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Clinical trials for Type 2 Diabetes AND Diabetes Mellitus, Type 1 AND Diabetes

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    1,634 result(s) found for: Type 2 Diabetes AND Diabetes Mellitus, Type 1 AND Diabetes. Displaying page 53 of 82.
    EudraCT Number: 2004-002701-68 Sponsor Protocol Number: PSN9301CS01 Start Date*: 2004-12-13
    Sponsor Name:Prosidion Ltd.
    Full Title: A randomised, double-blind, placebo-controlled, multiple dose, time-lagged parallel groups trial, investigating the pharmacodynamics, the safety and tolerability and the pharmacokinetics of PSN9301...
    Medical condition: Diabetes mellitus type 2
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002580-34 Sponsor Protocol Number: THR-1442-C-448 Start Date*: 2016-09-06
    Sponsor Name:Theracos Sub, LLC
    Full Title: A double blind placebo controlled study to evaluate the effect of bexagliflozin tablets on hemoglobin A1c in patients with type 2 diabetes mellitus and moderate renal impairment
    Medical condition: Diabetes Mellitus Type 2 with renal imparement
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004857 10045250 Type II diabetes mellitus with renal manifestations LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-019774-33 Sponsor Protocol Number: CeTMMoTa/ICPDI/2010 Start Date*: 2011-07-26
    Sponsor Name:Fundación progreso y Salud [...]
    1. Fundación progreso y Salud
    2. fundacion progreso y salud
    Full Title: Clinical trial phase I/II multicentric, open, randomized and controlled for the study of stem cells as therapy critical ischemia in low limbs in insulinized type 2 diabetic patients: study of the i...
    Medical condition: Insulinized diabetic patients Pwith chronic critical ischemia in lower limbs
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10012637 Diabetes with peripheral circulatory disorders LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005047-28 Sponsor Protocol Number: CS0011-A-U301 Start Date*: 2007-03-23
    Sponsor Name:DAIICHI SANKYO PHARMA DEVELOPMENT
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO AND ACTIVE COMPARATOR-CONTROLLED, PARALLEL-GROUP STUDY OF THE EFFICACY AND SAFETY OF RIVOGLITAZONE AS MONOTHERAPY TREATMENT OF TYPE 2 DIABETES MELLITUS
    Medical condition: The current study will support an indication for rivoglitazone as oral monotherapy to improve glycemic control in subjects with type 2 diabetes mellitus not adequately controlled with diet and exer...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063624 Type II diabetes mellitus inadequate control LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) LV (Completed) SK (Completed) AT (Completed) CZ (Completed) GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2022-000800-37 Sponsor Protocol Number: 421496 Start Date*: 2022-09-06
    Sponsor Name:St. Olav's University Hospital
    Full Title: An open, controlled investigation of the effect of micro-doses of glucagon on the performance of continuous glucose monitoring in patients with diabetes mellitus type 1.
    Medical condition: Diabetes mellitus type 1
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-004527-32 Sponsor Protocol Number: SITADS Start Date*: 2016-11-22
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Kings College Hospital NHS Foundation Trust
    Full Title: Pilot randomised controlled trial of SITAgliptin for Depressive Symptoms in type 2 diabetes
    Medical condition: Depression in type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10012378 Depression PT
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-001661-27 Sponsor Protocol Number: ISSBRIL0162 Start Date*: 2014-12-12
    Sponsor Name:Sociedad Española de Cardiología
    Full Title: Comparison of TIcagrelor and clopidogrel in patients with Coronary artery diseaSe and type 2 Diabetes Mellitus (TICS-DM): a randomized pharmacodynamic study
    Medical condition: Coronary artery disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-002590-22 Sponsor Protocol Number: NN9924-4338 Start Date*: 2019-07-25
    Sponsor Name:Novo Nordisk A/S
    Full Title: China multi-regional clinical trial: Efficacy and safety of oral semaglutide versus placebo in subjects with type 2 diabetes mellitus treated with diet and exercise only
    Medical condition: Diabetes Mellitus, Type 2
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2017-002756-91 Sponsor Protocol Number: LPS14947 Start Date*: 2019-10-24
    Sponsor Name:Sanofi Aventis Groupe
    Full Title: A 12-week randomized, controlled trial to compare TOUJEO® and TRESIBA® in terms of glucose values in target range and variability during continuous glucose monitoring in patients with type 1 diabet...
