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Clinical trials for Quality adjusted life year

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    151 result(s) found for: Quality adjusted life year. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2020-005523-37 Sponsor Protocol Number: BromCO Start Date*: 2021-06-21
    Sponsor Name:URSAPHARM Arzneimittel GmbH
    Full Title: A prospective controlled proof-of-concept trial to demonstrate anti-viral effects of oral bromelaine in COVID-19 positive patients
    Medical condition: Diagnosis of SARS-CoV-2 infection documented by a positive PCR test
    Disease: Version SOC Term Classification Code Term Level
    23.1 10042613 - Surgical and medical procedures 10084460 COVID-19 treatment PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001452-30 Sponsor Protocol Number: 010815testis Start Date*: 2015-12-07
    Sponsor Name:Copenhagen University Hospital Rigshospitalet
    Full Title: A Randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig Cell Insufficiency (Einstein-intervention)
    Medical condition: Leydig Cell dysfunction
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004860 10067734 Testosterone deficiency LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-004012-10 Sponsor Protocol Number: MODIFI Start Date*: 2021-06-17
    Sponsor Name:UZ Leuven
    Full Title: Model-informed infliximab dose de-escalation following earlier dose escalation in adult patients with inflammatory bowel diseases
    Medical condition: Inflammatory bowel diseases - Crohn's disease - ulcerative colitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001312-30 Sponsor Protocol Number: Start Date*: 2019-04-30
    Sponsor Name:Common Services Agency
    Full Title: SPRING - Seizure PRophylaxis IN Glioma
    Medical condition: Seizures in patients with suspected cerebral glioma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10018338 Glioma PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061030 Brain tumour LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2021-001840-83 Sponsor Protocol Number: SAGA Start Date*: 2022-04-26
    Sponsor Name:University Medical Center Utrecht
    Full Title: Short-course aminoglycosides as adjunctive treatment in adults with sepsis
    Medical condition: Patients admitted with sepsis of unknown origin, suspected urinary origin or suspected abdominal origin
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-003068-47 Sponsor Protocol Number: UROBOTOX 1 Start Date*: 2005-09-22
    Sponsor Name:Region Skåne, Universitetssjukhuset i Lund, Urologiska kliniken
    Full Title: Behandling med botulinumtoxin vid neurogen blåsfunktionsstörning
    Medical condition: The trial addresses patients with severe symptoms of neurogenic detrusor overactivity (urgency and/or urge incontinence). Eligible are those patients who have failed conservative treatment such as ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002214-17 Sponsor Protocol Number: NL78220.029.21 Start Date*: 2023-04-24
    Sponsor Name:Amsterdam University Medical Centers
    Full Title: COLLISION RELAPSE trial - Recurrent colorectal liver metastases: repeat local treatment +/- neoadjuvantsystemic therapy - a phase III prospective randomized controlled trial
    Medical condition: Recurrent colorectal liver metastases
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10024700 Liver metastases LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-005066-36 Sponsor Protocol Number: 12-17 Start Date*: 2013-05-15
    Sponsor Name:VU University Medical Center
    Full Title: Effect of Growth Hormone replacement therapy on cardiovascular risk factors in adult patients with severe growth hormone deficiency: association with IGF-I concentration
    Medical condition: Growth hormone deficiency
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011999-30 Sponsor Protocol Number: VO64.08 Start Date*: 2009-09-16
    Sponsor Name:Stallergenes S.A.
    Full Title: A randomised, double-blind, placebo-controlled, multi-national, Phase III trial to assess the efficacy and safety of 300 IR sublingual immunotherapy (SLIT) administered as allergen-based tablets on...
    Medical condition: House Dust Mite Allergic Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004855 10001723 Allergic rhinitis LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Prematurely Ended) ES (Prematurely Ended) HU (Completed) DE (Prematurely Ended) FR (Completed) DK (Prematurely Ended) SK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-003099-10 Sponsor Protocol Number: DCR-PHXC-301 Start Date*: 2019-06-12
    Sponsor Name:Dicerna Pharmaceuticals Inc
    Full Title: An Open-Label Roll-Over Study to Evaluate the Long-Term Safety and Efficacy of DCR PHXC Solution for Injection (subcutaneous use) in Patients with Primary Hyperoxaluria
    Medical condition: Primary Hyperoxaluria
    Disease: Version SOC Term Classification Code Term Level
    20.1 10038359 - Renal and urinary disorders 10020703 Hyperoxaluria PT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) GB (GB - no longer in EU/EEA) DE (Trial now transitioned) NL (Trial now transitioned) ES (Ongoing) PL (Completed) IT (Trial now transitioned) RO (Completed) NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-001098-16 Sponsor Protocol Number: MO10/9353 Start Date*: 2011-06-06
    Sponsor Name:University of Leeds
    Full Title: STAR: A Randomised Multi-Stage Phase II/III trial of Sunitinib comparing Temporary cessation with Allowing continuation, at the time of maximal radiological response, in the first-line treatment of...
