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Clinical trials for Eye therapeutic procedures

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44412   clinical trials with a EudraCT protocol, of which   7421   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    28 result(s) found for: Eye therapeutic procedures. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2022-002434-13 Sponsor Protocol Number: 01-INSULINAGLAUCOMA-2022 Start Date*: 2023-01-18
    Sponsor Name:Barbara Burgos-Blasco
    Full Title: RANDOMIZED CLINICAL TRIAL DOUBLE BLIND (WITH BLIND EVALUATOR) TO DETERMINE THE EFFECTIVENESS AND SAFETY OF TOPICAL INSULIN IN THE TREATMENT OF DRY EYE IN PATIENTS WITH TOPICAL HYPOTENSIVE DRUGS
    Medical condition: Dry eye disease in glaucoma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003326-13 Sponsor Protocol Number: BTI-011-EC/15/QUER Start Date*: 2016-01-05
    Sponsor Name:BTI Biotechnology Institute I mas D
    Full Title: Randomized, parallel groups, multicenter and blind to evaluators clinical trial, to evaluate the efficacy and safety of PRGF-Endoret eye drops, in patients with stage 2 and 3 neurotrophic keratitis.
    Medical condition: Neurotrophic Keratitis (NK)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000465-17 Sponsor Protocol Number: CHL.3-02-2019 Start Date*: 2020-06-16
    Sponsor Name:Sintetica S.A.
    Full Title: A Phase II/III, Randomized, Double-Masked, Vehicle-Controlled, Efficacy, Safety and Tolerability Study of Chloroprocaine 3% Gel Eye Drops in healthy volunteers
    Medical condition: healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10024758 Local anaesthesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-015795-10 Sponsor Protocol Number: SMA-09-19-SVN Start Date*: 2009-11-12
    Sponsor Name:Alcon d.o.o.
    Full Title: Assessing the safety and efficacy of switching to Azarga (Brinzolamide/Timolol Fixed Combination), as replacement therapy in patients with uncontrolled intraocular pressure
    Medical condition: uncontrolled intraocular pressure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2005-004464-24 Sponsor Protocol Number: P04608 Start Date*: 2006-04-21
    Sponsor Name:Integrated Therapeutics Group, Inc
    Full Title: A Double-blind, Placebo-controlled, Randomized, Parallel-group Multicenter Study of Mometasone Furoate Nasal Spray on Sleep Disturbances and Daytime Somnolence in Subjects with Symptomatic Seasonal...
    Medical condition: Seasonal Allergic Rhinitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) ES (Completed) GB (Completed) NL (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-015559-25 Sponsor Protocol Number: KCH1724 Start Date*: 2010-04-22
    Sponsor Name:King's College Hospital NHS Foundation Trust
    Full Title: Preoperative intravitreal ranibizumab for persistent diabetic vitreous haemorrhage: A randomized, double-masked, controlled study
    Medical condition: Retinopathy is a well recognised complication of diabetes and is a leading cause of vision loss in this patient group. The severity of diabetic retinopathy varies, but in its most severe form (pro...
    Disease: Version SOC Term Classification Code Term Level
    12. 10047655 Vitreous Haemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005701-43 Sponsor Protocol Number: PROP-001-CP3 Start Date*: 2013-04-11
    Sponsor Name:Fresenius Kabi Deutschland GmbH
    Full Title: Therapeutic Equivalence Study of Propofol Using Target-Controlled Infusion of Propofol 2% (20 mg/mL) MCT Fresenius Compared with Diprivan® 20 mg/mL (AstraZeneca) in Patients Undergoing Elective Sur...
    Medical condition: Elective minor Surgery
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2019-001493-28 Sponsor Protocol Number: OPA1 Start Date*: 2020-09-24
    Sponsor Name:Medizinische Universität Graz, Univ.-Augenklinik
    Full Title: Raxone® treatment for patients with dominant optic atrophy due to OPA1 gene mutation
    Medical condition: Autosomal dominant optic atrophy (ADOA)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10019895 Hereditary optic atrophy PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-001660-30 Sponsor Protocol Number: CHL.3/01-2019/M Start Date*: 2020-06-03
    Sponsor Name:Sintetica S.A.
    Full Title: A prospective, observer-masked, randomized clinical trial to investigate and compare the clinical efficacy of chloroprocaine 3% gel and tetracaine 0.5% eye drop as topical anesthetics in phacoemuls...
    Medical condition: cataract surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10063797 Cataract operation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003277-34 Sponsor Protocol Number: T2380-PIV-017 Start Date*: 2018-01-15
    Sponsor Name:Laboratoires Théa
    Full Title: Phase IV, open-label, randomized clinical trial to evaluate the effects of Fydrane® and standard topical mydriatics and anaesthetics protocol on ocular surface after cataract surgery.
