- Trials with a EudraCT protocol (231)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
231 result(s) found for: Bone graft.
Displaying page 1 of 12.
EudraCT Number: 2006-004420-37 | Sponsor Protocol Number: 280 | Start Date*: 2007-05-29 | |||||||||||
Sponsor Name:OSIRIS | |||||||||||||
Full Title: モA Phase III, Randomized, Double Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Prochymalル (Ex-vivo Cultured Adult Human Mesenchymal Stem Cells) Infusion for the Treatment o... | |||||||||||||
Medical condition: Subjects must have steroid refractory treatment of Grades B-D acute GVHD secondary to allogeneic HSCT (stem cells sources: bone marrow, peripheral blood stem cells, or cord blood cells) or DLI. | |||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) GB (Completed) ES (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2006-005019-81 | Sponsor Protocol Number: INO-0106 | Start Date*: 2006-12-22 | |||||||||||
Sponsor Name:OPi | |||||||||||||
Full Title: A European Open-Label, Multicentre, Phase II Study of Inolimomab in the Treatment of Primary Steroid Resistant Acute Graft versus Host Disease (aGvHD) following allogeneic Stem Cell Transplantation... | |||||||||||||
Medical condition: For treatment of patients with Primary Steroid Resistant Acute Graft versus Host Disease (aGvHD) following allogeneic Stem Cell Transplantation for Hematological Malignancies in Adult patients | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2007-004310-14 | Sponsor Protocol Number: TJB0703 | Start Date*: 2007-12-13 | |||||||||||||||||||||
Sponsor Name:CHU-ULG | |||||||||||||||||||||||
Full Title: Infusion of mesenchymal stem cells as treatment for steroid resistant grade II to IV acute GVHD or poor graft function: a multicenter phase II study | |||||||||||||||||||||||
Medical condition: Steroid resistant grade II to IV acute graft-versus-host disease (GVHD) or poor graft function after allogeneic hematopoietic cell transplantation | |||||||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: BE (Completed) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2021-004529-57 | Sponsor Protocol Number: EQ-100-02 | Start Date*: 2022-06-24 | ||||||||||||||||
Sponsor Name:Equillium Inc. | ||||||||||||||||||
Full Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Itolizumab in Combination with Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease | ||||||||||||||||||
Medical condition: Acute Graft Versus Host Disease | ||||||||||||||||||
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Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: IT (Trial now transitioned) ES (Ongoing) FR (Trial now transitioned) BE (Trial now transitioned) DE (Trial now transitioned) PT (Trial now transitioned) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2005-001925-27 | Sponsor Protocol Number: 06-MI-04 | Start Date*: 2009-10-05 | |||||||||||
Sponsor Name:Great Ormond Street Hospital For Children NHS Trust | |||||||||||||
Full Title: Phase I/II clinical trial of T cell suicide gene therapy following haploidentical stem cell transplantation | |||||||||||||
Medical condition: Graft-versus-host disease (GVHD) resulting from haploidentical bone marrow or blood stem cell transplantation | |||||||||||||
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Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2010-024297-19 | Sponsor Protocol Number: TJB1016P1 | Start Date*: 2011-09-13 | ||||||||||||||||
Sponsor Name:CHU de Liege | ||||||||||||||||||
Full Title: Allogeneic hematopoietic cell transplantation from HLA-matched donors after reduced-intensity conditioning: a phase II randomized study comparing 2 GVHD prophylaxis regimen | ||||||||||||||||||
Medical condition: Hematologic malignancies treated by reduced-intensity conditioning allogeneic transplants. | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: BE (Completed) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2005-006178-86 | Sponsor Protocol Number: EBMT-LE-0601 | Start Date*: 2007-08-03 | |||||||||||
Sponsor Name:European group for Blood and Marrow Transplantation | |||||||||||||
Full Title: A randomized placebo-controlled trial comparing cyclosporine plus steroids with or without Myfortic® as primary treatment for extensive chronic graft-versus host disease | |||||||||||||