    Medical condition: Type 1 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    21.1 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GB (GB - no longer in EU/EEA) NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-000223-17 Sponsor Protocol Number: P07.xxx Start Date*: 2008-02-26
    Sponsor Name:M.S. Arbous
    Full Title: PRACDICAL Study Prevention and Risk factors of Arterial Complications in DIabetics after non-CArdiac surgicaL interventions
    Medical condition: Diabetes Mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000592-17 Sponsor Protocol Number: MODY-TREAT Start Date*: 2012-08-03
    Sponsor Name:Signe H. Østoft, Diabetes Research Division
    Full Title: The effects of GLP-1 in Maturity- onset diabetes of the young (MODY)
    Medical condition: 'Maturity onset diabetes of the young', also called 'Hepatocyte nuclear factor 1-alfa daiabetes'. It is a monogenic form of inherited diabetes.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10026948 Maturity-onset diabetes of the young LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-002685-70 Sponsor Protocol Number: 300A Start Date*: 2015-08-03
    Sponsor Name:Lund University
    Full Title: The Effect of Sitagliptin on Glucagon Dynamics and Incretin Hormones During Mild Hypoglycemia in Elderly Patients with Metformin-Treated Type 2 Diabetes
    Medical condition: Type 2 Diabetes Mellitus
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000006-23 Sponsor Protocol Number: CV181039 Start Date*: 2007-02-12
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Multicenter, Randomized, Double-Blind, Active-Controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of Saxagliptin in Combination with Metformin IR as Initial Therapy Compared to Saxaglip...
    Medical condition: Type 2 Diabetes Mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003745-16 Sponsor Protocol Number: 3639a Start Date*: 2008-10-28
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Trust
    Full Title: Assessment of platelet-dependent thrombosis by an ex vivo arterial injury model: a placebo controlled trial of Clopidogrel as antiplatelet therapy in patients with type 2 diabetes mellitus and coro...
    Medical condition: Type 2 Diabetes Mellitus and Coronary Artery Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-011907-22 Sponsor Protocol Number: ED09/8912 Start Date*: 2010-02-10
    Sponsor Name:University of Leeds
    Full Title: Antiplatelet treatment in patients with diabetes mellitus: is there a difference between aspirin, clopidogrel and prasugrel
    Medical condition: Type 2 diabetes mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-000214-30 Sponsor Protocol Number: P000805 Start Date*: 2017-08-18
    Sponsor Name:Universitätsklinikum Freiburg
    Full Title: Empagliflozin and its effect on heart failure in type 2 diabetes
    Medical condition: Heart failure and type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    21.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005402-11 Sponsor Protocol Number: GLIDE Start Date*: 2016-07-08
    Sponsor Name:Guys and St Thomas NHS Foundation Trust
    Full Title: The Impact of the Combination of the GLP-1 Analogue Liraglutide (Victoza®) and Laparoscopic Adjustable Gastric Banding (LAGB) on Diabetes Control
    Medical condition: Type 2 Diabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-000804-24 Sponsor Protocol Number: D1690C00024 Start Date*: 2015-07-06
    Sponsor Name: AstraZeneca AB
    Full Title: A Multicenter, Double-Blind, Placebo-Controlled, Parallel Group, Randomized, Phase III study to Evaluate the Glycemic Efficacy and Renal Safety of dapagliflozin in patients with Type 2 Diabetes Mel...
    Medical condition: Type 2 Diabetes Mellitus with Moderate Renal Impairment (CKD 3A)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) IT (Completed) ES (Completed) CZ (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2010-024256-28 Sponsor Protocol Number: 28431754DIA2003 Start Date*: 2011-05-25
    Sponsor Name:Janssen Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, 3-Arm, Parallel-Group, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Canagliflozin in the Treatment of Subjects With Type 2...
    Medical condition: Subjects with T2DM with inadequate glycemic control on a maximally effective dose of metformin in monotherapy
    Disease: Version SOC Term Classification Code Term Level
    13.1 10027433 - Metabolism and nutrition disorders 10063624 Type II diabetes mellitus inadequate control LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2017-000922-37 Sponsor Protocol Number: InflamEX Start Date*: 2017-06-09
    Sponsor Name:Medical University of Graz
    Full Title: Effects of continuous exercise on time spent in euglycemia and inflammation under the treatment of insulin degludec in patients with type 1 diabetes – a crossover, randomized trial (InflamEx)
    Medical condition: Diabetes mellitus Type 1
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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