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Clinical trials for Musculoskeletal diseases

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,431 result(s) found for: Musculoskeletal diseases. Displaying page 3 of 72.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-000431-32 Sponsor Protocol Number: ORTHOUNION Start Date*: 2017-05-25
    Sponsor Name:Universidad Autónoma de Madrid (U.A.M.)
    Full Title: A MULTI-CENTRE, OPEN-LABEL, RANDOMIZED, COMPARATIVE CLINICAL TRIAL OF TWO DIFFERENT DOSES OF BONE MARROW AUTOLOGOUS HUMAN MESENCHYMAL STEM CELLS PLUS BIOMATERIAL VERSUS ILIAC CREST AUTOLOGOUS GRAFT...
    Medical condition: Diaphyseal and/or metaphysodiaphyseal fractures (femur, tibia, humerus) with status of non-union
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10017085 Fracture malunion PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing) DE (Completed) FR (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024659-10 Sponsor Protocol Number: 2010-024659-10 Start Date*: 2011-08-03
    Sponsor Name:Rigshospitalet
    Full Title: Can stimulation of the nNOS system in muscle disease with nNOS insufficiency improve heart and skeletal muscle function and cognition?
    Medical condition: Muscular dystrophy with nNOS insufficiency
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10028301 Muscle disorder NOS LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-000571-37 Sponsor Protocol Number: ET21-030 Start Date*: 2021-08-02
    Sponsor Name:Centre Léon Bérard
    Full Title: A multicenter, randomized, open-label phase II trial evaluating the association of Gadolinium-based nanoparticles (AGuIX®) with radiotherapy for the therapeutic management of patients with progress...
    Medical condition: Patients with metastatic renal cancer, melanoma or sarcoma, or with non-metastatic sarcoma (soft tissue, chondrosarcoma, osteosarcoma…), and with a progressive / recurrent inoperable musculoskeleta...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2011-003082-15 Sponsor Protocol Number: KTB-002 Start Date*: 2011-09-08
    Sponsor Name:Karen Toftdahl Bjørnholdt
    Full Title: High dose dexamethasone for pain following arthroscopic shoulder surgery: A randomised blinded clinical trial.
    Medical condition: Pain following arthroscopic shoulder surgery.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10040617 Shoulder pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005285-38 Sponsor Protocol Number: IM101-591 Start Date*: 2020-01-14
    Sponsor Name:The University of Leeds
    Full Title: Phase II proof of concept study of Abatacept (Orencia) in individuals who aRe Considered At risk of Developing Inflammatory Arthritis
    Medical condition: Inflammatory arthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10003246 Arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-004057-25 Sponsor Protocol Number: RC21/18 Start Date*: 2019-10-02
    Sponsor Name:IRCCS MATERNO INFANTILE BURLO GAROFOLO
    Full Title: Oral Ibuprofene versus oral kethorolac for children with musculoskeletal injury: a double blind randomized controlled study.
    Medical condition: Pain is present in 78% of overall accesses in pediatric emergency rooms and, in most cases, it is acute and secondary to musculoskeletal trauma. Fifthy percent of patients report moderate to severe...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10033472 Pain of extremties LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002143-95 Sponsor Protocol Number: M12-141 Start Date*: 2012-10-04
    Sponsor Name:Abbott GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-blind, Placebo- and Active-Controlled Study Comparing the Safety and Analgesic Efficacy of ABT-110 to Placebo in Subjects with Chronic Low Back Pain
    Medical condition: Chronic Low Back Pain
    Disease: Version SOC Term Classification Code Term Level
    15.0 10028395 - Musculoskeletal and connective tissue disorders 10008837 Chronic back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended) PL (Prematurely Ended) IT (Prematurely Ended) FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-018085-35 Sponsor Protocol Number: 4682724 Start Date*: 2010-05-21
    Sponsor Name:Regionalhospital Silkeborg
    Full Title: Intestinal Inflammation in Ankylosing Spondylitis assessed by Fecal Calprotectin, Capsular Endoscopy and Colonoscopy and the effects of Adalimumab on mucosal healing
    Medical condition: Ankylosing spondylitis Inflammatory bowel disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10061371 Spondylitis PT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10041672 Spondylitis ankylosing LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10048398 Spondylitis ankylosing aggravated LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10041671 Spondylitis ankylopoietica LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10002556 Ankylosing spondylitis PT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10041673 Spondylitis NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-015578-37 Sponsor Protocol Number: BAY12-8039/11643 Start Date*: 2010-05-10
    Sponsor Name:Bayer HealthCare AG
    Full Title: A randomized, double-blind, multicenter trial to evaluate the safety and efficacy of sequential (intravenous, oral) moxifloxacin versus comparator in pediatric subjects with complicated intraabdomi...
