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Clinical trials for Rest

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    999 result(s) found for: Rest. Displaying page 1 of 50.
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    EudraCT Number: 2006-000697-74 Sponsor Protocol Number: ML20115 Start Date*: 2006-08-07
    Sponsor Name:The BONiFIN study group
    Full Title: A phase II, open label study to establish the safety and efficacy of intravenous loading dose of 3 x Bondronat 6 mg in 3 consecutive days in patients with breast cancer and skeletal metastases expe...
    Medical condition: Treatment of pain in breast cancer patients with bone metastases
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-003526-32 Sponsor Protocol Number: EQI7-16-02 Start Date*: 2018-08-14
    Sponsor Name:Fidia Farmaceutici S.p.A.
    Full Title: Randomised, double blind, parallel-groups, non-inferiority versus Flector® and superiority versus Placebo, Phase III clinical trial with Diclofenac Sodium 140 mg medicated plaster in patients with ...
    Medical condition: Patients with painful and phlogistic (inflammatory response) disease due to acute traumatic events (injury/contusion) of the limbs
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-004102-42 Sponsor Protocol Number: EP-DICLO/2G-01-2015 Start Date*: 2017-06-06
    Sponsor Name:Epifarma S.r.l.
    Full Title: Randomized, multi-center, double-blind, three-armed trial, to evaluate the non-inferiority, efficacy and safety of diclofenac2% gel (Test) versus the originator diclofenac2% gel chosen as Referenc...
    Medical condition: Acute traumatic events (injury/contusion) classified from mild to moderate pain at rest to the joints, muscles, tendons and ligaments
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10022117 Injury, poisoning and procedural complications SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) LV (Completed) LT (Completed) HU (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001779-29 Sponsor Protocol Number: EP-DICLO/G-01-2015 Start Date*: 2016-12-15
    Sponsor Name:Epifarma s.r.l.
    Full Title: Randomized, double-blind, parallel group, placebo-controlled, multicenter clinical trial to evaluate efficacy and safety of diclofenac 1% gel produced by Epifarma s.r.l. (Test) versus the originato...
    Medical condition: Patients with acute painful and flogistic (inflammatory) disease due to acute traumatic events (injury/contusion) of joints, muscles, tendons and ligaments
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001674-25 Sponsor Protocol Number: 1684-H-295 Start Date*: 2012-05-25
    Sponsor Name:Francisco J. González Vílchez
    Full Title: Evaluation of the efficacy of sildenafil on the functional capacity of patients with heart failure with preserved ejection fraction. A randomized, double blind, parallel group and placebo-controlle...
    Medical condition: Heart failure with preserved ejection fraction.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10069211 Diastolic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022736-37 Sponsor Protocol Number: Z7202L02 Start Date*: 2011-02-09
    Sponsor Name:Zambon S.p.A.
    Full Title: Efficacy, tolerability and safety of Z7202, a once daily Diclofenac Diethylamine (DEA) medicated plaster in comparison with Flector®, a twice daily Diclofenac Hydroxyethylpyrrolidine medicated plas...
    Medical condition: Diagnosis of single localized post-traumatic painful condition
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10065016 Post-traumatic pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2012-004545-32 Sponsor Protocol Number: DEX-TRA-04 Start Date*: 2013-02-27
    Sponsor Name:Menarini Ricerche S.p.A.
    Full Title: A randomized, double-blind, placebo and active-controlled, parallel-group study to evaluate the analgesic efficacy and safety of dexketoprofen trometamol and tramadol hydrochloride oral fixed combi...
    Medical condition: Treatment of moderate to severe acute pain following abdominal hysterectomy
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SK (Completed) HU (Completed) ES (Completed) LV (Completed) PL (Completed) LT (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2016-001383-10 Sponsor Protocol Number: 57340 Start Date*: 2016-07-04
    Sponsor Name:Rijnstate ziekenhuis
    Full Title: Evaluating the effect of short term withdrawal of PPI's in patients for reducing stomach wall uptake with 99mTc Sestamibi for myocardial perfusion imaging
    Medical condition: The goal is to acquire knowledge about the impact of the withdrawal of PPI’s, so as to minimize disturbance of the stomach wall in myocardial perfusion imaging. The associated main question is ther...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002823-41 Sponsor Protocol Number: AC-065B302 Start Date*: 2019-06-03
    Sponsor Name:Actelion Pharmaceuticals Ltd
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel-group, group-sequential, adaptive, Phase 3 study with open-label extension period to assess the efficacy and safety of selexipa...
