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Clinical trials for Ex vivo

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    318 result(s) found for: Ex vivo. Displaying page 1 of 16.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2023-000171-13 Sponsor Protocol Number: P23 Start Date*: 2023-08-23
    Sponsor Name:leiden university medical center
    Full Title: SGM-101 tumor-targeted fluorescence endoscopy to enable discrimination of malignant from benign tissue in rectal polyps with suspected T1 adenocarcinoma or high grade dysplasia: a feasibility study
    Medical condition: Early rectal cancer/ big polyps with suspected T1 rectal cancer.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    20.0 10017947 - Gastrointestinal disorders 10038074 Rectal polyp PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-002226-76 Sponsor Protocol Number: 6.1 Start Date*: 2012-11-13
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: High “on treatment” platelet reactivity in the Intensive Care Unit
    Medical condition: mixed medical intensive care unit patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-010078-39 Sponsor Protocol Number: HeLIX Start Date*: 2009-06-03
    Sponsor Name:Academic Medical Center
    Full Title: The effect of helium on the immune system ex vivo
    Medical condition: Healthy volunteers, Effects of helium on the immune system ex vivo
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-006141-19 Sponsor Protocol Number: UMCG-RR#202000930 Start Date*: 2021-05-21
    Sponsor Name:University Medical Center Groningen
    Full Title: Fluorescence guided surgery for intra-operative detection of meningioma using Bevacizumab-IRDye800CW
    Medical condition: meningioma
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10027191 Meningioma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004013-15 Sponsor Protocol Number: 920'110 Start Date*: 2006-01-11
    Sponsor Name:Bioforce AG
    Full Title: Effects of Echinaforce®-treatment on the response of ex vivo stimulated blood cells
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022846-26 Sponsor Protocol Number: 1015 Start Date*: 2010-11-08
    Sponsor Name:University Hospital of Grenoble
    Full Title: Réversion de l'effet anticoagulant des nouveaux antithrombotiques anti Xa et anti IIa par des médicaments hémostatiques spécifiques ou non spécifiques : étude ex vivo chez le volontaire sain.
    Medical condition: volontaires sains
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003133-18 Sponsor Protocol Number: NL.58570.091.16 Start Date*: 2017-01-19
    Sponsor Name:radboudumc
    Full Title: Preoperative staging by combidex MRI in patients with resectable esophageal carcinoma, a feasibility study
    Medical condition: Detection of locoregional lymph node metastases in patients with resectable esophageal carcinoma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003836-22 Sponsor Protocol Number: FLG-V001 Start Date*: 2019-12-11
    Sponsor Name:HUS Helsinki University Hospital
    Full Title: TWO-STAGE, TWO-ARM, OPEN-LABEL PHASE II STUDY OF VENETOCLAX IN COMBINATION WITH AZACYTIDINE IN ACUTE MYELOID LEUKEMIA PATIENTS SELECTED USING EX VIVO DRUG SENSITIVITY SCREENING
    Medical condition: Acute myeloid leukemia in patients who are non-fit for standard induction therapy (except acute promyelocytic leukemia) and present with de novo, secondary, released or refractory AML
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10000880 Acute myeloid leukaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004745-17 Sponsor Protocol Number: UMCG:201800879 Start Date*: 2019-03-28
    Sponsor Name:University Medical Center Groningen
    Full Title: Detection of Early Esophageal Cancer by Near-Infrared Fluorescence molecular Endoscopy using Bevacizumab-800CW
    Medical condition: Patients with Barretts esophagus and there is a suspicion for at least low grade dysplasia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004738-14 Sponsor Protocol Number: NanoGSkin-CB-2019 Start Date*: 2020-04-28
    Sponsor Name:Red Andaluza de Diseño y Traslación de Terapias Avanzadas - Fundación Pública Andaluza Progreso y Salud
    Full Title: PHASE II CLINICAL TRIAL EVALUATING THE SAFETY AND EFFICACY OF A TISSUE ENGINEERED AUTOLOGOUS SKIN SUBSTITUTE RECONSTRUCTIVE SURGERY FOR BASAL CELL CARCINOMA.
    Medical condition: Reconstructive skin surgery in basal cell cancer (Mohs surgery)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10004146 Basal cell carcinoma PT
    21.1 100000004865 10064974 Mohs micrographic surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000608-16 Sponsor Protocol Number: 5466 Start Date*: 2011-12-21
    Sponsor Name:The Newcastle upon Tyne Hospitals NHS Foundation Trust [...]
    1. The Newcastle upon Tyne Hospitals NHS Foundation Trust
    2. The Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: To evaluate the safety and effectiveness of human ex vivo expanded autologous limbal stem cells for the treatment of unilateral total limbal stem cell deficiency
    Medical condition: unilateral total limbal stem cell deficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004280-32 Sponsor Protocol Number: AG10-301 Start Date*: 2019-05-10
    Sponsor Name:Eidos Therapeutics, Inc.
    Full Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of AG10 in Subjects with Symptomatic Transthyretin Amyloid Cardiomyopathy (ATTRIBUTE-CM Trial)
    Medical condition: Symptomatic Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10002020 Amyloid cardiomyopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DK (Completed) IE (Completed) PT (Completed) ES (Ongoing) NL (Completed) BE (Completed) HU (Completed) PL (Completed) GR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004560-21 Sponsor Protocol Number: NL_ABR-43379 Start Date*: 2013-04-03
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The effect of ticagrelor on the adenosine system
    Medical condition: We will study in healthy volunteers the effect of ticagrelor on the vasodilator effect of dipyridamole
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-019643-19 Sponsor Protocol Number: 3/19/2010 Start Date*: 2011-01-13
    Sponsor Name:Medizinische Universität Wien, Univ.Klinik f.Innere Medizin I, Abt.f.Hämatologie u.Hämostaseologie
    Full Title: The effect of clopidogrel and prasugrel with and without acetylsalicylic acid (ASA) on hemostatic system activation at the site of plug formation in vivo in man
    Medical condition: coronary artery disease and acute coronary syndrome
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-002804-19 Sponsor Protocol Number: 10975 Start Date*: 2023-06-21
    Sponsor Name:University Medical Center Groningen
    Full Title: Improving radical resection rates in patients with breast cancer by intraoperative imaging using bevacizumab-IRDye800CW – the MARGIN-2 study
    Medical condition: Female breast cancer patients with small tumor size in which breast conserving therapy is advised by the multidisciplinary tumor board.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001731-31 Sponsor Protocol Number: YFV_001 Start Date*: 2019-09-02
    Sponsor Name:Aarhus University Hospital
    Full Title: Cytotoxicity of Yellow Fever specific CD8 T cells Following YF-17D Vaccination
    Medical condition: Healthy individuals or HIV-1 infected individuals
    Disease: Version SOC Term Classification Code Term Level
    22.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003284-21 Sponsor Protocol Number: 71151 Start Date*: 2020-01-13
    Sponsor Name:Radboudumc
    Full Title: Radio guided lymph node dissection in oligo metastatic prostate cancer patients; a feasibility study
    Medical condition: Patients diagnosed with prostate cancer upon prostate biopsy, who are suspected of having lymph node involvement based upon PSMA-PET/CT.
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001775-20 Sponsor Protocol Number: CHDR1644 Start Date*: 2018-07-12
    Sponsor Name:Centre for Human Drug Research
    Full Title: Immunomonitoring of tacrolimus in healthy volunteers
    Medical condition: Immunesuppression
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2020-003474-45 Sponsor Protocol Number: 74742 Start Date*: 2023-02-17
    Sponsor Name:Erasmus University Medical Center
    Full Title: The STELLAR trial: Fluorescence-guided surgery in laryngeal- and hypopharyngeal cancer: a feasibility trial
    Medical condition: Squamous cell carcinoma of the larynx and hypoharynx
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-004217-14 Sponsor Protocol Number: P21.128 Start Date*: 2022-11-09
    Sponsor Name:Leiden University Medical Center
    Full Title: FLUOPANC-trial - Intraoperative near-infrared fluorescence imaging in pancreatic- and extrahepatic bile duct tumors using cRGD-ZW800-1 and dedicated imaging systems: A phase II feasibility, dose-ra...
    Medical condition: Pancreatic cancer (pancreatic carcinoma) Extrahepatic bile duct cancer (cholangiocarcinoma)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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