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Clinical trials for Topiramate

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    45 result(s) found for: Topiramate. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2018-000943-15 Sponsor Protocol Number: CAMG334ADE01 Start Date*: 2019-01-24
    Sponsor Name:Novartis Pharma GmbH
    Full Title: Randomized, double-blind, multicenter head-to-head study of erenumab against topiramate - migraine study to assess tolerability and efficacy in a patient-centered setting (HER-MES)
    Medical condition: Migraine prophylaxis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10027599 Migraine PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-001234-32 Sponsor Protocol Number: TOPMAT-MIG-3006 Start Date*: 2005-08-22
    Sponsor Name:Janssen Cilag International NV
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Topiramate for the Prophylaxis of Migraine in Pediatric Subjects 12 to 17 Years of Age. Estudio aleatoriz...
    Medical condition: Migraine in Pediatric Population (12-17 year olds, inclusive)
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) FI (Completed) NO (Completed) BE (Ongoing)
    Trial results: View results
    EudraCT Number: 2015-001223-23 Sponsor Protocol Number: CAPSS-311 Start Date*: 2015-04-24
    Sponsor Name:Johnson & Johnson Pharmaceutical Research and Development, L.L.C.
    Full Title: TOPAMAX (Topiramate) Initiated as Monotherapy in Epilepsy (TIME): A Multicenter, Outpatient, Open-Label, Study to Evaluate the Dosing, Effectiveness and Safety of TOPAMAX as Monotherapy in the Trea...
    Medical condition: New onset epilepsy
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2016-004955-64 Sponsor Protocol Number: E2090-S082-403 Start Date*: 2017-04-21
    Sponsor Name:Eisai Korea Inc.
    Full Title: A Multicenter Comparative Trial of Zonisamide and Topiramate as Monotherapy in Epilepsy Patients: Safety for cognitive function
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2015-001222-42 Sponsor Protocol Number: CAPSS-272 Start Date*: 2015-04-24
    Sponsor Name:Johnson & Johnson Pharmaceutical Research and Development, L.L.C.
    Full Title: A double-blind trial comparing the efficacy, tolerability and safety of monotherapy topiramate versus phenytoin in subjects with seizures indicative of new onset epilepsy
    Medical condition: New onset epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-004373-10 Sponsor Protocol Number: p08- Start Date*: 2008-04-08
    Sponsor Name:Top institute of Pharmaceutical Research
    Full Title: The effect of short term Topiramate treatment on insulin secretion, glucose- and lipid metabolism in obese women
    Medical condition: Obesity Diabetes Mellitus Metabolic syndrome
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012601 Diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004402-13 Sponsor Protocol Number: C08-01 Start Date*: 2009-03-17
    Sponsor Name:Inserm
    Full Title: Etude en neuropsychologie, imagerie fonctionnelle et pharmacologie des effets cognitifs chez l'enfant épileptique traité par le topiramate ou le clobazam
    Medical condition: Epilepsie partielle crypotgénique/ symptomatique
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015037 Epilepsy LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005696-17 Sponsor Protocol Number: 1645-CI-058 Start Date*: 2013-06-18
    Sponsor Name:Instituto de Investigacion Sanitaria La Fe
    Full Title: Multicenter, randomized, blinded clinical study comparing early use of total body moderate hypothermia plus topiramate or placebo in asphyxiated newborn infants evolving to moderate-to-severe hypox...
    Medical condition: Asphyxiated newborn infants evolving to moderate-to-severe hypoxic ischemic encephalopathy
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001552-19 Sponsor Protocol Number: TOPMATEPY4067 Start Date*: 2014-12-16
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Randomized, Active-Controlled, Open-Label, Flexible-Dose Study to Assess the Safety and Tolerability of Topiramate as Monotherapy Compared with Levetiracetam as Monotherapy in Pediatric Subjects ...
    Medical condition: New-onset or recent-onset epilepsy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed) IT (Completed) HU (Completed) BE (Completed) DE (Completed) GB (Completed) FR (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2005-001338-33 Sponsor Protocol Number: TOPMAT-PEP-3001 Start Date*: 2006-01-20
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Randomized, Double-Blind, Placebo Controlled, Fixed Dose-Ranging Study to Assess the Safety, Tolerability, and Efficacy of Topiramate Oral Liquid and Sprinkle Formulations as an Adjunct to Concur...
