Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Partial Seizure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    198 result(s) found for: Partial Seizure. Displaying page 1 of 10.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-016996-31 Sponsor Protocol Number: P09-004 Start Date*: 2010-06-28
    Sponsor Name:Upsher-Smith Laboratories, Inc.
    Full Title: A Randomized, Multicenter, Double-Blind, Placebo–Controlled, Parallel-Group, Phase 3 Study to Evaluate the Efficacy and Safety of USL255 as Adjunctive Therapy in Patients with Refractory Partial-O...
    Medical condition: Refractory partial-onset seizures with or without secondary generalization
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10056209 Partial seizures with secondary generalisation PT
    14.0 10029205 - Nervous system disorders 10034090 Partial seizures, complex LLT
    14.0 10029205 - Nervous system disorders 10040703 Simple partial seizures PT
    14.0 10029205 - Nervous system disorders 10048674 Partial seizures with secondary generalization LLT
    14.0 10029205 - Nervous system disorders 10010145 Complex partial seizures PT
    14.0 10029205 - Nervous system disorders 10034091 Partial seizures, simple LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) ES (Completed) GR (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001982-33 Sponsor Protocol Number: E2090-E044-401 Start Date*: 2005-09-05
    Sponsor Name:Eisai Limited
    Full Title: An open label study of Zonegran (zonisamide) in patients with partial onset seizures.
    Medical condition: Indicated as adjunctive therapy in the treatment of adult patients with partial seizures, with or without secondary generalisation.
    Disease: Version SOC Term Classification Code Term Level
    8.0 10061334 pt
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) AT (Completed) SE (Completed) DK (Completed) FI (Completed) DE (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005440-25 Sponsor Protocol Number: SP904 Start Date*: 2009-02-16
    Sponsor Name:UCB BIOSCIENCES, Inc.
    Full Title: A Multicenter, Open-label Extension Trial to Assess the Long-term Use of Lacosamide Monotherapy and Safety of Lacosamide Monotherapy and Adjunctive Therapy in Subjects with Partial-onset Seizures
    Medical condition: Partial-onset seizures (with and without secondary generalization)
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029205 - Nervous system disorders 10010145 Complex partial seizures PT
    16.1 10029205 - Nervous system disorders 10040703 Simple partial seizures PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IE (Completed) ES (Completed) AT (Completed) DK (Completed) PT (Not Authorised) IT (Completed) FR (Completed) DE (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-005439-27 Sponsor Protocol Number: SP902 Start Date*: 2009-02-16
    Sponsor Name:UCB BIOSCIENCES, Inc.
    Full Title: A Historical-controlled, Multicenter, Double-blind, Randomized Trial to Assess the Efficacy and Safety of Conversion to Lacosamide 400mg/day Monotherapy in Subjects with Partial-onset Seizures
    Medical condition: Partial-onset seizures (with or without secondary generalization)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10040703 Simple partial seizures PT
    14.0 10029205 - Nervous system disorders 10010145 Complex partial seizures PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IE (Completed) ES (Completed) AT (Completed) DK (Completed) PT (Not Authorised) IT (Completed) FR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000152-16 Sponsor Protocol Number: SP774 Start Date*: 2004-10-13
    Sponsor Name:SCHWARZ BIOSCIENCES GmbH; A member of the UCB group
    Full Title: An international open-label extension trial to determine safety and efficacy of long-term oral SPM 927 in patients with partial seizures
    Medical condition: Partial seizures
    Disease: Version SOC Term Classification Code Term Level
    6.0 10034089 LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) HU (Completed) CZ (Completed) FI (Completed) SE (Completed) ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-004586-84 Sponsor Protocol Number: N01364 Start Date*: 2015-11-12
    Sponsor Name:UCB Pharma SA
    Full Title: A multicenter, open-label, randomized, parallel-group, active-controlled study comparing the efficacy and safety of Levetiracetam to Carbamazepine used as monotherapy in subjects (≥16 years) newly ...
