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Clinical trials for Exfoliation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    16 result(s) found for: Exfoliation. Displaying page 1 of 1.
    EudraCT Number: 2012-001247-51 Sponsor Protocol Number: v.1/040312 Start Date*: 2012-06-04
    Sponsor Name:Mika Harju
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10006028 Borderline glaucoma (glaucoma suspect) LLT
    14.1 10015919 - Eye disorders 10037118 Pseudoexfoliation glaucoma LLT
    14.1 10015919 - Eye disorders 10036675 Primary angle-closure glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2019-004841-34 Sponsor Protocol Number: 101219 Start Date*: 2020-08-24
    Sponsor Name:Mika Harju
    Full Title: Selective laser trabeculoplasty versus eye drops for first line treatment of exfoliation ocular hypertension or glaucoma: a randomised clinical trial
    Medical condition: Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-004212-31 Sponsor Protocol Number: CM-05-10 Start Date*: 2007-12-20
    Sponsor Name:Alcon Laboratories, Inc.
    Full Title: A Double-Masked, Multiple-Dose, Study of the IOP-Lowering Efficacy of Brinzolamide 1.0% Compared to Placebo When Added to Travoprost 0.004%/Timolol 0.5% Fixed Combination as Adjunctive Therapy in P...
    Medical condition: primary open-angle glaucoma exfoliation glaucoma pigmentary glaucoma ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10035015 Pigmentary glaucoma PT
    9.1 10030043 Ocular hypertension LLT
    9.1 10037118 Pseudoexfoliation glaucoma LLT
    9.1 10036719 Primary open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2013-002895-42 Sponsor Protocol Number: GITS2013_4.0 Start Date*: 2013-10-10
    Sponsor Name:Region Västerbotten
    Full Title: Glaucoma Intensity Treatment Study – Intensive non-invasive glaucoma treatment vs conventional stepwise treatment – a prospective, randomized phase IV study of disease progression in glaucoma (GITS...
    Medical condition: Glaucoma, open-angle and PEX glaucoma.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10030856 Open-angle glaucoma LLT
    20.0 100000004853 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-004023-38 Sponsor Protocol Number: GLC0107 Start Date*: 2007-07-30
    Sponsor Name:IRCCS- FONDAZIONE G.B. BIETTI PER LO STUDIO E LA RICERCA IN OFTALMOLOGIA-ONLUS
    Full Title: Prospective, multicentric, double-masked clinical study to compare the efficacy and safety of Ganfort and Duotrav in primary open angle and pseudoexfoliative glaucoma patients previously treated wi...
    Medical condition: Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018304 Glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-022984-36 Sponsor Protocol Number: 201051 Start Date*: Information not available in EudraCT
    Sponsor Name:Santen Oy
    Full Title: A phase III, randomized, double-masked 6-month clinical study to compare the efficacy and safety of the preservative-free fixed dose combination of tafluprost 0.0015% and timolol 0.5% eye drops to ...
    Medical condition: Patients diagnosed with ocular hypertension or open-angle glaucoma (primary open-angle glaucoma [POAG], capsular glaucoma or pigmentary glaucoma).
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030043 Ocular hypertension LLT
    12.1 10036719 Primary open angle glaucoma LLT
    12.1 10035015 Pigmentary glaucoma LLT
    12.1 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) CZ (Completed) ES (Completed) PT (Completed) AT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2010-022965-82 Sponsor Protocol Number: 201050 Start Date*: 2010-12-22
    Sponsor Name:Santen Oy
    Full Title: A phase III, randomized, double-masked 6-month clinical study to compare the efficacy and safety of the preservative-free fixed-dose combination of tafluprost 0.0015% and timolol 0.5% eye drops to ...
    Medical condition: Ocular hypertension and POAG, capsular glaucoma and pigmentary glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10035015 Pigmentary glaucoma PT
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    14.1 10015919 - Eye disorders 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) DE (Completed) EE (Completed) NL (Completed) PL (Completed) IT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000404-10 Sponsor Protocol Number: HCSC-BIMATOPROSTUD-13 Start Date*: 2015-06-10
    Sponsor Name:Hospital Clinico San Carlos
    Full Title: Effectiveness, tolerability and impact in the ocular surface of Bimatoprost and Tafluprost pods in patients with glaucoma and ocular hypertension
    Medical condition: Glaucoma andr ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004060-24 Sponsor Protocol Number: Glaucoma Xalacam /Combigan Start Date*: 2005-11-24
    Sponsor Name:Department of Clinical Pharmacology
    Full Title: A double-masked randomized cross-over study comparing the effect of Xalacom (latanoprost/timolol) and Combigan (brimonidine/timolol) fixed combination on intraocular pressure and ocular blood flow ...
    Medical condition: Glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-004972-74 Sponsor Protocol Number: 20160227 Start Date*: 2020-09-15
    Sponsor Name:Amgen Inc.
    Full Title: An Open-label, Ascending Multiple dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Romosozumab in Children and Adolescents With Osteogenesis Imperfecta
    Medical condition: Osteogenesis imperfecta (OI) is a group of genetic skeletal disorders characterized by increased bone fragility, low bone mass , and increased bone turnover contributing to osteoporosis, fracture...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10031243 Osteogenesis imperfecta PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) GR (Completed) IT (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-000184-40 Sponsor Protocol Number: 20130173 Start Date*: 2014-09-11
    Sponsor Name:Amgen, Inc.
    Full Title: Prospective, Multicenter, Single-arm Study to Evaluate Efficacy, Safety, and Pharmacokinetics of Denosumab in Children With Osteogenesis Imperfecta
    Medical condition: Osteogenesis Imperfecta
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10031243 Osteogenesis imperfecta PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Completed) GB (GB - no longer in EU/EEA) HU (Completed) ES (Completed) Outside EU/EEA BG (Completed) PL (Prematurely Ended) BE (Completed) FR (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-005244-17 Sponsor Protocol Number: GED-0507-ACN-01-14 Start Date*: 2015-09-28
    Sponsor Name:PPM SERVICES S.A.
    Full Title: AN OPEN LABEL CLINICAL STUDY TO EVALUATE THE LONG-TERM DERMAL SAFETY PROFILE OF 12-WEEKS TOPICAL ADMINISTRATION OF TWO DIFFERENT DOSES OF N-ACETYL-GED-0507-34-LEVO GEL IN PATIENTS WITH MILD TO MODE...
    Medical condition: Acne vulgaris
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10000519 Acne vulgaris LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002601-30 Sponsor Protocol Number: QTM/OMN0111 Start Date*: 2011-09-26
    Sponsor Name:OMNIVISION GmbH
    Full Title: A COMPARISON OF LATANOPROST 50µg/ml EYE DROPS vs. XALATAN EYE DROPS IN THE TREATMENT OF OPEN ANGLE GLAUCOMA: AN OPEN, RANDOMIZED, CLINICAL TRIAL
    Medical condition: Open angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2015-005540-34 Sponsor Protocol Number: CLR_14_12 Start Date*: 2016-07-19
    Sponsor Name:Sun Pharma Advanced Research Company, Ltd. (SPARC)
    Full Title: A Multi-Center, Investigator-Masked, Randomized, Crossover, Equivalence Study of the Safety and Efficacy of Once Daily Brimonidine Tartrate 0.35% Ophthalmic Suspension Compared with Brimonidine Tar...
    Medical condition: Open-angle glaucoma, chronic angle closure glaucoma with patent iridotomy, pseudoexfoliation, pigment dispersion, or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    19.1 10015919 - Eye disorders 10018304 Glaucoma PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2014-005273-37 Sponsor Protocol Number: 201450 Start Date*: 2015-02-17
    Sponsor Name:Santen Oy
    Full Title: A phase IV study on the changes in ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switched from Ganfort® eye drops (bimatoprost 0.03%/timolol 0.5%) to Taptiq...
    Medical condition: Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    17.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    17.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    17.1 10015919 - Eye disorders 10074026 Exfoliation glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003369-14 Sponsor Protocol Number: V00034 CR 309 1B Start Date*: 2006-12-12
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: Efficacy and tolerance of the emollient cream V0034 CR in the symptomatic treatment of ichthyosis in children. International, multicentric, randomised, controlled, double blind study, in parallel g...
    Medical condition: Patients presenting with ichthyosis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10040785 Skin and subcutaneous tissue disorders SOC
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) EE (Completed) CZ (Completed) NL (Completed) DE (Completed) LT (Completed) FR (Completed) LV (Completed) IT (Completed) ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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