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Clinical trials for Brinzolamide

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    30 result(s) found for: Brinzolamide. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2019-000921-39 Sponsor Protocol Number: PH-BRINLOL-01 Start Date*: 2019-04-24
    Sponsor Name:PHARMATHEN SA
    Full Title: A prospective, phase III, multicenter, randomized, investigator-masked, parallel groups, non-inferiority clinical trial for the comparison of efficacy and safety and of a generic fixed combination ...
    Medical condition: open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed) CY (Completed)
    Trial results: View results
    EudraCT Number: 2010-024513-31 Sponsor Protocol Number: C-10-041 Start Date*: 2011-06-15
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Efficacy and Safety of Brinzolamide 10 mg/ml / Brimonidine 2 mg/ml Eye Drops, Suspension Compared to Brinzolamide 10 mg/ml Eye Drops, Suspension plus Brimonidine 2 mg/ml Eye Drops, Solution in Pati...
    Medical condition: Patients with open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) PT (Completed) HU (Completed) LT (Completed) DE (Completed) BE (Prematurely Ended) NL (Completed) AT (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-003692-12 Sponsor Protocol Number: AZ02 Start Date*: 2012-05-09
    Sponsor Name:AZAD Pharma AG
    Full Title: A phase III , multicentre, randomised, investigator-masked, cross-over, comparative efficacy study of a generic Brinzolamide 10 mg/ml ophthalmic suspension (Azad Pharma AG) and Brinzolamide 10 mg/m...
    Medical condition: Patients suffering from open angle glaucoma and ocular hypertension with an elevated IOP, higher than 22mmHg and and lower or equal than 35 mmHg
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2016-000946-69 Sponsor Protocol Number: AZ07 Start Date*: 2016-07-05
    Sponsor Name:AZAD Pharma AG
    Full Title: A PHASE III, MULTICENTRE, RANDOMISED, INVESTIGATOR-MASKED, CROSS- OVER, COMPARATIVE CLINICAL TRIAL EVALUATING THE EFFICACY AND SAFETY OF THE GENERIC BRINZOLAMIDE 10 MG/ML + TIMOLOL 5 MG/ML EYE DROP...
    Medical condition: Decrease of intraocular pressure (IOP) in adult patients with open-angle glaucoma or ocular hypertension for whom monotherapy provides insufficient IOP reduction
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    19.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) AT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2013-001793-21 Sponsor Protocol Number: CPA12001 Start Date*: 2013-08-06
    Sponsor Name:PHARMATHEN S.A.
    Full Title: Efficacy and tolerability of brinzolamide in patients with elevated intraocular pressure: a double-blind, randomized, parallel, verum-controlled trial.
    Medical condition: intraocular pressure increased
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10022806 Intraocular pressure increased PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2005-004766-16 Sponsor Protocol Number: C-05-10 Start Date*: 2006-02-17
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Comparison of Safety and Efficacy of Brinzolamide/Timolol Fixed Combination vs COSOPT in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open Angle Glaucoma or Ocular Hypertension ICD: H40.1/H40.0
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) BE (Completed) GB (Completed) LT (Completed) LV (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-024512-34 Sponsor Protocol Number: C-10-040 Start Date*: 2011-05-17
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Safety and IOP-Lowering Efficacy of Brinzolamide 10 mg/ml / Brimonidine 2 mg/ml Fixed Combination Eye Drops, Suspension compared to Brinzolamide 10 mg/ml Eye Drops, Suspension and Brimonidine 2 mg/...
    Medical condition: Open-angle glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004853 10030856 Open-angle glaucoma LLT
    14.1 100000004853 10020784 Hypertension ocular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) PT (Completed) LV (Completed) DE (Completed) HU (Completed) LT (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003627-37 Sponsor Protocol Number: IT-04-04 Start Date*: 2006-09-22
    Sponsor Name:ALCON ITALIA
    Full Title: Hypotonic efficacy and tollerability of concomitant supply of Travoprost e Brinzolamide vs dorzolamide-timololo in fixed association in patient with glaucoma or ocular hypertension clinical study,...
    Medical condition: Patient with glaucoma or ocular hypertension bilateral non controlled
    Disease: Version SOC Term Classification Code Term Level
    6.1 10018307 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-002780-13 Sponsor Protocol Number: C-07-63 Start Date*: 2008-09-04
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A Three-Month, Multicenter, Double-Masked Study Comparing the Safety and Efficacy of the Fixed Combination Travoprost + Brinzolamide Eye Drops, Suspension vs Travatan vs Azopt in Patients with Open...
    Medical condition: open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030348 Open angle glaucoma PT
    9.1 10015919 Eye disorders SOC
    9.1 10030043 Ocular hypertension LLT
    9.1 10030043 Ocular hypertension PT
    9.1 10015919 Eye disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Prematurely Ended) ES (Completed) BE (Completed) HU (Prematurely Ended) GB (Prematurely Ended) IT (Prematurely Ended) PT (Prematurely Ended) AT (Prematurely Ended) LV (Completed) SE (Prematurely Ended) EE (Prematurely Ended) LT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-002524-12 Sponsor Protocol Number: BNZ-20-01-2022 Start Date*: 2023-04-13
    Sponsor Name:AZAD Pharma AG
    Full Title: A prospective, phase III, multicenter, randomized, investigator-blinded, two-arm, parallel groups, non-inferiority clinical trial for the comparison of efficacy and safety of a preservative-free Br...
