Clinical trials

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC

clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).

The EU Clinical Trials Register currently displays 44346 clinical trials with a EudraCT protocol, of which 7374 are clinical trials conducted with subjects less than 18 years old. The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).

Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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Trials with a EudraCT protocol (44,346)
Paediatric studies in scope of Art45 of the Paediatric Regulation (0)

44,346 result(s) found. Displaying page 1,806 of 2,218.

EudraCT Number: 2019-002442-20

Sponsor Protocol Number: 2019/2886

Start Date*: 2020-02-15

Sponsor Name:Gustave Roussy

Full Title: Study evaluating near infrared imaging coupled with indocyanine green for preoperative control of resection margins in ENT surgery.

Medical condition: visualization of the resection margins by near infrared fluorescence imaging (in vivo and ex vivo) for patients over 18 years of age with ENT epidermoid cancer treated by open surgery or by robot-a...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10067821	Head and neck cancer	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2015-005053-12

Sponsor Protocol Number: MK3475-204

Start Date*: 2016-06-01

Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.

Full Title: A Phase III, Randomized, Open-label, Clinical Trial to Compare Pembrolizumab with Brentuximab Vedotin in Subjects with Relapsed or Refractory Classical Hodgkin Lymphoma

Medical condition: Relapsed or refractory classical Hodgkin lymphoma

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004864	10020328	Hodgkin's lymphoma	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SE (Trial now transitioned) DE (Trial now transitioned) PL (Trial now transitioned) FR (Trial now transitioned) CZ (Trial now transitioned) GB (GB - no longer in EU/EEA)

Trial results: (No results available)

EudraCT Number: 2022-001838-11	Sponsor Protocol Number: APHP211055	Start Date*: 2022-10-20
Sponsor Name:APHP DRCI
Full Title: Evaluation of low dose colchicine and ticagrelor in prevention of ischemic stroke in patients with stroke due to atherosclerosis. “Reducing inflammation in ischemic stroke with colchicine (riisc),...
Medical condition: Evaluation of low dose colchicine and ticagrelor in prevention of ischemic stroke in patients with stroke due to atherosclerosis
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FR (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2021-000252-18

Sponsor Protocol Number: 35RC20_9803_RePERSO

Start Date*: 2021-04-27

Sponsor Name:Rennes University Hospital

Full Title: Evaluation of treatment PERSOnalization based on its therapeutic monitoring in patients with metastatic colorectal cancer treated with regorafenib

Medical condition: metastatic colorectal cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	100000004864	10052362	Metastatic colorectal cancer	LLT

Population Age: Adults

Gender: Male, Female

Trial protocol: FR (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2022-000174-25

Sponsor Protocol Number: 101090401IN

Start Date*: 2023-03-17

Sponsor Name:SANTEN INCORPORATED

Full Title: A Phase IIa, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared with Vehi...

Medical condition: Fuchs Endothelial Corneal Dystrophy (FECD)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004850	10014823	Endothelial corneal dystrophy	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2021-002588-23

Sponsor Protocol Number: 2019/0407/HP

Start Date*: 2023-03-13

Sponsor Name:CHU de Rouen

Full Title: Neoadjuvant Chemotherapy for Obstructive Colon cancER first Treated by cOlostomy: A randomized phase III trial - COnCERTO (French 01-18)

Medical condition: Patients first treated by stoma and requiring chemotherapy for obstructive colon cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10009944	Colon cancer	PT
	20.0	10042613 - Surgical and medical procedures	10073254	Neoadjuvant therapy	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2021-005146-15

Sponsor Protocol Number: NIPIRESCUE_G-113

Start Date*: 2021-12-22

Sponsor Name:GERCOR

Full Title: Nivolumab and ipilimumab in patients with dMMR and/or MSI metastatic colorectal cancer resistant to anti-PD1 monotherapy: An open-label phase II GERCOR trial (NIPIRESCUE)

Medical condition: dMMR and/or MSI metastatic colorectal cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10052358	Colorectal cancer metastatic	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2018-001960-45	Sponsor Protocol Number: RC18_0206	Start Date*: 2019-04-15
Sponsor Name:CHU of Nantes
Full Title: An intensive program with quadruplet induction and consolidation plus tandem autologous stem cell transplantation in Newly Diagnosed High Risk Multiple Myeloma Patients: a phase II study of the Int...
Medical condition: Young untreated patients with multiple myeloma
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FR (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2022-002563-29	Sponsor Protocol Number: APHP211429	Start Date*: 2023-04-18
Sponsor Name:Assistance Publique – Hôpitaux de Paris (AP-HP)
Full Title: Colchicine versus Placebo in Acute Myocarditis Patients to Reduce Late Gadolinium Enhancement Mass on Cardiac Magnetic Resonance and the risk of Clinical Outcomes: The ARGO tria
Medical condition: NA
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: FR (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2020-003318-10

Sponsor Protocol Number: D20180135

Start Date*: 2021-08-05

Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)

Full Title: Evaluation of MEpolizumab-based regimen Compared to Conventional Therapeutic Strategy For Remission Induction In Patients With Eosinophilic Granulomatosis With Polyangiitis. Prospective, randomized...