    Medical condition: Chronic Thromboembolic Pulmonary Hypertension, inoperable or persistent/recurrent
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10068739 Chronic thromboembolic pulmonary hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (GB - no longer in EU/EEA) CZ (Prematurely Ended) BE (Completed) NL (Completed) HU (Completed) AT (Completed) BG (Completed) DK (Prematurely Ended) PT (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002293-54 Sponsor Protocol Number: Apex01version6 Start Date*: 2007-11-29
    Sponsor Name:University of Dundee
    Full Title: The APEX Trial: Effects of Allopurinol on Coronary and Peripheral Endothelial Function in Patients with Cardiac Syndrome X
    Medical condition: Patients with cardiac syndrome X (typical anginal-like chest pain and normal coronary arteriograms)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-001918-98 Sponsor Protocol Number: 31052015 Start Date*: 2016-01-12
    Sponsor Name:Vestre Viken HF
    Full Title: RATe control in Atrial Fibrillation II
    Medical condition: Permanent atrial fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015059-26 Sponsor Protocol Number: 510460 Start Date*: 2010-08-19
    Sponsor Name:Actavis GmbH & Co. KG
    Full Title: Efficacy of 12 weeks oral Pentalong® on Exercise Capacity and Quality of Life in Patients With Systolic Heart Failure and Secondary Pulmonary Hypertension Short title: CAESAR Clinical efficacy ...
    Medical condition: Woman and men suffering from heart failure NYHA II-IV and secondary pulmonary hypertension Objectives PVR improvement after a 12 week oral Pentalong® therapy in addition to standard long-term HF...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002580-85 Sponsor Protocol Number: 3d Start Date*: 2005-08-08
    Sponsor Name:Rigshospitalet
    Full Title: Acute haemodynanic effects of Treatment with ACE inhibitores in patients with severe Aortic Stenosis
    Medical condition: Aortic valve stenosis is a reduction of the aortic valve orifice to a degree where emptying of the left ventricule is compromised. The two major causes for aortic valve stenosis is calcific valve d...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003521-34 Sponsor Protocol Number: CHUBX2015/14 Start Date*: 2015-10-09
    Sponsor Name:CHU de Bordeaux
    Full Title: Hypertrophic CARdiomyopathy symptom release by alpha stimulant MIDOdrine
    Medical condition: Hypertrophic cardiomyopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004548-31 Sponsor Protocol Number: DEX-TRA-05 Start Date*: 2013-04-15
    Sponsor Name:Menarini Ricerche S.p.A.
    Full Title: A randomized, double-blind, placebo and active-controlled, parallel-group study to evaluate the analgesic efficacy and safety of dexketoprofen trometamol and tramadol hydrochloride oral fixed combi...
    Medical condition: Treatment of moderate to severe acute pain after elective unilateral total hip arthoplasty
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) ES (Completed) HU (Completed) LV (Completed) LT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2005-004128-38 Sponsor Protocol Number: 123 Start Date*: 2006-02-06
    Sponsor Name:Karolinska University Hospital
    Full Title: Pregabalin for pain reduction in Critical Limb Ischemia
    Medical condition: Peripheral arterial disease - Critical Limb Ischemia (CLI) CLI is the end stage of peripheral arterial disease in the legs and is a onsequence of deteriorating blood flow supply to the lower limbs....
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004792-50 Sponsor Protocol Number: C1502 Start Date*: 2017-08-22
    Sponsor Name:Biologische Heilmittel Heel GmbH
    Full Title: Multi-centre, Double-blind, Randomised, Active- and Placebo-Controlled, Confirmatory Trial to Demonstrate Efficacy and Safety of Traumed® Gel in Patients having Acute Ankle Sprain
    Medical condition: Acute Ankle Sprain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-022558-18 Sponsor Protocol Number: 2010-022558-18 Start Date*: 2010-10-11
    Sponsor Name:AZIENDA OSPEDALIERA DI PADOVA
    Full Title: A pilot trial with clenbuterol in spinal and bulbar muscular atrophy (SBMA).
    Medical condition: spinal and bulbar muscular atrophy (SBMA)
    Disease: Version SOC Term Classification Code Term Level
    15.0 10029205 - Nervous system disorders 10029317 Neuromuscular disorders HLGT
    15.0 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    15.0 10028395 - Musculoskeletal and connective tissue disorders 10047868 Weakness of limbs LLT
    15.0 10038738 - Respiratory, thoracic and mediastinal disorders 10013969 Dyspnoea at rest PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000549-73 Sponsor Protocol Number: MRZ 60201-GL-3001 Start Date*: 2008-05-15
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: A prospective, open-label, international, multicenter trial to investigate the efficacy and safety of NT 201, free of complexing proteins, in the treatment of glabellar frown lines
    Medical condition: Treatment of glabellar frown lines
    Disease: Version SOC Term Classification Code Term Level
    10.1 10052609 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-002862-15 Sponsor Protocol Number: BupivacTons20 Start Date*: 2021-03-03
    Sponsor Name:Nordland Hospital. Bodø. Dep of Surgery
    Full Title: Can topical anaesthesia with bupivacaine reduce pain after tonsillectomy?
    Medical condition: Local pain after tonsillectomy, both at rest and during swallowing. Assessed by self-reporting at 1, 2, 3, 4, 5, 6 hours and 1,2,4 and 6 days after surgery.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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