- Trials with a EudraCT protocol (212)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (2)
212 result(s) found for: Allele.
Displaying page 1 of 11.
EudraCT Number: 2021-005473-10 | Sponsor Protocol Number: BEYOND | Start Date*: 2021-11-24 | |||||||||||
Sponsor Name:Hellenic Institute for the Study of Sepsis | |||||||||||||
Full Title: BEZLOTOXUMAB YIELDED OUTCOMES BY ADDRESSING PERSONALIZED NEEDS IN CLOSTRIDIOIDES DIFFICILE INFECTION: THE BEYOND DOUBLE-BLIND RANDOMIZED CLINICAL TRIAL | |||||||||||||
Medical condition: Clostridioides difficile Infection (CDI) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GR (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2022-001629-65 | Sponsor Protocol Number: D7830C00004 | Start Date*: 2023-03-13 | |||||||||||
Sponsor Name:ASTRAZENECA AB | |||||||||||||
Full Title: A Randomised, Double-blind, Placebo-Controlled, Multi-Center Phase 2b Study to Evaluate the Efficacy, Safety and Tolerability of AZD2693 in Participants with Non-Cirrhotic Non-Alcoholic Steatohepat... | |||||||||||||
Medical condition: Non-cirrhotic non-alcoholic steatohepatitis with fibrosis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2009-017148-15 | Sponsor Protocol Number: CCOX189A2483 | Start Date*: 2010-04-12 |
Sponsor Name:NOVARTIS FARMA | ||
Full Title: A retrospective pharmacogenetic analysis of patients with elevated liver enzymes (Hy s law cases or AST/ALT > 10x ULN) in clinical studies CCOX189A0117, CCOX189A2332, CCOX189A2369, CCOX189A0126,... | ||
Medical condition: patients with elevated liver enzymes (Hy s law cases or AST/ALT > 10x ULN | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: IT (Completed) | ||
Trial results: View results |
EudraCT Number: 2015-005497-38 | Sponsor Protocol Number: RG_15-234 | Start Date*: 2016-05-25 | |||||||||||
Sponsor Name:University of Birmingham | |||||||||||||
Full Title: Effects of TAMoxifen on the Mutant Allele Burden and Disease Course in Patients with MyeloprolifeRatIve Neoplasms | |||||||||||||
Medical condition: Myeloproliferative Neoplasms | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2008-007416-15 | Sponsor Protocol Number: VX08-770-102 | Start Date*: 2009-08-11 | |||||||||||
Sponsor Name:Vertex Pharmaceuticals Incorporated | |||||||||||||
Full Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of VX 770 in Subjects with Cystic Fibrosis and the G551D Mutation | |||||||||||||
Medical condition: Cystic Fibrosis | |||||||||||||
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Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IE (Completed) GB (Completed) DE (Completed) CZ (Completed) FR (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-000672-28 | Sponsor Protocol Number: VX10-770-107 | Start Date*: 2017-03-27 | |||||||||||
Sponsor Name:Vertex Pharmaceuticals Incorporated | |||||||||||||
Full Title: A Phase 2, Single-Blind, Placebo-Controlled Study to Evaluate the Effect of VX-770 on Hyperpolarized Helium-3 Magnetic Resonance Imaging in Subjects With Cystic Fibrosis, the G551D Mutation, and FE... | |||||||||||||
Medical condition: cystic fibrosis | |||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: Outside EU/EEA | |||||||||||||
Trial results: View results |
EudraCT Number: 2022-003009-31 | Sponsor Protocol Number: HH007 | Start Date*: 2022-12-23 | |||||||||||
Sponsor Name:Zealand University Hospital, dept. of Haematology | |||||||||||||
Full Title: Atorvastatin for patients with Philadelphia-negative chronic myeloproliferative neoplasms - Essential thrombocythemia, polycythemia vera and prefibrotic myelofibrosis | |||||||||||||
Medical condition: Essential thrombocythemia, Polycythemia vera, prefibrotic myelofibrosis | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-001638-33 | Sponsor Protocol Number: IKEM-CEM-01 | Start Date*: 2012-10-10 | |||||||||||
Sponsor Name:Institute for Clinical and Experimental Medicine | |||||||||||||
Full Title: Cholesterol 7alpha-hydroxylase polymorphism as a predictor cholesterolemia responsiveness | |||||||||||||
Medical condition: hypercholesterolemia | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: CZ (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2008-007479-26 | Sponsor Protocol Number: VX08-770-103 | Start Date*: 2009-08-11 | |||||||||||
Sponsor Name:Vertex Pharmaceuticals Incorporated | |||||||||||||
Full Title: A Phase 3, 2 Part, Randomized, Double-Blind, Placebo Controlled, Parallel Group Study to Evaluate the Pharmacokinetics, Efficacy and Safety of VX 770 in Subjects Aged 6 to 11 Years with Cystic Fibr... | |||||||||||||
Medical condition: Cystic Fibrosis | |||||||||||||
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Population Age: Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: IE (Completed) GB (Completed) DE (Completed) FR (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2010-020546-96 | Sponsor Protocol Number: VX10-770-106 | Start Date*: 2010-10-08 | |||||||||||
Sponsor Name:Vertex Pharmaceuticals Incorporated | |||||||||||||
Full Title: A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Effect of VX-770 on Lung Clearance Index in Subjects with Cystic Fibrosis, the G551D Mutation, and FEV1 >90%... | |||||||||||||
Medical condition: Cystic Fibrosis | |||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-002431-30 | Sponsor Protocol Number: GT005-03 | Start Date*: 2020-10-21 | |||||||||||
Sponsor Name:Gyroscope Therapeutics | |||||||||||||
