: 2016-12-21
    Sponsor Name:GlaxoSmithKline Research & Development Ltd.
    Full Title: Multi-center, Randomised, Double-blind, Parallel, Placebo Controlled Study Of 0.05% Clobetasone Butyrate Cream in Subjects with Eczema to evaluate the Efficacy and Safety.
    Medical condition: Eczema
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-004859-35 Sponsor Protocol Number: 250518BS Start Date*: 2006-06-07
    Sponsor Name:G&W Laboratories, Inc.
    Full Title: Determination of antipsoriatic efficacy of topical formulations and comparison to a brand medication and placebo in a psoriasis plaque test
    Medical condition: Male or female subjects aged 18 to 64 are eligible for the study insofar that they suffer from chronic plaque type psoriasis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006619-64 Sponsor Protocol Number: 2006SG005 Start Date*: 2007-07-04
    Sponsor Name:University Hospital of South Manchester NHS Foundation Trust [...]
    1. University Hospital of South Manchester NHS Foundation Trust
    2. University of Manchester
    Full Title: Randomised Controlled Trial of Lapatinib (A Her1/2 Tyrosine Kinase Inhibitor) on Epithelial Proliferation and Apoptosis in Ductal Cancer in Situ.
    Medical condition: Women with a core biopsy diagnosis of histologically proven Her2 positive DCIS (or DCIS and invasive cancer). Women undergoing re-excision of DCIS will be eligible provided residual DCIS is presen...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065430 HER-2 positive breast cancer LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-006842-25 Sponsor Protocol Number: 2008_19\0838 Start Date*: 2009-04-17
    Sponsor Name:CHRU de Lille
    Full Title: Etude monocentrique randomisée en double aveugle versus placebo avec deux groupes parallèles d’efficacité et de tolérance de la défériprone (traitement chélateur de fer) sur la surcharge cérébrale ...
    Medical condition: Maladie de Parkinson
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002910-39 Sponsor Protocol Number: NC19453 Start Date*: 2006-07-31
    Sponsor Name:F. Hoffmann-La Roche Ltd.
    Full Title: A Phase II, Double-Blind, Randomized, Placebo-controlled, Parallel Group Study, Evaluating the Efficacy and Safety of RO4607381 over a 24-week period in Patients with CHD or a CHD Risk Equivalent
    Medical condition: CHD or CHD Risk Equivalent
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005704-15 Sponsor Protocol Number: ATF-EGD001 Start Date*: 2012-01-02
    Sponsor Name:Hospital Universitario Infanta Cristina
    Full Title: Usefulness of lidocaine as topical pharyngeal anaesthesia in esophagogastroduodenoscopy under sedation with propofol
    Medical condition: Propofol´s mean dosage in routinely esophagogastroduodenoscopy with and without topical pharyngeal anaesthesia with lidocaine. Variation between the patient´s groups in side effects and endoscopist...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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