Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Pain out of proportion

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    164 result(s) found for: Pain out of proportion. Displaying page 1 of 9.
    1  2  3  4  5  6  7  8  9  Next»
    EudraCT Number: 2008-006176-30 Sponsor Protocol Number: NW-1029/01-08 Start Date*: 2009-03-13
    Sponsor Name:Newron Pharmaceuticals S.p.A.
    Full Title: EFFICACY AND SAFETY OF TWO FIXED DOSES (160 OR 320 MG/DAY) OF RALFINAMIDE IN PATIENTS WITH CHRONIC NEUROPATHIC LOW BACK PAIN. A MULTICENTER, DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED 12- WEEK ST...
    Medical condition: Chronic neuropathic low back pain.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended) DE (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006184-70 Sponsor Protocol Number: PM07/8404 Start Date*: 2009-01-09
    Sponsor Name:The Leeds Teaching Hospitals NHS Trust
    Full Title: A POPULATION STUDY INTO THE PREVALENCE AND GENETIC PROFILE OF PATIENTS WITH CHRONIC PAIN WHO DO NOT RESPOND TO ORAL CODEINE A single site, pilot population study into the prevalence and genetic p...
    Medical condition: Chronic pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-001392-17 Sponsor Protocol Number: 19636 Start Date*: 2022-01-03
    Sponsor Name:Bayer AG
    Full Title: A randomized, double-blind, cross-over, placebo-controlled, multi-center, Phase 2a study to assess the safety and efficacy of BAY 2395840 in patients with diabetic neuropathic pain.
    Medical condition: Neuropathic pain associated with diabetic peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10067547 Diabetic peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) ES (Completed) SK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-004584-11 Sponsor Protocol Number: 10140021910007 Start Date*: 2021-02-03
    Sponsor Name:Maxima MC
    Full Title: Optimal postoperative Pain management After Lung surgery (OPtriAL): multi-centre randomised trial
    Medical condition: Acute postoperative pain after lung surgery
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000107-36 Sponsor Protocol Number: VER-CLBP-001 Start Date*: 2021-03-24
    Sponsor Name:Vertanical GmbH
    Full Title: Proof of efficacy, maintenance of efficacy, long-term safety and investigation of the potential for dependence and abuse and the effect of abrupt drug withdrawal of VER-01 in a multicenter study in...
    Medical condition: For the treatment of patients with chronic non-specific low back pain when drug treatment is indicated and previous optimised treatments with non-opioid analgesics have not led to sufficient pain r...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002066-14 Sponsor Protocol Number: 20887 Start Date*: 2020-12-30
    Sponsor Name:Bayer AG
    Full Title: A randomized, placebo-controlled, double-blind, parallel-group, multicenter combined Phase 2a/2b study to assess the efficacy and safety of BAY 1817080 in patients with diabetic neuropathic pain
    Medical condition: Neuropathic pain associated with diabetic peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10067547 Diabetic peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) NO (Completed) CZ (Completed) FI (Completed) SE (Completed) HU (Prematurely Ended) SK (Prematurely Ended) DK (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004539-54 Sponsor Protocol Number: TMP-0731-2018 Start Date*: 2019-06-03
    Sponsor Name:Fraunhofer-Institute for Translational Medicine and Pharmacology ITMP
    Full Title: Capability of Tofacitinib or Etanercept to accelerate clinical relevant tapering of non-steroidal anti-inflammatory drugs and treat-to-target guided de-escalation of corticosteroids in patients wit...
    Medical condition: Patients with active Rheumatoid Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001316-35 Sponsor Protocol Number: KF6005/07 Start Date*: 2012-12-20
    Sponsor Name:Grünenthal GmbH
    Full Title: Efficacy, safety, and tolerability of oral Cebranopadol versus morphine sulphate PR in subjects with chronic moderate to severe pain related to cancer.
    Medical condition: The trial population, comprising patients with cancer pain requiring WHO Step III analgesics, will represent the typical population suffering from cancer-related pain. Patient having various types ...
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed) DE (Prematurely Ended) HU (Completed) SE (Completed) ES (Completed) SK (Completed) PL (Completed) NL (Completed) AT (Completed) DK (Completed) BG (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2019-000848-95 Sponsor Protocol Number: 020119 Start Date*: 2019-07-29
    Sponsor Name:Dansk Hovedpine Center, Neurologisk Klinik, Rigshospitalet - Glostrup
    Full Title: A Placebo-Controlled, Double-Blind, Randomized, Proof-of-Concept Study to Evaluate the Efficacy and Tolerability of Erenumab in Patients with Trigeminal Neuralgia
    Medical condition: Trigeminal neuralgia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10044652 Trigeminal neuralgia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004269-96 Sponsor Protocol Number: IG8801CLBP201 Start Date*: 2016-02-24
    Sponsor Name:Gador S.A.
    Full Title: A 24 weeks multicentre, randomized, double-blind, placebo-controlled, parallel group, study to evaluate the efficacy, safety and tolerability of intravenous IG-8801 20 mg and 40 mg in subjects with...