    Medical condition: GLAUCOMA , OCCULAR HYPERTENSION
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-000079-18 Sponsor Protocol Number: PHN-BBFC-NI101 Start Date*: 2020-03-18
    Sponsor Name:Pharmathen S.A.
    Full Title: A phase III, multicentre, prospective, randomized, assessor-blinded, two-arm, parallel group, therapeutic non-inferiority 3-month clinical trial to compare the efficacy and safety of a generic fixe...
    Medical condition: Open-angle glaucoma (OAG) or ocular hypertension (OHT)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10015919 Eye disorders SOC
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-002781-66 Sponsor Protocol Number: C-08-16 Start Date*: 2008-12-04
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A twelve-month, multicenter, double-masked study of Travoprost / Brinzolamide fixed combination QD AM and Travoprost / Brinzolamide fixed combination QD PM versus COSOPT BID in patients with open-a...
    Medical condition: Open-angle glaucoma or Ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030348 Open angle glaucoma PT
    9.1 10015919 Eye disorders SOC
    9.1 10030043 Ocular hypertension LLT
    9.1 10030043 Ocular hypertension PT
    9.1 10015919 Eye disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) ES (Completed) BE (Completed) SE (Prematurely Ended) DK (Prematurely Ended) PL (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004201-29 Sponsor Protocol Number: CM-05-08/HU Start Date*: 2006-06-01
    Sponsor Name:Alcon Hungarian ltd
    Full Title: THE EFFICACY AND SAFETY OF TIMOLOL MALEATE 0.5% COMPARED TO BRINZOLAMIDE 1% EACH GIVEN TWICE DAILY WHEN ADDED TO TRAVOPROST 0.004% GIVEN EACH EVENING IN PRIMARY OPEN-ANGLE GLAUCOMA OR OCULAR HYPERT...
    Medical condition: Increased intraocular pressure and glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015795-10 Sponsor Protocol Number: SMA-09-19-SVN Start Date*: 2009-11-12
    Sponsor Name:Alcon d.o.o.
    Full Title: Assessing the safety and efficacy of switching to Azarga (Brinzolamide/Timolol Fixed Combination), as replacement therapy in patients with uncontrolled intraocular pressure
    Medical condition: uncontrolled intraocular pressure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2007-005936-99 Sponsor Protocol Number: C-07-16 Start Date*: 2008-11-19
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Effects of Topical Hypotensive Drugs on Circadian Ocular Perfusion Pressure and Ocular Blood Flow in Patients with Open-Angle Glaucoma
    Medical condition: Open-Angle Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2007-000811-27 Sponsor Protocol Number: Gl-HG-szem1-07-001 Start Date*: 2007-05-09
    Sponsor Name:Department of Ophthalmology, SEmmelweis University
    Full Title: Evaluation of additional intraocular pressure reduction with once daily, evening administration of travoprost 0.004%, once daily, evening administration of travoprost 0.004%/timolol 0.5% fixed comb...
    Medical condition: Open-angle glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002750-38 Sponsor Protocol Number: C-08-09 Start Date*: 2008-10-22
    Sponsor Name:Alcon Research Ltd
    Full Title: 24-hour IOP control with Travoprost / Brinzolamide fixed combination once-daily (QD)in the evening vs TRAVATAN
    Medical condition: Open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015919 Eye disorders SOC
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-000736-15 Sponsor Protocol Number: GLH694-P001 Start Date*: 2015-09-14
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Additive Effect of Twice Daily Brinzolamide 1% /Brimonidine 0.2% Fixed Dose Combination as an Adjunctive Therapy to a Prostaglandin Analogue
    Medical condition: Ocular Hypertension Open-angle Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) GB (Completed) FR (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2009-015796-27 Sponsor Protocol Number: SMA-09-18 Start Date*: 2009-11-12
    Sponsor Name:Alcon d.o.o.
    Full Title: Patient Preference Comparison of Azarga versus Cosopt, after Single Doses in Patients with Open-Angled Glaucoma or Ocular Hypertension
    Medical condition: Open-angle glaucoma or ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2016-000176-20 Sponsor Protocol Number: GLJ576-P001 Start Date*: 2016-05-29
    Sponsor Name:Alcon Research Ltd
    Full Title: Safety and Efficacy with Twice Daily Brinzolamide 1% / Brimonidine 0.2% (SIMBRINZA) as an Adjunctive Therapy to Travoprost 0.004% / Timolol 0.5% (DUOTRAV)
    Medical condition: Ocular Hypertension Open-angle Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    19.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) BE (Completed) GB (Prematurely Ended) DE (Completed) GR (Completed) FR (Completed) NL (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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