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Clinical trials for Knee Arthroplasty

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    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    101 result(s) found for: Knee Arthroplasty. Displaying page 5 of 6.
    « Previous 1  2  3  4  5  6  Next»
    EudraCT Number: 2009-015799-92 Sponsor Protocol Number: FER-SURG02-Pilot Start Date*: 2009-12-02
    Sponsor Name:Universitätspital Zürich Anästhesie
    Full Title: Intravenous ferric carboxymaltose (Ferinject®) with or without Erythropoietin for the correction of preoperative anaemia in patients undergoing orthopaedic surgery
    Medical condition: • To evaluate the effect of the administration of ferric carboxymaltose (Ferinject®) with or without erythropoietin vs. no treatment (standard therapy) on the preoperative anaemia status in patient...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000698-30 Sponsor Protocol Number: LK10 Start Date*: 2011-04-18
    Sponsor Name:Henrik Kehlet
    Full Title: Postoperative søvnforstyrrelser efter Zolpidem behandling ved fast-track hofte- eller knæalloplastik
    Medical condition: Postoperative REM sleep reduction after fast-track hip and knee arthroplasty. Comparison of preoperative level and level of REM on first postoperative night. The effect of one administration of Zo...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10036160 Poor sleep LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004285-15 Sponsor Protocol Number: SM2-PJ-11 Start Date*: 2011-09-22
    Sponsor Name:Professor Jørgen Berg Dahl
    Full Title: A comparison of the efficacy of the Adductor-Canal-Blockade vs. the femoral nerve block on muscle strength and mobilization in healthy volunteers: a randomized study
    Medical condition: Healthy volunteers (intended for postoperative pain treatment in patients after total knee arthroplasty)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-002280-18 Sponsor Protocol Number: FIPRA#3 Start Date*: 2017-09-18
    Sponsor Name:Nordsjællands Hospital Hillerød
    Full Title: Catheter-based peripheral regional anaesthesia after orthopaedic surgery: Comparison of low dose, automated periodic infusions with conventional high dose, continuous infusion, and patient-initiat...
    Medical condition: Postoperative pain, after orthopaedic surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10029173 Nerve block PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-002925-39 Sponsor Protocol Number: CMAA868A2201 Start Date*: 2018-02-23
    Sponsor Name:Novartis Farmacéutica, S.A.
    Full Title: A multicenter, randomized, open-label, blinded endpoint evaluation, active-controlled Phase 2 study to compare the efficacy and safety of s.c. MAA868 versus s.c. enoxaparin in adult patients underg...
    Medical condition: venous thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10066899 Venous thromboembolism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) AT (Prematurely Ended) CZ (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002465-18 Sponsor Protocol Number: PROTEDI Start Date*: 2019-12-16
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Efficacy and tolerance of 4 weeks of tedizolid in prosthetic joint infections treated with implant removal
    Medical condition: prosthetic joint infections treated with implant removal.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-004469-11 Sponsor Protocol Number: PP-SA-001 Start Date*: 2022-01-11
    Sponsor Name:PHERECYDES PHARMA
    Full Title: PhagoDAIR I: A Phase I/II Multicenter, Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Phage Therapy in Patients with Hip or Knee Prosthetic Joint Infection due to Staphylococcus ...
    Medical condition: knee or hip prosthetic joint infection (PJI) due to Staphylococcus aureus, with the indication of DAIR and Suppressive Antibiotics Therapy (SAT
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-018182-13 Sponsor Protocol Number: 671975 Start Date*: 2010-04-14
    Sponsor Name:Ainara Aguirre Caballero
    Full Title: Efectividad del magnesio epidural para reducir las necesidades de analgesia postoperatoria
    Medical condition: Reducción del consumo de opiaceos y anestésicos locales por vía epidural tras cirugía de prótesis total de rodilla. Reduction of consumption of epidural opioid and local anesthetic drugs after tota...
    Disease: Version SOC Term Classification Code Term Level
    9 10036237 Post operative analgesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-000663-45 Sponsor Protocol Number: PREVENT-iT-2021.07 Start Date*: 2023-02-01
    Sponsor Name:Hamilton Health Sciences Corporation
    Full Title: Prospective Randomized Evaluation of Emerging Novel Treatments for Infection prophylaxis in Total Joint Replacement (PREVENT-iT): A Pilot Study
    Medical condition: Persistent Draining Wound and Periprosthetic Joint Infection prevention in patients undergoing total joint replacement
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004601-32 Sponsor Protocol Number: SM4-UG-14 Start Date*: 2015-01-07
    Sponsor Name:Gentofte Hospital
    Full Title: The Effect of Local Anesthetic Volume within the Adductor Canal on Quadriceps Function Evaluated by Electromyography: A Randomized, Observer-Masked, Placebo-Controlled Study in Volunteers.
