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Clinical trials for Liver Cirrhosis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    537 result(s) found for: Liver Cirrhosis. Displaying page 2 of 27.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2013-002416-27 Sponsor Protocol Number: INFECIR2 Start Date*: 2013-10-23
    Sponsor Name:Fundacio Clinic per a la recerca biomedica
    Full Title: Albumin administration in the prevention of hepatorenal syndrome and death in patients with cirrhosis, bacterial infections other than spontaneous bacterial peritonitis and high risk of hospital mo...
    Medical condition: Patients with advanced cirrhosis (serum creatinine > 1.2 mg/dl, serum sodium < 130 mEq/l and/or serum bilirubin > 4 mg/dl), signs of systemic inflammation and urinary infection, pneumonia, skin/sof...
    Disease: Version SOC Term Classification Code Term Level
    16.0 10019805 - Hepatobiliary disorders 10024667 Liver cirrhosis LLT
    16.0 10019805 - Hepatobiliary disorders 10008954 Chronic liver disease and cirrhosis LLT
    16.0 10019805 - Hepatobiliary disorders 10019641 Hepatic cirrhosis PT
    16.0 10019805 - Hepatobiliary disorders 10064704 Decompensated cirrhosis LLT
    16.0 10019805 - Hepatobiliary disorders 10009213 Cirrhosis of liver LLT
    16.0 10019805 - Hepatobiliary disorders 10009211 Cirrhosis liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) ES (Ongoing) IT (Prematurely Ended) BE (Prematurely Ended) DE (Prematurely Ended) AT (Prematurely Ended) DK (Prematurely Ended) IE (Prematurely Ended) GB (Prematurely Ended) NL (Ongoing)
    Trial results: View results
    EudraCT Number: 2012-002890-71 Sponsor Protocol Number: RifaxNK150612 Start Date*: 2012-08-16
    Sponsor Name:Flemming Bendtsen
    Full Title: Intestinal decontamination with rifaximin. Effects on the inflammatory and circulatory state in patients with cirrhosis and ascites - A randomised controlled clinical study
    Medical condition: Liver cirrhosis of any etilogy, complicated by decompensation and classified as Child-Pugh B or C
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004871 10024667 Liver cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-006393-14 Sponsor Protocol Number: UDT-1/PHT Start Date*: 2007-10-23
    Sponsor Name:Dr. Falk Pharma GmbH
    Full Title: Double-Blind, Randomised, Parallel-Group, Placebo-Controlled, Multi-Centre Phase II Clinical Study on the Efficacy and Safety of Different Doses of Udenafil in Cirrhotic Patients with Portal Hypert...
    Medical condition: Portal hypertension, liver cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10019805 - Hepatobiliary disorders 10036200 Portal hypertension PT
    13.1 10019805 - Hepatobiliary disorders 10024667 Liver cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) LT (Completed) CZ (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-000488-34 Sponsor Protocol Number: PVTRIFA2017 Start Date*: 2017-06-14
    Sponsor Name:UMBERTO I - POLICLINICO DI ROMA
    Full Title: RIFAXIMIN BLUNTED HIGHER LEVELS OF ENDOTOXIN IN CIRRHOSIS PATIENTS: A RANDOMIZED, DOUBLE BLIND, SHORT TERM INTERVENTIONAL TRIAL.
    Medical condition: PATIENTS WITH CIRRHOSIS CHILD PUGH B or C Classes
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10009211 Cirrhosis liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005679-33 Sponsor Protocol Number: KKSH-042 Start Date*: 2011-01-20
    Sponsor Name:Medizinische Fakultät der Martin-Luther-Universität Halle-Wittenberg
    Full Title: Influence of the selective endothelin receptor-blocker Ambrisetan on the portal pressure in patients with cirrhosis
    Medical condition: Portal hypertension and hepatic cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10019805 - Hepatobiliary disorders 10036200 Portal hypertension PT
    16.1 10019805 - Hepatobiliary disorders 10009213 Cirrhosis of liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002940-86 Sponsor Protocol Number: SELLIFA-02 Start Date*: 2007-08-24
    Sponsor Name:Cliniques Universitaires Saint-Luc – Université catholique de Louvain
    Full Title: Sepsis, Endothelial function, and Lipids in critically ill patients with Liver Failure (SELLIFA). Nutritional sub-study : Randomized controlled trial comparing the tolerance on lipid metabolism and...
