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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,347 result(s) found. Displaying page 1,120 of 2,218.
    EudraCT Number: 2016-002648-18 Sponsor Protocol Number: 2016-34 Start Date*: 2017-04-28
    Sponsor Name:ASSISTANCE PUBLIQUE HOPITAUX MARSEILLE
    Full Title: “EVALUATION OF AN INNOVATIVE TREATMENT FOR RADIOCARPAL OSTEOARTHRITIS USING INTRA-ARTICULAR INJECTION OF A MIXTURE OF AUTOLOGOUS MICROFAT AND AUTOLOGOUS PLATELET-RICH PLASMA”
    Medical condition: Symptomatic radio-carpal osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003710-58 Sponsor Protocol Number: 57238 Start Date*: 2018-07-17
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA POLICLINICO “PAOLO GIACCONE” DI PALERMO
    Full Title: Study to Investigate the Efficacy of elbasvir/grazoprevir Fixed-Dose Combination for 8 Weeks in G1b Treatment-Na¿ve, HCV-Infected Patients With non-severe Fibrosis, with or without glucose abnorm...
    Medical condition: chronic hepatitis C
    Disease: Version SOC Term Classification Code Term Level
    20.0 10019805 - Hepatobiliary disorders 10019805 Hepatobiliary disorders SOC
    20.0 10021881 - Infections and infestations 10021881 Infections and infestations SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004318-14 Sponsor Protocol Number: NEOD001-201 Start Date*: 2016-06-13
    Sponsor Name:Prothena Therapeutics Limited
    Full Title: A Phase 2b, Randomized, Double-blind, Placebo-controlled Study of NEOD001 in Previously Treated Subjects with Light Chain (AL) Amyloidosis who have Persistent Cardiac Dysfunction
    Medical condition: Light chain (AL) amyloidosis involves a hematologic disorder caused by clonal plasma cells that produce misfolded immunoglobulin light chains. Overproduction of misfolded light chains results in bo...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021428 - Immune system disorders 10036673 Primary amyloidosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Completed) GR (Completed) ES (Prematurely Ended) AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-000917-59 Sponsor Protocol Number: ARCAAT2001 Start Date*: 2016-06-29
    Sponsor Name:Arrowhead Pharmaceuticals, Inc
    Full Title: An Open-Label, Multi-dose, Phase 2 Study to Determine the Safety, Tolerability and Effect on Circulating and Intrahepatic Alpha-1 Antitrypsin Levels of ARC-AAT as evidenced by changes in liver biop...
    Medical condition: Alpha-1 Antitrypsin Deficiency related liver disease
    Disease: Version SOC Term Classification Code Term Level
    19.1 10010331 - Congenital, familial and genetic disorders 10001806 Alpha-1 anti-trypsin deficiency PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended) SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-004025-14 Sponsor Protocol Number: GS-US-380-1844 Start Date*: 2016-02-18
    Sponsor Name:Gilead Science, Inc.
    Full Title: A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Switching from a Regimen of Dolutegravir and ABC/3TC, or a Fixed Dose Combination (FDC) of ABC/DTG/3TC to a FDC of G...
    Medical condition: Human Immunodeficiency Virus (HIV-1) Infection
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10068341 HIV-1 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2015-005616-14 Sponsor Protocol Number: M13-596 Start Date*: 2016-05-31
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of ABT-493/ABT-530 in Adult Post-Liver or Post-Renal Transplant Recipients with Chronic Hepatitis C Virus Genotype 1 ...
    Medical condition: Hepatitis C Virus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-000411-91 Sponsor Protocol Number: NKZellen-Version1.0 Start Date*: 2013-02-13
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: Monitoring natural killer cells in multiple sclerosis patients treated with fingolimod: a monocentric, prospective, one year, baseline-to-treatment, open-label, single group pilot trial
    Medical condition: relapsing-remitting multiple sclerosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-003259-39 Sponsor Protocol Number: NeuroClin02 Start Date*: 2014-03-28
    Sponsor Name:Neurochlore
    Full Title: A Phase II dose ranging study of Bumetanide solution in children and adolescents with autism spectrum disorders.
    Medical condition: Diseases and Related Health Problems, tenth revision (ICD-10) and with a Childhood Autism Rating Scale (CARS) score > 34.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-010062-33 Sponsor Protocol Number: ABH-DERMAGRAFT-001-08 Start Date*: 2009-09-24
    Sponsor Name:Advanced BioHealing Inc
    Full Title: A Prospective, Multi-center, Randomized, Controlled Clinical Investigation of Dermagraft® in Subjects with Venous Leg Ulcers
    Medical condition: Venous leg ulcers
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024134 Leg ulcer (exc varicose) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) GB (Completed) EE (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-000408-39 Sponsor Protocol Number: 1487-0003 Start Date*: 2021-06-02
    Sponsor Name:SCS Boehringer Ingelheim Comm. V
    Full Title: A Phase III randomized, double-blind, placebo-controlled, parallel-group, group-sequential study to evaluate efficacy, safety and tolerability of BI 767551 for post-exposure prevention of SARS-CoV-...
    Medical condition: COVID-19
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023528-25 Sponsor Protocol Number: 2010-023528-25 Start Date*: 2010-12-23
    Sponsor Name:CHU Brugmann
    Full Title: Etude clinique prospective randomisée en double aveugle de phase 4 comparant la durée d'analgésie postopératoire du fentanyl et du sufentanil administrés comme adjuvant en rachianesthésie dans le c...
    Medical condition: Pregnant patients with a planned caesarian.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10067385 Spinal analgesia LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-004505-14 Sponsor Protocol Number: Modic02 Start Date*: 2015-03-04
    Sponsor Name:Oslo University Hospital HF, Ullevål Hospital, FORMI-Formidlingsenheten for muskel- og skjelettlidelser
    Full Title: Antibiotic treatment in patients with chronic low back pain and Modic Changes: a double-blind randomized placebo-controlled trial
    Medical condition: A recent Danish study published during spring 2013 advances a remarkable cause and treatment with Amoxicillin for a selected sub-group of low back pain patients.The study was based upon a hypothesi...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2007-000579-40 Sponsor Protocol Number: D1443L00002 Start Date*: 2007-10-10
    Sponsor Name:Charité Universitätsmedizin Berlin
    Full Title: Effects of atypical versus typical neuroleptics on motivation, hedonia, and social cognition in patients with schizophrenia – an fMRI study
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039626 Schizophrenia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001732-53 Sponsor Protocol Number: ADUR-Studie Start Date*: 2006-08-16
    Sponsor Name:University Hospital of Heidelberg
    Full Title: Eine multizentrische, randomisierte, kontrollierte Studie zur Untersuchung von Adalimumab bei der Behandlung verschiedener Formen von refraktärer Uveitis im Vergleich zur Standardtherapie Randomiz...
    Medical condition: Adalimumab in treatment of refractory uveitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10046851 Uveitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001212-72 Sponsor Protocol Number: MIR Start Date*: 2007-06-13
    Sponsor Name:University Hospital of Heidelberg
    Full Title: Therapie des nodalen Follikulären Non-Hodgkin-Lymphoms (WHO Grad I/II) im klinischen Stadium I / II mittels involved-field Bestrahlung in Kombination mit Rituximab (Mabthera Involved-field Radiothe...
    Medical condition: nodal follicular non-Hodgkin´s Lymphoma (WHO Grade I/II) in clinical stage I/II
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029603 Non-Hodgkin's lymphoma stage II PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029602 Non-Hodgkin's lymphoma stage I PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005699-33 Sponsor Protocol Number: 12-179 Start Date*: 2013-07-22
    Sponsor Name:CHU Caen
    Full Title: Etude de la pharmacocinétique de la daptomycine en administration intrapéritonéale chez les patients en dialyse péritonéale présentant une infection péritonéale.
    Medical condition: renal failure
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022117 - Injury, poisoning and procedural complications 10067594 Peritoneal dialysis complication PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-000654-38 Sponsor Protocol Number: AHUS2015-000654-38 Start Date*: 2015-10-19
    Sponsor Name:Akershus University Hospital, Norway
    Full Title: Secondary prophylaxis after hip fracture. An evaluation og two organisational models based on choise of treatment: a comparison of efficacy and applicability of hospital based treatment with zoled...
    Medical condition: Hip fracture
    Disease: Version SOC Term Classification Code Term Level
    17.1 10022117 - Injury, poisoning and procedural complications 10020100 Hip fracture PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-003755-21 Sponsor Protocol Number: ISIS304801-CS7 Start Date*: 2016-06-06
    Sponsor Name:Akcea Therapeutics
    Full Title: An Open-Label Study of Volanesorsen Administered Subcutaneously to Patients with Familial Chylomicronemia Syndrome (FCS)
    Medical condition: Familial Chylomicronemia Syndrome (FCS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10017339 Fredrickson Type I lipidaemia LLT
    20.0 100000004850 10060593 Fredrickson Type I lipidemia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) NL (Completed) ES (Completed) DE (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-000457-36 Sponsor Protocol Number: 14-006 Start Date*: 2015-03-10
    Sponsor Name:CHU CAEN
    Full Title: A comparative dynamic study of myocardial perfusion reserve explored by cardiac WATER labelled O-15 -PET vs Tc99mibi D-SPECT in coronAry arterY disease. Protocol WATER -DAY
    Medical condition: Patient suspect d’une maladie coronaire et/ou syndrome coronarien ST-
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004849 10011099 Coronary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2016-001841-23 Sponsor Protocol Number: I.2016.010 Start Date*: 2016-11-16
    Sponsor Name:Banc de Sang i Teixits
    Full Title: A multicenter, randomized, open-label, two-arms phase I/II clinical trial to asses efficacy and safety of cord blood eye drops in neurotrophic keratopathy
    Medical condition: Neurotrophic Keratitis, stage 2 or 3
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10064996 Ulcerative keratitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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