    Medical condition: Metastatic and/or locally advanced Renal Clear Cell Carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-002779-24 Sponsor Protocol Number: 3.089.17 Start Date*: 2018-06-12
    Sponsor Name:University of Aberdeen [...]
    1. University of Aberdeen
    2. NHS Grampian
    Full Title: A randomised, double-blind placebo controlled trial of the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease.
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10010952 COPD LLT
    20.0 100000004855 10010953 COPD exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-003076-39 Sponsor Protocol Number: ARGX-113-1802 Start Date*: 2020-06-25
    Sponsor Name:argenx BVBA
    Full Title: A Phase 2 Trial to Investigate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult Patients With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
    Medical condition: Chronic Inflammatory Demyelinating Polyneuropathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10077384 Chronic inflammatory demyelinating polyneuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed) HU (Completed) ES (Completed) LV (Completed) CZ (Completed) GB (GB - no longer in EU/EEA) BE (Completed) NL (Completed) BG (Completed) DK (Completed) AT (Completed) IT (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2010-020693-42 Sponsor Protocol Number: VO68.10 Start Date*: 2010-09-07
    Sponsor Name:Stallergenes S.A.
    Full Title: A randomised, double-blind, placebo-controlled, multi-national, Phase IIIb study to assess the sustained clinical effect and safety of sublingual immunotherapy administered as birch pollen extract ...
    Medical condition: Birch pollen allergic Rhinoconjunctivitis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021428 - Immune system disorders 10066093 Birch pollen allergy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) SK (Completed) LV (Completed) FI (Completed) CZ (Completed) EE (Completed) LT (Completed) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000201-23 Sponsor Protocol Number: reflect01 Start Date*: 2013-08-30
    Sponsor Name:St. Antonius Ziekenhuis
    Full Title: A randomised clinical trial evaluating the effect of remifentanil vs fentanyl during cardiac surgery on the incidence of chronic thoracic pain.
    Medical condition: chronic thoracic pain after cardiac surgery via sternotomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-002068-29 Sponsor Protocol Number: 1-09-09-2012 Start Date*: 2012-12-03
    Sponsor Name:Jan Stener Joergensen
    Full Title: Antibiotic Prophylaxis and Intervention for Postpartum Infections following Caesarean Section
    Medical condition: Sub-study 1: women delivering a child by caesarean section Sub-study 2: Women, who are hospitalized at the obstetrical ward for reoperation because of superficial or deep infection or haematoma...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-004069-14 Sponsor Protocol Number: PRODIGE31 Start Date*: 2015-01-22
    Sponsor Name:Fédération Francophone de Cancérologie Digestive (FFCD)
    Full Title: A european, multicentre, phase II/III randomised double-blind, placebo controlled study evaluating lanreotide as maintenance therapy in patients with non-resectable duodeno-pancreatic neuroendocrin...
    Medical condition: Non-resectable duodeno-pancreatic neuroendocrine tumours after first line treatment
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10067517 Pancreatic neuroendocrine tumour PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) IE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-003565-19 Sponsor Protocol Number: DR200088 Start Date*: 2021-04-26
    Sponsor Name:CHRU DE TOURS
    Full Title: Espacement personnalisé des perfusions d’eculizumab basé sur un suivi thérapeutique pharmacologique : évaluation médicoéconomique prospective multicentrique chez les patients en rémission atteints ...
    Medical condition: Patients en rémission atteints d’un syndrome hémolytique et urémique atypique nécessitant un traitement au long cours par eculizumab
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024667-40 Sponsor Protocol Number: PGxSTEMI08 Start Date*: 2019-04-23
    Sponsor Name:St. Antonius Hospital
    Full Title: Cost-effectiveness of CYP2C19 guided treatment with antiplatelet drugs in patients with ST-segment-elevation myocardial infarction undergoing immediate percutaneous coronary intervention with stent...
    Medical condition: ST-segment myocardial infarction (STEMI) followed by immediate percutaneous coronary intervention with stent implantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-003107-35 Sponsor Protocol Number: ARGX-113-1902 Start Date*: 2020-07-15
    Sponsor Name:argenx BVBA
    Full Title: Open-label Extension of the ARGX-113-1802 Trial to Investigate the Long-term Safety, Tolerability, and Efficacy of Efgartigimod PH20 SC in Patients With Chronic Inflammatory Demyelinating Polyneuro...
    Medical condition: Chronic Inflammatory Demyelinating Polyneuropathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10077384 Chronic inflammatory demyelinating polyneuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) CZ (Completed) BE (Trial now transitioned) HU (Completed) PL (Trial now transitioned) GB (GB - no longer in EU/EEA) NL (Trial now transitioned) ES (Trial now transitioned) BG (Trial now transitioned) DK (Trial now transitioned) AT (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned) RO (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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