    Medical condition: Liver failure, Liver cirrhosis, critical illness, total nutritional support
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009211 Cirrhosis liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004809-33 Sponsor Protocol Number: BETA Start Date*: 2015-03-09
    Sponsor Name:Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (VHIR)
    Full Title: Albumin infusion effects in patients with cirrhosis hepatic encephalopathy
    Medical condition: hepatic encephalopathty
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004871 10019642 Hepatic cirrhosis NOS LLT
    17.1 10029205 - Nervous system disorders 10019660 Hepatic encephalopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-024651-86 Sponsor Protocol Number: TEHYLIC Start Date*: 2011-05-30
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Randomized Trial, Masked, and Placebo Controlled to Assess the Effects of Sapropterin on Hepatic and Systemic Hemodynamics in Patients With Liver Cirrhosis and Portal Hypertension
    Medical condition: Cirrosis hepática, Hipertensión portal
    Disease: Version SOC Term Classification Code Term Level
    14.1 10019805 - Hepatobiliary disorders 10020786 Hypertension portal LLT
    14.1 10019805 - Hepatobiliary disorders 10019641 Hepatic cirrhosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003547-36 Sponsor Protocol Number: NRL972-09/2008- (CHBC) Start Date*: 2009-02-12
    Sponsor Name:Norgine Ltd
    Full Title: An open study to investigate the effects of chronic hepatitis B or C on the pharmacokinetics of cholyl-lysyl-fluorescein (NRL972) before, during and after standard treatment
    Medical condition: In-vivo diagnostic marker for liver dysfunction.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009213 Cirrhosis of liver LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2018-002778-35 Sponsor Protocol Number: 87RI18_0008 Start Date*: 2018-11-06
    Sponsor Name:CHU de Limoges
    Full Title: Description of the evolution of plasma and urinary concentrations of iohexol in a cirrhotic patient population. "Pilot study on 9 patients"
    Medical condition: Patients with advanced liver disease, with potential indication for liver transplantation, with or without ascites
    Disease: Version SOC Term Classification Code Term Level
    20.0 10019805 - Hepatobiliary disorders 10019641 Hepatic cirrhosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2013-002409-75 Sponsor Protocol Number: Dota-PrimoLIV Start Date*: 2014-01-06
    Sponsor Name:Charite
    Full Title: Intra-individual, comparison of the MRI contrast agents gadoxetic acid (Primovist®) versus gadoterate meglumine (Dotarem®) in liver MRI of patients with HCC and underlying cirrhosis
    Medical condition: Patients with liver cirrhosis and diagnosis of hepatocellular carcinoma based on noninvasive HCC diagnostic (EASL) criteria
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004871 10024667 Liver cirrhosis LLT
    18.1 100000004864 10049010 Carcinoma hepatocellular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017819-16 Sponsor Protocol Number: OP-GIB Start Date*: 2011-08-22
    Sponsor Name:Juan Cordoba
    Full Title: Efectos de la administración de ornitina-fenilacetato (OCR-002) en pacientes con cirrosis y hemorragia digestiva alta. Effects of the administration of ornithine phenylacetate (OP, OCR-002) in pati...
