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Clinical trials for Amantadine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    76 result(s) found for: Amantadine. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2021-004868-95 Sponsor Protocol Number: FETEM Start Date*: 2022-05-30
    Sponsor Name:Fundación para la Inv. Biomédica Hospital Clínico San Carlos
    Full Title: AMANTADINE AND TRANSCRANIAL MAGNETIC STIMULATION FOR TREATING FATIGUE IN MULTIPLE SCLEROSIS: PHASE III STUDY, CONTROLLED, RANDOMIZED, CROSSED OVER AND DOUBLE BLIND
    Medical condition: Fatigue in multiple sclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016143-19 Sponsor Protocol Number: 09 196 07 Start Date*: 2010-02-23
    Sponsor Name:Michael J. Fox Foundation for Parkinson’s Research
    Full Title: VALIDATION OF DYSKINESIA RATING SCALES
    Medical condition: Maladie de parkinson
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003315-63 Sponsor Protocol Number: ARPA-AMANTADINA-2012 Start Date*: 2012-10-24
    Sponsor Name:FIBHULP
    Full Title: RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, STUDY OF EFFECTIVENESS, TOLERABILITY AND SAFETY OF THERAPY WITH AMANTADINE IN DEGENERATIVE ATAXIAS
    Medical condition: Degenerative ataxias
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003945-10 Sponsor Protocol Number: 01-APN-08 Start Date*: 2009-01-20
    Sponsor Name:Centre hospitalier universitaire de nice
    Full Title: ACTION OF THE AMANTADINE ON POST STROKE APHASIC PATIENTS LANGUAGE AND COMMUNICATION
    Medical condition: post stroke chronic aphasia patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2014-001131-36 Sponsor Protocol Number: OS320-3005 Start Date*: 2014-10-23
    Sponsor Name:Osmotica Pharmaceutical Corp.
    Full Title: A Multicenter, Randomized, Placebo-controlled, Double-blind, 16 Week Study to Evaluate the Efficacy and Safety of Amantadine HCl Extended Release Tablets in Parkinson's Disease Subjects with Levodo...
    Medical condition: Parkinson's Disease Subjects with Levodopa-Induced Dyskinesias
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2021-001144-98 Sponsor Protocol Number: LUB-COV-2021-01 Start Date*: 2021-04-20
    Sponsor Name:Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie
    Full Title: The use of amantadine in the prevention of progression and treatment of COVID-19 symptoms in patients infected with the SARS-CoV-2 virus
    Medical condition: SARS-CoV-2 infection with one or more of the following symptoms: fever, cough, muscle aches, mild breathlessness, chest pain, diarrhea, nausea, vomiting, anosmia, lack of taste, sore throat, nasal ...
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004848 10084355 COVID-19 virus test positive LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001132-10 Sponsor Protocol Number: OS320-3006 Start Date*: 2014-10-23
    Sponsor Name:Osmotica Pharmaceutical Corp.
    Full Title: A Multicenter, Randomized, Placebo-controlled, Double-blind, 26 Week Study to Evaluate the Efficacy and Safety of Amantadine HCl Extended Release Tablets in Parkinson's Disease Subjects with Levodo...
    Medical condition: Parkinson's Disease Subjects with Levodopa-Induced Dyskinesias
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005723-33 Sponsor Protocol Number: amantadineSCEDI. Start Date*: 2015-03-27
    Sponsor Name:GGZ Oost Brabant
    Full Title: Efficacy of amantadine on behavioural and emotional problems and impairment of executive functioning due to acquired brain injury to the frontal lobes: a series of single case experimental design s...
    Medical condition: behavioural and emotional problems and impairment of executive functioning due to acquired brain injury to the frontal lobes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003739-20 Sponsor Protocol Number: ADS-AMT-PD302 Start Date*: 2015-04-23
    Sponsor Name:Adamas Pharmaceuticals, Inc.
    Full Title: Open-Label Safety Study of ADS-5102 (Amantadine HCl) Extended Release Capsules for the Treatment of Levodopa-Induced Dyskinesia
    Medical condition: Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10013916 Dyskinesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) AT (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-015850-39 Sponsor Protocol Number: ADS-TCAD-PO206 Start Date*: 2009-11-12
    Sponsor Name:Adamas Pharmaceuticals, Inc
    Full Title: A Randomized Open Label Study Comparing the Efficacy, Safety, and Tolerability of Oral Administration of Amantadine and Ribavirin with Oseltamivir Versus Oseltamivir to Influenza A Virus Infected I...