    Medical condition: Epilepsy Partial Seizures
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    18.1 10029205 - Nervous system disorders 10061334 Partial seizures PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2019-001205-25 Sponsor Protocol Number: EP0085 Start Date*: 2025-04-25
    Sponsor Name:UCB Biopharma SRL
    Full Title: An Open-Label, Multicenter, Follow-up Study to Evaluate the Long-Term Safety and Efficacy of Brivaracetam Used as Adjunctive Treatment in Subjects >=16 Years of Age With Partial Seizures With or Wi...
    Medical condition: Epilepsy (partial seizures with or without secondary generalization)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2015-004465-87 Sponsor Protocol Number: CTRI476BRU02 Start Date*: 2016-05-04
    Sponsor Name:Novartis Pharmaceuticals
    Full Title: A 24-week Prospective Open-label Multicenter Study to Evaluate the Effect on Seizure Frequency, Safety and Tolerability of Oxcarbazepine Monotherapy in Children With Partial Seizures
    Medical condition: Epilepsy, Partial Seizures
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    19.0 10029205 - Nervous system disorders 10061334 Partial seizures PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2009-017904-95 Sponsor Protocol Number: P09-005 Start Date*: 2010-06-28
    Sponsor Name:Upsher-Smith Laboratories, Inc.
    Full Title: Open-Label Extension Study to Evaluate the Safety of USL255 as Adjunctive Therapy in Patients with Refractory Partial-Onset Seizures who had Participated in P09-004, a Randomized, Multicenter, Doub...
    Medical condition: Refractory partial-onset seizures with or without secondary generalization
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10056209 Partial seizures with secondary generalisation PT
    14.0 10029205 - Nervous system disorders 10034090 Partial seizures, complex LLT
    14.0 10029205 - Nervous system disorders 10040703 Simple partial seizures PT
    14.0 10029205 - Nervous system disorders 10048674 Partial seizures with secondary generalization LLT
    14.0 10029205 - Nervous system disorders 10010145 Complex partial seizures PT
    14.0 10029205 - Nervous system disorders 10034091 Partial seizures, simple LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) ES (Completed) GR (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005078-55 Sponsor Protocol Number: N01183 Start Date*: Information not available in EudraCT
    Sponsor Name:UCB PHARMA
    Full Title: Named Patient Program with Levetiracetam Oral Solution, for Pediatric Patients suffering from Epilepsy having previously participated in study N01148
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    6.1 10040703 PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004333-57 Sponsor Protocol Number: N01221 Start Date*: 2015-02-10
    Sponsor Name:UCB Japan Co., Ltd.
    Full Title: A Double-blind, Randomized, Placebo-controlled 5 Parallel Groups, Confirmatory Trial on the Efficacy and Safety of Levetiracetam used as add-on Therapy at doses of 0.5 to 3 g/day in Patients From 1...
    Medical condition: Epilepsies Partial
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-002322-22 Sponsor Protocol Number: SP757 Start Date*: 2005-01-12
    Sponsor Name:SCHWARZ BIOSCIENCES Inc.
    Full Title: A multi-center, open-label trial to investigate the safety and tolerability of intravenous SPM 927 as replacement for oral SPM 927 in subjects with partial seizures with or without secondary genera...
    Medical condition: partial seizures with or without secondary generalization
    Disease: Version SOC Term Classification Code Term Level
    6.0 10034089 LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) SE (Completed) DE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2017-001515-36 Sponsor Protocol Number: 200776 Start Date*: 2017-08-11
    Sponsor Name:GlaxoSmithKline K.K.
    Full Title: Valproate dose reduction and its clinical evaluation by introducing lamotrigine in Japanese women with epilepsy – single arm, multicenter, and open-label study
    Medical condition: Partial seizures (including secondary generalized seizures) or tonic-clonic seizures with or without myoclonus but without other generalized seizure type(s)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000038485 10043999 Tonic-clonic epilepsy LLT
    20.0 100000014703 10065336 Partial epilepsy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-002167-16 Sponsor Protocol Number: E2007-G000-311 Start Date*: 2017-01-30
    Sponsor Name:Eisai Limited
    Full Title: An Open-Label, Multicenter Study with an Extension Phase to Evaluate the Safety, Tolerability, and Exposure-Efficacy Relationship of Perampanel Oral Suspension when Administered as an Adjunctive Th...
