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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44400   clinical trials with a EudraCT protocol, of which   7411   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,400 result(s) found. Displaying page 5 of 2,220.
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    EudraCT Number: 2016-002112-41 Sponsor Protocol Number: 2016-05-04 Start Date*: 2016-07-16
    Sponsor Name:Region Östergötland
    Full Title: Can Insuline improve the healing of dental implants?
    Medical condition: Missing teeth
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001264-11 Sponsor Protocol Number: UMCM-2016EPI05 Start Date*: 2016-09-07
    Sponsor Name:University Medical Center of the Johannes Gutenberg-University Mainz
    Full Title: A phase IV, single-center, randomized, double-blind, placebo-controlled, parallel group study on the effects of empagliflozin on left ventricular diastolic function compared to usual care in indivi...
    Medical condition: Poorly controlled type 2 diabetes mellitus in adults
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003937-62 Sponsor Protocol Number: CLR_16_23 Start Date*: 2017-03-20
    Sponsor Name:SUN Pharma Global FZE
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multiple Dose, Phase 2b Study to Demonstrate the Safety and Efficacy of Tildrakizumab in Subjects with Active Psoriatic Arthritis
    Medical condition: Psoriatic Arthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000018188 10037160 Psoriatic arthritis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) ES (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2016-005111-40 Sponsor Protocol Number: CN138-178 Start Date*: 2017-04-07
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization, Inc
    Full Title: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Flexible- Dosed Parallel-Group Study of Aripiprazole Flexibly Dosed in the Treatment of Children and Adolescents with Autistic Disorder
    Medical condition: Autistic Disorder
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-000611-17 Sponsor Protocol Number: LTS12745 Start Date*: 2017-08-28
    Sponsor Name:Alfresa Pharma Corporation and Sanofi KK
    Full Title: A Long term study of M071754 - A open-label study in patients with infantile spasms.
    Medical condition: Patients diagnosed with infantile spasms
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10021750 Infantile spasms PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2019-000608-14 Sponsor Protocol Number: 1.0/170119 Start Date*: Information not available in EudraCT
    Sponsor Name:Tartu University Hospital
    Full Title: Prospective validation of individualized Bayesian dose optimization tool DosOpt for Vancomycin treatment in neonates.
    Medical condition: In neonatal population wide inter-and intra-individual variability of pharmacokinetics makes extremely difficult to ensure optimal exposure of vancomycin with standard regimens. On average >50% of ...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: EE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000608-27 Sponsor Protocol Number: ProtokolSB2 Start Date*: 2016-04-05
    Sponsor Name:Aarhus University Hospital
    Full Title: The effect of subsartorial saphenous block on postoperative pain following major ankle and hind foot surgery
    Medical condition: Post-operative pain after four types of major ankle and hind foot surgery: (1) total ankle arthroplasty, (2) ankle arthrodesis, (3) subtalar arthrodesis or (4) triple arthrodesis
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10003396 Arthroplasty NOS LLT
    19.0 100000004865 10016962 Foot arthrodesis LLT
    19.0 100000004865 10002540 Ankle arthrodesis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-003833-24 Sponsor Protocol Number: AGMT_HNO_PN Start Date*: 2016-06-30
    Sponsor Name:AGMT – Arbeitsgemeinschaft medikamentöse Tumortherapie gemeinnützige GmbH
    Full Title: Randomized phase III study: Supplemental parenteral nutrition for patients with locally advanced inoperable tumors of the head and neck, receiving definitive radiotherapy with Cetuximab or Cisplatin
    Medical condition: Locally advanced inoperable tumors of the head and neck under definitive radiotherapy with Cetuximab or Cisplatin
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10031117 Oropharyngeal squamous cell carcinoma stage III LLT
    20.0 100000004864 10041862 Squamous cell carcinoma of the oral cavity stage III LLT
    20.0 100000004864 10041863 Squamous cell carcinoma of the oral cavity stage IV LLT
    20.0 100000004864 10031103 Oropharyngeal cancer stage unspecified LLT
    20.0 100000004864 10041855 Squamous cell carcinoma of the hypopharynx stage IV LLT
    20.0 100000004864 10023860 Laryngeal squamous cell carcinoma stage III LLT
    20.0 100000004864 10041854 Squamous cell carcinoma of the hypopharynx stage III LLT
    20.0 100000004864 10023861 Laryngeal squamous cell carcinoma stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000473-20 Sponsor Protocol Number: CLCZ696B3402 Start Date*: 2016-08-18
    Sponsor Name:Novartis Pharma services AG
    Full Title: A prospective evaluation of natriuretic peptide based referral of CHF patients in primary care
    Medical condition: Chronic heart failure with reduced ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-003629-13 Sponsor Protocol Number: PROFIT Start Date*: 2018-01-31
    Sponsor Name:King's College London [...]