    Medical condition: Influenza A Virus
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-002418-18 Sponsor Protocol Number: 2021-10 Start Date*: 2022-11-09
    Sponsor Name:University Hospital Tübingen
    Full Title: AmaNtadine for NeuroenhancEment in acutE patients Study - A prospective pilot proof of concept phase IIb study in intensive and intermediate care unit patients (ANNES)
    Medical condition: Patients on Intermediate Care and Intensive Care Unit (IMC and ICU) with unresponsive wakefulness syndrome not otherwise explained
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-004543-11 Sponsor Protocol Number: 2008-517 Start Date*: 2008-10-03
    Sponsor Name:HOSPICES CIVILS DE LYON
    Full Title: COMBINA. Efficacité et tolérance des bithérapies oseltamivir + zanamivir ou oseltamivir + amantadine en comparaison avec la monothérapie oseltamivir dans le traitement de la grippe saisonnière A
    Medical condition: Grippe de type A confirmée
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022002 Influenza A virus infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001177-22 Sponsor Protocol Number: 02032021 Start Date*: 2021-04-26
    Sponsor Name:Copenhagen University Hospital, Hvidovre , Capital Region
    Full Title: Amantadine for COVID-19: A randomized, placebo controlled, double-blinded, clinical trial
    Medical condition: COVID-19
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10051905 Coronavirus infection PT
    20.0 10022891 - Investigations 10070255 Coronavirus test positive PT
    23.0 10021881 - Infections and infestations 10084382 Coronavirus disease 2019 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-006684-22 Sponsor Protocol Number: 0600801 Start Date*: 2007-06-08
    Sponsor Name:CHU Toulouse
    Full Title: Evaluation des effets à long terme de l’amantadine chez le parkinsonien souffrant de dyskinésies induites par la lévodopa : Etude randomisée en double-insu versus placebo de l’arrêt d’une prescrip...
    Medical condition: maladie de parkinson
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013113 Disease Parkinson's LLT
    9.1 10013916 Dyskinesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003738-24 Sponsor Protocol Number: ADS-AMT-PD304 Start Date*: 2015-04-23
    Sponsor Name:Adamas Pharmaceuticals, Inc.
    Full Title: ADS-5102 (Amantadine HCl) Extended Release Efficacy and Safety Study in Parkinson's Disease Patients with Levodopa-Induced Dyskinesia
    Medical condition: Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029205 - Nervous system disorders 10013916 Dyskinesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-002986-39 Sponsor Protocol Number: DXM/AMT Start Date*: 2011-09-12
    Sponsor Name:Profil Institut für Stoffwechselforschung GmbH
    Full Title: A Phase IIa, Double-Blind, Placebo-Controlled, Randomised, Fourfold Cross-Over Study to Investigate the Glucose Lowering Effects of Dextromethorphan and Amantadine in Subjects with Type 2 Diabetes ...
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    14.0 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002964-90 Sponsor Protocol Number: 27919 Start Date*: 2011-05-05
    Sponsor Name:Newron Pharmaceuticals SpA
    Full Title: A phase III, double-blind, placebo-controlled, randomised trial to determine the efficacy and safety of a dose range of 50 to 100 mg/day of safinamide, as add-on therapy, in subjects with idiopathi...
    Medical condition: Idiopathic Parkinson's Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FI (Prematurely Ended) FR (Completed) HU (Completed) ES (Completed) NL (Completed) EE (Completed) AT (Completed) SK (Completed) DE (Completed) GB (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2008-001694-15 Sponsor Protocol Number: 060255 Start Date*: 2008-06-11
    Sponsor Name:Afdeling for Traumatisk Hjerneskade
    Full Title: En multicenter, randomiseret, placebo-kontrolleret studie af effekten af amantadin til fremme af bedring efter svær traumatisk hjerneskade: Amantadin-studiet
    Medical condition: Projektets formål er at undersøge, om lægemidlet amantadin bedrer patienter som er svært bevidsthedssvækkede pga. nylig svær traumatisk hjerneskade.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002650-59 Sponsor Protocol Number: SP824 Start Date*: 2005-02-03
    Sponsor Name:SCHWARZ BIOSCIENCES
    Full Title: A phase 3b, open-label, multicentre, multinational trial to assess the tolerability of switching subjects from ropinerole, pramipexole or cabergoline to the rotigotine transdermal system and its ef...
    Medical condition: Idiopathic Parkinson's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-023678-38 Sponsor Protocol Number: GR-2008-1138784 sottostudio Start Date*: 2011-04-20
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: High-field structural and functional MRI to investigate the substrates of fatigue in multiple sclerosis and to monitor the effect of tailored treatments.Pharmacological substudy.
    Medical condition: patients with multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028245 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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