    Medical condition: Epilepsy : 1) Partial-Onset Seizures (POS) 2) Primary Generalized Tonic-Clonic Seizures (PGTC)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10018101 Generalised tonic-clonic seizures HLT
    19.0 10029205 - Nervous system disorders 10061334 Partial seizures PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) ES (Completed) PL (Completed) BE (Completed) IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2013-003420-37 Sponsor Protocol Number: A0081042 Start Date*: 2014-05-16
    Sponsor Name:Pfizer Inc. 235 East 42nd Street, New York, NY 10017
    Full Title: A DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, MULTICENTER STUDY OF THE EFFICACY AND SAFETY OF PREGABALIN AS ADJUNCTIVE THERAPY IN CHILDREN 1 MONTH THROUGH <4 YEARS OF AGE WITH PARTIAL ONSET S...
    Medical condition: Partial onset seizures
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004852 10034089 Partial seizures NOS LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) HU (Completed) NL (Prematurely Ended) ES (Completed) DE (Completed) PL (Completed) SK (Completed) GR (Completed) PT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2021-001433-39 Sponsor Protocol Number: NBI-921352-FOS2021 Start Date*: 2021-09-08
    Sponsor Name:Neurocrine Biosciences, Inc.
    Full Title: A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study to Investigate Safety, Tolerability, Pharmacokinetics, and Efficacy of NBI-921352 as Adjunctive Therapy in Adult Subjects ...
    Medical condition: Focal Onset Seizures (FOS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10016843 Focal seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed) FR (Completed) IT (Completed) BE (Completed) ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2014-002713-32 Sponsor Protocol Number: N01367 Start Date*: 2015-03-11
    Sponsor Name:Korea UCB Co. Ltd.
    Full Title: A Multi-Center, Open-label, Randomized Study to Evaluate the Long Term Effectiveness of Levetiracetam as Monotherapy in Comparison With Oxcarbazepine in Subjects With Newly or Recently Diagnosed Pa...
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2021-004265-12 Sponsor Protocol Number: NBI-921352-FOS2022 Start Date*: 2021-12-21
    Sponsor Name:Neurocrine Biosciences, Inc.
    Full Title: Prospective, Long-Term, Interventional, Active Extension Study to Evaluate the Safety and Tolerability of NBI-921352 as Adjunctive Therapy in Subjects with Focal Onset Seizures (FOS)
    Medical condition: Focal Onset Seizures (FOS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10016843 Focal seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) FR (Completed) HU (Prematurely Ended) ES (Ongoing) IT (Prematurely Ended) BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001318-32 Sponsor Protocol Number: P261-401 Start Date*: 2011-11-17
    Sponsor Name:Upsher-Smith Laboratories, Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Intranasal Midazolam (USL261) in the Outpatient Treatment of Subjects with Seizure Clusters ARTEMIS-1: Acute Rescu...
    Medical condition: epilepsy
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10015052 Epileptic seizure LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) DE (Prematurely Ended) IT (Prematurely Ended) HU (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-001887-55 Sponsor Protocol Number: SCO/BIA-2093-305 Start Date*: 2007-10-12
    Sponsor Name:BIAL - Portela & Ca, S.A.
    Full Title: Efficacy and safety of eslicarbazepine acetate (BIA 2-093) as adjunctive therapy for refractory partial seizures in children: a double-blind, randomised, placebo-controlled, parallel-group, multice...
    Medical condition: children and adolescents with refractory partial epileptic seizures
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: PT (Completed) HU (Completed) CZ (Completed) AT (Completed) FR (Completed) SK (Completed) IT (Completed) ES (Completed) GB (Completed) DE (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Mon Feb 09 07:27:16 CET 2026 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA