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Clinical trials for Intervention

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    3,168 result(s) found for: Intervention. Displaying page 66 of 159.
    EudraCT Number: 2021-006512-87 Sponsor Protocol Number: PHERFLOT Start Date*: 2022-09-26
    Sponsor Name:Frankfurter Institut für Klinische Krebsforschung IKF GmbH
    Full Title: Pembrolizumab and trastuzumab in combination with FLOT in the perioperative treatment of HER2-positive, localized esophagogastric adenocarcinoma - A phase II trial of the AIO study group – PHERFLOT –
    Medical condition: HER2 positive, localized esophagogastric adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062878 Gastrooesophageal cancer PT
    23.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10066896 HER2 positive gastric cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-002844-25 Sponsor Protocol Number: SM1-JOAST-2019 Start Date*: 2019-11-26
    Sponsor Name:Daniel Hägi-Pedersen
    Full Title: Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty. The RECIPE Randomized Clinical Trial
    Medical condition: Acute postoperative pain after hip arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10054711 Postoperative pain LLT
    20.0 10042613 - Surgical and medical procedures 10020096 Hip arthroplasty PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2022-002571-11 Sponsor Protocol Number: ENHANCE Start Date*: 2022-11-25
    Sponsor Name:Institut Mutualiste Montsouris
    Full Title: EvaluatioN of High-Intensity Focused Ultrasound (HIFU) Hemi-ablation and short-term AndrogeN deprivation therapy Combination to Enhance prostate control for intermediate risk localized prostate can...
    Medical condition: Intermediate risk localized prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10036946 Prostatic cancer LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-005533-20 Sponsor Protocol Number: VOLATILE10600 Start Date*: 2014-12-11
    Sponsor Name:OSPEDALE SAN RAFFAELE IRCCS
    Full Title: VOLATILE ANESTHETICS TO REDUCE MORTALITY IN CARDIAC SURGERY. A MULTICENTRE RANDOMIZED CONTROLLER STUDY
    Medical condition: PATIENTS UNDERGOING CORONARY ARTERY BYOASS GRAFT SURGERY
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003570-26 Sponsor Protocol Number: CLN-PRO-V011 Start Date*: 2019-09-07
    Sponsor Name:Humacyte, Inc.
    Full Title: A Phase 2 Assessment of Humacyte’s Human Acellular Vessel in Patients Needing Vascular Access for Dialysis
    Medical condition: End-stage renal disease (ESRD) requiring placement of an arteriovenous (AV) graft in the arm (upper- or forearm) for dialysis access.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    21.1 10042613 - Surgical and medical procedures 10066772 Vascular access operation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-002000-39 Sponsor Protocol Number: 212602 Start Date*: 2020-09-29
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: B-Fine: An open label, single arm study to mechanistically interrogate the therapeutic effect of GSK3228836 in patients with Chronic Hepatitis B via intrahepatic immunophenotyping
    Medical condition: Chronic Hepatitis B
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10008910 Chronic hepatitis B PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2016-004358-14 Sponsor Protocol Number: BVDStudy Start Date*: 2017-01-18
    Sponsor Name:AZIENDA OSPEDALIERA ARCISPEDALE SANTA MARIA NUOVA/IRCCS DI REGGIO EMILIA
    Full Title: Bromfenac 0.09% versus dexamethasone 0.1% ophthalmic solutions to reduce inflammation after cataract surgery: the BVD Study.
    Medical condition: Postoperative ocular inflammation after cataract surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10015943 Eye inflammation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001365-32 Sponsor Protocol Number: 19CX5006 Start Date*: 2019-07-25
    Sponsor Name:Imperial Joint Research Compliance Office
    Full Title: IP4- CHRONOS: Comparative Health Research Outcomes of NOvel Surgery in Prostate Cancer
    Medical condition: Prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10001186 Adenocarcinoma of prostate LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2020-005130-15 Sponsor Protocol Number: 2019/ABM/01/00009 Start Date*: 2021-09-30
    Sponsor Name:Nicolaus Copernicus University in Torun
    Full Title: Evaluation of safety and efficacy of two ticagrelor-based de-escalation antiplatelet strategies in acute coronary syndrome: the randomized, multicentre, double-blind ELECTRA RCT study.
    Medical condition: Acute Coronary Syndrom (ACS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-004155-13 Sponsor Protocol Number: BMS_IM101-931 Start Date*: 2023-04-20
    Sponsor Name:Universitätsklinikum Freiburg
    Full Title: Study to investigate the restoring of an immunological balance during therapy with abatacept Abatacept restores immune system equilibrium (ARISE)
    Medical condition: CVID patients confirmed according to ESID/PAGID criteria or related disorders which fulfill the diagnostic criteria for CVID and interstitial lung disease or granuloma diagnosed by chest CT positiv...
