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Clinical trials for Dying

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    29 result(s) found for: Dying. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2007-004369-16 Sponsor Protocol Number: MJ/LPGB/12/2006 Start Date*: 2007-11-29
    Sponsor Name:St Raphael's Hospice, Surrey
    Full Title: ''Evaluation of the efficacy of 'TRANS-DERMAL NITRATE' in reducing the severity of 'death-rattle' (i.e 'terminal lung secretions' ) in patients dying from end stage malignancy''
    Medical condition: 'Death-rattle' (i.e 'terminal lung secretions') in adult patients dying from end-stage malignancy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-002287-14 Sponsor Protocol Number: Reutelen Start Date*: 2016-12-23
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: Death rattle in the dying phase: is prophylactic treatment useful?
    Medical condition: Death rattle in the dying phase
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10031920 Other diseases of trachea and bronchus, not elsewhere classified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005009-30 Sponsor Protocol Number: Start Date*: 2016-05-04
    Sponsor Name:Gloucestershire Hospitals NHS Foundation Trust and
    Full Title: An open label, randomised controlled feasibility pilot study to evaluate whether nasal fentanyl alone and in combination with buccal midazolam give better symptom control to dying patients when com...
    Medical condition: Adult hospice in-patients with terminal cancer who are thought to be in the last 1 - 2 weeks of life
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10059513 Palliative care PT
    20.0 100000004864 10048683 Advanced cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-002192-25 Sponsor Protocol Number: ABR-62110 Start Date*: 2017-12-06
    Sponsor Name:Center of Expertise in Palliative Care, Maastricht University Medical Centre
    Full Title: Neurotoxic adverse effects of morphine and oxycodone in continuous subcutaneous infusion for treatment of pain in terminal patients with diminished renal function: a Randomized Controlled Trial.
    Medical condition: - The subject is in the terminal phase, i.e. death in the near future is expected by the treating physician; - The subject has a diminished renal function, defined as an eGFR < 50 ml/min/1.73m2; - ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-003206-69 Sponsor Protocol Number: ASST-FARM-CAR_STEROHF-2022 Start Date*: 2023-01-30
    Sponsor Name:AZIENDA SOCIO SANITARIA TERRITORIALE DEGLI SPEDALI CIVILI DI BRESCIA
    Full Title: A multicenter, randomized, open-label, controlled study to evaluate the efficacy and safety of corticoSTEROids added to standard therapy in patients with Acute Heart Failure (STERO-AHF)
    Medical condition: patients with Acute Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007556 Cardiac failure acute PT
    20.0 10007541 - Cardiac disorders 10007556 Cardiac failure acute PT
    20.0 10007541 - Cardiac disorders 10066332 Acute cardiac insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-004789-36 Sponsor Protocol Number: 173-01 Start Date*: 2022-06-29
    Sponsor Name:Universität Heidelberg
    Full Title: Randomized, controlled trial of the use of intranasal midazolam for the treatment of terminal agitation in palliative care patients
    Medical condition: Terminal agitation in the final phase
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002636-31 Sponsor Protocol Number: APHP211034 Start Date*: 2022-09-15
    Sponsor Name:Assistance Publique Hôpitaux de Paris/DRCI
    Full Title: Piperacillin-tazobactam and temocillin as carbapenem-alternatives for the treatment of severe infections due to extended-spectrum beta-lactamase–producing Gram-negative Enterobacteriaceae in the in...
    Medical condition: severe infections due to extended-spectrum beta-lactamase–producing Gram-negative Enterobacteriaceae
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-001700-42 Sponsor Protocol Number: APHP200410 Start Date*: 2020-05-06
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Efficacy of captopril nebulization in Covid-19 patients suffering of SARS-CoV-2 pneumonia. A randomized phase II study
    Medical condition: Patient ≥18 with SARS Cov 2 pneumonia requiring oxygen administration.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10051905 Coronavirus infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2020-004627-16 Sponsor Protocol Number: 70233 Start Date*: 2020-11-25
    Sponsor Name:Helsinki University Hospital
    Full Title: Clinical Validation of Quantitative Flutemetamol PET/CT in Cardiac Amyloidosis
    Medical condition: Cardiac amyloidosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007509 Cardiac amyloidosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001616-18 Sponsor Protocol Number: TACTIC-COVID Start Date*: 2020-04-18
    Sponsor Name:Fundació Clinic per a la Recerca Biomèdica
    Full Title: Treatment with inhaled corticoids in patients with COVID-19 admitted to hospital with pneumonia
    Medical condition: COVID19
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10051905 Coronavirus infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001696-32 Sponsor Protocol Number: GC2004 Start Date*: 2020-05-08
    Sponsor Name:Instituto Grifols, S.A
    Full Title: A Multicenter, Randomized, Open-label Parallel Group Pilot Study to Evaluate Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) plus Standard Medical Treatment (SMT) versus SMT alo...