    Medical condition: Cataracts
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10007739 Cataract PT
    20.0 10042613 - Surgical and medical procedures 10063797 Cataract operation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-002527-15 Sponsor Protocol Number: NGF0212 Start Date*: 2013-03-01
    Sponsor Name:Dompé farmaceutici s.p.a
    Full Title: Study Brand Name : REPARO Study full title: An 8-week phase I/II, multicenter, randomized, double-masked, vehicle controlled parallel group study with a 48 or 56 week follow-up period to evaluat...
    Medical condition: Adult patients diagnosed with unilateral stage 2 (persistent epithelial defect) and stage 3 (corneal ulcer) NK refractory to one or more conventional non-surgical treatments. Patients with Controla...
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004853 10032064 Other forms of keratitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) PT (Completed) HU (Completed) ES (Completed) PL (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001823-30 Sponsor Protocol Number: 043/SI Start Date*: 2017-06-12
    Sponsor Name:SIFI SpA
    Full Title: Randomized, Assessor-Masked, Active-Controlled, Phase 3 Study to Evaluate Efficacy, Safety and Tolerability of 0.08% Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Comparison with 0.02% ...
    Medical condition: Acanthamoeba keratitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10069408 Acanthamoeba keratitis PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) PL (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003501-25 Sponsor Protocol Number: PQ-110-003 Start Date*: 2019-02-28
    Sponsor Name:ProQR Therapeutics IV B.V.
    Full Title: A Double-Masked, Randomized, Controlled, Multiple-Dose Study to Evaluate the Efficacy, Safety, Tolerability and Systemic Exposure of QR-110 in Subjects with Leber’s Congenital Amaurosis (LCA) due t...
    Medical condition: Leber’s Congenital Amaurosis (LCA) due to c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10070667 Leber's congenital amaurosis PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) NL (Ongoing) BE (Completed) FR (Ongoing) GB (GB - no longer in EU/EEA) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-003164-50 Sponsor Protocol Number: CEUSUM Start Date*: 2012-10-19
    Sponsor Name:OSPEDALE S. RAFFAELE DI MILANO
    Full Title: CONTRAST ENHANCED ULTRASOUND (CEUS) IN UVEAL MELANOMA: QUANTITATIVE ASSESSMENT OF TUMOR RESPONSE TO GAMMA KNIFE RADIOSURGERY (GKR)
    Medical condition: patients affected by uveal melanoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061252 Intraocular melanoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-005565-40 Sponsor Protocol Number: OTP-B-Linköping Start Date*: 2014-09-11
    Sponsor Name:Department of Biomedical Engineering, Linköping University
    Full Title: Optical measurement with 5-ALA during surgical resection of brain tumors in children
    Medical condition: Tumour border by means of fluorescenstechnique during surgical resection of brain tumours.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2019-002411-26 Sponsor Protocol Number: GO-SLEEP Start Date*: 2019-10-09
    Sponsor Name:CHU de Poitiers
    Full Title: Impact of Gamma-OH on sleep in ICU patients difficult to wean from mechanical ventilation
    Medical condition: Patients difficult to wean from mechanical ventilation in the ICU
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10067221 Mechanical ventilation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003237-25 Sponsor Protocol Number: POPPIV4.022.07.16 Start Date*: 2015-08-21
    Sponsor Name:University of Oxford
    Full Title: A blinded randomised placebo-controlled trial investigating the efficacy of morphine analgesia for procedural pain in infants
    Medical condition: Screening for Retinopathy of Prematurity is an essential yet painful routine test that is performed multiple times in infants who are born prematurely. Premature infants also regularly require heel...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000867-25 Sponsor Protocol Number: OMS302-ILR-004 Start Date*: 2012-07-23
    Sponsor Name:Omeros Corporation
    Full Title: A Phase 3 Randomised, Double-Masked, Placebo-Controlled Study of the Pharmacokinetics of OMS302 and the Effect of OMS302 on Intraoperative Pupil Diameter and Early Postoperative Pain in Subjects Un...
    Medical condition: Intraocular Lens Replacement with Pharmacoemulsification
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004865 10054771 Intraocular lens replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-024328-53 Sponsor Protocol Number: HULPOFT-2010-01 Start Date*: 2012-05-14
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital Universitario La Paz
    Full Title: Phase IIa clinical trial to determine the feasibility and safety of using autologous expanded stem cell (ASC) from fat in the treatment of keratopathy associated with bilateral limbic insufficiency
    Medical condition: Keratopathy associated with bilateral limbic insufficiency.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-003885-15 Sponsor Protocol Number: OMS302-ILR-006 Start Date*: 2014-01-06
    Sponsor Name:Omeros Corporation
    Full Title: A Phase 3 Randomised, Double-Masked, Placebo-Controlled Study of the Effect of OMS302 on Intraoperative Pupil Diameter in Subjects at High Risk of Intraoperative Floppy Iris Syndrome Undergoing Int...
    Medical condition: Intraocular Lens Replacement (ILR) in subject at high risk for Intraoperative Floppy Iris Syndrome (IFIS)
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10054771 Intraocular lens replacement LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Prematurely Ended) AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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