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021428 - Immune system disorders 10021449 Immunodeficiency common variable PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004482-88 Sponsor Protocol Number: FAR-DOL-2015 Start Date*: 2016-04-25
    Sponsor Name:Fundació Parc Taulí
    Full Title: Randomized clinical trial to compare the safety and effectiveness of metamizol, ibuprofen and tramadol added to a fixed dose of paracetamol in the treatment of post- surgical pain in patients ? 80 ...
    Medical condition: The medical condition being studied is post surgical pain following surgery for femur fracture in patients ? 80 years old
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000573-80 Sponsor Protocol Number: APHP201075 Start Date*: 2021-05-10
    Sponsor Name:APHP DRCI
    Full Title: Acute Myocardial infarction Upbound to percutaneous coronary intervention, immediately (STEMI) or in the Next three Days (NSTEMI), and randomized to Subcutaneous Evolocumab or Normal strategies to ...
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) DE (Trial now transitioned) IT (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002839-66 Sponsor Protocol Number: IMVT-1401-3203 Start Date*: 2023-09-07
    Sponsor Name:Immunovant Sciences, GmbH
    Full Title: An Open-label Extension Study for Participants who Completed Study IMVT-1401-3201 or Study IMVT-1401-3202 to Assess the Efficacy and Safety of Batoclimab for the Treatment of Thyroid Eye Disease (TED)
    Medical condition: Thyroid Eye Disease (TED)
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004853 10084358 Thyroid eye disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Not Authorised) LV (Trial now transitioned) BE (Trial now transitioned) HU (Trial now transitioned) SK (Trial now transitioned) IT (Trial now transitioned) ES (Ongoing) PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-002015-22 Sponsor Protocol Number: Strindfors2 Start Date*: 2022-08-12
    Sponsor Name:Dept. of Obstetrics and Gynecology, Sodersjukhuset
    Full Title: A pilot study and randomized placebo-controlled trial on the effect and timing of oral Tranexamic acid (TA) administered prepartum on postpartum haemorrhage after vaginal delivery
    Medical condition: Postpartum hemorrhage which is defined as bleeding during and after delivery that exceeds 500 ml. It is most commonly due to an atony of the uterus but may also have other causes such as tissue dam...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004868 10071867 Postpartum bleeding LLT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002453-25 Sponsor Protocol Number: MERCURI-2 Start Date*: 2023-03-07
    Sponsor Name:Amsterdam UMC
    Full Title: Preoperative sodium glucose cotransporter 2 inhibitors for prevention of postoperative acute kidney injury in cardiac surgery patients – a randomized, placebo-controlled, multi-centre, phase IV cli...
    Medical condition: Cardiac Surgery-Associated Acute Kidney Injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004857 10080266 Stage 1 acute kidney injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-005001-26 Sponsor Protocol Number: 20-773/M Start Date*: 2021-12-24
    Sponsor Name:UMC Utrecht
    Full Title: Influencing Progression of Airway Disease in Primary Antibody Deficiency
    Medical condition: Primary antibody deficiency: - Unclassified antibody deficiency (unPAD) - IgA deficiency - Specific polysaccharide antibody deficiency (SPAD) - IgG subclass deficiency (IgSD) - Common variable immu...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-002466-13 Sponsor Protocol Number: NICITA Start Date*: 2019-10-23
    Sponsor Name: Institut für Klinische Krebsforschung IKF GmbH
    Full Title: Nivolumab with chemotherapy in pleural mesothelioma after surgery
    Medical condition: Malignant Pleural Mesothelioma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059518 Pleural mesothelioma malignant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001560-19 Sponsor Protocol Number: CSCC-ASC2 Start Date*: 2015-06-29
    Sponsor Name:Department of Cardiology, Rigshospitalet
    Full Title: Allogeneic adipose tissue-derived stromal/stem cell therapy in patients with ischemic heart disease and heart failure
    Medical condition: Ischemic heart disease and heart failure
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-000608-40 Sponsor Protocol Number: No-DAPT-TAVI Start Date*: 2018-07-06
    Sponsor Name:AOU DI BOLOGNA POLICLINICO S.ORSOLA-MALPIGHI
    Full Title: Aspirin versus Aspirin plus Clopidogrel in Patients Undergoing Transcatheter Aortic Valve Replacement: a Randomized Multicenter Study
    Medical condition: valvular aortic stenosis submitted to TAVI
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-003700-31 Sponsor Protocol Number: ImNuT Start Date*: 2017-10-11
    Sponsor Name:Oslo University Hospital
    Full Title: Effects of nutrition therapy on growth, metabolism and inflammation in immature infants; a double-blind randomized, controlled trial
    Medical condition: To determine whether early and prolonged supply of ARA and DHA improves quality of growth and clinical outcomes in extreme premature infants as compared to our present nutrient supply. By closely a...
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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