    Medical condition: Complicated intra-abdominal infections (cIAI)
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10056570 Intra-abdominal infection LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) ES (Prematurely Ended) LV (Completed) LT (Completed) CZ (Completed) BE (Prematurely Ended) HU (Completed) BG (Completed) GR (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-005330-20 Sponsor Protocol Number: WA20495 Start Date*: 2007-06-07
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: A randomized, double-blind, parallel group, international study to evaluate the safety and efficacy of ocrelizumab compared to placebo in patients with active rheumatoid arthritis who have an in...
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) FR (Completed) HU (Completed) ES (Temporarily Halted) CZ (Completed) NL (Completed) SI (Completed) SE (Completed) IT (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2019-004088-34 Sponsor Protocol Number: APHP180571 Start Date*: 2020-02-04
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS ( AP-HP)
    Full Title: Effect of two injections of synchronized methotrexate with the first injection of Adalimumab to prevent anti-adalimumab immunization in spondyloarthritis
    Medical condition: adult patients with Axial Spondyloarthritis who have an indication for anti-TNF therapy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    21.1 10028395 - Musculoskeletal and connective tissue disorders 10071400 Axial spondyloarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002964-15 Sponsor Protocol Number: STH19102 Start Date*: 2016-12-06
    Sponsor Name:Sheffield Teaching Hospitals
    Full Title: The Effect of Selenium Supplementation on Musculoskeletal Health in Older Women Double-blind, randomised, placebo-controlled trial
    Medical condition: Osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10031282 Osteoporosis PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-003148-11 Sponsor Protocol Number: MoA-Ustekinumab Start Date*: 2015-01-29
    Sponsor Name:Academic Medical Center
    Full Title: Mechanism of action study of Ustekinumab treatment in psoriatic arthritis: Impact on cellular and molecular pathways of synovial inflammation and tissue remodeling
    Medical condition: psoriatic arthritis
    Disease: Version SOC Term Classification Code Term Level
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10066579 Progression of psoriatic arthritis LLT
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10066730 Recurrent psoriatic arthritis LLT
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10037160 Psoriatic arthritis LLT
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10003377 Arthropathy psoriatic LLT
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10037161 Psoriatic arthritis aggravated LLT
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10037162 Psoriatic arthropathy PT
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10037163 Psoriatic arthropathies HLT
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10037166 Psoriatic spondylitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002085-31 Sponsor Protocol Number: RAD-ON02 Start Date*: 2017-11-14
    Sponsor Name:Kurort Forschungsverein Bad Steben e.V.
    Full Title: Determining the immunological and pain reducing effects of serial radon balneology in patients with musculoskeletal disorders.
    Medical condition: Chronic degenerative spine and/or joint disorders with pain perception of at least 1 year and pain intensity on visual analogue scale ≥4
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002633-19 Sponsor Protocol Number: RZR12011-TryCort Start Date*: 2011-12-21
    Sponsor Name:Rheumazentrum Ruhrgebiet
    Full Title: Diagnostic value of oral prednisolone test for rheumatoid arthritis
    Medical condition: rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10062719 Seronegative rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002822-22 Sponsor Protocol Number: NL66032.091.18 Start Date*: 2018-09-21
    Sponsor Name:Sint Maartenskliniek
    Full Title: US-guided Percutaneous needle tenotomy in Patients with Lateral Elbow Tendinopathy: A multicenter Randomized Controlled Trial
    Medical condition: Lateral Elbow Tendinopathy is a common cause for chronic pain in the elbow, where the pain is present for longer than 6 months. Currently, the rationale is that the tendinopathy is the result of th...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002096-26 Sponsor Protocol Number: MV-3-2017 Start Date*: 2017-08-24
    Sponsor Name:Universitetsklinik for Nyresygdomme og Blodtryksforhøjelse, Regionshospitalet Holstebro; Hospitalsenheden Vest
    Full Title: Investigate the differences between treating Chronic Kidney Disease - Mineral and Bone Disorder with an iron-containing phosphate binder or a calcium-containing phosphate binder in dialysis patients.
    Medical condition: Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD), especially bone metabolism and blood vessel calcification
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10027425 Metabolic bone disorders HLT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10078095 Chronic kidney disease-mineral and bone disorder PT
    20.0 100000004869 10012347 Dependence on renal dialysis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-004406-25 Sponsor Protocol Number: FCM-RHEUMA-001 Start Date*: 2014-09-19
    Sponsor Name:Faculdade de Ciências Médicas da Universidade Nova de Lisboa
    Full Title: Biomarkers identification of anti-TNF α agent’s efficacy in Ankylosing Spondylitis patients using a transcriptome analysis and mass spectrometry
    Medical condition: Ankylosing Spondylitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10002556 Ankylosing spondylitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003418-28 Sponsor Protocol Number: CLNA043X2201 Start Date*: 2017-04-18
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, placebo-controlled, patient and investigator blinded, single dose, Proof of Concept study investigating the safety, tolerability and preliminary efficacy of intra-articular LNA043 in ...
    Medical condition: Acute cartilage injuries
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003484-38 Sponsor Protocol Number: P120206 Start Date*: 2015-01-22
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10016686 Finger osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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