- Trials with a EudraCT protocol (28)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
28 result(s) found for: Tear break-up time.
Displaying page 1 of 2.
EudraCT Number: 2017-004929-33 | Sponsor Protocol Number: SiccaIkervis | Start Date*: 2018-12-05 |
Sponsor Name:KH Hietzing, Department of Ophthalmology | ||
Full Title: Effect of Ciclosporin eyedrops on ocular symptoms and optical image quality in patients with primary or secondary Sjögren syndrome | ||
Medical condition: primary or secondary Sjögren Syndrome | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: AT (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2018-002578-37 | Sponsor Protocol Number: OPHT-240518 | Start Date*: 2019-04-25 |
Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology | ||
Full Title: The effect of antibiotic eye drops on the nasal microbiome in healthy subjects | ||
Medical condition: healthy volunteers | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: AT (Prematurely Ended) | ||
Trial results: View results |
EudraCT Number: 2020-004978-22 | Sponsor Protocol Number: OPHT-300920 | Start Date*: 2021-01-21 |
Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology | ||
Full Title: Detection of acetylsalicylic acid and omega-3 fatty acids in Schirmers’ test strips using mass spectrometry and correlations with tear film and blood flow parameters in healthy adults: an open-labe... | ||
Medical condition: Healthy subjects | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: AT (Completed) | ||
Trial results: View results |
EudraCT Number: 2015-002507-28 | Sponsor Protocol Number: OPHT-280515 | Start Date*: 2015-07-20 | |||||||||||
Sponsor Name:Medical University of Vienna | |||||||||||||
Full Title: Effect of benzalkonium chloride containing eye drops on the conjunctival bacterial flora of dry eye patients. | |||||||||||||
Medical condition: conjunctival bacterial flora in patients with dry eye syndrome | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: AT (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2015-002508-94 | Sponsor Protocol Number: OPHT-030815 | Start Date*: 2015-10-06 | ||||||||||||||||
Sponsor Name:Medical University of Vienna | ||||||||||||||||||
Full Title: Effect of topical azithromycin on tear film thickness in patients with meibomian gland dysfunction – comparison to oral treatment with doxycycline | ||||||||||||||||||
Medical condition: Meibomian gland dysfunction Dry eye syndrome | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: AT (Prematurely Ended) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2022-002434-13 | Sponsor Protocol Number: 01-INSULINAGLAUCOMA-2022 | Start Date*: 2023-01-18 |
Sponsor Name:Barbara Burgos-Blasco | ||
Full Title: RANDOMIZED CLINICAL TRIAL DOUBLE BLIND (WITH BLIND EVALUATOR) TO DETERMINE THE EFFECTIVENESS AND SAFETY OF TOPICAL INSULIN IN THE TREATMENT OF DRY EYE IN PATIENTS WITH TOPICAL HYPOTENSIVE DRUGS | ||
Medical condition: Dry eye disease in glaucoma | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: ES (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2014-004857-15 | Sponsor Protocol Number: SYL1001_III | Start Date*: 2015-05-07 |
Sponsor Name:Sylentis | ||
Full Title: DOSE-FINDING STUDY TO ASSESS THE SAFETY AND EFFECT OF SYL1001 IN PATIENTS WITH OCULAR PAIN | ||
Medical condition: Patients with eye pain associated to dry eye | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: ES (Completed) EE (Completed) | ||
Trial results: View results |
EudraCT Number: 2013-004271-12 | Sponsor Protocol Number: NGF0213 | Start Date*: 2014-01-17 | |||||||||||
Sponsor Name:Dompé s.p.a | |||||||||||||
Full Title: An open-label study evaluating safety and efficacy of recombinant human nerve growth factor (rhNGF) eye drops at different doses in patients with Dry Eye | |||||||||||||
Medical condition: Dry Eye syndrome is caused by either decreased tear production or increased tear film evaporation. Dry eye is a chronic inflammatory condition of the ocular surface with severe symptoms and visual ... | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: AT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-000747-27 | Sponsor Protocol Number: 049/SI | Start Date*: 2020-09-09 | |||||||||||
Sponsor Name:SOCIETÀ INDUSTRIA FARMACEUTICA ITALIANA (SIFI) SPA | |||||||||||||
Full Title: A Multicenter, Randomized, Double-Masked, Placebo-Controlled Phase II Study to evaluate the Safety and Efficacy of Pro-ocular™ 0.5% and 1% in Patients with Dry Eye Syndrome | |||||||||||||
Medical condition: Dry Eye is a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film and accompanied by ocular symptoms, in which tear film instability, hyperosmolarity... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-001022-34 | Sponsor Protocol Number: AVX012-CT-001 | Start Date*: 2016-10-06 | |||||||||||
Sponsor Name:AVIZOREX PHARMA, S.L. | |||||||||||||
Full Title: A phase I/II, double-blind, placebo-controlled study assessing the safety and efficacy of AVX-012 ophthalmic solution in subjects with mild-to-moderate dry eye syndrome | |||||||||||||
Medical condition: Dry eye syndrome | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-006287-50 | Sponsor Protocol Number: EMAOS | Start Date*: 2015-04-01 | |||||||||||
Sponsor Name:Clínica Universidad de Navarra/Universidad de Navarra | |||||||||||||
Full Title: Phase III comparative clinical trial to evaluate the efficacy of amniotic membrane extract for the treatment of severe dry eye disease, in comparison with autologous serum eyedrops. | |||||||||||||
Medical condition: Severe Dry Eye Disease | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2012-002078-30 | Sponsor Protocol Number: RDG-11-244 | Start Date*: 2012-09-10 | |||||||||||
Sponsor Name:Alcon Research, Ltd. | |||||||||||||
Full Title: Assessing the Efficacy and Tolerability of TRAVATAN® Solution without BAK, containing Polyquad® Preservative (travoprost 0.004%) versus LUMIGAN® 0.01% Solution with BAK (bimatoprost 0.01%) in Trea... | |||||||||||||
Medical condition: Ocular hypertension or Open angle glaucoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SI (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2012-004605-27 | Sponsor Protocol Number: Occhuiosecco | Start Date*: 2012-11-05 | |||||||||||
Sponsor Name:AZIENDA OSPEDALIERA ARCISPEDALE S. MARIA NUOVA | |||||||||||||
Full Title: Study Prospective Randomized Controlled Double-Blind: Comparison of tear substitute (Siccafluid) and Autologous Serum in Dry Eye Disease | |||||||||||||
Medical condition: Dry eye disease | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-002238-35 | Sponsor Protocol Number: 11002X-001 | Start Date*: 2012-10-04 | |||||||||||
Sponsor Name:Allergan Ltd. | |||||||||||||
Full Title: A Multicenter, Double-masked, Randomized Study to Compare the Safety and Efficacy of an Investigational Eye Drop Formulation with OPTIVE™ Unit-Dose for 3 Months in Subjects with Dry Eye Disease | |||||||||||||
Medical condition: Dry Eye Disease | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) BE (Completed) DE (Completed) IT (Completed) ES (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2007-000029-23 | Sponsor Protocol Number: NVG06C103 | Start Date*: 2008-10-16 | |||||||||||
Sponsor Name:Novagali Pharma S.A. | |||||||||||||
Full Title: A Phase III, Multicenter, Randomized, Controlled, Double-Masked Trial of NOVA22007 (Ciclosporin 0.1%) Ophthalmic Cationic Emulsion versus Vehicle in Patients with Moderate to Severe Dry Eye Syndrome | |||||||||||||
Medical condition: Keratoconjunctivitis sicca (KCS), or dry eye syndrome | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: CZ (Completed) FR (Completed) ES (Completed) IT (Completed) DE (Completed) GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-005160-18 | Sponsor Protocol Number: RP101-200 | Start Date*: 2018-12-18 | |||||||||||
Sponsor Name:Redwood Pharma AB | |||||||||||||
Full Title: A Phase II, multicentre, randomised, placebo-controlled, double-masked trial of RP101 ophthalmic formulation versus vehicle in post-menopausal women with moderate to severe dry eye syndrome | |||||||||||||
Medical condition: moderate or severe dry eye syndrome | |||||||||||||
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Population Age: Adults, Elderly | Gender: Female | ||||||||||||
Trial protocol: AT (Completed) HU (Completed) DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2016-003497-40 | Sponsor Protocol Number: NVG16E128 | Start Date*: 2016-12-28 | |||||||||||
Sponsor Name:SANTEN SAS | |||||||||||||
Full Title: A PHASE IV, PROSPECTIVE, OPEN-LABEL, MULTICENTRE, SINGLE ARM, 3-MONTH PROOF OF CONCEPT STUDY TO ASSESS THE EFFECT OF IKERVIS® 1MG/ML (CICLOSPORIN) EYE DROPS ADMINISTERED ONCE DAILY ON THE QUALITY O... | |||||||||||||
Medical condition: Effect of one eye drop of IKERVIS®on adult male or female (aged 18 years or above) Dry Eye Disease patients with severe keratitis despite the use of tear substitutes. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-003131-31 | Sponsor Protocol Number: M19-956 | Start Date*: 2020-02-05 | |||||||||||
Sponsor Name:AbbVie Deutschland GmbH & Co. KG | |||||||||||||
Full Title: A Phase 2a, Double-Blind, Randomized, Placebo-Controlled Study of Ravagalimab in Subjects with Moderately to Severely Active Primary Sjogren’s Syndrome. | |||||||||||||
Medical condition: Moderately to Severely Active Primary Sjogren's Syndrome | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2012-001910-40 | Sponsor Protocol Number: OPHT-120312 | Start Date*: 2012-06-06 | |||||||||||
Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie | |||||||||||||
Full Title: The effect of intravenous glucocorticoids on the tearfilm in eyes with thyroid-associated ophthalmopathy | |||||||||||||
Medical condition: Thyroid-associated ophthalmopathy (TAO) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: AT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-002835-40 | Sponsor Protocol Number: AK701 | Start Date*: 2020-01-28 | ||||||||||||||||||||||||||
Sponsor Name:Akari Therapeutics Plc | ||||||||||||||||||||||||||||
Full Title: Topical rVA576 for treatment of atopic keratoconjunctivitis: a randomised placebo double masked parallel trial (TRACKER) | ||||||||||||||||||||||||||||
Medical condition: Moderate to severe atopic keratoconjunctivitis (AKC), Vernal keratoconjunctivitis (VKC), Severe allergic conjunctivitis (seasonal (SAC) or perennial (PAC)) | ||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: ES (Prematurely Ended) | ||||||||||||||||||||||||||||
Trial results: View results |
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