Medical condition: Patients with a diagnosis of Eosinophilic Granulomatosis with Polyangiitis (EGPA) with newly-diagnosed disease or with a relapsing disease at the time of screening

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10021428 - Immune system disorders	10078117	Eosinophilic granulomatosis with polyangiitis	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2017-004175-31	Sponsor Protocol Number: Prucalopride2017	Start Date*: 2018-04-09
Sponsor Name:TARGID, KU Leuven
Full Title: A placebo-controlled trial with prucalopride for the treatment of typical reflux symptoms in patients with gastro-esophageal reflux disease with incomplete proton pump inhibitor response
Medical condition: refractory gastro-esophageal reflux disease
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: BE (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2017-001197-42	Sponsor Protocol Number: 2017-01	Start Date*: 2017-05-15
Sponsor Name:ASSISATNCE PUBLIQUE HOPITAUX DE MARSEILLE
Full Title: Evolution of the cardiac function(office) during the follow-up of the anticancer immunotherapy inhibiting PD-1
Medical condition: as melanoma, non-small cell lung cancers and kidney cancers
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FR (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2017-001371-24	Sponsor Protocol Number: 6621	Start Date*: 2019-01-08
Sponsor Name:Hôpitaux Universitaires de Strasbourg
Full Title: Prospective, randomised, placebo-controlled study of polyvalent intravenous immunoglobulins for the treatment of primary Sjögren's syndrome associated painful sensory neuropathies
Medical condition: Primary Sjögren's syndrome associated painful sensory neuropathies
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FR (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2020-004633-21	Sponsor Protocol Number: APHP191047	Start Date*: 2024-04-29
Sponsor Name:Assistance Publique -Hopitaux de Paris
Full Title:
Medical condition:
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FR (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2021-005508-37	Sponsor Protocol Number: PI2021_843_0197	Start Date*: 2021-12-20
Sponsor Name:CHU Amiens-Picardie
Full Title: Evaluation of plasma concentrations of intravenous lidocaine and epidural ropivacaine when used in combination in major abdominal surgery
Medical condition: major abdominal surgery
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FR (Completed)
Trial results: (No results available)

EudraCT Number: 2019-002376-14	Sponsor Protocol Number: ELLOUZE_ORION_2018	Start Date*: 2019-10-15
Sponsor Name:CHU Dijon Bourgogne
Full Title:
Medical condition:
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FR (Prematurely Ended)
Trial results: (No results available)

EudraCT Number: 2012-000259-14	Sponsor Protocol Number: 1/2012AITT	Start Date*: 2012-08-31
Sponsor Name:University of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
Full Title: Reversal of residual pipecuronium neuromuscular block using sugammadex: a randomized, double-blind, placebo controlled, dosefinding study
Medical condition: The effect of sugammadex dose on residual neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle rel...
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: HU (Completed)
Trial results: (No results available)

EudraCT Number: 2013-001965-17

Sponsor Protocol Number: AITT2013/5

Start Date*: 2013-09-26

Sponsor Name:Debreceni Egyetem Orvos- és Egészségtudományi Centrum Aneszteziológiai és Intenzív Terápiás Tanszék

Full Title: Incidence of postoperative residual neuromuscular blockade following the administration of rocuronium: A randomized placebo controlled study.

Medical condition: The effect of sugammadex and neostigmin on postoperative residual neuromuscular blockade will be investigated, therefore the patients suffering from various conditions undergoing surgery in general...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	16.0	10042613 - Surgical and medical procedures	10057286	Neuromuscular blockade reversal	PT

Population Age: Adults

Gender: Male, Female

Trial protocol: HU (Completed)

Trial results: (No results available)

EudraCT Number: 2021-004320-16

Sponsor Protocol Number: 77242113PSO2002

Start Date*: 2022-07-05

Sponsor Name:Janssen-Cilag International NV

Full Title: A Phase 2b Multicenter, Long-Term Extension, Dose-ranging Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis

Medical condition: Plaque Psoriasis

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004858	10071117	Plaque psoriasis	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed) ES (Ongoing) PL (Completed)

Trial results: View results

EudraCT Number: 2019-003459-12

Sponsor Protocol Number: RB-NAIT-01-01

Start Date*: 2020-08-11

Sponsor Name:Rallybio, IPA, LLC

Full Title: A Single-blind, Placebo-controlled, Single-center Study Investigating the Dose of Human Anti-Human Platelet Antigen (HPA)-1a Immune Globulin (NAITgam) Needed to Eliminate HPA-1a Positive Platelets ...

Medical condition: prevention of Fetal Neonatal Alloimmune Thrombocytopenia (FNAIT In mothers negative for HPA-1a antigen, fetal platelets positive for HPA-1a antigen, may enter the mother’s circulation and induce pr...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.1	100000004850	10075151	Fetal and neonatal alloimmune thrombocytopenia	LLT

Population Age: Adults

Gender: Male

Trial protocol: DE (Completed)

Trial results: View results

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The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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