    Medical condition: Hemorragia digestiva en pacientes con cirrosis hepática
    Disease: Version SOC Term Classification Code Term Level
    13.1 10017947 - Gastrointestinal disorders 10019543 Hemorrhage gastrointestinal LLT
    13.1 10019805 - Hepatobiliary disorders 10019641 Hepatic cirrhosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-002166-20 Sponsor Protocol Number: AMELIORATE Start Date*: 2012-02-08
    Sponsor Name:Fundació Clinic per a la Recerca Biomèdica
    Full Title: Treatment of hepatorenal syndrome with terlipressin infusion adjusted to hemodynamic response
    Medical condition: Hepatorenal syndrome (HRS) type 1
    Disease: Version SOC Term Classification Code Term Level
    14.1 10019805 - Hepatobiliary disorders 10019846 Hepatorenal syndrome PT
    14.1 10019805 - Hepatobiliary disorders 10019641 Hepatic cirrhosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005723-14 Sponsor Protocol Number: MACHT Start Date*: 2008-04-21
    Sponsor Name:Fundació Clinic per a la recerca biomèdica
    Full Title: EFECTO DE LA ADMINISTRACIÓN PROLONGADA DE ALBÚMINA Y MIDODRINA EN LA PREVENCIÓN DE COMPLICACIONES EN PACIENTES EN LISTA DE ESPERA DE TRASPLANTE HEPÁTICO Midodrine and Albumin for CirrHotic patients...
    Medical condition: Pacientes afectos de cirrósis hepática en lista de espera para trasplante Hepático
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019641 Hepatic cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-006577-30 Sponsor Protocol Number: D4326C00003 Start Date*: 2022-09-21
    Sponsor Name:AstraZeneca AB
    Full Title: A Two Part Phase IIa/b Multicentre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Dose-ranging Study to Assess Efficacy, Safety, and Tolerability of the Combination of Zibotentan and...
    Medical condition: Liver cirrhosis with features of portal hypertension.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10024667 Liver cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) AT (Trial now transitioned) DK (Trial now transitioned) BE (Trial now transitioned) NL (Trial now transitioned) DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001222-83 Sponsor Protocol Number: HHSC/001 Start Date*: 2005-12-09
    Sponsor Name:Imperial College London
    Full Title: A phase I/II safety and tolerability dose escalation study following the autologous infusion of expanded adult haemopoietic stem cells to patients with liver insufficiency
    Medical condition: Chronic liver insufficiency
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024667 Liver cirrhosis LLT
    9.1 10024670 Liver disorder LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-010396-25 Sponsor Protocol Number: PREDESCI Start Date*: 2009-05-28
    Sponsor Name:Càndid Villanueva
    Full Title: Estudio multicéntrico, aleatorizado, doble-ciego, controlado con placebo, sobre la eficacia del tratamiento con beta-bloqueantes pra aprevenir la descompenzación de la cirrosis con hipertensión po...
    Medical condition: Cirrosis hepática con hipertensión portal clínicamente significativa (mayor o igual a 10 mm Hg) sin descompensaciones como varíces esofágicas, ascitis, o encefalopatía hepática.
    Disease: Version SOC Term Classification Code Term Level
    9 10019641 Hepatic cirrhosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012592-10 Sponsor Protocol Number: 09-057 Start Date*: 2009-07-23
    Sponsor Name:CHU Caen
    Full Title: Méthode d’évaluation de l’aptitude à la conduite chez des patients souffrant de pathologies de l’éveil: cirrhose avec ou sans encéphalopathie (AutoSoP "foie").
    Medical condition: cirrhose
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019641 Hepatic cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012919-17 Sponsor Protocol Number: P071220 Start Date*: 2009-11-12
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Etude multicentrique randomisée en double insu des effets de l'administration de norfloxacine ou d'un placebo sur la survie des malades atteints de cirrhose avec une insuffisance hépatocellulaire
    Medical condition: Malades atteints de cirrhose avec une insuffisance hépatocellulaire de grade C de Child-Pugh
    Disease: Version SOC Term Classification Code Term Level
    8.1 10019641 Hepatic cirrhosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003629-13 Sponsor Protocol Number: PROFIT Start Date*: 2018-01-31
    Sponsor Name:King's College London [...]
    1. King's College London
    2. King's College Hospital NHS Fundation Trust
    Full Title: A Prospective, randomised placebo controlled feasibility trial of Faecal Microbiotica Transplantation in cirrhosis
    Medical condition: Cirrhosis of the liver
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10024667 Liver cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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