Medical condition: patients with newly diagnosed (first episode) extensive chronic Graft versus Host Disease (cGvHD) post allogeneic transplantation for any primary diagnosis | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Prematurely Ended) NL (Prematurely Ended) ES (Ongoing) SE (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2010-022780-35 | Sponsor Protocol Number: 10-005 | Start Date*: 2011-07-06 | |||||||||||
Sponsor Name:THERAKOS, Inc. | |||||||||||||
Full Title: A Randomized Controlled Study of Extracorporeal Photopheresis (ECP) Therapy with UVADEX™ for the Treatment of Patients with Moderate to Severe Chronic Graft-versus-Host Disease (cGvHD) | |||||||||||||
Medical condition: Chronic graft-versus-host disease (cGvHD) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) DE (Completed) AT (Completed) ES (Completed) IT (Completed) HU (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-000894-22 | Sponsor Protocol Number: MAGIC-HR-ECP | Start Date*: 2019-12-10 | |||||||||||
Sponsor Name:Department of Stem Cell Transplantation - University Medical Center Hamburg-Eppendorf | |||||||||||||
Full Title: Phase II multicenter study of extracorporeal photopheresis with UvadexTM plus standard steroid treatment for high risk acute Graft-versus-Host Disease | |||||||||||||
Medical condition: New onset high risk acute GvHD following allogeneic SCT | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) AT (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-002503-26 | Sponsor Protocol Number: X16082 | Start Date*: 2017-03-14 | ||||||||||||||||
Sponsor Name:Fundación Pública Andaluza para la Gestión en Salud de Sevilla (FISEVI) | ||||||||||||||||||
Full Title: Phase Ib/II trial to evaluate safety and efficacy of oral ixazomib in combination with sirolimus and tacrolimus in the prophylaxis of chronic graft-versus-host disease | ||||||||||||||||||
Medical condition: Adult patiens after allogeneic stem cell transplantation | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: ES (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2008-002310-22 | Sponsor Protocol Number: 35/2008/O/Sper | Start Date*: 2008-06-16 | ||||||||||||||||
Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI | ||||||||||||||||||
Full Title: A multicenter phase II trial of Recipient pre-treatment with Short-Term Rapamycin for the prevention of acute GVHD after hematopoietic stem cell transplantation in Elderly Patients | ||||||||||||||||||
Medical condition: Graft Versus Host Disease | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: IT (Completed) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2010-018594-37 | Sponsor Protocol Number: EMN-alloRIC2010 | Start Date*: 2013-01-24 | ||||||||||||||||
Sponsor Name:European Myeloma Network | ||||||||||||||||||
Full Title: European Myeloma Network sequential phase I / phase II trial on RIC allogeneic transplantation: an optimized program for high risk relapsed patients | ||||||||||||||||||
Medical condition: Allogeneic transplantation for patients with multiple myeloma | ||||||||||||||||||
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Population Age: Adults | Gender: Male, Female | |||||||||||||||||
Trial protocol: SE (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-004806-14 | Sponsor Protocol Number: TKS-2014-001 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:Therakos, Inc. | |||||||||||||
Full Title: Single-Arm Study to Assess the Efficacy of UVADEX® (methoxsalen) Sterile Solution in Conjunction with the THERAKOS® CELLEX® Photopheresis System in Pediatric Patients with Steroid-Refractory Acute ... | |||||||||||||
Medical condition: Acute graft-versus-host disease (aGvHD) | |||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) HU (Completed) GB (Completed) IT (Completed) ES (Completed) AT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2006-006577-25 | Sponsor Protocol Number: 070101 | Start Date*: 2007-07-25 | |||||||||||
Sponsor Name:Karolinska Institutet | |||||||||||||
Full Title: A prospective randomized study comparing rapamune and tacrolimus vs. cyclosporine and methotrexate as immune prophylaxis in allogeneic hematopoietic stem cell transplantation, using HLA-A, -B, -DRB... | |||||||||||||