    Medical condition: non-specific Chronic Low Back Pain persisting for at least 3 months
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10008837 Chronic back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002130-20 Sponsor Protocol Number: 1.4 Start Date*: 2020-02-07
    Sponsor Name:Norfolk and Norwich University Hospitals NHS Foundation Trust
    Full Title: Research on Efficacy of Teriparatide use in the Return of recruits to Normal duty.
    Medical condition: Healthy individuals with stress fractures.
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10042212 Stress fracture PT
    20.1 10022117 - Injury, poisoning and procedural complications 10042212 Stress fracture PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-001600-11 Sponsor Protocol Number: MP4CO-13-SCD-206 Start Date*: 2013-09-25
    Sponsor Name:Sangart, Inc.
    Full Title: A Phase 2 Multi-center, Randomized, Double-blind, Comparator-Controlled Dose Finding Study to Evaluate MP4CO for the Acute Treatment of Vaso-occlusive Crises in Subjects with Sickle Cell Disease
    Medical condition: Sickle cell disease (SCD) is an autosomal recessive disorder of the β globin gene of the hemoglobin molecule. One single point mutation results in a lifetime of chronic morbidity and mortality. Vas...
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-020324-22 Sponsor Protocol Number: CC-10004-PSA-005 Start Date*: 2011-03-07
    Sponsor Name:Celgene Corporation
    Full Title: A Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-group, efficacy and safety study of two doses of Apremilast (CC-10004) in subjects with active psoriatic arthritis who...
    Medical condition: Psoriatic arthritis, an inflammatory arthritis that occurs in 6 to 39% of patients with psoriasis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) BE (Completed) CZ (Completed) LT (Completed) IT (Completed) PL (Completed) BG (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001354-95 Sponsor Protocol Number: 149/11 Start Date*: 2013-06-13
    Sponsor Name:Keele University
    Full Title: A randomised, multi-centre, open-label, active-comparator, pragmatic clinical trial of low-dose colchicine versus naproxen in patients with acute gout.
    Medical condition: Acute Gout
    Disease: Version SOC Term Classification Code Term Level
    16.0 10027433 - Metabolism and nutrition disorders 10018627 Gout PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-005329-11 Sponsor Protocol Number: FX006-2014-008 Start Date*: 2015-02-26
    Sponsor Name:Flexion Therapeutics
    Full Title: A Double-Blind, Randomized, Single-Dose Study to Assess the Safety and Efficacy of FX006 for the Treatment of Pain in Patients with Osteoarthritis of the Knee
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) LT (Completed) EE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018386-32 Sponsor Protocol Number: CC-10004-PSA-003 Start Date*: 2010-12-27
    Sponsor Name:Celgene Corporation
    Full Title: A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, EFFICACY AND SAFETY STUDY OF TWO DOSES OF APREMILAST (CC-10004) IN SUBJECTS WITH ACTIVE PSORIATIC ARTHRITIS
    Medical condition: Psoriatic arthritis, an inflammatory arthritis that occurs in 6-39% of psoriasis patients
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) EE (Completed) GB (Completed) BE (Completed) DE (Completed) HU (Completed) ES (Completed) IT (Completed) PL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2018-001301-90 Sponsor Protocol Number: SNFCT2017-06 Start Date*: 2020-05-20
    Sponsor Name:Sanifit Therapeutics S.A
    Full Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of SNF472 When added to Background Care for the Treatment of Calciphylaxis.
    Medical condition: Calciphylaxis (Calcific uremic arteriolopathy [CUA])
    Disease: Version SOC Term Classification Code Term Level
    21.0 10027433 - Metabolism and nutrition disorders 10051714 Calciphylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) ES (Prematurely Ended) PL (Completed) BE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-000311-34 Sponsor Protocol Number: P07642 Start Date*: 2011-11-29
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Effect of Golimumab Administered Subcutaneously in Subjects with Active Axial Spondyloarthritis (Phase 3b, Protocol No. P0...
    Medical condition: Active Axial Spondyloarthritis (SpA)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10041672 Spondylitis ankylosing LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) FI (Completed) IT (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2013-001701-85 Sponsor Protocol Number: AKT-001 Start Date*: 2013-10-18
    Sponsor Name:Akron Molecules GmbH
    Full Title: A placebo controlled, double blind, randomised, 8-week phase IIa proof of concept study to assess the efficacy and safety of AKR 202 in patients with osteoarthritis pain.
    Medical condition: Moderate to severe osteoarthritis pain in the index knee
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Completed) DE (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2008-001841-24 Sponsor Protocol Number: C25608/4027/BP/EU Start Date*: 2008-08-04
    Sponsor Name:Cephalon France
    Full Title: A European Multicenter Open-label Study of Breakthrough Cancer Pain: Assessment of Fentanyl Buccal Tablets Titration and Treatment in Opioid-Tolerant Patients
    Medical condition: Breakthrough Pain (BTP) in cancer patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064556 Breakthrough pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) NL (Completed) FR (Completed) IE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  7  8  9  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Thu May 29 01:38:22 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA