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Clinical trials for Acute Kidney Injury

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    161 result(s) found for: Acute Kidney Injury. Displaying page 2 of 9.
    « Previous 1  2  3  4  5  6  7  8  9  Next»
    EudraCT Number: 2022-003000-32 Sponsor Protocol Number: ACTRN12619001355167 Start Date*: 2023-06-23
    Sponsor Name:Monash University
    Full Title: 20% Albumin infusion and AKI following cardiac surgery – Randomised Trial
    Medical condition: Acute kidney injury (AKI) is a common complication of cardiac surgery. AKI is defined according to KDIGO criteria in 3 severity stages. KDIGO creatinine-based criteria for diagnosis and staging of...
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004857 10080266 Stage 1 acute kidney injury LLT
    20.1 100000004857 10080269 Stage 2 acute kidney injury LLT
    20.1 100000004857 10080271 Stage 3 acute kidney injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001701-13 Sponsor Protocol Number: FFAKI Start Date*: 2015-09-19
    Sponsor Name:Nordsjællands Hospital. Dept. of Anaesthesiology and Intensive Care.
    Full Title: Forced fluid removal vs. usual care in intensive care patients with high-risk acute kidney injury and severe fluid overload (FFAKI) – A randomized clinical trial
    Medical condition: Fluid overload associated with acute kidney injury in patients admitted to the intensive care unit
    Disease: Version SOC Term Classification Code Term Level
    18.0 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    18.0 10027433 - Metabolism and nutrition disorders 10016803 Fluid overload PT
    18.0 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004223-12 Sponsor Protocol Number: CT-1KIDN-01 Start Date*: 2012-08-27
    Sponsor Name:Digna Biotech S.L.
    Full Title: A pilot, randomised, double blind, placebo-controlled, parallel groups, clinical trial to investigate the efficacy and safety of Cardiotrophin-1 (CT-1) in kidney transplantation.
    Medical condition: Kidney transplantation.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-002594-28 Sponsor Protocol Number: APHP200036 Start Date*: 2022-10-05
    Sponsor Name:ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (AP-HP)
    Full Title: Graft Acute kidney injury: vitamin B3 to facilitate renal Recovery In the Early Life of a transplant
    Medical condition: Patients with end-stage renal failure treated with extrarenal purification (hemodialysis using a catheter or a fistula, or peritoneal dialysis), registered on the national kidney donation waiting l...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003890-23 Sponsor Protocol Number: Cisplatin Start Date*: 2021-02-23
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: The nephroprotective effect of short hydration during cisplatin treatment in head and neck cancer patients.
    Medical condition: Cisplatin induced nephrotoxicity
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-000887-23 Sponsor Protocol Number: CTIN816B12201 Start Date*: 2022-10-03
    Sponsor Name:Novartis Farmacéutica, S.A.
    Full Title: A multicenter, participant and investigator-blinded, randomized, placebo-controlled Phase 2a study to investigate the pharmacokinetics, pharmacodynamics, safety and tolerability of TIN816 in the tr...
    Medical condition: Acute kidney injury Due to sepsis
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Restarted) FR (Completed) DE (Completed) BE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2010-022630-92 Sponsor Protocol Number: AP214-CS007 Start Date*: 2010-11-05
    Sponsor Name:Action Pharma A/S
    Full Title: An Explorative Phase 2, Randomized, Double-Blind, Placebo-Controlled, Safety and Efficacy Trial of two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Su...
    Medical condition: Action Pharma is developing AP214 Acetate for the prevention of postsurgical kidney injury after cardiac surgery. Trial population is patients with increased risk for development of Kidney Inju...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10022117 - Injury, poisoning and procedural complications 10056675 Postoperative renal failure PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-004040-19 Sponsor Protocol Number: 21-ROS-05 Start Date*: 2022-02-09
    Sponsor Name:Guard Therapeutics International AB
    Full Title: A Phase 2, Randomized, Placebo-Controlled, Double-Blind, Adaptive, Parallel Group Clinical Study to Evaluate the Efficacy and Safety of RMC-035 in Subjects at High Risk for Acute Kidney Injury Foll...
    Medical condition: Cardiac surgery associated acute kidney injury
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-002547-29 Sponsor Protocol Number: ATB-203 Start Date*: 2019-11-21
    Sponsor Name:Atox Bio
    Full Title: Phase 2 randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety and efficacy of Reltecimod as compared to placebo in addition to standard of care in patients with ...
    Medical condition: Acute kidney injury due to intra-abdominal infection/sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004857 10080269 Stage 2 acute kidney injury LLT
    20.1 100000004857 10080271 Stage 3 acute kidney injury LLT
    20.1 100000004862 10079983 Complicated intra-abdominal infection LLT
    20.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-001922-24 Sponsor Protocol Number: 120541 Start Date*: 2013-07-12
    Sponsor Name:University College London (UCL)
    Full Title: The effect of remote ischaemic preconditioning and glyceryl trinitrate on peri-operative myocardial injury in cardiac bypass surgery patients (ERIC-GTN study)- a four arm randomised controlled trial
    Medical condition: We are investigating the phenomenon of ischaemic-reperfusion injury. Reperfusion of the ischaemic myocardium is known to cause further myocardial damage. We wish to investigate the phenomenon of Re...