Medical condition: Graft versus host disease prophylaxis in patients receiving stem cell transplantation due to: chronic myeloid leukemia (CML) in 1st or 2nd chronic phase, acute myeloid leukemia (AML) in complete re... | |||||||||||||
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Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Completed) FI (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2008-005862-30 | Sponsor Protocol Number: MHH-Pre-GvHD-001 | Start Date*: 2009-02-23 | |||||||||||
Sponsor Name:Medizinische Hochschule Hannover | |||||||||||||
Full Title: Pre-emptive therapy of acute graft versus host disease according to specific proteomic patterns after allogeneic hematopoietic stem cell transplantation. | |||||||||||||
Medical condition: Pre-emptive therapy of acute graft versus host disease with prednisolone according to specific proteomic patterns after allogeneic hematopoietic stem cell transplantation. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-000862-31 | Sponsor Protocol Number: GLAS | Start Date*: 2017-09-28 | |||||||||||||||||||||||||||||||
Sponsor Name:Grupo Español de Trasplante Hematopoyético y Terapia Celular (GETH) | |||||||||||||||||||||||||||||||||
Full Title: A phase Ib/IIa pilot trial of the oral Hedgehog Signalling Inhibitor, Glasdegib, in Patients with sclerotic chronic graft-versus-host disease refractory to second-line treatment | |||||||||||||||||||||||||||||||||
Medical condition: Adult patiens with sclerotic chronic graft-versus-host disease refractory to second-line treatment. | |||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||
Trial protocol: ES (Completed) | |||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-000538-78 | Sponsor Protocol Number: INCB39110-301 | Start Date*: 2017-09-14 | ||||||||||||||||||||||||||
Sponsor Name:Incyte Corporation | ||||||||||||||||||||||||||||
Full Title: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids for the Treatment of First-Line Acute Graft Versus-Host Disease | ||||||||||||||||||||||||||||
Medical condition: Male or female, 18 years of age or older who have received an allogeneic hematopoietic stem cell transplant (allo-HSCT) and have developed Grade II to IV acute GVHD | ||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: HU (Prematurely Ended) CZ (Prematurely Ended) GB (Prematurely Ended) BE (Completed) AT (Prematurely Ended) PT (Prematurely Ended) ES (Prematurely Ended) NL (Prematurely Ended) GR (Completed) FI (Completed) IT (Prematurely Ended) | ||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2007-005009-24 | Sponsor Protocol Number: INO-0107 | Start Date*: 2008-05-15 | |||||||||||
Sponsor Name:EUSA Pharma | |||||||||||||
Full Title: An international randomised, multicentre, parallel-group, Phase III comparative study of inolimomab against usual care in the Treatment of Primary Steroid Refractory Acute Graft versus Host Disease... | |||||||||||||
Medical condition: Steroid refractory acute Graft versus Host Disease (aGvHD) after Allogeneic Haematopoietic Stem Cell Transplantation in adult patients | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Completed) BE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2011-003237-33 | Sponsor Protocol Number: HO112 | Start Date*: 2013-11-21 | ||||||||||||||||
Sponsor Name:HOVON Foundation | ||||||||||||||||||
Full Title: Treatment of severe GVHD after allogeneic hematopoietic stem cell transplanatation with MSCs and steroid versus steroids alone. A prospective double-blind placebo-controlled randomized phase III t... | ||||||||||||||||||
Medical condition: Graft Versus Host Disease | ||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: NL (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2004-000232-91 | Sponsor Protocol Number: AP-AS-21-DE | Start Date*: 2004-11-15 |
Sponsor Name:Fresenius Biotech GmbH | ||
Full Title: GvHD prophylaxis with ATG-Fresenius S in allogeneic Stem Cell Transplantation from matched unrelated donors: A randomised phase III multicenter trial comparing a standard GvHD prophylaxis with cycl... | ||
Medical condition: AML, ALL, MDS, CML | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: FI (Completed) ES (Completed) IT (Completed) | ||
Trial results: (No results available) |
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