    Medical condition: Healthy volunteers. Results will be used for optimizing the treatment of post-operative pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    17.1 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006699-40 Sponsor Protocol Number: PTR2007 Start Date*: 2008-03-03
    Sponsor Name:Hospital Clínic
    Full Title: Estudio aleatorizado y doble ciego para establecer el momento más apropiado de la administración de la profilaxis antibiótica en la artroplastia total de rodilla cuando se realiza bajo isquemia Ran...
    Medical condition: Prevention of infection after total knee arthroplasty Prevención de la infección tras artroplastia total de rodilla
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048038 Wound infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004986-15 Sponsor Protocol Number: Protocol_AFCN_17022019 Start Date*: 2019-02-18
    Sponsor Name:Aarhus University Hospital
    Full Title: Ultrasound-guided nerve block of the anterior femoral cutaneous nerves in healthy volunteers
    Medical condition: Pain around the surgical incision after total knee arthroplasty (TKA). The area anesthetized by a combination of nerve block techniques anesthetizing the anterior femoral cutaneous nerves are inve...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10036236 Postoperative pain relief LLT
    20.0 100000004865 10002325 Anesthesia local LLT
    20.1 10022891 - Investigations 10045434 Ultrasound scan PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-003688-30 Sponsor Protocol Number: CS I-040101/02 Start Date*: 2007-02-27
    Sponsor Name:Kuros Biosurgery AG
    Full Title: A phase 2 randomized, controlled, open-label (dose-blinded), multi-center, dose-finding study of the safety and efficacy of I-0401 in the treatment of patients with fractures of the tibial plateau ...
    Medical condition: Fractures of the tibial plateau requiring grafting
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10024956 Lower limb fractures HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) IT (Completed) FR (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002955-40 Sponsor Protocol Number: 69HCL20_0111 Start Date*: 2020-08-12
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Postoperative analgesic effect of orally administrated nefopam after a total knee arthroplasty: a randomized controlled trial
    Medical condition: Major patients who have a surgery in the orthopedic surgery department of the Croix Rousse hospital for a total knee replacement.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2023-000172-36 Sponsor Protocol Number: CHUB-Methadone Start Date*: 2023-02-28
    Sponsor Name:CHU Brugmann
    Full Title: Intraoperative methadone for the prevention of postoperative pain: a randomized, double-blind clinical study in orthopedic surgery.
    Medical condition: Orthopedic surgery
    Disease: Version SOC Term Classification Code Term Level
    23.1 10042613 - Surgical and medical procedures 10051079 Orthopedic procedure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-003078-41 Sponsor Protocol Number: MUC-2/16 Start Date*: 2018-11-23
    Sponsor Name:MUCOS Pharma CZ s.r.o.
    Full Title: Reduction of post-traumatic systemic inflammatory response by Phlogenzym® using total hip replacement as a model.
    Medical condition: Total hip replacement
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-005115-26 Sponsor Protocol Number: SKY0402-C-208 Start Date*: 2008-01-21
    Sponsor Name:Pacira Pharmaceuticals Inc.
    Full Title: A Multicenter, Randomized, Double-Blind, Parallel-Group, Active-Control, Dose-Ranging Study to Evaluate the Safety, Efficacy, and Comparative Systemic Bioavailability of a Single Administration of ...
    Medical condition: post-operative pain management
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) AT (Prematurely Ended) DE (Completed) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-004942-12 Sponsor Protocol Number: Protokol_MFCN_10102020 Start Date*: 2020-11-19
    Sponsor Name:Aarhus University Hospital
    Full Title: Selective ultrasound-guided nerve block of the medial femoral cutaneous nerve in healthy volunteers
    Medical condition: Pain around the surgical incisions after total knee arthroplasty (TKA). The area anesthetized by new nerve block techniques anesthetizing the medial femoral cutaneous nerve are investigated in heal...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    21.0 100000004865 10002325 Anesthesia local LLT
    20.1 10022891 - Investigations 10045434 Ultrasound scan PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-002670-36 Sponsor Protocol Number: OXN3503 Start Date*: 2009-01-30
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A randomised, double-blind, double-dummy, parallel-group multicentre study to demonstrate non-inferiority in pain and locomotor function and improvement in symptoms of constipation in subjects with...
    Medical condition: Pain, locomotor function and improvement in constipation in osteoarthritis patients taking opioids
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    9.1 10021175 Iatrogenic constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) HU (Completed) NL (Completed) ES (Completed) AT (Completed) FI (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-018173-31 Sponsor Protocol Number: POISE-2 Start Date*: 2011-02-25
    Sponsor Name:Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
    Full Title: Ensayo clínico factorial de clonidina y aspirina en pacientes que van a ser sometidos a cirugía no cardiaca y que estén en riesgo moderado o alto de sufrir eventos cardíacos perioperatorios (Estudi...
    Medical condition: Prevención de episodios cardiovasculares en pacientes de moderado a alto riesgo cardiovascular que son sometidos a una cirugía no cardiaca.
    Disease: Version SOC Term Classification Code Term Level
    9 10007649 Cardiovascular disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) AT (Completed) BE (Completed) DK (Completed) GB (Completed) DE (Ongoing)
    Trial results: (No results available)
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