Full Title: HORIZON: A Phase II, open-label, outcomes-assessor masked, multicentre, randomised,controlled study to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal inj... | |||||||||||||
Medical condition: Age-related Macular Degeneration (AMD) presents as a progressive loss of vision in the centre of the retina (the macula) resulting in a blurred area or blank spot in the centre of vision. The prima... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) DE (Prematurely Ended) FR (Completed) IE (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2009-015176-10 | Sponsor Protocol Number: BRD 09/6-C | Start Date*: 2010-01-06 |
Sponsor Name:CHU de Nantes | ||
Full Title: CLOFARABINE/ARA-C TREATMENT COMBINED WITH REDUCED-INTENSITY CONDITIONING ALLOGENEIC STEM CELL TRANSPLANTATION FOR ACUTEMYELOID LEUKEMIA IN PRIMARY TREATMENT FAILURE | ||
Medical condition: To improve the 2 year overall survival in patients with acute myeloid leukaemia (AML) in primary treatment failure | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: FR (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2011-003821-93 | Sponsor Protocol Number: VX11-661-101 | Start Date*: 2013-03-13 | |||||||||||
Sponsor Name:Vertex Pharmaceuticals Incorporated | |||||||||||||
Full Title: A Phase 2, Multicenter, Double Blinded, Placebo Controlled Study to Evaluate Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of VX-661 Monotherapy and VX-661/Ivacaftor Cotherapy in Subject... | |||||||||||||
Medical condition: Cystic Fibrosis | |||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2011-005226-21 | Sponsor Protocol Number: ARD12181 | Start Date*: 2012-03-12 | |||||||||||
Sponsor Name:Sanofi-aventis Recherche & Développement | |||||||||||||
Full Title: A Phase II, Multicenter, Open Label, Single Arm Study of SAR302503 in Subjects Previously Treated with Ruxolitinib and with a Current Diagnosis of Intermediate-2 or High-Risk Primary Myelofibrosis,... | |||||||||||||
Medical condition: Hematopoietic neoplasm | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) NL (Prematurely Ended) AT (Completed) ES (Prematurely Ended) DE (Completed) IT (Completed) BE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2007-002657-23 | Sponsor Protocol Number: VX06-770-101 | Start Date*: 2007-10-01 | |||||||||||
Sponsor Name:Vertex Pharmaceuticals Incorporated | |||||||||||||
Full Title: A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study of VX-770 to Evaluate Safety, Pharmacokinetics, and Biomarkers of CFTR Activity in Cystic Fibrosis (CF) Subjects with Genotype G551D | |||||||||||||
Medical condition: cystic fibrosis | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2014-004838-25 | Sponsor Protocol Number: VX14-661-109 | Start Date*: 2015-05-20 | |||||||||||
Sponsor Name:Vertex Pharmaceuticals Incorporated | |||||||||||||
Full Title: A Phase 3, Randomized, Double-Blind, Ivacaftor-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With ... | |||||||||||||
Medical condition: Cystic Fibrosis | |||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) IE (Completed) BE (Completed) AT (Completed) DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2018-000588-99 | Sponsor Protocol Number: BLU-285-2203 | Start Date*: 2019-03-15 | ||||||||||||||||
Sponsor Name:Blueprint Medicines Corporation | ||||||||||||||||||
Full Title: A 3-Part, Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate Safety and Efficacy of Avapritinib (BLU-285), a Selective KIT Mutation-Targeted Tyrosine Kinase Inhibitor, in Indole... | ||||||||||||||||||
Medical condition: Indolent Systemic Mastocytosis (ISM) | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) BE (Ongoing) DE (Ongoing) ES (Ongoing) NL (Ongoing) DK (Ongoing) IT (Ongoing) SE (Ongoing) FR (Ongoing) NO (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2020-005173-28 | Sponsor Protocol Number: BLU-263-1201 | Start Date*: 2021-09-06 | |||||||||||
Sponsor Name:Blueprint Medicines Corporation | |||||||||||||
Full Title: A Randomized, Double-Blind, Placebo-Controlled Phase 2/3 Study of BLU-263 in Indolent Systemic Mastocytosis | |||||||||||||
Medical condition: Indolent Systemic Mastocytosis (ISM) and monoclonal Mast Cell Activation Syndrome (mMCAS) | |||||||||||||
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Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: BE (Ongoing) DE (Ongoing) FR (Ongoing) ES (Ongoing) AT (Ongoing) NL (Ongoing) PT (Ongoing) IT (Ongoing) DK (Ongoing) SE (Ongoing) NO (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-004576-22 | Sponsor Protocol Number: IRI28 | Start Date*: 2017-07-14 |
Sponsor Name:Catharina Hospital Eindhoven | ||
Full Title: SAFETY, FEASIBILITY AND COST-ANALYSIS OF UGT1A1 GENOTYPE-GUIDED DOSING OF IRINOTECAN | ||
Medical condition: Cancer | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: NL (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2008-002226-11 | Sponsor Protocol Number: SIMaMCI | Start Date*: 2008-10-07 |
Sponsor Name:Charité - Unversitätsmedizin Berlin | ||
Full Title: Randomized Controlled Trial of Simvastatin in Amnestic MCI Patients | ||
Medical condition: Amnestic mild cognitive impairment (MCI) denotes clinical conditions in the border zone between normal cognitive functioning and dementia. The definition of amnestic MCI by Petersen and his co-work... | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: DE (Completed) | ||
Trial results: View results |
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