    Disease: Version SOC Term Classification Code Term Level
    16.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-003298-24 Sponsor Protocol Number: EVITAESTEROIDE-12 Start Date*: 2014-06-26
    Sponsor Name:Sociedad Andaluza de Trasplante de Órganos y Tejidos (SATOT)
    Full Title: Steroid withdrawal and novo donor-specific anti-HLA antibodies in renal transplant patients: a prospective, randomized and controlled study in parallel groups.
    Medical condition: Kidney transplantaion
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004865 10023438 Kidney transplant LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000757-49 Sponsor Protocol Number: QRK309 Start Date*: 2018-12-05
    Sponsor Name:Quark Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Placebo Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of QPI-1002 for the Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for A...
    Medical condition: QPI-1002 is being developed for prevention of acute kidney injury (AKI) in patients at risk for AKI following cardiac surgery and for reduction in the incidence and severity of delayed graft functi...
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) GB (GB - no longer in EU/EEA) BE (Completed) CZ (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020452-64 Sponsor Protocol Number: version2.0 Start Date*: 2010-10-05
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust
    Full Title: A prospective randomisd open label study to determine the effects of intravenous iron administration on markers of acute kidney injury in chronic kidney disease (CKD)
    Medical condition: patients with known chonic kidney disease with functional or absolute Iron deficiency Anaemia, and are greater than 18 years will be given repleacement iron therapy accoring to current local protoc...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10005329 - Blood and lymphatic system disorders 10022973 Iron deficiency anaemias LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004871-11 Sponsor Protocol Number: ULA02 Start Date*: 2019-09-05
    Sponsor Name:Cardiorentis AG
    Full Title: RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED DOSE ESCALATION STUDY OF ULARITIDE FOLLOWED BY A 42-HOUR INFUSION FOR THE TREATMENT OF ACUTE KIDNEY INJURY (AKI) IN PATIENTS POST CARDIAC SURGERY
    Medical condition: Acute kidney injury in patients post cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000756-34 Sponsor Protocol Number: 2012.001 Start Date*: 2012-11-02
    Sponsor Name:NeuroVive Pharmaceutical AB
    Full Title: Copenhagen Head Injury Ciclosporin (CHIC) Study: An open-label, uncontrolled Phase II -study to investigate pharmacokinetics, safety and biomarkers of effectiveness of NeuroSTAT® (ciclosporin) i...
    Medical condition: Severe Traumatic Brain Injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-004625-24 Sponsor Protocol Number: AP-recAP-AKI-03-01 Start Date*: 2020-09-04
    Sponsor Name:AM-Pharma B.V.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Two-Arm Parallel Group, Multi-Center Phase 3 Pivotal Trial to Investigate the Efficacy and Safety of Recombinant Human Alkaline Phosphatase for Treat...
    Medical condition: Sepsis-associated acute kidney injury
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    20.0 10021881 - Infections and infestations 10066593 Post procedural sepsis PT
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended) NL (Completed) DK (Prematurely Ended) FI (Completed) DE (Prematurely Ended) GB (GB - no longer in EU/EEA) BE (Completed) IE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001322-54 Sponsor Protocol Number: CS/2018/6632 Start Date*: 2020-06-15
    Sponsor Name:University Hospitals Bristol and Weston NHS Foundation Trust
    Full Title: Carbon Dioxide Insufflation and Brain Protection During Open Heart Surgery: A Randomised Controlled Trial
    Medical condition: Brain injury during open heart valve surgery
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10067967 Brain injury PT
    21.1 100000004865 10048935 Open heart surgery LLT
    20.0 10029205 - Nervous system disorders 10077808 Mild neurocognitive disorder LLT
    20.0 10047065 - Vascular disorders 10001526 Air embolism PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-001604-30 Sponsor Protocol Number: 1001 Start Date*: 2017-12-11
    Sponsor Name:Medical University of Vienna
    Full Title: Safety, Tolerability and Efficacy of anti-IL-6 Antibody Clazakizumab in Late Antibody-Mediated Rejection after Kidney Transplantation - A Pilot Trial
    Medical condition: Antibody-mediated rejection of a kidney transplant
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004555-79 Sponsor Protocol Number: 16-115 Start Date*: 2017-08-08
    Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty
    Full Title: Impact of preoperative midazolam on outcome of elderly patients: a multicenter randomised controlled trial
    Medical condition: Under investigation are elderly patients (≥65 years of age) undergoing each kind of surgery with planned general or combined regional and general anaesthesia. Primary, we will investigate the posto...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-001455-39 Sponsor Protocol Number: OPN-305-102 Start Date*: 2012-10-10
    Sponsor Name:Opsona Therapeutics Ltd
    Full Title: A Three-Part, Multi-Centre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Sequential Adaptive, Phase II Study to Evaluate the Safety, Tolerability and Efficacy of OPN-305, a Humanis...
    Medical condition: Prevention of Kidney Graft Dysfunction
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004863 10051366 Kidney graft dysfunction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) NL (Completed) GB (Completed) CZ (Completed) AT (Completed) ES (Ongoing) PL (Completed)
    Trial results: (No results available)
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