    Medical condition: Patients with Mild to Moderate Coronavirus Disease (COVID-19)
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10051905 Coronavirus infection PT
    23.0 10021881 - Infections and infestations 10053983 Corona virus infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2020-001953-36 Sponsor Protocol Number: GC2005 Start Date*: 2020-05-08
    Sponsor Name:Instituto Grifols, S.A
    Full Title: A Multicenter, Randomized, Open-label, Parallel Group Pilot Study to Evaluate the Safety and Efficacy of Prolastin® plus Standard Medical Treatment (SMT) versus SMT alone in Hospitalized Subjects w...
    Medical condition: Patients with Coronavirus Disease (COVID-19)
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10051905 Coronavirus infection PT
    23.0 10021881 - Infections and infestations 10053983 Corona virus infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2019-001621-27 Sponsor Protocol Number: 201900242 Start Date*: 2021-02-24
    Sponsor Name:University Medical Center Groningen
    Full Title: A pilot study on oral s-ketamine for depression and demoralization in patients with advanced cancer receiving palliative care
    Medical condition: Major depressive disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001740-26 Sponsor Protocol Number: ATOMIC2 Start Date*: 2020-05-05
    Sponsor Name:University of Oxford, Clinical Trials and Research Governance
    Full Title: A multi-centre open-label two-arm randomised superiority clinical trial of Azithromycin versus usual care In Ambulatory COVID-19 (ATOMIC2)
    Medical condition: COVID-19
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10051905 Coronavirus infection PT
    20.0 10022891 - Investigations 10070255 Coronavirus test positive PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2020-001039-29 Sponsor Protocol Number: ESCAPE Start Date*: 2020-04-01
    Sponsor Name:HELLENIC INSTITUTE FOR THE STUDY OF SEPSIS
    Full Title: EFFICIENCY IN MANAGEMENT OF ORGAN DYSFUNCTION ASSOCIATED WITH INFECTION BY THE NOVEL SARS-CoV-2 VIRUS (COVID-19) THROUGH A PERSONALIZED IMMUNOTHERAPY APPROACH: THE ESCAPE CLINICAL TRIAL
    Medical condition: Organ dysfunction by the novel SARS-Cov-2 virus
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10035738 Pneumonia viral NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005768-74 Sponsor Protocol Number: ImmunoSep Start Date*: 2021-02-18
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: PERSONALIZED IMMUNOTHERAPY IN SEPSIS: A MULTICENTRE AND MULTINATIONAL, DOUBLE-BLIND, DOUBLE-DUMMY RANDOMIZED CLINICAL TRIAL (THE IMMUNOSEP TRIAL)
    Medical condition: Sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040053 Sepsis secondary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed) NL (Completed) DE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022247-37 Sponsor Protocol Number: BDP-GVHD-03 Start Date*: 2010-11-24
    Sponsor Name:Soligenix, Inc.
    Full Title: A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER STUDY OF THE SAFETY AND EFFICACY OF ORBEC® (ORAL BECLOMETHASONE 17,21-DIPROPIONATE) IN CONJUNCTION WITH TEN DAYS OF HIGH-DOSE P...
    Medical condition: Patients with acute gastrointestinal Graft Versus Host Disease.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10064677 Graft versus host disease in intestine LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-003590-10 Sponsor Protocol Number: HM19/123658 Start Date*: 2019-10-30
    Sponsor Name:University of Leeds
    Full Title: Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma: A phase III trial to compare standard and frailty-adjusted induction therapy with ixazomib, lena...
    Medical condition: Newly diagnosed multiple myeloma
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004851 10028229 Multiple myelomas HLT
    20.0 100000004864 10028566 Myeloma LLT
    21.0 100000004864 10028228 Multiple myeloma LLT
    21.0 100000004864 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-007053-51 Sponsor Protocol Number: 003/APR06 Start Date*: 2007-07-02
    Sponsor Name:Gloucestershire Hospitals NHS Foundation Trust
    Full Title: Diamorphine or alfentanil for subcutaneous use in hospice in-patients
    Medical condition: Palliative Care
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059513 Palliative care LLT
    9.1 10059513 Palliative care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005838-19 Sponsor Protocol Number: 2011.697 Start Date*: 2012-12-28
    Sponsor Name:Hospics Civils de Lyon
    Full Title: MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF THE RESECTION OF GLIOBLASTOMAS - THE RESECT STUDY
    Medical condition: Glioblastoma
    Disease: Version SOC Term Classification Code Term Level
    19.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10018336 Glioblastoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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