    Medical condition: Partial Onset Epilepsy and other Seizures
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) FI (Prematurely Ended) HU (Prematurely Ended) CZ (Prematurely Ended) ES (Completed) NO (Ongoing) BE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-008283-26 Sponsor Protocol Number: 0462-085 Start Date*: 2009-04-03
    Sponsor Name:Merck & Co., Inc.
    Full Title: Ensayo multicéntrico cruzado, aleatorizado, doble ciego, controlado con placebo para evaluar la eficacia y la tolerabilidad de rizatriptán 10 mg CBD en el tratamiento de la migraña aguda en pacient...
    Medical condition: Acute migraine Migraña Aguda
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066635 Acute migraine LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-004402-15 Sponsor Protocol Number: N01353 Start Date*: 2015-10-27
    Sponsor Name:UCB Korea Co.,Ltd.
    Full Title: A Randomized, Open-label, Parallel Group, Multi-center, Comparative, Phase IV Trial of Levetiracetam (LEV) Versus Topiramate (TPM) as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects...
    Medical condition: Refractory Partial Onset Seizures
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-001228-20 Sponsor Protocol Number: CAMG334A2401 Start Date*: 2019-04-11
    Sponsor Name:Novartis Pharma AG
    Full Title: A 12-month prospective, randomized, interventional, global, multi-center, active-controlled study comparing sustained benefit of two treatment paradigms (erenumab qm vs. oral prophylactics) in adul...
    Medical condition: Migraine prevention
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10027599 Migraine PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) CZ (Completed) FI (Completed) GB (GB - no longer in EU/EEA) SK (Completed) PT (Completed) GR (Completed) PL (Completed) ES (Ongoing) IT (Ongoing)
    Trial results: View results
    EudraCT Number: 2007-002929-78 Sponsor Protocol Number: CARISEPY3007- Amendment INT-2/GBR-1 Start Date*: 2007-11-13
    Sponsor Name:Ortho-McNeil Janssen Scientific Affairs, LLC
    Full Title: A Randomized, Double-blind, Parallel-group, Multicenter Study to Evaluate the Retention Rate, Efficacy, Safety, and Tolerability of Carisbamate, Topiramate and Levetiracetam as Adjunctive Therapy i...
    Medical condition: Partial onset seizures
    Disease: Version SOC Term Classification Code Term Level
    9.1 10034091 Partial seizures, simple LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) CZ (Prematurely Ended) BE (Temporarily Halted) FI (Completed) FR (Completed) IT (Prematurely Ended) ES (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2011-003432-32 Sponsor Protocol Number: P100116 Start Date*: Information not available in EudraCT
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.0 10010331 - Congenital, familial and genetic disorders 10036476 Prader-Willi syndrome PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002467-27 Sponsor Protocol Number: 2007 Neuro 12 Start Date*: 2008-01-24
    Sponsor Name:Salford Royal NHS Foundation Trust
    Full Title: Antidyskinetic Properties of Topiramate: A Double-Blind, Placebo-Controlled Trial in Patients with Parkinson's Disease and Levodopa-Induced Dyskinesias
    Medical condition: Patients with idiopathic Parkinson's disease and levodopa-induced dyskinesias
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029205 - Nervous system disorders 10013916 Dyskinesia PT
    13.1 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    13.1 10029205 - Nervous system disorders 10034005 Parkinson's disease and parkinsonism HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002195-40 Sponsor Protocol Number: 13/0656 Start Date*: 2014-09-02
    Sponsor Name:University College London
    Full Title: A randomised controlled trial of the ketogenic diet in the treatment of epilepsy in children under the age of two years
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2004-003945-41 Sponsor Protocol Number: N/A Start Date*: 2005-02-15
    Sponsor Name:liverpool university
    Full Title: Pharmacogenetics of GABAergic mechanisms of benefit and harm in epilepsy: : A prospective cohort study to determine the enviromental and genetic factors associated with response to clobazam.
    Medical condition: Epilepsy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-018627-25 Sponsor Protocol Number: 68/2009 Start Date*: 2010-02-25
    Sponsor Name:AZIENDA OSPEDALIERA MEYER
    Full Title: PHARMACOLOGY STUDY FOR EFFICACY OF TOPIRAMATE ASSOCIATED WITH HYPOTHERIMIA TREATMENT IN NEWBORNS WITH HYPOXIC ISCHEMIC ENCEPHALOPATY: A PILOT STUDY
    Medical condition: POST-ASPHYCTIC ENCEPHALOPATHY
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 SOC
    9.1 10029205 SOC
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006193-36 Sponsor Protocol Number: P091122 Start Date*: 2016-02-16
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004861 10027966 Morbid obesity LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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