    1. King's College London
    2. King's College Hospital NHS Fundation Trust
    Full Title: A Prospective, randomised placebo controlled feasibility trial of Faecal Microbiotica Transplantation in cirrhosis
    Medical condition: Cirrhosis of the liver
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10024667 Liver cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001974-27 Sponsor Protocol Number: STOPFLU Start Date*: 2019-10-15
    Sponsor Name:Centre Hospitalier Universitaire Vaudois (CHUV)
    Full Title: Reducing the Burden of Influenza after Solid-Organ Transplantation: the STOP-FLU trial [Swiss Trial in solid Organ transplantation on Prevention of inFLUenza]
    Medical condition: Influenza in solid organ transplant patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10022000 Influenza PT
    21.1 10042613 - Surgical and medical procedures 10061890 Organ transplant PT
    21.1 10042613 - Surgical and medical procedures 10059429 Influenza immunisation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002956-18 Sponsor Protocol Number: ZWI-ZW25-202 Start Date*: 2020-03-25
    Sponsor Name:Zymeworks Inc.
    Full Title: Phase 2a Study of ZW25 in Combination with Palbociclib Plus Fulvestrant
    Medical condition: Breast cancer patients including those with locally advanced (unresectable) or metastatic HER2-positive, HR-positive breast cancer.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001586-87 Sponsor Protocol Number: RSLV-132-04 Start Date*: 2016-09-29
    Sponsor Name:Resolve Therapeutics, LLC
    Full Title: A Phase 2, Double Blind, Placebo Controlled Study of RSLV-132 in Subjects with Primary Sjogren’s Syndrome
    Medical condition: Primary Sjogrens Syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-003248-34 Sponsor Protocol Number: IMPAACTP1110 Start Date*: 2016-11-02
    Sponsor Name:NIAID and NICHD
    Full Title: A PHASE I TRIAL TO EVALUATE THE SAFETY AND PHARMACOKINETICS OF RALTEGRAVIR IN HIV-1-EXPOSED NEONATES AT HIGH RISK OF ACQUIRING HIV-1 INFECTION
    Medical condition: New born babies at risk of acquiring HIV from their infected mothers.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10053529 Vertical human immunodeficiency virus transmission LLT
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-000755-97 Sponsor Protocol Number: EPFL-CNBI-2017-01 Start Date*: 2017-03-16
    Sponsor Name:Defitech Chair in Brain-Machine Interface, EPFL
    Full Title: Brain-computer interface and neuromuscular stimulation for rehabilitation following chronic stroke
    Medical condition: I61 - Intracerebral haemorrhage I63 - Cerebral infarction Chronic condition (at least 10 months after occurrence of cerebrovascular accident)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2017-004903-33 Sponsor Protocol Number: IBM4809 Start Date*: 2018-06-18
    Sponsor Name:Orphazyme A/S
    Full Title: Phase 2/3 Study of Arimoclomol in Inclusion Body Myositis (IBM) A Randomized, Double-blind, Placebo-Controlled Trial
    Medical condition: Sporadic Inclusion Body Myositis (sIBM)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10075052 Sporadic inclusion body myositis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-003486-17 Sponsor Protocol Number: 9-VPH-MVIH Start Date*: 2020-02-11
    Sponsor Name:CARMEN HIDALGO TENORIO
    Full Title: Immunogenicity and safety of a 9-valent human papillomavirus vaccine in HIV-positive women
    Medical condition: New infection and lesions of papillomavirus in HIV-infected women
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002296-18 Sponsor Protocol Number: CaTo-ROC Start Date*: 2015-07-30
    Sponsor Name:Vejle Hospital, Department of Oncology
    Full Title: Cabazitaxel in patients with Recurrent Ovarian Cancer after failure of standard therapy- A phase II trial
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10033130 Ovarian cancer NOS LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-000605-20 Sponsor Protocol Number: FFIS/2017/01/SLT Start Date*: 2017-07-26
    Sponsor Name:Fundación para la Formación e Investigación Sanitarias de la Región de Murcia
    Full Title: PERIPHERAL TRANSCUTANEOUS NEUROMODULATION OF THE POST-TIBIAL NERVE (T-PTNS) FOR SOLIFENACIN 10mg. IN THE TREATMENT OF HYPERACTIVE BLADDER SYNDROME: NON-INFERIORITY PHASE IV RANDOMIZED CLINICAL TRIAL
    Medical condition: Overactive Bladder Syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000307-17 Sponsor Protocol Number: 69HCL16_0743 Start Date*: 2018-07-19
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Microcirculatory and Macrocirculatory Effects of Landiolol on Postoperative Atrial Fibrillation: a Randomized Study. MMELPOAF study.
    Medical condition: Postoperative Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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